Rhodococcus opacus B4: ROP_48130
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Entry
ROP_48130 CDS
T00882
Name
(GenBank) non-ribosomal peptide synthetase
Organism
rop
Rhodococcus opacus B4
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Condensation
AMP-binding
PP-binding
AMP-binding_C
PapA_C
WS_DGAT_cat
LAL_C2
Motif
Other DBs
NCBI-ProteinID:
BAH53060
NITE:
ROP_48130
UniProt:
C1BBK7
LinkDB
All DBs
Position
5176612..5193411
Genome browser
AA seq
5599 aa
AA seq
DB search
MPVVGRALSTDDRITMSPDHSAAARTQHHSAGSASSSTGTGSTPVALPVTAAQSEVWVGQ
QLNPGSPVFNLSLVVEVAGPIDLDRTVAAIRKTVERADALHVRFERGEGNELLQVPTAPG
DWTLSVVDLRRDVDPETSARAWMDRDMETVVGIEGDEPLFRHALLRTGDESVIWYQRYHH
SLIDGYGITLLVADVVDRYEHPELATSTAPWPLDTLVISDRDYRASKRFESDRDFWLRQV
VDAPEPPRLLPQVVDHSGTPISALVEIDGDDADALYAFASDAGIRRTRLPLAAVVAYIHR
LTGRRDLTLSLPMTARVGRELRRIPGMCSTILPLRVQVDPEMTVGELATRIDTTLISVLR
HGRYRGEDLARELRSIDPDRQIFGPGINSMMFEHALTFGGFPAWVRGSATGPVRDLDFSI
RGGQDSEPIQIDLRAPAGLGAELEAHRRRLEHFVGQFVADPAQPIASLDPMTQAERRQLL
VEFNDTATARESATVPELFHAQVLRTPDAEALIAGDVRLTYRDLGERVAQLTRHLLDRGV
GPETVVAIGLPRSAEMVTGLLAVMCSGGAFVPLDPSWPQDRRTSVLADAGASLVLTGPGG
VTDAGERAVPVDLASWAYAEQPTEPPTVTVQGARLAYVIFTSGSTGRPKGAMIRHEAVCA
RLLWQRDEILGFGPADASLFKAPLSFDISVNEILLPLVSGGRLVVAEPGGERDPQYLLDL
IARESVTFVYLVSSMLDVLLDLSRGTDHLSALKHVWCGGEVLTPRLFERFRAQLAITMYH
GYGPAEATIGVSHVIYREDAARIATSIGRPNPDTQLYVLDEHLNPVPLGTGGELYAGGFL
LGRGYVDAPGLTASRFVANPFATDGSRLYRTGDLARWAPDGSLDFLGRADNQVKIRGMRL
ELEDVEAGIVSHPAVRHSAVVVRETPSGAKYLAAYVVAKQGSVPDVAELRAWASSKLPEY
MVPSAFVILDRFPLTPNGKLDRRALPEPDLGAAGENVAPRTAAEETLCALMAGVLGVESV
GVTDDFFALGGDSIVAIQLVNHARREGLSISPREVFQLRTAEALARAQDGRTAAAVDSDD
IAVGDVRCTPILARTAARGGEIAAFHQSVLVQTPAALDESAARTALAAVLERHDALRATL
VRGEQWMLSVPEPAPASMDGILRVVEFDGSAEQLDSETQAAVARLDPDAGTMLQAVLFSA
AEGPGRLLLIGHHLVVDGVSWRIILEDLARAGTAVTAGGVPELPPVGTSLRRWSELLDEH
TKSGAFDHELSFWSDAAATPDPLLGSRALDPALDLAGDAETLTVTLPPEFTGPLLSTVPA
AFHGHVKDALLTGAAVALRRWRNGEPGPVLLDVEGHGREEDLVRRTDGPAIDLSRTVGWF
TTVYPVVLDPGAAADEAGIADALKMVKDQLRRVPGAGFGYGALRYLGAAEPEFGQEPTPQ
VLFNYLGRVTSGTGADWLPRAMGGADDPRMPLGHALAFDVIAEDGADGPVLRTTLTWAPG
VLTRDAVRVLADEWTAVLRVLAGVGHLGGQTPSDFPLVSLTQPDVDALAGAADVLPLTPL
QDGIYFQSAFDDTGADPYVVQQVIELTGPVDAAALHRGLQAVVDRHAALRAGVRAVSDGR
VVQVIGDDVRVPMEVLDLTGVADPAQRVEEVLTADRARGFDFGRGPLLRYTLARLDGTKF
LLLQSIHHLVADGWSVPVMLRELMALYSVEGKPLALPTPTPYRNYLEWLGARDRQASLAV
WREALADAPEPVELPAPTPKGEFGIRSVRVALPSEATAALTAVGRARGLTLSTLVHGTWG
LVLGRLTGREDVLFGSTVSGRGGDLPGIETMVGLFINTVPARLRYRPTDTVAGALARWQH
EQSTLLDHQYLGLAELRREAGLQNLFETLVVFENYPLGDGAVADPSGAIQLTGIRFDEHP
PYAMTLIVVPGDALTLELKYDAARVDRATAARFAESTIAYLAELTRDVDQTVSAVALASR
EPIEAALRDVEVEFPDTTVTALLEEQAERTPDAVAVVFEDDHLTYAELHARANRLARLLV
ERGVAPESKVAVALPRSLDLMVALLAVGKAGGAYVPLDTGYPADRLAYMLADAQPVCVLT
DGTVPLAGSGVPEVRVADADRYSPEPLTGIALAPQHPAYVIYTSGSTGRPKGVVVPHAGI
VNRLLWVQRFRPITASDNVFQKTPSSFDVSVLEFFGPLLAGATLVLARPDGHKDPAYLAD
VIVRQSITRVHFVPSMLEVFLADPAAARCTGLRIISCSGEALPVASARRVAELLPGVELD
NLYGPTEASVDVSYAASVQGIEAAAPSVPIGLPTSNTGLYVLDRYLQPVPAGAAGELYLS
GPQLARGYLGRPGLSAERFVADPFSRNGSRMYRTGDVARVNADGAVEYLGRIDDQVKLRG
