Rhinopithecus roxellana (golden snub-nosed monkey): 104660959
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Entry
104660959 CDS
T03989
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3 isoform X2
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro04062
Chemokine signaling pathway
rro04151
PI3K-Akt signaling pathway
rro04217
Necroptosis
rro04550
Signaling pathways regulating pluripotency of stem cells
rro04630
JAK-STAT signaling pathway
rro04658
Th1 and Th2 cell differentiation
rro04659
Th17 cell differentiation
rro05161
Hepatitis B
rro05162
Measles
rro05166
Human T-cell leukemia virus 1 infection
rro05169
Epstein-Barr virus infection
rro05200
Pathways in cancer
rro05203
Viral carcinogenesis
rro05223
Non-small cell lung cancer
rro05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
104660959 (JAK3)
04151 PI3K-Akt signaling pathway
104660959 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
104660959 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
104660959 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
104660959 (JAK3)
04659 Th17 cell differentiation
104660959 (JAK3)
04062 Chemokine signaling pathway
104660959 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
104660959 (JAK3)
05203 Viral carcinogenesis
104660959 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
104660959 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
104660959 (JAK3)
05161 Hepatitis B
104660959 (JAK3)
05162 Measles
104660959 (JAK3)
05169 Epstein-Barr virus infection
104660959 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
104660959 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rro01001
]
104660959 (JAK3)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
104660959 (JAK3)
Protein kinases [BR:
rro01001
]
Non-receptor tyrosine kinases
JAK family [OT]
104660959 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
Kdo
SH2
ABC1
Kinase-like
FERM_C_FAK1
LRR_RI_capping
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
104660959
NCBI-ProteinID:
XP_010359735
LinkDB
All DBs
Position
8:complement(17241500..17265764)
Genome browser
AA seq
1167 aa
AA seq
DB search
MTVAQETKGPTQEGAEWDFPLAASRLCSPFEGPGSLPARQVALMAPPSEETPLIPQRSCS
LLSTEAGALHVLLPARGPGPPQRLSFSFGDHLAEDLCVQAAKASGILPVYHSLFALATED
LSCWFPPSHIFSVEDASTQVLLYRIRFYFPNWFGLDKCHRFGLRKDLASAILDLPVLEHL
FAQHRSDLVSGRLPVGLSLKEQGECLSLAVLDLARMAREQAQRPGELLKTVSYKACLPPS
LRDLIQGLSFVTRRRIRRTVRRALRRVAACQADRHSLMAKYIMDLERLDPAGAAETFHVG
LPGVPGGQDGMGLLRVAGDGGIAWTQGEQEVLQPFCDFPEIVDISIKQAPRVGPAGEHRL
VTVTRTDNQILEAEFPGLPEALSFVALVDGYFRLTTDSQHFFCKEVAPPRLLEEVAEQCH
GPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQSPLGPDYKGCLIQRSPTGT
FFLVGLSRSHSSLRELLAACWDGRLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGCSPPTS
SLVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCRHEAVDGESRKTEVLLKV
MDAKHKNCMESFLEAASLMSQVSYRHLVLLHGVCMAGDSTMVQEFVHLGAIDMYLRKRGH
LVPASWKLQVVKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPA
VLSLEMLTDRIPWVAPECLREAQTLNLEADKWGFGATVWEVFSGVTMPISALDPAKKLQF
YEDRQQLPAPKWTELALLIQQCMAYEPVQRPSFRAVIRDLNSLISSDYELLSDPTPGALA
PRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCRYDPLGDNTGALVAVKQL
QHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRH
RARLDASRLLLYSSQICKGMEYLGSRRCVHRDLAARNILVESEAHVKIADFGLAKLLPLD
KDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYELFTYCDKSCSPSAEFLRM
MGCERDVPALCRLLELLEEGQRLPAPPACPAEVHELMKLCWAPSPQDRPSFSTLGPQLDV
LWSGSRGCETHAFTAHPEGKPHSLSFL
NT seq
3504 nt
NT seq
+upstream
nt +downstream
nt
atgacagtggctcaggaaaccaaggggcccacacaggaaggagccgagtgggactttcct
