Streptomyces albireticuli: SMD11_6571 Help Entry SMD11_6571        CDS       T05230                                  Name (GenBank) type I polyketide synthase   KO K19203   pimaricinolide synthase PimS1 Organism salj  Streptomyces albireticuli Pathway salj01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:salj00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     SMD11_6571  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:salj01008]     SMD11_6571 Polyketide biosynthesis proteins [BR:salj01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Pimaricinolide synthase      SMD11_6571 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt KR Acyl_transf_1 Ketoacyl-synt_C PKS_DH_N PS-DH KAsynt_C_assoc PP-binding adh_short Epimerase Thiolase_N Polysacc_synt_2 GDP_Man_Dehyd 3Beta_HSD PKS_DE ACP_syn_III Docking RmlD_sub_bind Motif Other DBs NCBI-ProteinID:  ARZ72147 UniProt:  A0A1Z2LCW4 LinkDB All DBs Position 7577885..7603342 Genome browser AA seq 8485 aa AA seqDB search MSNEEKLREYLKRAIADLHETRQQLGETEQKQREPIAIVSMACRFPGGVRSPEELWQLVR DGVDVVSSFPGNRGWDLEGLYHPDPDHPGTSYSREGGFLHDVGEFDPGFFGISPREALAM DPQQRLLLETAWEAVERAGIDPESLAGSSTGVFVGTGHDGYDDSARRTDEVGGHLLTGNL ISVASGRISYALGLEGPALTVDTACSSSLVALHLAAHSLRRGECSLALVGGATVMATPKL FVDFSRQRGLAADGRCKPFSAAADGTGWSEGVGLVVAERLSDALRNGHPVLAVLKGSAVN QDGASNGLTAPNGPSQQRVIRQALANAGLTAADVDAVEAHGTGTTLGDPIEAHALLATYG QQRPDDRPVLIGALKSNIGHTQSAAGIAGVMKMVMAMRHGELPGTLHLDEPSPHVDWAEG NARLLTAAEPWPETDRPRRAAVSSFGISGTNAHVVLEQAPPRETEPAPAPATRPGALPWI LSARTGDALRAQAARLARHVRTLPHLEPAAVAHSLVSARSLMEHRAAVVAEDRDAFLAGL DALAEDRTAAGLVTGVAAKAPLAFLFSGQGSQRPGTGRELYEAHPEFAKAFDAVCAELDP HLERPVRDVVLAEEGTADAALLDRTAYTQAALFALETALFRLVESWGMAPQFLAGHSIGE LTAAHVAGVLSLEDAARLVAARGTLMQALPEGGAMVAVQATEEEILASLAGHEDHAALAA VNGPDSTVISGDEETVALIAARWEERGRRTKRLRVSHAFHSPRMDGMLEDFRAVAESLTF HAPRIPVVSTVTGELATAEQLRSPEYWVRQVREAVRFHTAVRTLAAAGVTTFVEVGPRGV LTPMVQDSLAGLEEPVAVPLLRTGRPETQALAEAVATASAHGARVDWSACLGTPGATPVE LPTYPFQRQWYWLDPAGTTGEGPATEAGEAGFWEAVEGEDLEGLSAVLALDGNEADQLGS LLPTLSAWRRLRRTQATADGWSYRAHWTPLTTSTGPTATGNWLVVLPAAATDDPWAARLL DTLREQGLRTESFVLPEAGGFELPDGPFDGVLSLLALDEATHPDLPSVPRGLTATTALLR ALETADTRAPLWCVTRGAVAVDRRDPLTAPVQAQVWGLGRVVALESPQSWGGLVDLPENV DARIVSGLLDTLARGEDQVAVRPAGTFARRLARIAPGGDTGAGWTAHGTVLVTGGTGALG AELAHWLADAGAEHLLLLGRRGLEAPGARELAAALADRGTKVTVTACDAADRDALAAVLA GIPEDLPLTGVVHAAGVLDDGVLDALTPGHFETVLRPKATAARNLHELTQDLGLEMFVLY SSVAGVLGNAGQANYAAANAFLDALAEQRRGAGLPATSVAWGPWAEHGMATDGDLADRLS RDGLLPMAAGPALAALRQALAQDLTTVTVADIDWAAYAAALTAVRPNPLIGDLPEVRRAL