Rhinopithecus roxellana (golden snub-nosed monkey): 104670476
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Entry
104670476 CDS
T03989
Symbol
PDE4A
Name
(RefSeq) cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoform X4
KO
K13293
cAMP-specific phosphodiesterase 4 [EC:
3.1.4.53
]
Organism
rro
Rhinopithecus roxellana (golden snub-nosed monkey)
Pathway
rro00230
Purine metabolism
rro01100
Metabolic pathways
rro04024
cAMP signaling pathway
rro04928
Parathyroid hormone synthesis, secretion and action
rro05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
rro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
104670476 (PDE4A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
104670476 (PDE4A)
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
104670476 (PDE4A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
104670476 (PDE4A)
Enzymes [BR:
rro01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
104670476 (PDE4A)
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Gene cluster
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Motif
Pfam:
PDEase_I
PDE4_UCR
Motif
Other DBs
NCBI-GeneID:
104670476
NCBI-ProteinID:
XP_010372071
UniProt:
A0A2K6P2E6
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Position
8:15415055..15465389
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AA seq
825 aa
AA seq
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MRSGAAPRARPRPPALALPPTGPESLTHFSFSDEDTRRHPQGRSVSFEAENGPTPPPGRS
PLDSQASPGLVLHAGAATSQRRESFLYRSDSDYDMSPKTMSRNSSVTSEAHAEDLIVTPF
AQVLASLRSVRSNFSLLTNVPVPNNKRSPLGGPTPVCKATLSEETCQQLARETLEELDWC
LEQLETMQTYRSVSEMASHKFKRMLNRELTHLSEMSRSGNQVSEYISTTFLDKQNEVEIP
SPTMKEREKQQAPRPRPSQPPPPPVPHLQPMSQITGVKKLMHSNSLNNSNIPRFGVKTNQ
EELLAQELENLNKWGLNIFCVSDYAGGRSLTCIMYMIFQERDLLKKFRIPVDTMVTYMLT
LEDHYHADVAYHNSLHAADVLQSTHVLLATPALDAVFTDLEILAALFAAAIHDVDHPGVS
NQFLINTNSELALMYNDESVLENHHLAVGFKLLQEDNCDIFQNLSKRQRQSLRKMVIDMV
LATDMSKHMTLLADLKTMVETKKVTSSGVLLLDNYSDRIQVLRNMVHCADLSNPTKPLEL
YRQWTDRIMAEFFQQGDRERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLV
HPDAQEILDTLEDNRDWYYSAIRQSPSPPPEEESRGPGHPPPPDKFQFELTLEEEEEEEI
SMASIPCTAQEALTAQGLSGAEEALDTTMAREASPAQESLDVMAQDESLEAELEEVYLTQ
QAQSTGSAPVAQDEFSSQEESVVAVSQSSPSALALQSPLLPAWRTLSVSEHAPGLPGLPS
TAAEVEAQREHQAAKRACSACTGTSGEDTSAFPAPGGGGSGGDPT
NT seq
2478 nt
NT seq
+upstream
nt +downstream
nt
atgcgctccggtgcagcgccccgggcccggccccggccccctgccctggcactgcccccc
acgggccccgagtccctgacccacttctccttcagcgatgaggatacccgtcggcaccct
cagggcagatctgtcagcttcgaggcagagaatgggccgacaccacctcccggccgcagc
cccctggactcgcaggcgagcccaggactcgtgctacatgccggggcggccaccagccag
cgccgggagtccttcttgtaccgctcagacagcgactatgacatgtcacccaagaccatg
tcccggaactcatcagtcaccagcgaggcgcacgctgaagacctcatcgtaacaccgttt
gctcaggtgctggccagcctccggagcgtccgtagcaacttctcactcctgaccaatgtg
cccgttcccaataacaagcggtccccgctgggcggccccacgcctgtctgcaaggccacg
ctgtcagaagaaacgtgtcagcagttggcccgggagacgctggaagagctggactggtgt
ctggagcagctggagaccatgcaaacttatcgctctgtcagcgagatggcctcgcacaag
ttcaagaggatgttgaaccgtgaactcacacacctgtcagaaatgagcaggtcaggaaac
caggtctcagagtacatttccacaacattcctggacaaacagaatgaagtggagatccca
tcacccacaatgaaggaacgagaaaaacagcaagcgcctcgaccaagaccctcccagcca
cccccgccccctgtaccacacttacagcccatgtcccaaatcacaggggtgaaaaagttg
atgcatagtaacagcctgaacaactctaacattccccgatttggggtgaagaccaatcaa
gaagagctcctggcccaagaactggagaacctgaacaagtggggcctgaacatcttttgc
gtgtcagattacgccggaggccgctcgctcacctgcatcatgtacatgatattccaggag
cgggacctgctgaagaaattccgcatccctgtggacacgatggtgacatacatgctgacg
ctggaggatcactaccacgctgacgtagcctaccataacagcctgcacgctgccgacgta
ctgcagtccacccacgtactgctggccacgcctgcgctagatgcagtgttcacggacctg
gagattctcgccgccctcttcgcggctgccatacacgatgtagatcaccctggggtctcc
aaccagttcctcatcaacaccaattcggagctggcgctcatgtacaacgatgagtcggtg
ctcgagaatcaccacctggccgtgggcttcaagctgctgcaggaggacaactgcgacatc
ttccagaacctcagcaagcgccagcggcagagcctacgcaagatggtcatcgatatggtg
ctggccacggacatgtccaagcacatgaccctcctggctgacctgaagaccatggtggag
accaagaaagtgacgagctcgggggtcctactgctggataactactccgaccgcatccag
gtcctccggaacatggtgcactgtgcagacctcagcaaccccaccaagccgctggagctg
taccgccagtggacagaccgcatcatggctgagttcttccagcagggtgaccgtgagcgc
gagcgtggcatggaaatcagccccatgtgtgacaagcacactgcttccgtggagaagtct
caggtgggttttattgactacattgtgcacccattgtgggagacctgggcagaccttgtc
cacccagacgcccaggagatcctggacactttggaggacaaccgggactggtactacagc
gccatccggcagagcccgtcgccgccacctgaggaggagtcaagggggccaggtcaccca
cccccacctgataagttccagtttgagctgactctggaggaggaagaagaggaagaaata
tcaatggcctcgataccgtgcacagcccaagaggcattgacagcgcagggattgtcagga
gctgaggaagctctggatacaaccatggcccgggaggcatccccagcgcaggagtcattg
gatgttatggcacaggatgagtccctggaggccgagctggaggaagtgtatttgacacag
caggcacagtccacaggcagtgcacctgtggctcaggatgagttctcgtcccaggaggaa
tccgtggttgctgtaagccagagcagcccctctgccctggctcttcaaagcccccttctc
cctgcctggaggaccctgtctgtttcagagcatgccccgggcctcccgggcctcccctcc
acggcggccgaggtggaggcccaacgagagcaccaggctgccaagagggcttgcagtgcc
tgcacagggacatctggggaggacacatctgcattcccagctcctggtgggggagggtca
ggtggagaccctacctga
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