FRIELGEIEARMADCPGVRQAAAVVRSDRPGQQQLVGYVVGDADPGDVRARLASALPEFM
VPVAFVNLAEFPLGPSGKLNRKALPAPDFAAQATAEPAVESGTAGMLAAHYAEVLGLGEV
GVDDDFFALGGDSILAIRLVNLARREGITVTPRQIFEQRTPAALARLVADPAVAQPPRVE
DSGIGVLLPLPVVHRLSEWSGGKNRFNQAVLLHTPAGTDATVLTAALHAVIGHHDGLRQK
LTRHAPGVWSLEIAATADLTLRRVDVTGLDADALRETVAAESDAAADRLNPDDGIMLSAV
WFDAGPRELGRLLLVAHHLVIDGVSWRTLIEDLAMAWVAADSGENAALDPVPTSLRGFTR
VVTEQAQEPARLAELDHWLRVTGPGADLVPGTEGHAVVSGGARRTVCLDRQLTTALLTTV
PAVVGADVTDVLLAALRLSADRWLAERGRANDLLVDLERHGREELAAGVDLSRTVGWLTN
VTPVRLRSRAGALDTLKDVKEQLRGAPDGGIGYGMLRYVNARTAGLLAARSESQVLFNYL
GRMPHTPPGPWTQAVESDSLATDPDADLGGPYRLVINALCEESAQGAELQAVFAWSEADL
SEADTVALSDGWVAALRELADAAAEYDGPAMLTPSDLPLVTLTQEEIDQIVQASPSGVDT
VLPLSPLQEGLYFQAGFDSGNDIYTAQFSLDFEHRLDTDRLAAALRTLQRRNPTLRAGFV
SAGLPAPVQFFGTGLDVPVSEFDLRELDETERDSYAAQLTAQDRLTPFDLTSPPLWRAMV
LRLGDSHDRLVINRQFLLWDGWSNGIVVGQLLALYESGGDDSGFPAPEGSFEDYLQWLAT
RDADAAQSAWTDALGGLDEPTLLAATITGDPEPPQRRDAVLPEDLSERLRAGARGAGVTF
NAVLNAALAVVLGIETGRRDLVFGTTVAGRPPEVPGIDAVTGMFLNTVPVRTTLRPDETV
ADLLRRIQSERLALTPYDYLGLASIQRVSEHRQLFDVLYVLQNFVDEKQVSALNAAHDIS
GGDSIDHTHYPVTVVVTPGASVKVKFEFHPEKIPASRVERMLSRYVTVLEEWSTDLSGPV
GGIAGAALPVPAEPKALPDATIADLFAEAALVRPGETALVFGDRAVSYAELDADVNRMAR
LLLGHGAGPERIVALALPRTVEMVVALFAVLRTGSAYLPLELDHPAERLVAMLDDARPAV
LVTTSDVAGTLAAAAVDTLAVDTLDLGAVGSAPLSEAELGGFAPGTPGRLDHPAYVIYTS
GSTGKPKGVVTPYRGLTNMQFNHREAIFEPVVAAAGGRRLRIAHTVSFAFDMSWEELLWL
VEGHEVHICDENLRRDAEALVAYCDTHEIDVVNVTPTYAQHLIEEGLLDDGPGRHRPPLV
LLGGEAVSDSVWNRLRDTDGTCGYNLYGPTEYTINTLGAGTADSATPTVGTPIWNTSAYV
LDAWLRPVPDGVPGELYISGVGLARGYLDRFALTAERFVADPFRESVRMYRTGDLVRRAS
DGNLDFLGRTDDQVKIRGHRVELGEIASALEALDGVRQAAVVVDSGPGGFKRLVGYAVVS
TCQPPDVNNYSRALRATLPDYMVPAAVIEVDGLPMTVNGKLDVKALPSADDVLGRSGGVR
TEPRTDTERVLCELFGDILGVPVPGVDDDFFDLGGHSLLATRLISRARAALDADLTMRDL
FEAPTVAELAARIGEDTASTRPVLAAGPRPEHLPLSAAQQRLWLLQQMEDASAAYNFPIV
LRLQDALDPEVFEQALTDVVSRHESLRTVFGEHDGEPVQVILDGVRPGVAVVDGTEADVV
RLVTETVGRPFDLATEIPVRASLIRLGDQQVLAIVLHHIATDEWSDRPFLRDLMTAYAAR
AQGSAPGWAPLAVQYADYTLWQRDVLGDPQDPSSLVSRQLDYWARTLDGAPEELVLPADR
TRPARPSFAGGAIETTLDAETTRALRSLARTSGTSMFMVLHAAAAALLHRLGAGDDLPIG
APVAGRSEQGLDDLIGFFVNTVVLRTDVSGNPTFDQLLARVRDTDLAAFAHSDVPFETVV
EKVNPARTLARNPLFQVMAGYHSRTSDSAQAAGSALTPVVFEERTAKFDLVFNFTEYLDD
DRVELRLEYGSDLFDKDTAEKIARRQVAVLGAVASDSGLAVGDLDVFLGGERELVVHGFN
DTAQPVAEETFYEAFARHVAATPDAVAVVDAAGAVTYAELSARADRIAGLLHRRGVSAEG
VVGLAVPRSSQMVAVVLGVLKLGAAYLPLDLNHPSDRISYMLADSAARVLVTTAGESPRI
AEVDGLVRVLLDDAAVAAELDTEHGTQVPPAPQGLDHAAYVIYTSGSTGKPKGTILTHDG
IPSLVATAEQRMKLVPGSVVMQFASIGFDVAVFELSMALCTGSRLVIVPDESRVAGSELT
DFMAAHSVTHAIIPPSLLAALPAGCDVPEGCTVLVGTETVPPELIGRWAERLNLLAAYGL
TEATVNNTLWQAQPGWNSAVPIGIPDPNEQAYVLDDLLQPVPPGVAGELYIAGRGLARGY
LGRPDLTSVRFVPSPFGGAGTRMYRTGDRARWRADGNIDFLGRVDDQVKIRGFRIELGEI
IAALGSHSAVKQSAVVADRSGDIVRLVGYVTPADGHGAEQIDPQAVREHAAARLPDYMVP
TLVVVLDGDLPLTPNGKLDRRALPLPDWSALTGDGTPQTPEQKEIAAAFAEILHLPSVGI
HDNFFDLGGNSMASMRLVGRIRGRFAVDIGIRDVFDSSTVAELSAIVAAATSTGRPVLTV
ADPRPETLPVSGPQRRFWKQFRAAGADARASHALSLQLRDTVDPEILAQALDDVTSRHEP
LRTVYVEVGDTVFAQEAVRPRLELVDVGDGDVHRTVFEDVHRTVFEDVHRTVFELAQQPL