DSGGRPRERRSPLRDRIGALPPAEQERALLQTVREEAAKVLGHPTPDTVDTQRAFREMGF DSLMAVELRNRVSAAVGLRLPATLLYDHPSCTAIAEYLREEILGTTGPAALVAPSAAALD EPVVIVGMACRFPGGVNTPDDLWRLLSEGEDAISPLPGDRGWDLDRLYHPDPDHQGTSYA RHGGFLDDAAGFDADFFGISPREALAMDPQQRLLLETTWEALEHAGIDPETLRGSSTGVF AGTNAQDYRTVLDAARDEVAGHALTGNAMSVISGRVSYTFGFEGPAVTVDTACSSALVAL HMAVQSLRSGECSLALAGGVTVMSSPSAFVEFSRQRGLAPDGRCKPFAAGADGTGWSEGA GLLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLSAPSGPSQQRVIRQALANADLTAA DIDAVEAHGTGTALGDPIEAQALLATYGQDRPEGRPLLLGAVKSNLGHTQAAAGAAGVMK MVLAMRHGVLPRTLHLDEPTPHVDWTDGTVELLTERTEWPGTGLPRRAAVSAFGISGTNA HVILEQPGTEEPETPADAPEAPATESGDTLPLLLSGRTEEALRAQAERLLSHLGAEPAPR LTDVAWTLATARTRFPHRAAVQAGDHDTAVRALTALAAGDADASLVTGTARTGKDAVLFS GQGSQRLGMGRELYARFPVFADAFDAVCAGLDEHLDRPLRDVVWGEDAELLNQTAYAQTA LFAIEVALFRLVESWNVRPEFVAGHSVGEIAAAHVAGVFSLTDACALVAARGRLMQALPS GGAMAAIRATEDEIRPHLNDDVTIAAVNGPSSVVVSGTEAAVEAVRSRFEDEGRKTSRLR VSHAFHSPLMDPMLDEFRAVAEGLAYGTPELTVVSNVTGAPATAEQLCAAEYWVTHVREA VRFADGVRALHTEGVTRLLELGPDGTLSAMARESLPDETATVPALRKDRPEETALLTALA HLHVQGAVADWAAFFTGTGAHTVDLPTYAFQHQRFWPTPGLTGPGDIGAAGLEAAGHPLL SAAVELSDSDGLLFTTRLSLQSHPWLADHVIMGSVLLPGTAFVELAVRAADEVGCDRIDD LTLAAPLVLPEHGGVQLQLRVGPADESGNRTLSARSRPEGDGDRPWTRHATGVLATAERA AEPGHDFRAGPWPPTGAEPVDVTGLYQGFADGGFDYGPHFRGLRAAWRRGDEVFAEVALP EVAEGDAPAYGLHPALLDAALHVCAFNGVDQGVVPFSWEGVSLHASGASAVRVRVVRHGA DAVSVDVADTEGGPVATVDTLTVRAVSADQLDGGASPVGRDALFHVTWNPLRLPPAGTAE TVATIGTLPGAPFDSHADVESLAGSGRVPGTVLAPVTPGSGDVVESAHATAARALDLIRS WLADDRLAESRLVFVTRGAVSGDDLAAATVWGLVRSAQSENPGRFGLVDLEGDADVTVLP RALASDEPQLLVRGGEAMAARLARAQTQARNAPAWDATGTVLITGGTGGLGRVMARHLVE RGVGSLVLVSRRGPAAEGAGELVAELRRNGAEATVEACDVTDRAAVADLVDRHGITAVVH TAGVLDDGVVGSLTPERLAAVMRPKVDAAWNLHEATKDLELDAFVVFSSVAGTIGSAGQG NYAAGNTFLDALAHHRRAAGLPAVSLAWGPWSQDGGMTGTLSEADLQRIARQGMPELTPA EGTALFDAALATDAALVLPVRFDLAELREQDDVPTLLRGLIRTRTRRSAVAGSAAASGLL GRLSGLGAAERRETLLDLVRAQVAVVLGHANPLTVDPARAFQELGFDSLTAVELRNRVNK ATGLRLSATAVFDYPTADALVGFLLDELFGGQPEERVPSLAGAPAATADDPVVIVGMSCR YPGGVASPEDLWRLVSDGVDAVSGFPADRGWDIESLYNPDPDALGTSYTRSGGFLHEAGD FDPEFFGMSPREALATDSQQRLLLESTWEAIERAGIDPATLRGSRTGVFAGVMYTDYSEI LVGDQYEGYRGNGSAASIASGRVSYTFGFEGPAVTVDTACSSSLVALHWAAQALRSGECS LALAGGVTVMSTPTTFVEFSRQRGLSADGRCKAFSDAADGVGWGEGVGMLVLERLSDARR NGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDAVEAHGTGTT LGDPIEAQALLATYGQDRPEDRPLLLGTVKSNIGHAQAASGVAGVIKMVMAMRHGVLPRT LHIDEPSSHVDWSAGAVELLTEPAEWPESGRRRAGVSSFGVSGTNAHVILEQPEPAEAAE TAPEPGSDVLPVVLSGRNEAALRGQAARLLSYVAGHDELPARDIGYSLAVGRSSFAHRAV