Rhinopithecus roxellana (golden snub-nosed monkey): 104661963
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Entry
104661963 CDS
T03989
Symbol
HK1
Name
(RefSeq) hexokinase-1 isoform X2
KO
K00844
hexokinase [EC:
2.7.1.1
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00010
Glycolysis / Gluconeogenesis
rro00051
Fructose and mannose metabolism
rro00052
Galactose metabolism
rro00500
Starch and sucrose metabolism
rro00520
Amino sugar and nucleotide sugar metabolism
rro00524
Neomycin, kanamycin and gentamicin biosynthesis
rro01100
Metabolic pathways
rro01200
Carbon metabolism
rro01250
Biosynthesis of nucleotide sugars
rro04066
HIF-1 signaling pathway
rro04910
Insulin signaling pathway
rro04930
Type II diabetes mellitus
rro04973
Carbohydrate digestion and absorption
rro05230
Central carbon metabolism in cancer
Module
rro_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
rro_M00549
Nucleotide sugar biosynthesis, glucose => UDP-glucose
rro_M00892
UDP-N-acetyl-D-glucosamine biosynthesis, eukaryotes, glucose => UDP-GlcNAc
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
104661963 (HK1)
00051 Fructose and mannose metabolism
104661963 (HK1)
00052 Galactose metabolism
104661963 (HK1)
00500 Starch and sucrose metabolism
104661963 (HK1)
00520 Amino sugar and nucleotide sugar metabolism
104661963 (HK1)
09110 Biosynthesis of other secondary metabolites
00524 Neomycin, kanamycin and gentamicin biosynthesis
104661963 (HK1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
104661963 (HK1)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
104661963 (HK1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
104661963 (HK1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
104661963 (HK1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
104661963 (HK1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
rro04131
]
104661963 (HK1)
Enzymes [BR:
rro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.1 hexokinase
104661963 (HK1)
Membrane trafficking [BR:
rro04131
]
Autophagy
Mitophagy
Other mitophagy associated proteins
104661963 (HK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Hexokinase_2
Hexokinase_1
CSD
Sec23_helical
UvrD-helicase
Motif
Other DBs
NCBI-GeneID:
104661963
NCBI-ProteinID:
XP_010361121
UniProt:
A0A2K6NJM1
LinkDB
All DBs
Position
11:complement(136327058..136417512)
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AA seq
917 aa
AA seq
DB search
MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFKKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAAVKMLPSFVRSTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVATLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDRGLMCINMEWGAFGDNGCLDD
IRTQYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
NT seq
2754 nt
NT seq
+upstream
nt +downstream
nt
atgatcgccgcgcagctcctggcctattacttcacggagctgaaggatgaccaagtcaaa
aagattgacaagtatctctatgccatgcggctgtccgatgaaactctcatagatatcatg
actcgcttcaagaaggagatgaagaatggcctctcccgggattttaatccaacagccaca
gtcaagatgttgccaacattcgtaagatccattcccgatggctctgaaaagggagatttc
attgccctggatcttggtgggtcttcctttcgaattctccgggtgcaagtgaatcatgag
aaaaaccagaatgttcacatggagtccgaggtttatgacaccccagagaacatcgtgcac
ggcagtggaagccagctttttgatcatgttgctgagtgcctgggagatttcatggagaaa
aggaagatcaaggacaagaagttacctgtgggattcacattttcttttccttgccaacaa
tccaaaatagatgaggccatcctgatcacctggacaaagcgatttaaagcaagtggagtg
gaaggagcggatgtggtcaaactgcttaacaaagccatcaaaaagcgaggggactatgat
gccaacatcgtagctgtggtgaatgacacagtgggcaccatgatgacctgtggctatgac
gaccagcagtgtgaagtcggcctgatcatcggtactggcaccaatgcttgctacatggag
gaactgaggcacattgatctggtggaaggagacgaggggaggatgtgtatcaacacagaa
tggggagcctttggagacgatggatcattagaagacatccggacagagtttgaccgggag
atagaccggggatccctcaaccctggaaaacagctgtttgagaagatggtcagtggcatg
tacttgggagagctggttcgactgatcctggtcaagatggccaaggagggcctcttgttt
gaagggcggatcaccccagagctgctcaccagagggaagtttaacaccagtgatgtgtca
gccatcgaaaagaataaggaaggcctccacaatgccaaagaaatcctgacccgcctggga
gtggagccgtccgatgatgactgtgtctcagtccagcacgtttgcaccattgtctcgttt
cgctcagccaacctggtggctgccacactgggcgccatcttgaaccgcctgcgtgataac
aagggcacacccaggctgcggaccacagttggtgtcgacggatctctttacaagacgcac
ccacagtattcccggcgtttccacaagactctgaggcgcttggtgccggactccgatgtg
cgcttcctcctctcggagagtggcagcggcaagggggctgccatggtgacggcggtggcc
taccgcttggccgagcagcaccggcaaatagaggagaccctggctcatttccacctcacc
aaggacatgctgctggaggtgaagaagaggatgcgggccgagatggagctggggctgagg
aagcagacgcacaacaatgccgcggttaagatgctgccctccttcgtccggagtacccct
gacgggaccgagaatggtgacttcttggccctggatcttggaggaaccaatttccgtgtg
ctgctggtgaaaatccgtagtgggaaaaagagaacggtggaaatgcacaacaagatctac
gccattcctattgaaatcatgcagggcactggggaagagctgtttgatcacattgtctcc
tgcatctctgacttcctggactacatggggatcaaaggccctcggatgcctctgggcttc
acgttctcatttccctgccagcagacgagtctggacgcgggaatcttgatcacgtggaca
aagggttttaaggcaacagactgcgtgggccatgatgtagccaccttactaagggatgcg
ataaaaaggagagaggaatttgacctggacgtggtggctgtggtcaacgacacagtgggc
accatgatgacctgtgcttatgaggagcccacctgtgaggtcggactcattgttgggact
ggcagtaatgcctgctacatggaggagatgaagaacgtggagatggtggagggagaccgg
gggctgatgtgcatcaacatggagtggggggcctttggggacaatgggtgtctggatgat
atcaggacacagtacgacagactggtggatgaatattccctaaatgctgggaaacaaagg
tatgagaagatgatcagtggtatgtacctgggtgaaattgtccgcaacatcttaatcgac
ttcaccaagaagggattcctcttccgagggcagatctcagagccgctgaagacccggggc
atctttgagaccaagtttctctctcagatcgagagtgaccgattagcactgctccaggtc
cgggccatcctccagcagctgggtctgaatagcacctgcgatgacagtatcctcgtcaag
accgtgtgcggggtggtgtccaggagggctgcgcagctgtgtggcgcaggcatggctgcg
gtggtggataagatccgagagaacagaggactggaccgtctgaacgtgactgtgggagtg
gacgggacgctctacaagcttcatccgcacttctccagaatcatgcaccagacggtgaag
gaactatcaccaaaatgtaacgtgtccttcctcctgtctgaggatggcagcggcaaggga
gccgccctcatcacggccgtgggcgtgcggttacgcacagaggcaagcagctaa
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