DLTGHAPLRVHLVTGADGTQALLLAMHYIAVDEWSVVPLLGDLMGAYAARSQGEEPEWEP
LPVGYADYVVWSQALAGAPGDPDSRRSRQLAYWRETLDGMPSRLELPAPAVRGPRTAEIV
PVEIDAELHSAAQKFAGDTGTSLFMVLQAALATVLTRHGAGTDIPLGSLVAGRTEEALDA
LVGCFFNIVLLRTDTSGDPDPVQLLQRIRAANLDALDNQDVAFADVAEALGDTPVLRPQV
MIVHHEQARLGHLDALGGFMPVPVGVPDSDLTLSFYEPIGDGPVHAYFSFSSDVLDAEEV
RGWASELSTLVTAWAEGAR
NT seq
16800 nt
NT seq
+upstream
nt +downstream
nt
gtgcccgtcgttggacgggcgctctcgacggacgatcggatcaccatgtctccggaccac
tcggcggctgcgcgcactcagcaccactcggctgggagcgcttcttcctcgaccggcacc
ggttcgacgcctgtcgcgctgccggtgacggccgcgcagtccgaggtgtgggtcgggcag
cagctgaacccgggcagcccggtcttcaacctctcgctcgtcgtcgaggttgcgggcccg
atcgatctggaccggaccgtcgcggcgatccggaagaccgtcgaacgggccgatgccctg
cacgtgcgtttcgagcgcggcgaaggcaacgaactgctgcaggtgccgacagcgcccggc
gactggacgctgagcgtcgtggacctgcgccgcgacgtggatcccgagacgagtgcgcgc
gcgtggatggaccgcgacatggagaccgtcgtcggcatcgagggcgacgaaccgctgttc
cggcacgctctcctgcgcaccggggacgagtcggtgatctggtaccagcgctaccaccac
agcctcatcgacggctacggcatcaccctgctcgtggcggacgtcgtcgatcgatacgag
catccggaactcgcgacgtccacggcgccgtggcccctcgacaccctcgtgatctccgac
cgcgactaccgtgcctcgaagcgcttcgaatccgaccgcgacttctggctccggcaggtc
gtcgacgcgccggagccgccgcggctgctgccgcaggtcgtcgaccactcggggacgccg
atctccgccctcgtcgagatcgacggggacgacgccgacgcgctctacgcgttcgcctcc
gacgccgggatccggcgcacccgcctgccgctcgccgcggtcgtggcgtacatccaccgg
ctcaccggccgccgcgacctcacgttgtcgctgccgatgacggcgcgggtcgggcgcgaa
ctgcgccgcatcccggggatgtgctcgacgatcctgccgctccgggttcaggtggatccc
gagatgacggtgggtgagctcgccacccgcatcgacacgacgctgatctcggtgctgcgg
cacgggcgctaccgcggtgaggacctcgcccgcgaactgcggtcgatcgacccggaccgt
cagatcttcggtcccggaatcaattccatgatgttcgagcatgcgctgacgttcggcggg
ttcccggcgtgggtgcggggttcggcgaccggaccggtccgcgacctcgacttctcgatc
cgcggtgggcaggattcggagcccatccagatcgacctgcgggcgccggccggtctcggg
gccgagctcgaggcgcatcgccgcaggctcgagcacttcgtcggccagttcgtcgccgac
ccggcgcagcccatcgcgtcgctcgatccgatgacccaggcggagcggcggcagttgctg
gtggagttcaacgacaccgcgaccgcacgggaatcggcgacggtgcccgaactgttccac
gcccaggtgttgcgcacacccgatgccgaggccctgatcgccggcgacgtccggctcacc
taccgggacctcggggagcgggtggcgcagctgacccggcacctcctggatcgcggtgtc
gggccggaaaccgttgtggcgatcggccttccgcgatccgcggaaatggtgaccggactg
ctcgccgtcatgtgctcgggcggggcgttcgtgccgctcgacccgtcgtggccgcaggac
cgccggacgtcggtgctcgccgacgccggggcctccctcgttctcaccggccccggcggg
gtcaccgacgcgggggagcgggccgtgcccgtcgacctcgcgtcgtgggcgtacgccgag
cagcccaccgaaccgcccaccgtgaccgtgcagggtgcgcggctggcgtatgtcatcttc
acgtcgggttcgacgggcaggcccaagggggccatgatccggcacgaggccgtctgcgcg
cgactgctgtggcagcgcgacgaaatcctgggattcggaccggcggacgcgtcgctgttc
aaggcaccgctgtcgttcgacatctccgtgaacgagatcctgctgccgctggtgtcgggt
ggcaggctggtcgtggccgagcccggcggggaacgggacccgcagtatctcctggacctg
atcgcgcgcgagtcggtgacgttcgtctacctcgtgtcctcgatgctggacgtcctgctc
gacctgtcccggggtacggaccacctgtcggcgctgaagcacgtgtggtgcggcggtgag
gttctcacaccccggctgttcgagagattccgagcgcaactcgccatcacgatgtaccac
ggttacggtccggcggaggcgacgatcggggtgtcgcacgtgatctaccgggaggacgcc
gcgcggatcgcgacgtcgatcgggcgcccgaaccccgacacccagctgtacgtgctggac