VWGVERCDLVRALSAVAVGESGPGVVAGAVSAGKSAFLFSGQGSQRLGMGRELYARFPVF ADAFDAVCAGLDEHLDRPLRDVVWGEDAELLNQTAYAQTALFAVEVALFRLVESWGVRPE FVAGHSVGEIAAAHVAGVFSLTDACALVAARGRLMQALPTGGAMVAVQAEEAEVLPLLTE GVSIAAVNGPSSVVVSGAEEAVEAIRSHFAGEGRRTSRLRVSHAFHSPLMEPMLDGFREI VAGLSFGEPRIPVVSNLTGRLAESGQLASADYWVRHVREAVRFADGMSALEAEGVTRFLE LGPDGVLSAMARESVSEDAVLTPVLRKDRPEDTAALEALAQLYVQGVRVDWAAMFAGTGA RQVDLPTYAFQHERFWPSGGVARAGDVRFAGLGSAEHPLLGAAVELAGSGGLLFTGRLSV SSHAWLADHVVMGSVLVPGTALVELALRAADEVGCDLLEELTLAAPLVLPASGGAVQVQV WVGEPDESGRRSVAVHSRQGDEPWTLHAGGSVTTGAEPQRFDTTTWPPKGAEPVDVTGCY EQFAEAGFLYGPAFQGLQAAWKLGDDVFAEVRLPEGTDGAAYGLHPALFDAALHASAFGG GDDAGGVPFSWAGVSLHAAGASELRVRVRRVESGMSIAMADAAGAPVASVDSLALRPVSA DQLRTGDRDSLFTLDWAPVPLTDARVELATGPDGEPLRTYTDLASLADGEAPEVVLVAQD AGSAGAVESVHTGAAWALGLVRSWLADDRFAESRLVFVTRGAVSGDDLAGASVWGLVRSA QSESPGRFGLVDLGDDADTALLPQALATDEPQLLLRDGQALAARLARAETRVTAEVTWDT SGTVLITGGTGGLGRVMARHLVAERGVRSLLLVSRRGLAAEGAEELVAELAEQGADVKVE ACDVTDGAAVADLVARHSVTAVVHTAGVLDDGVISSLTADRLSAVLRPKVDAAWNLHEAT KDLDLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALARYRRAHGLPAASLAWGPWSQDSG MTGTLTEADLQRIARSGMPPLSAEEGVTLFDAALATAEPMLLPVRLDLAALRAQGEPQPL LRGLIRTRTRRTTASGSAAASGLVQRLAGLSEGERRAVLLDLVRERIAAVLGHARPETVD ASKAFQELGFDSLTAIELRNKLGKATGLRLSATAVFDYPTADALADHLLDELFGADTEEL LPVPALPPLTDDPVVIVGMSCRYPGGVTSPEDLWRLVSDGVDAVSGFPADRGWEIEDTYD PEREGAIATRSGGFLHDAAEFDPEFFGMSPREALTTDAQQRLLLETTWEALERAGMDPAA LRGSRTGVFAGVMYHDYSQLLAGREFEGYQGSGSAGSVASGRVSYTFGFEGPAVTVDTAC SSSLVALHLAAQSLRSGECSLALAGGVTVMSTPLTFVEFSRQGGLSPDGRCKAFADGADG VGWAEGAGILVLERLSDARRNGHRILATVRGSAVNQDGASNGLTAPNGPSQQRVIRQALA SGGLSTADVDVVEAHGTGTTLGDPIEAQALLATYGQHRPEDRPLLLGTVKSNIGHTQAAA GVAGVIKMVMAMRHGELPRTLHVDAPSSHVDWSAGAVELLTEPAAWPEGDRPRRAGVSSF GISGTNAHVILEQPEPEPAGPGEEPSDTEDLVPFVVSGKSAPALRAQAARLLSHLAHEPG QRLTDVAYSLATARSGFHHRAVVLAADRDALLRSLSALAEGRSEADIAAEGETRAGKRAF LFSGQGSQRLGMGRELYARFPVFADAFDAVCAGLDEHLDRPLRDVVWGEDAELLNQTAYA QTALFAVEVALFRLMEAWGVRPDHLMGHSVGEIAAAHVAGVFSLADACALVAARGRLMQA LPTGGAMAAIGAAEAEVLPLLTEGVSIAAVNGPSSVVVSGAEEAVEAIRSRFAGEGNRTS RLRVSHAFHSPLMEPMLDEFREVAERVTYGVPGIPVVSNVTGEPATTGQLGSAEYWVRHV REAVRFADGVRALEAQGVTEFLELGPDGALSALAADSAQDGAVFAPALRKDRAEEPALLT ALARLHVQGVPVDWAAVFAGTGARQVDLPTYAFQRARFWPAATGARSGDVRSAGLGSAEH PLLGAAVELAGSGGLLFTGRLSMSSHPWLADHVVMGSVLVPGTALVELALRAADEVGCDV LEELTLAAPLVLPVSGGGVQVQVWVGEPEESGRRSVAVHSREGDEPWTLHASGALTSGAE PVAFDTSVWPPKGAESVDVAGCYERFADAGFAYGPVFQGLQAVWKLGDDVFAEVRLPEGT DGAAYGLHPALFDAALHASMAAGGETEGAVPFSWTGVSLHASGASHIRVRIRDVDGGASL AIVDPAGAPVASVESLVVRPVSADQLRTGDRDSLFTLDWTGVQLTGEPLGSLAVLGEDTE