Rattus norvegicus (rat): 363577
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Entry
363577 CDS
T01003
Symbol
Itk
Name
(RefSeq) tyrosine-protein kinase ITK/TSK
KO
K07363
IL2-inducible T-cell kinase [EC:
2.7.10.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04062
Chemokine signaling pathway
rno04660
T cell receptor signaling pathway
rno04670
Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
363577 (Itk)
04670 Leukocyte transendothelial migration
363577 (Itk)
04062 Chemokine signaling pathway
363577 (Itk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
363577 (Itk)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
363577 (Itk)
Protein kinases [BR:
rno01001
]
Non-receptor tyrosine kinases
TEC family
363577 (Itk)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
PH
SH3_1
BTK
SH3_9
SH3_10
SH3_2
PH_8
SH3_3
ABC1
SH3_4
Motif
Other DBs
NCBI-GeneID:
363577
NCBI-ProteinID:
NP_001102295
RGD:
1311618
Ensembl:
ENSRNOG00000006860
UniProt:
A6HDR3
D4A7W7
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All DBs
Position
10:complement(31254667..31316004)
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AA seq
620 aa
AA seq
DB search
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKASLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQVMHDNYLLYVFAPDCESRQRWVLTLKEETRNNNSLVSKY
HPNFWMDGRWRCCSQLEKLAVGCAPYDPTKNASKKPLPPTPEDNRRSFQEPEETLVIALY
DYQTNDPQELALRRDEEYYLLDSSEIHWWRVQDKNGHEGYAPSSYLVEKSPNSLETYEWY
NKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIISENNPCIKHYHIKETND
SPKRYYVAEKYVFDSIPLLIQYHQYNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIQP
SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRSQRGLFAAETLLGMCLDVCEGMAYLEKACVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDISTGFRLYKPRLASPHVYQVMNHCWKEKPE
DRPPFSRLLSQLAEIAECGL
NT seq
1863 nt
NT seq
+upstream
nt +downstream
nt
atgaacaacttcatcctcctggaagaacagctgatcaagaagtcccaacagaagagaagg
acttctccctcgaattttaaagtccgtttcttcgtcttaacgaaagccagcctggcatac
ttcgaggaccgccacgggaagaagcgcacgttgaagggctccatcgaactctccagaatc
aagtgcgtggagattgtcaagagtgacattagcatcccgtgccactataaataccctttt
caggtcatgcacgacaactacctcctgtacgtgtttgctccagactgcgagagccgtcag
cgctgggtgctcacccttaaagaagaaacgaggaataacaacagcctagtatccaagtat
caccctaatttctggatggatgggcggtggaggtgctgttcccagctagagaagcttgcc
gtaggctgtgctccctacgacccaacgaagaatgcttcaaagaagcctcttcctcctact
cctgaagacaacaggcggtcatttcaggaacctgaagaaaccctggtcattgccttgtac
gactaccaaaccaacgatcctcaggagctcgcgctgcggcgtgatgaagagtactacctg
ctggacagctccgagatccactggtggcgggttcaagacaagaatgggcatgaaggatat
gcacccagcagttacctggtggaaaagtctccaaatagccttgaaacctacgagtggtac
aataaaagcatcagccgagacaaagctgaaaaacttcttttggacacaggtaaagaagga
gcattcatggtccgagattccaggacacccgggacatacacagtctctgtcttcaccaag
gccatcataagtgagaacaacccctgtataaaacattatcacatcaaagaaacaaatgac
agccccaagcggtactatgtggctgagaagtatgtgtttgactccatccctctcctcatc
cagtatcaccaatacaatggaggaggtttggtcactcgactccggtatccagtttgctcc
tggaggcagaaagcccctgtcacagcagggctaagatatgggaagtgggtgatccagccc
tcggagctaactttcgtgcaggagattggcagcgggcagtttggactggtgcatctcggc
tactggctcaacaaggacaaggtggccatcaagaccattcaggaaggggcgatgtcagaa
gaagactttatcgaggaggcagaagtcatgatgaaactctctcaccccaagctggtgcag
ctctatggggtgtgcttggagcaagcccccatctgcctggtgtttgagttcatggagcac
ggctgcctatcggattaccttcgaagtcagcggggtctctttgctgcagagaccctgctg
ggcatgtgcctggacgtgtgtgagggcatggcctacctagaaaaagcgtgtgtcatccac
agagacctggccgccaggaactgtttggtgggagaaaaccaggtcatcaaggtgtccgac
ttcggcatgacaaggtttgtccttgatgatcaatataccagctccacgggcaccaaattc
ccagtgaagtgggcatccccagaagtgttctccttcagccgctacagcagcaagtcagat
gtgtggtcatttggtgtactgatgtgggaagtcttcagcgaaggcaaaatcccatatgaa
aaccgaagcaattcagaggtcgtggaagacatcagcactggctttcggttatacaagccc
cgcctggcctcccctcatgtctaccaggtcatgaatcactgctggaaagagaaaccggaa
gaccggccacccttctcccggctgttaagccaactggctgaaatcgcagaatgtggactt
tag
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