gagcacctgaacccggtgccgctcggcaccggcggtgaactgtacgccggcggattcctc
ctcggacgcggttacgtcgacgcaccggggctgacggcgtcccgcttcgtcgccaatccg
ttcgcgaccgacggttcccggctgtaccggaccggcgaccttgcccggtgggcgccggac
ggctccctcgacttcctcggccgcgcggacaaccaggtgaagatccggggcatgcggctc
gaactcgaggacgtcgaggcgggcatcgtgtcgcatcccgccgtccggcacagcgccgtc
gtcgtgcgggaaacgccctcgggtgccaagtatctcgcggcgtacgtcgtggcgaagcag
ggttcggtcccggacgtcgccgagctgcgggcctgggcgtcgtcgaagctgccggagtac
atggtgccgtcggcgttcgtgatcctcgaccggttcccgctcacccccaacggaaaactg
gaccggcgcgcactgcccgaaccggacctgggcgccgccggtgagaacgtcgcgccccgc
accgccgccgaggaaaccctgtgcgcactgatggccggcgtcctcggggtggagtcggtg
ggtgtcaccgacgacttcttcgcgctgggcggcgacagcatcgtcgcgatccagctggtc
aaccacgctcggcgggagggactctcgatcagcccgcgggaggtcttccagctccgcacc
gcggaggcgctcgcccgtgcgcaggacggccggaccgcggccgccgtggattcggacgac
atcgcggtcggtgacgtccgctgcacccccatcctcgcgcgcaccgccgcgaggggcggc
gagatcgccgcgttccatcagtcggtgctggtgcagactccggcggccctcgacgagagt
gccgcgaggacggccctggcggcggtgctcgagcggcacgacgccctgcgcgcgacgctg
gtccggggtgaacagtggatgctttcggtgccggaaccggcgcccgcctccatggacgga
atcctccgggtcgtcgaattcgacggcagtgccgagcaactcgacagcgagacccaggcg
gccgtcgcacggctcgacccggacgcgggcacgatgctgcaggccgtcctcttctccgcc
gccgagggccccggccggttgctgctgatcggtcaccatctggtggtcgacggggtgtcc
tggcgcatcatcctcgaagacctcgcccgcgcgggcaccgccgtgacggccgggggcgtc
cccgaactgcctccggtcgggacttcgctgcgccgctggtccgaattgctggacgagcac
acgaagtcgggcgcattcgaccacgaactgtcgttctggtcggacgcggccgccacaccc
gacccgctcctcggctcgcgtgcgctcgacccggctctcgacctcgccggtgacgccgaa
accctcacggtgacactgcctccggagttcacgggaccgctgctgtccacggtgcccgcg
gcattccacggccacgtcaaagacgcgctcctcaccggtgccgcagtggcgctgcggagg
tggcggaacggcgaacccggccccgtgctgctggacgtcgaggggcacggacgcgaggaa
gacctcgtgcgccgcaccgacggacccgccatcgacctctcccggaccgtcggctggttc
accaccgtctacccggtggtcctcgaccccggggccgcggcggacgaagcgggaatcgcc
gacgcgctcaagatggtgaaagaccagttgcgccgcgttcctggtgcagggttcggctac
ggcgccctgcgctacctcggtgccgcggagccggaattcgggcaggagccgacaccgcag
gtgctgttcaactacctcggtcgggtgacgtccggcaccggcgccgactggctgccgcgg
gcgatgggcggcgccgacgacccgaggatgccgctcggacatgccctcgcgttcgacgtg
atcgccgaggacggcgccgacggtccggtgctgcggacgacactgacgtgggcgcccggt
gtgctcacccgcgacgccgtccgggtcctcgccgacgaatggaccgcggtgctgcgggta
ctcgccggggtcggccacctcggcggacagacgccttcggacttcccgctcgtctcgctg
acccagccggacgtggacgcgctggcgggggcggccgatgtgctgccgctgacaccgctg
caggacggcatctacttccagtcggcattcgacgacaccggtgccgacccgtatgtcgtg
caacaggtgatcgaactgaccggacccgtcgacgcggcggcgctgcaccgcggactgcag
gccgtcgtcgaccggcacgcggccctgcgcgccggggtgcgggcggtctcggacggccgg
gtggtccaggtgatcggcgacgacgttcgggtgccgatggaggtactcgatctcaccggc
gtcgcggatccggcgcagcgcgtcgaagaagtgctgacggcggaccgggcgcggggcttc
gacttcggccgcggtcccctgctgcgctacacgctcgcccgcctggatggcaccaagttc
cttctgctgcagtcgattcaccacctcgtcgccgacgggtggtcggtgcctgtgatgttg
cgtgagctgatggccctgtacagcgtcgaggggaagccgctggcgctgccgacacccacg
ccctaccgcaactacctcgaatggctgggcgcgcgggaccgtcaggcctcgctcgcggtg
tggcgggaggcgctcgccgatgctcccgagccggtggaacttccggcacccaccccgaag
ggcgagttcgggatccgcagtgtccgggtggccctgccgtcggaggccaccgccgccctc