HLLKELRLQTHADLEALAGNGVPDVVLVPASAGSAGTVESVHAATARALGLVRSWLADER FAESRLVFVTRGAVSGDDLAGAAVRGLVRSAQSESPGRFVLVDLEGDADVRVLSRALATD EPQLLIRDGQVLAARLARAETRSTADVVWDASGTVLITGGTGGLGRVMARHLVAEHGVRS LLLVSRRGPAAEGAEALVAELAGQGADVTVEACDVTDRAAVADLVARHSLTAVVHTAGIL DDGVVASLTADRLAAVLRPKVDAAWNLHEATEELDLDAFVVFSSVAGTFGSAGQANYAAG NAFLDALAHHRRARGLTAVSLAWGPWSQDGGMTGTLSDADIQRMARSGMPPLSAGEGAAL FDAALAATGPMVLPVRLDLAALRAQGEPQPLLRGLIRTRTRRTSASGSAVASGLVQRLTG LSTADRREVLLDVVRGKIAAVLGHAGSAEIDPTRAFQDLGFDSLTAVELRNRLNDVTGLR LPATAVFDYPTADAMVGLLLDELFGAEPVVSSPVRVPAVVTDDPVVIVGMSCRFPGGVTS PEDLWRLVSDGVDAVSGFPADRGWDVEALYNPDPEHTGTSYTRAGGFLKEAAEFDPSFFG MSPREALATDSQQRLLLETTWEALERAGIDPAALRGSQTGVFAGVMYNDYANLVSGPEFE GHQGSGSAGSVASGRVSYTFGFEGPAVTVDTACSSSLVALHLAAQSLRSGESSLALAGGV TVMSTPTTFVEFSRQRGLSPDGRCKAFADGADGVGWGEGVGMLVLERLSDARRNGHRILA TVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSTADVDAVEAHGTGTTLGDPIEA QALLATYGQDRPEDRPLLLGSVKSNIGHAQAAAGVAGVIKMVMAMRHGELPRTLHVDAPS SHVDWSAGAVELLTEPTAWPEGSGPRRAGVSSFGISGTNAHVILEQPARAEEPQAGADTD GLVPLVVSAKSPTALRAQAARLLSRLDADPGLRAADLAYSLVTARSSFGHRAVVWGAGRQ DVLRSLSALAVGETGTGVVAGAVGAGKSAFLFSGQGSQRLGMGGELYARFPVFAEAFDAV CAGLDEHLERPLRDVVWGEDAELLNRTAYAQTALFAVEVALFRLVESWGVRPEFVAGHSV GEIAAAHVAGVFSLTDACALVAARGRLMQALPTGGAMVAVQAEEAEVLPLLTEGVSIAAV NGPSSVVVSGAEEAVLAVVAHFENEGRKSSRLRVSHAFHSPLMEPMLDGFREVVAGLSFG EPRIPVVSNLTGRLAEPEQLASADYWVRHVREAVRFADGVQTLSAEGVTRFLELGPDGVL SAMARESLPEATAPVPLLRKNRDEEAAVFGALAELYVQGVRVDWAAMFAGTGARQVDLPT YAFQHERFWPSGGVARAGDVRFAGLGSAEHPLLGAAVELAGSGGLLFTGRLSVSSHAWLA DHVVMGSVLVPGTALVELALRAADEVGCDVLEELTLAAPLVLPVSGGGVQVQVWVGEPEE SGRRSVAVHSREGDEPWTLHASGALTSGAEPVAFDTSVWPPKGAESVDVAGCYERFADAG FAYGPVFQGLQAAWKLGDDVFAEVRLPEGTDGAAYGLHPALFDAALHASMAAGGDGAGAV PFSWTGVSLHASGASQVRVRLSLAEGGVSIAMADPAGAPVASVDSLVVRPISADQLRAGD RDSLFTLDWARVELTGEPLGSLAVLGEDAEGLLNGLSLPVHTDLDALTGADVPEAVLVAQ RLDAGDTVEAVHVATARALDLVRAWLADERFAESRLVFVTRGATSGENLAGAAVQGLIRS AQSENPGRFGLVDLDGDGDAAVEVKALPQALASDEPRLLLRDGQALAARLARVETQGIAD VTWDASGTVLITGGTGGLGRILARHLVTVHGVRSLLLVSRSGLAAQGAEELVAELAGQGA DVKVEACDVTDGAAVADLVARHSVTAVVHTAGVLDDGVIASLTADRLAAVLRPKVDAAWN LHEATKDLDLDAFVVFSSVAGTFGSAGQANYAAGNAFLDALAHHRRAAGLPAVSLAWGPW AQDGGMTGTLTDADLQRIARSGMPELSAEEGVALFDTAVAGAEPMLLPVRLDLAALRAQG EPLPLLRGLIRTRTRRTTASGTAAASGLVQRLTGLSSAEAREVVLETVRGQVAAVLGHDG AAEIDPDQAFQDLGFDSLTAIELRNRLSTLAEVRLPATLLFDYPTPAELVDHLLTRIAPE SASGPEALLSELDRLEKAFGGLDVTEEAHEQIAGRLEVLMAKWGALRDAGAGADREAASD DEDFDFDSASDDEVFDLLDNELGLS NT seq 25458 nt NT seq  +upstreamnt  +downstreamnt atgtccaacgaggagaagctgcgcgagtacctcaagcgcgcgatcgcagatctgcacgag