ctcgctgcctcccggctctgctctcccttcgaaggcccagggtccctgcctgctaggcaa
gttgcactcatggcacctccaagtgaggagacacccctgatccctcagcgctcctgcagc
ctcttgtccacggaggctggtgccctgcacgtgctactgcccgctcggggccccgggccc
ccccagcgcctatctttctcctttggggaccacttggctgaagacctgtgcgtgcaggct
gccaaggccagcggcatcctgcctgtgtaccactccctctttgctctggccacggaggac
ctgtcctgctggttccccccgagccacatcttctccgtggaggatgccagcacccaagtc
ctgctctacaggattcgcttttacttccccaattggtttgggctggacaagtgccaccgc
ttcgggctacgcaaggatttggccagcgctatccttgacctgccagtcctggagcacctc
tttgcccagcaccgcagtgacctggtgagtgggcgcctccctgtgggcctcagcctcaag
gagcagggtgagtgtctcagcctggccgtgctggacctggcccggatggcgcgagagcag
gcccagcggccaggagagctgctgaagactgtcagctacaaggcctgcctacccccaagc
ctgcgcgacctgatccagggcctgagtttcgtgacgcggaggcgtattcggaggacagtg
cgcagggccctgcgccgcgtggccgcctgccaggccgaccggcactcgctcatggccaag
tacattatggatctggagcggctggatccggctggggccgccgagaccttccatgtgggc
ctccctggggtccctggtggccaggacgggatggggctgctccgcgtggctggtgacgga
ggcatcgcctggacccagggagaacaggaggtcctccagcccttctgcgactttccagaa
atcgtagacattagcatcaagcaggccccgcgcgttggcccggccggggagcaccgcctg
gtcactgtcaccaggacagacaaccagattttggaggccgagttcccggggctgcccgag
gctctgtctttcgtggcgctcgtggacggctacttccggctgaccacggactcccagcac
ttcttctgcaaggaggtggcaccgccgaggctgctggaggaggtggcagagcagtgccac
ggccccatcactctggactttgccataaacaagcttaagactgggggctcacgtcctggc
tcctatgttctccgccgcagcccccaggactttgacagcttcctcctcactgtctgtgta
cagagcccccttggtcctgattataagggttgcctcattcagcgcagccccacagggacc
ttctttctggttggcctcagccgatcccacagcagccttcgagagctcctggcagcctgc
tgggatgggaggctgcatgtagatggggttgcagtgaccctcacctcctgctgtatcccc
agacccaaagaaaagtccaacttgatcgtggtccagagaggttgcagcccacccacgtcc
tccctggttcagccccaatcccaatgtcagctgagtcagatgacatttcacaagatcccc
gctgacagcctagagtggcatgagaacctgggccatgggtccttcaccaagatttaccgg
ggctgtcgccacgaggcggtggatggggagtcccgaaagacagaggtgctgctaaaagtg
atggatgctaagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagc
caagtgtcgtaccggcatctcgtgctgctccacggcgtgtgcatggctggagacagcacc
atggtgcaagaatttgtacacctgggggcgatagacatgtatctgcgaaaacgtggccac
ctggtgccagccagctggaagctgcaggtggtcaaacagctggcctacgccctcaactat
ctggaggacaaaggcctcccccacggcaatgtctccgcccggaaggtgctcctggctcgg
gagggggctgatgggagcccacccttcatcaagctgagtgaccctggggtcagccccgct
gtgttaagcctggagatgctcaccgacaggatcccctgggtggctcccgagtgtcttcgg
gaggcccagacacttaacttggaagctgacaagtggggcttcggtgccacggtctgggag
gtgtttagtggcgtcaccatgcccatcagcgccctggatcctgctaagaaactccaattt
tatgaggaccggcagcagctgccggcccccaagtggacagagctggccctgctgattcaa
cagtgcatggcctatgagccggtccagaggccctccttccgagccgtcattcgtgacctc
aacagcctcatctcttcagactatgagctcctctcagaccccacacctggtgccctggca
cctcgtgatgggctgtggaatggtgcccagctctatgcctgccaagaccccacgatcttc
gaggagagacacctcaagtacatctcacagctgggcaagggcaactttggcagtgtggag
ctgtgccgctatgacccgctaggcgacaacacaggtgccctggtggccgtgaaacagctg
cagcacagcgggccagaccagcagagggacttccagcgggagattcagatcctcaaagca
ctgcacagtgatttcattgtcaagtatcgtggtgtcagctatggcccgggccgccagagc
ctgcggctggtcatggagtacctgcccagcggctgcttgcgcgacttcctgcagcggcac
cgcgcgcgcctcgatgccagccgcctccttctctactcctcgcagatctgcaagggcatg
gagtacctgggctcccgccgctgcgtgcaccgcgacctggccgcccgaaacatcctggtg
gagagcgaggcccacgtcaagatcgctgacttcggcctagctaagctgctgccgcttgac
aaagactactacgtggtccgcgagccgggccagagccccattttctggtatgcccccgaa
tccctctcggacaacatcttctctcgccagtcagacgtctggagcttcggggtcgtcctg
tacgagctcttcacctactgtgacaaaagctgcagcccctcggccgagtttctgcggatg
atgggatgtgagcgggatgtccccgccctctgccgcctcttggaactgctggaggagggc
cagaggctgccggcgcctcctgcctgccctgctgaggttcacgagctcatgaagctgtgc
tgggcccctagcccacaggaccggccatcattcagcaccctgggcccccagctggacgtg
ctgtggagcggaagccgggggtgtgagactcacgccttcactgctcacccagagggcaaa
ccacactccctgtcctttttatag
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