accgctgtcggccgggcccgcggactgacgctcagcacactggtgcacggcacgtggggc
ctggtcctcggccgcctcaccggccgcgaggacgtgctgttcggttcgacggtgtcgggt
cgcggcggcgacctgcccggcatcgagaccatggtgggcctgttcatcaacaccgttccc
gcccggctgcggtaccggcccaccgacacggtggccggggccctcgcccggtggcagcac
gagcagtcgacgctgctcgaccaccagtacctcggactggccgagctgcgccgggaagcg
ggactgcagaacctcttcgagacgctggtcgtgttcgagaactatcccctcggcgacggt
gcggtcgcggatcccagcggtgcgatacagctgaccggtatccgtttcgacgagcacccg
ccgtacgcgatgacgctgatcgtggtgcccggcgacgcgctgaccctcgagctgaagtac
gacgccgcccgcgtcgacagagcgaccgcggcccggttcgcggagtcgacgatcgcctat
ctcgccgagctgacccgcgacgtcgaccagaccgtgtccgccgtcgcgctggcgtcgcgt
gagccgatcgaggccgcactgcgcgatgtcgaggtggagttccccgacacgaccgtgacg
gccctgctcgaggagcaggccgagcggacgccggacgcggtggccgtcgtgttcgaggac
gaccacctcacgtacgcggaactgcacgcgcgcgccaaccgcctcgcccggctgctcgtc
gagcgcggggtggcacccgagtcgaaggtcgcggtggcactgccccgttcgctggacctg
atggtggcgctgctcgcggtcgggaaggcgggcggcgcctacgtcccgctcgacaccgga
taccccgcggaccggctggcgtacatgctggccgacgcgcagccggtgtgcgttctcacc
gacggcaccgtgccgctcgctggttccggcgtcccggaggtccgggtggccgacgccgac
cggtactcgcccgagccgctgaccggcattgcgctcgcaccgcagcacccggcctacgtg
atctacacatcgggttcgacgggacggcccaagggcgtcgtcgtgccgcacgccggcatc
gtcaaccgcctgctgtgggtccagcggttccgcccgatcactgcttcggacaacgtgttt
cagaaaaccccgtcgagcttcgacgtgtcggtgctggaattcttcggaccactgctcgcc
ggcgcgacgctcgtgctggcccggccggacggtcacaaggacccggcgtacctcgccgac
gtcatcgtgcggcagtcgatcacgcgcgtgcacttcgtcccgtcgatgctcgaggtgttc
ctcgccgacccggccgccgcccggtgcaccggtctgcggatcatctcctgcagcggcgag
gcgctgcccgtggcgtccgcgcggcgcgtcgccgaactgctgccgggagtggaactcgac
aacctctacggtcccaccgaggcgtcggtcgacgtcagctacgccgcgtccgtccaggga
atcgaggcggccgcaccgtccgtgccgatcggcctgccgacgtccaacaccggactctac
gtgctcgaccggtacctgcagcccgtgcccgcgggcgccgccggtgagctctatctgtcc
gggccgcaattggcccgcggttacctgggcaggcccggtctcagcgccgaacgattcgtc
gccgatccgttctcccgcaacgggtcccgcatgtaccgcaccggcgacgtcgcccgggtg
aacgcggacggcgcggtcgagtacctcggccggatcgacgaccaggtgaagctgcgcggg
ttccgcatcgaactgggcgagatcgaagcccggatggccgactgccccggcgtgcggcag
gccgcggccgtcgtgcgctcggaccgtcccggtcagcagcagctggtgggctacgtcgtc
ggggacgccgacccgggcgacgtccgcgcgcgcctggcctcggcgctgccggagttcatg
gtgcccgtcgcgttcgtgaacctggccgagttcccgctcggccccagcggcaagctcaac
cgcaaagcccttcctgcgccggacttcgcagcgcaggcaacggcggagccggccgtggag
agcggaacggccggaatgcttgcggcgcactacgccgaggtcctcgggctcggggaggtc
ggggtggacgacgacttcttcgccctcggcggagacagcatcctcgccatccgcctggtg
aacctcgcgcgccgggaggggatcaccgtcaccccgcggcagatcttcgaacagcggacg
ccggccgcgctcgcgcgtctggtcgcggaccccgccgtcgcgcagcccccgcgggtggag
gactcggggatcggcgtcctgctgccccttcccgtcgttcaccggctgtccgagtggagt
ggcggaaagaaccgcttcaaccaggccgttctcctccacaccccggccggcaccgacgcc
accgtgctcacggcggccctgcacgcggtgatcggccaccacgacggcctgcggcagaag
ctcacccggcacgcgccgggtgtgtggtcgctcgagatcgccgccaccgccgatctgacg
ctgcgccgggtcgacgtcaccggactcgacgccgacgcgctgcgcgagacggtggcagca
gaatccgacgccgccgccgaccggctgaaccccgacgacggcatcatgctgtcggcggtg
tggttcgacgccggcccgcgggaactgggcagactcctgctcgtcgcgcaccacctggtg
atcgacggggtatcgtggcggaccctgatcgaggacctcgccatggcgtgggtggcggcc