actcgccagcaattgggcgagaccgagcagaagcagcgcgagcccatcgcgatcgtctcc atggcctgccgcttccccgggggcgtgcgctcaccggaagagctgtggcagctggtccgg gacggcgtcgacgtggtctcctccttccccggcaaccgtggctgggacctcgaagggctc taccaccccgacccggaccacccgggcacctcctactcccgtgagggcggattcctccac gacgtgggcgagttcgaccccgggttcttcggcatctcgccgcgcgaggcgctcgccatg gacccccagcagcggctcctcctggagaccgcctgggaggccgtcgaacgggccggcatc gacccggagtccctcgccggcagcagcaccggagtgttcgtcggcaccggccacgacggc tacgacgacagtgcccgccgcacggacgaggtcggcgggcacctgctgaccggcaacctc atcagcgtcgcctccggccggatctcctacgccctcggtcttgagggccccgccctgacc gtcgacacggcctgctcctcctcgctggtggcactgcacctggcggcgcactcgctgcgc cggggcgagtgctccctcgccctcgtgggcggcgcgaccgtgatggccaccccgaagctg ttcgtggacttctcccgccagcggggcctcgccgccgacggccgctgcaagccgttctcg gcggctgccgacggcaccggctggagcgagggcgtcggcctggtggtggccgagcggctc tccgacgcgctgcgcaacggccaccccgtcctcgccgtgctgaagggctccgccgtcaac caggacggcgcctccaacggtctcaccgctccgaacggcccgtcccagcagcgcgtcatc cgccaggccctggcgaacgccgggctcaccgccgccgacgtcgacgcggtggaggcccac ggcaccggcaccacgctcggcgaccccatcgaggcacatgccctcctcgccacctacggg cagcagcgccccgacgaccggcccgtcctcatcggcgccctcaagtccaacatcggccac acccagtccgcggcgggcatcgccggcgtcatgaagatggtcatggcgatgcggcacgga gagctgcccggcaccctgcacctggacgagcccagcccccacgtcgactgggccgagggc aacgccaggctcctgacggcggccgagccctggcccgagaccgaccggccgcgccgcgcc gccgtctcctccttcggcatcagcggcaccaacgcccacgtcgtcctggaacaggcgccc ccgcgcgagaccgaaccggcacccgccccggccacgaggcccggcgccctgccctggatc ctgtccgcgcggaccggcgacgccctacgggcccaagccgcgcggctcgcccgccatgtc cgtaccctgccccacctcgaaccggccgccgtcgcccactccctcgtgtccgcccggtcc ctcatggagcaccgcgccgccgtcgtcgccgaggaccgggacgcgttcctcgccggcctg gacgccctcgccgaggaccgcaccgccgccggcctggtgaccggcgtcgccgccaaggcg cccctcgccttcctcttctccggccagggctcccagcgccccggcacgggacgcgagctg tacgaggcccaccccgagttcgccaaggcgttcgacgcggtatgcgccgagctcgacccg cacctggagaggcccgtccgcgacgtcgtcctcgcagaggagggcacggccgacgccgcc ctcctcgaccggaccgcgtacacccaggccgcgctcttcgccctggagaccgccctgttc cggctcgtcgagtcctggggcatggcaccgcagttcctcgccggccactccatcggcgag ctcaccgccgcccacgtggcgggcgtcctctccctggaggacgccgcccggctggtcgcc gcgcgcggcaccctcatgcaggcgctgcccgagggcggcgccatggtcgcggtccaggcc accgaggaggagatcctcgcctccctcgccggacacgaggaccacgccgccctcgccgcg gtcaacgggcccgactccacggtcatttcgggcgacgaggagaccgtcgccctgatcgcc gcccggtgggaggagcggggccgccgcaccaagcggctgcgggtgagccacgccttccac tccccgcgcatggacggcatgctggaggacttccgggccgtcgccgagagcctcaccttc cacgccccccgcatccccgtcgtgtccacggtgaccggcgagctcgccaccgccgagcag ctgcgctcgcccgagtactgggtccggcaggtccgcgaagccgtccgcttccacaccgcc