KEGG   Rothia mucilaginosa: RMDY18_08130
Entry
RMDY18_08130      CDS       T01144                                 
Name
(GenBank) D-alanine-D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
rmu  Rothia mucilaginosa
Pathway
rmu00470  D-Amino acid metabolism
rmu00550  Peptidoglycan biosynthesis
rmu01100  Metabolic pathways
rmu01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:rmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    RMDY18_08130
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    RMDY18_08130
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    RMDY18_08130
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:rmu01011]
    RMDY18_08130
Enzymes [BR:rmu01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     RMDY18_08130
Peptidoglycan biosynthesis and degradation proteins [BR:rmu01011]
 Precursor biosynthesis
  Amino acid ligase
   RMDY18_08130
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 BiPBP_C
Other DBs
NCBI-ProteinID: BAI64645
UniProt: D2NSL9
LinkDB
Position
875068..876186
AA seq 372 aa
MTEKKTVALLCGGRSSEHPISLITAAGVLGAIDRTAYDVITIGITRDGRWYLTDEQQLAE
LTAGTRGTAEFPEGTQQVFLPMGAGDSRLTLVDAEGNVTRTAPVDVVFPLLHGPFGEDGT
VQGLLEMADLHYVGCGVTASAVGMDKHFMKVAFESAGLEVGPYEVVTNRQWEHEDREQIL
ERVLKLGFPMFVKPTRAGSSFGITKVDSVEELVPAIEEARRHDPKIIIEAGIVGREIECA
VLDGHHGEMPRASYPGEIEVVDQDHGFYDFEAKYVSESSAVTVCPANLPQDVQDRLRELA
VKAFLALDGEGLSRADFFYTEDGRLVINEVNTMPGFTPISMYKTMWENTGISYTDLISEL
LTLAMERPLGLR
NT seq 1119 nt   +upstreamnt  +downstreamnt
atgaccgagaagaagaccgtcgccctgctgtgcggtggccgctcctccgagcacccgatt
tcgctcattaccgctgctggcgttctgggcgctattgaccgcaccgcctacgacgtcatc
actatcggtattacccgtgacggccgctggtacctgaccgatgagcagcagctcgccgag
ctgaccgctggcactcgcggtaccgcagagttccccgagggcacccagcaggtgttcctg
ccgatgggtgccggcgattcccgcctgaccctggtggatgctgagggtaacgttacccgc
accgcaccggtggacgttgtgttcccgctgctgcacggccccttcggcgaggacggcacc
gtgcagggtctgctggaaatggctgacctgcactatgtgggttgcggcgtgaccgcatcc
gctgtgggtatggacaagcacttcatgaaggttgctttcgagtccgctggcctggaggtc
ggcccctacgaggttgtcaccaaccgccagtgggagcacgaggaccgcgagcagattctg
gagcgcgtgctgaagctgggcttccccatgttcgtgaagccgacccgcgcaggttcttcc
ttcggtattaccaaggtggattcggtggaggagctcgtgcccgcgattgaagaggcgcgc
cgccacgacccgaagatcattattgaggccggtattgtgggccgcgaaattgagtgcgct
gtgctcgacggccaccacggcgagatgccccgcgcatcctaccccggcgagattgaggtt
gtggatcaggaccacggcttctacgacttcgaggcgaagtacgtttctgagtcttccgct
gtgaccgtgtgcccggcaaacctgccgcaggacgtgcaggatcgcctgcgtgagctggct
gtgaaggcgttcctggcgctggacggcgagggtctgtcgcgtgcggacttcttctacacc
gaggatggccgcctggtcatcaacgaggtgaataccatgcccggcttcaccccgatttcg
atgtacaagaccatgtgggagaacaccggtatttcctacactgatctgattagcgagctg
ctgaccctggcgatggaacgacccctgggtctgcgctag

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