gacagcggcgagaacgcggcactcgacccggtgcccacgtcgctgcgcggattcacgagg
gtcgtcaccgagcaggcgcaggaaccggcacgtctggcagaactcgaccactggttgcgg
gtcaccggacccggcgccgacctggtgcccggcaccgaggggcacgccgtggtgagcggc
ggcgcccggcggacggtgtgcctggaccgccagctgacgacggccctgctgaccacggtg
cccgccgtcgtcggcgcggacgtcaccgacgtgctgctcgcggcgctgcgactgtcggcc
gaccgctggctcgccgagcgcggacgcgcgaacgacctgctggtcgacctcgagcggcac
ggacgcgaagaactcgccgcgggtgtggatctctcccgcacggtcggctggctcaccaac
gtcacccctgtccggttgcgcagccgcgcgggcgcactcgacacgctcaaggacgtcaag
gaacagttgcgcggcgcgcccgacgggggtatcggctacggcatgctgcggtacgtcaac
gcgcgtaccgccggtctcctggcggcacggtccgaatcgcaggtgctgttcaactatctg
ggccgcatgccgcacacaccgcccgggccgtggacgcaggcagtcgaatcggattcactg
gcaaccgatcccgatgccgacctcgggggcccctaccggctggtgatcaacgccttgtgc
gaggagtccgcgcagggcgccgaactgcaggccgtcttcgcctggtctgaggccgacctg
agcgaggccgataccgtcgcgttgagcgacggctgggtggccgcactgcgtgaactcgcc
gacgccgccgccgaatacgacggaccggcgatgctcacgccgtccgacctgcccctcgtg
acgctgacgcaggaggagatcgaccagatcgtccaggcgagcccgagtggggtcgacacg
gtgctgccgctgtcgccgctgcaggagggtctgtacttccaggccgggttcgactccggc
aacgacatctacacggcacagttctctctcgacttcgagcatcgactcgacaccgaccgg
ctcgccgcggcgctgcggaccctgcagcgtcgaaaccccacgctgcgagcgggattcgtg
agtgcgggcctgcccgcgccggtgcagttcttcggcaccggactggacgtgcccgtttcc
gaattcgacctgcgggaactcgacgagaccgaacgcgattcctacgccgcacaattgacg
gcgcaggaccggctgacaccgttcgacctgacctccccgccgctgtggcgggcaatggtg
ttgcggctcggcgattcccacgaccgcctggtgatcaaccggcagttcctgctgtgggac
ggttggtccaacggcatcgtcgtcggccagctgctcgccctctacgagtcgggcggcgac
gactccggcttccccgccccggaagggtccttcgaggactatctgcagtggctggccacc
cgcgacgccgacgccgcacagtcggcgtggaccgacgcgctcggcgggctcgacgagccg
acgctgctggccgcgacgatcaccggggacccggagccgccgcagcgccgggacgcggtg
ctgccggaggacctgagtgaacggctccgggccggtgcccgcggcgccggtgtcacgttc
aacgcggtactgaacgccgcactggccgtcgtcctcggaatcgagaccggacgccgcgac
ctcgtgttcggcacgaccgtggccggacggccacccgaggtccccggcatcgacgcggtg
acgggaatgttcctcaacaccgtcccggtccggaccacactgcgccccgacgagaccgtc
gcggacctgctgcggcgcatccagtccgagcggttggcgctgaccccgtacgactatctc
gggctggcctccatccagcgggtctcggagcaccggcaactgttcgacgtgctctacgtg
ctgcagaacttcgtggacgagaagcaggtgtcggcgctcaacgcggcgcacgacatcagc
ggcggcgacagcatcgaccacacgcactacccggtcacggtcgtcgtgacacccggcgcg
agcgtgaaggtgaagttcgagttccaccccgagaagatcccggcgtcgcgggtcgaacgc
atgctgtcgcggtacgtgaccgtgctcgaggagtggtccacggacctgtcgggtccggtc
ggcggaatcgccggtgccgcactgcccgtgccggccgagccgaaggccctgcccgacgcg
accatcgccgacctgttcgccgaggcggcgctcgtccgtcccggcgagacggccctcgtg
ttcggggaccgcgcggtgagctacgccgaactcgacgccgacgtgaaccggatggcccgg
ctgctgctgggccacggcgcgggaccggaacggatcgtcgcgctcgcactaccgcggacg
gtcgagatggtggtggcgctgttcgccgtcctgcgcaccggatccgcctatctgccactc
gaactggaccatccggccgagcggctcgtcgcgatgctcgacgacgcccggccggcggtc
ctggtcaccacgtcggacgtcgcggggacgctcgccgccgcagccgtcgacacgctggcc
gtcgacaccctcgacctcggcgcggtcggatccgctccgctgtcggaggccgaactcggc
ggattcgcgcccggaacccccgggcgcctggaccatccggcgtacgtcatctacacgtcc
gggtccaccggcaagccgaagggcgtcgtcaccccgtaccgcggactgaccaacatgcag
ttcaaccaccgtgaggcgatcttcgagcccgtcgtggccgcggcgggtgggcggcgactg