gtacgcaccctggcggccgcgggcgtcaccaccttcgtggaggtcggcccccgcggcgtg ctcacccccatggtccaggactccctggccggcctcgaagagcccgtcgccgtccccctc ctgcgcaccggccgccccgagacgcaggccctcgccgaggccgtcgccaccgcctccgcg cacggcgcccgcgtcgactggtccgcctgcctcggcacgcccggcgccacccccgtcgag ctgccgacctaccccttccagcgccagtggtactggctggacccggccggcacgaccggc gagggcccggccaccgaagcgggcgaagccggattctgggaagccgtcgagggggaggac ctggaaggcctgtcggccgtcctcgccctcgacgggaacgaggccgaccagctgggcagc ctcctccccaccctctcggcctggcgcaggctgcgcaggacccaggcgacggcggacggc tggagctaccgcgcgcactggacgcccctcaccacctccaccggccccacggccaccggg aactggctcgtcgtcctgcccgccgcggccaccgacgacccctgggccgcccggctcctc gacaccctccgcgaacagggcctgcgcaccgagtcgttcgtcctgcccgaggccggcggc ttcgagctgccggacgggcccttcgacggcgtcctctccctcctcgccctcgacgaggcc acccacccggacctcccctccgtaccgcgcggcctgaccgccaccaccgccctcctgcgc gccctggagaccgcggacacccgggcaccgctgtggtgcgtgacccgcggcgccgtcgcc gtcgaccggcgggacccgctcaccgcccctgtgcaggcccaggtgtggggcctcggccgg gtggtcgccctggagtccccgcagagctggggcggcctcgtcgacctccccgagaacgtg gacgcccggatcgtctccggtctcctcgacaccctcgcccggggcgaggaccaggtcgcc gtccggcccgccggcaccttcgcccgccgcctggcacgcatcgcgcccggcggcgacacc ggcgccgggtggaccgcccacggcacggtcctcgtcaccggcggcaccggcgcgctgggc gcggagctcgcgcactggctggcggacgccggagcggaacacctcctcctgctcggccgc cggggcctggaagcccccggcgcccgcgaactcgcggccgcgctcgccgaccgcggcacc aaggtcaccgtcaccgcctgcgacgccgcggaccgcgacgccctggccgccgtcctcgcc ggcatccccgaggacctgccgctgaccggtgtcgtccacgccgcgggcgtcctcgacgac ggcgtgctcgacgcgctcacccccgggcacttcgagaccgtcctgcgccccaaggccacc gccgcccgcaacctgcacgagctcacccaggacctcggcctggagatgttcgtgctgtac tcctcggtcgccggcgtcctcggcaacgccggacaggcgaactacgccgcggcgaacgcc ttcctcgacgccctcgccgaacagcggcgcggcgcggggctgcccgccacctccgtcgcc tggggcccctgggccgagcacggcatggccacggacggcgacctcgccgaccggctgagc cgcgacggactgctccccatggccgcgggccccgcactcgccgccctgcgccaggccctc gcccaggacctgacgaccgtgaccgtcgccgacatcgactgggccgcctacgccgccgcc ctcacggccgtccgccccaaccccctcatcggcgacctgcccgaggtccgccgcgccctt gattccggcggccgcccgcgcgagcggcgctccccgctgcgcgaccgcatcggcgccctg ccgcccgccgaacaggaacgggccctcctccagacggtgcgggaggaagccgccaaggtc ctcggtcaccccaccccggacaccgtcgacacccagcgggccttccgcgagatgggcttc gactcactgatggcggtcgagctgcgcaaccgggtctccgcggcggtgggcctccggctg cccgccaccctgctctacgaccaccccagctgcaccgcgatcgccgagtacctgcgcgag gagatcctgggcaccacggggcccgccgcgctcgtggcgccctcggccgccgccctcgac gaacccgtcgtcatcgtcggcatggcctgccgcttccccggcggcgtgaacaccccggac gacctctggcgcctgctgtccgagggcgaggacgcgatctccccgctccccggcgaccgg ggctgggacctcgaccggctctaccaccccgaccccgaccaccagggcacgagctacgcg cgccacggcggcttcctcgacgacgcggcaggcttcgacgcggacttcttcggcatctcg ccgcgcgaggcgctcgccatggacccccagcagcgcctgctcctggagaccacctgggag gccctcgaacacgcgggcatcgacccggagaccctgcggggaagcagcaccggcgtcttc gccggcaccaacgcccaggactaccgcacggttctggacgcggcacgcgacgaggtcgcc ggccacgccctcaccggcaacgccatgagtgtgatctccggccgggtctcctacaccttc ggcttcgagggcccggccgtcacggtcgacacggcctgctcgtcggcgctggtcgccctg cacatggcggtccagtccctgcggtcgggcgagtgctcgctcgccctcgccggcggtgtg acggtgatgtcgtcgccgtccgccttcgtggagttctcccggcagcgcggactggccccc gacggccgctgcaagcccttcgcggcgggcgccgacggcaccggctggagcgaaggcgcc ggcctgctgctcgtggagcggctctccgacgcccgccgcaacggacaccgcgtgctcgcg gtggtgcgcggcacggccgtcaaccaggacggcgcgtcgaacggcctcagcgcccccagc ggcccgtcccagcagcgcgtgatccgccaggccctggccaacgccgacctcaccgcggcc gacatcgacgccgtcgaggcccacggcaccggcaccgccctcggtgaccccatcgaggcc caggccctcctcgccacctacggacaggaccggcccgagggccgccccctcctgctgggt gccgtgaagtccaacctcggacacacccaggccgccgcgggcgcggcgggcgtgatgaag atggtgctggcgatgcgccacggggtgctgccccgcaccctgcacctcgacgagcccacc ccgcacgtcgactggaccgacggcacggtcgagctgctcaccgagcgcaccgaatggccc ggcacgggcctcccgaggcgggccgccgtctccgcgttcggcatcagcggcaccaacgcg cacgtgatcctcgaacagcccgggaccgaagagcccgagaccccggccgacgcccccgag gcaccggccaccgagtccggggacacgctgccgctgctgctgtccggcaggaccgaggag gccctgcgcgcccaggccgagcgcctgctgtcccacctcggcgccgagcccgcaccgcgg ctcacggacgtcgcctggaccctggcgacggcccgcacccgcttcccccaccgcgccgcc gtccaggccggtgaccacgacaccgcggtacgcgccctgaccgccctggccgcgggcgac gccgacgcctccctcgtcacgggcaccgcgcggacgggcaaggacgccgtcctcttctcc ggtcagggttcgcagcgtttggggatgggccgggagctgtacgcccggttccccgtcttc gccgatgctttcgacgcggtgtgcgcggggctggacgagcacctggaccgccccctgcgg gatgtggtgtggggtgaggacgcggagctgctgaaccagaccgcgtacgcgcagacggcc ctgttcgccatcgaggtggcgctgttccggctggtcgaatcgtggaacgtgcggccggag ttcgtggccgggcactccgtcggtgagatcgccgccgcgcacgtcgccggcgtcttctcg ctgaccgacgcctgcgcgctcgtagcggcacgcggccggctcatgcaggccctgccctcg ggcggcgccatggcggcgatccgggccaccgaggacgagatccgcccccacctgaacgac gacgtcaccatcgcggccgtcaacggcccgtcgtcggtcgtggtctccggcacggaggcg gccgtcgaggcggtccgttcccgcttcgaggacgagggcaggaagaccagccgcctccgg gtctcgcacgccttccactcgcccctgatggaccccatgctggacgagttccgcgccgtc gccgagggcctcgcctacggcacgccggagctcaccgtcgtctcgaacgtcaccggcgcc ccggccaccgccgagcagctgtgcgcggccgagtactgggtgacccacgtccgcgaggcc gtacggttcgccgacggcgtccgcgccctccacaccgagggcgtgacgcgcctcctggag ctggggcccgacggcacgctctcggccatggcccgtgagtcgctgccggacgagacggcc accgtgcccgccttgcgcaaggaccgcccggaggagacggcgctcctcaccgctctcgcc cacctgcacgtccagggcgccgtcgccgactgggccgcgttcttcaccggcaccggcgcg