cgtatcgcccacaccgtgtcgttcgcgttcgacatgtcgtgggaggaactgctgtggctg
gtggaggggcacgaggtccacatctgcgacgagaacctgcggcgtgacgccgaggcgctc
gtcgcctactgcgacacccacgagatcgacgtcgtcaacgtgacgccgacgtacgcgcag
cacctgatcgaggagggtctgctcgacgacggcccgggccggcaccggccgccgctggta
cttctcggcggcgaggcggtgtccgattcggtgtggaaccggttgcgggacacggacgga
acgtgcgggtacaacctgtacggccccaccgagtacaccatcaacaccctcggagccggc
accgccgacagtgcgacgcccaccgtcggcacaccgatctggaacacgtccgcgtacgtt
ctggacgcctggctgcgtcccgtcccggacggcgttcccggtgagctgtacatctcgggg
gtcgggttggcccgcggctacctcgaccggttcgcgctgacggcggagcgtttcgtagcc
gacccgttccgggaatccgtacgtatgtatcggacgggtgacctcgtccgccgcgcatcg
gacggcaacctcgacttcctgggccgcaccgacgatcaggtgaagattcgcggtcaccgc
gtggaactcggcgaaatcgcctccgcgctcgaagcgctggacggcgtgcgccaggcggcg
gtcgtcgtcgattcggggccgggcgggttcaagcggctggtcggctacgccgtcgtgagt
acttgtcaaccgccggacgtcaacaattactcacgggcgctgcgcgcaacgttgccggac
tacatggtgcccgccgcggtcatcgaggtcgacggcctcccgatgacggtcaacggcaaa
ctcgacgtcaaggcactgccgtccgcggacgacgtgctcggccgaagcggtggcgtgcgc
accgaaccccgcaccgacaccgaacgggtgctgtgcgagttgttcggtgacatcctcggc
gttccggtcccgggtgtcgacgacgacttcttcgacctcggtggtcattcgctgctcgcc
accaggctgatcagccgggcacgcgccgcgctcgacgccgacctcaccatgcgcgacctg
ttcgaggcgccgacggtggccgaactcgccgcccgcatcggcgaagacaccgcctcgacg
cgtccggtgctggcggccgggccacggcccgagcacctgccgctctccgccgcgcagcaa
cgcctgtggctgctgcagcagatggaggacgcatcggctgcttacaatttcccgatcgtc
ctgcgactgcaggacgcactcgaccccgaggtgttcgagcaggcgctgaccgacgtggtg
tcgcggcacgaatcgctgcgcaccgtgttcggggagcacgacggggaacccgtgcaggtg
atcctggacggcgtccgccccggcgtcgcggtggtggacggcaccgaggccgatgtggtc
cggctcgtcaccgagaccgtcggtcggccgttcgacctggccaccgagatcccggtgcgc
gcgagcctcatccggctcggcgaccagcaggtgctggcgatcgtgctgcaccacatcgcc
accgacgagtggtcggaccggccgttcctgcgggacctgatgacggcgtatgccgctcgc
gcgcagggttcggcaccgggctgggcgccgctcgctgtgcaatacgccgattacacactg
tggcagcgcgacgtcctcggtgatccgcaggacccgtccagcctcgtcagccgtcaactc
gactactgggcgagaactctcgacggggcgccggaagaactggtgctgcccgccgaccgc
acccgtccggcgcggcccagcttcgcgggcggcgccatcgagacgacgctcgacgccgaa
acgacgcgggcgctgcgttcgctcgcgcggacgtcgggcaccagcatgttcatggtgctg
cacgcggcggcggcggcgttgctgcaccgtctcggcgcgggcgacgacctgccgatcggg
gcgccggtcgccggccgcagcgaacagggcctcgacgacctgatcgggttcttcgtcaac
accgtggtgctgcggacggacgtgtcgggcaaccccacgttcgaccagttgctggcccgg
gtccgcgacaccgacctggcggcgttcgcgcactcggacgtcccgttcgaaaccgtggtg
gagaaggtgaatccggcgcggacgctggcccggaaccccctgttccaggtgatggccggc
taccacagccgcacgtccgattcggcgcaggcagccggatctgccctcacgccggtggtg
ttcgaggaacgcacagccaagttcgacctggtgttcaacttcacggagtacctcgacgac
gatcgggtggaactgcgcctcgaatacggttcggacctgttcgacaaggacaccgcggag
aagatcgcgcgcaggcaggtcgcggtgctcggcgccgtcgcgtccgactcggggctcgcc
gtcggcgacctcgacgtgttcctcggcggggaacgtgaactggtggtgcacgggttcaac
gacaccgcgcaaccggtggcggaggagacgttctacgaggcgttcgcacgccatgtcgcc
gcgacccccgacgccgtggccgtcgtggatgccgcgggcgcggtgacgtatgcggaactg
agtgcccgtgcggaccgcatcgccgggctgctgcaccgccgcggtgtctcggccgaaggc
gttgtgggtctggcggtcccgaggtcttcgcagatggtggcggtcgtgctcggggtgctg
aagctcggggcggcgtacctgccgctcgacctgaaccacccgtccgaccgcatctcctac
atgctcgccgactccgcggcgcgggtgctggtgacgacggcgggggagagcccgcgcatc
gcggaggtcgacggtctcgtccgcgttctcctcgacgacgccgccgttgccgcggaactc
gacaccgagcacggcacacaggtgccgcccgccccgcagggtctggaccacgccgcgtac
gtcatctacacctcgggctccaccggtaaaccgaagggcacgatcctcacccacgacggg
attcccagcctcgtcgccaccgccgaacagcggatgaagctcgtcccgggctcggtggtg
atgcagttcgcgtcgatcggattcgacgtggcggtcttcgagttgtcgatggcactgtgc
acgggctcccgactggtcatcgtgcccgacgagtcccgcgtcgccggatcggaactcacc
gatttcatggccgcgcattccgtgacgcatgcgatcattccgccctccctgctggcggcg
ctgccggccggatgcgacgttcccgagggatgcacggtgctggtgggcacggagaccgtg
ccgccggaactgatcggacggtgggccgaacgcctcaatctgctggccgcctacggtctc
accgaggcgaccgtcaacaacacgctgtggcaggcgcagcccgggtggaactccgctgtg
ccgatcggcatcccggaccccaacgaacaggcgtacgtcctcgacgacctcctgcagccg
gtgccgccgggtgtggcgggcgagttgtacatcgccggacgcggactggcccgcggatac
ctcggcaggcccgacctcacgtcggtccggttcgtgcccagccccttcggcggcgcgggc
acccgcatgtaccggaccggtgaccgggcgcgctggcgggccgacggcaacatcgacttc
ctcggacgcgtcgacgaccaggtgaagatccgcgggttccgcatcgaactcggcgagatc
atcgcggccctcggaagtcactcggccgtgaagcagtcggcggtcgtcgccgatcggtcc
ggcgacatcgtccggctcgtcggctacgtcaccccggccgacgggcacggggcagagcag
atcgatccgcaggcggtacgggaacacgccgctgcgcggttgcccgactacatggtgccg
actctcgtggtcgtgctggacggcgatcttccgttgacccccaacgggaagctcgaccgc
agggcactgccgctgccggactggtcggccctgacgggggacggcaccccgcagacgccg
gagcagaaggagatcgcggcggcgttcgccgagatcctgcacctgccgtcggtgggcatc
cacgacaacttcttcgacctcggcggcaactccatggcgtcgatgcggctggtgggccgg
atccgtgggcggttcgccgtcgacatcggcatccgggacgtgttcgacagttccacggtg
gcggaactgtccgcgatcgtcgccgcggccacgtccaccggcaggccggtgctgacggtg
gcggacccgaggccggagacgctgccggtgtccgggccgcaacgccggttctggaagcag
ttccgggcggcaggcgccgacgcgcgcgccagtcacgcactgtcgctgcagcttcgcgac
actgtggaccccgagatcctggcgcaggctctcgacgacgtcacgtcgcggcacgaaccg
ctgcggaccgtgtacgtggaggtcggcgacaccgtcttcgcccaggaggcagtgcggccc
aggctcgaactcgtcgacgtcggggacggcgacgtgcaccgcacggtgttcgaggacgtg
caccgcacggtgttcgaggacgtgcaccgcacggtgttcgagttggcgcagcagcccctc
gacctcaccgggcacgcaccgctgcgggtgcatctggtgaccggtgccgacggcacccag
gcgctgctcctcgcgatgcactacatcgccgtcgacgagtggtccgtggtgccgctgctc
ggtgacctgatgggcgcatacgccgcccggtcacagggcgaggaacccgaatgggaaccg
ctgcccgtcggatacgccgactacgtcgtgtggtcgcaggcactcgccggcgctcccggg
gacccggacagccgccggtcccgccagctcgcgtactggcgcgagacgctggacgggatg
ccgtcccgcctcgaacttcccgctccagcggttcgcggaccgcggacggcggagatcgtg
ccggtcgagatcgacgcggaactgcacagtgcggcccagaagttcgcgggcgacacgggc
accagcctgttcatggtgttgcaggcggcactcgcgaccgtgctgacacggcacggcgca
ggcacggacatcccgctggggtcgctcgtcgcgggacgcacggaggaggcgctggacgcg
ctggtcggctgcttcttcaatatcgttctgctgcgaacggatacgagcggcgatcccgat
cccgtgcagttgctgcagcgtatccgcgccgcgaatctcgacgcgctggacaaccaggac
gtggcgttcgccgacgtcgcggaggcgctcggcgacacgccggtgcttcgtccgcaggtc
atgatcgtgcatcacgagcaggccagactcggtcacctcgacgctctgggcggcttcatg
ccggtgccggtgggtgtgccggattcggatctgacgctgagcttctacgagccgatcggc
gacggacccgtccacgcatatttctctttctcctcggatgtgctggatgccgaagaggtc
cgtggctgggcgtcggagttgtcgacgctggtcaccgcatgggcggaaggagcccgatga
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