cacaccgtcgacctgcccacgtacgccttccagcaccagcggttctggcccacgcccgga ctcaccggccccggggacatcggcgccgccggcctggaagccgccgggcacccgctgctc agcgccgccgtggaactgtccgacagcgacggcctgctgttcaccacccgtctgtccctc cagtcccacccctggctcgccgaccacgtcatcatgggctcggtgctgctgcccggcacg gcgttcgtcgaactcgccgtccgcgccgccgacgaggtgggctgcgaccggatcgacgac ctcaccctggccgcgccgctcgtcctccccgagcacggcggcgtccagctgcaactgcgc gtcggccccgccgacgagtccggcaaccgcaccctcagcgcccgttcccggcccgagggc gacggcgaccgcccgtggacgcggcacgcgaccggcgtcctcgcgacggcggagcgggcc gccgaacccggccatgacttccgggccggaccctggccgcccaccggcgccgagcccgtc gacgtgaccggcctctaccagggcttcgccgacggaggattcgactacggaccccacttc cggggcctgcgggcggcatggcgccgcggcgacgaggtgttcgccgaggtcgccctgccc gaggtcgccgagggtgacgcgcccgcgtacgggctgcacccggccctgctcgacgcggcc ctgcacgtctgcgccttcaacggcgtggaccagggcgtcgtgcccttctcctgggagggc gtctcgctccacgcctccggcgcctcggcggtacgggtacgcgtcgtccggcacggcgcg gacgccgtgtccgtcgacgtcgccgacaccgagggcggaccggtcgccacggtcgacacg ctgaccgtacgggccgtctccgccgaccagctggacggcggcgcgagccccgtggggcgc gacgcgctgttccacgtcacgtggaaccccctgcgcctgcccccggccggcaccgcggag accgtggccacgatcggcaccctccccggcgcaccgttcgacagccacgccgacgtggag tccctggcgggatccggccgggtgccgggcacggtgctggcaccggtgacacccggctcc ggcgacgtggtggagtcggcacacgccacggcggcccgggcgctggacctgatccggtcg tggctggcggacgaccggctcgcggagtcgcggctggtgttcgtcacccgcggcgccgtc tccggcgacgacctcgccgccgccaccgtgtggggcctggtgcgctcggcacagtccgag aaccccggccgcttcggcctggtggacctggagggcgacgccgatgtgacggtgctgccc cgggccctggcctcggacgagccccaactgctcgtacgcggcggcgaggccatggccgcc cggctggcccgcgcgcagacccaggcgcggaacgcccccgcctgggacgcgaccggcacg gtcctgatcaccggcggtacgggcggcctcggccgtgtgatggcccgtcacctggtggag cgcggggtgggcagcctggtgctggtcagccgccgcggcccggccgccgaaggcgccggg gaactggtggccgagctgcgccggaacggcgccgaggcgaccgtggaagcgtgcgacgtg acggaccgcgccgccgtcgccgacctggtggaccggcacggcatcaccgccgtcgtgcac acggccggcgtcctcgacgacggcgtggtgggatccctcaccccggaacggctggcggcc gtcatgcggccgaaggtcgacgccgcgtggaatctccacgaggccaccaaggacctggaa ctcgacgccttcgtcgtcttctcctccgtggcgggcaccataggcagcgcgggacagggc aactacgcggcgggcaacaccttcctcgacgccctggcccaccaccgccgcgcggcgggc ctcccggccgtgtcgctggcgtggggcccctggtcccaggacggcggcatgaccggcacc ctgtcggaagccgacctccagcgcatcgcccgccagggcatgcccgaactcacccccgcc gagggcacggcgctcttcgacgccgcactggccaccgacgccgccctcgtcctccccgta cgcttcgacctggccgagctgcgcgaacaggacgacgtccccactctgctgcgcgggctg atccggacccgtacccgccgctcggccgtcgccggctcggcagcggcctccggcctgctc ggccgcctgtccggactgggtgccgccgaacgccgcgagacgctcctggacctggtacgc gcccaggtcgccgtggtcctcggccacgcgaacccgctgacggtcgacccggcccgggcc ttccaggaactcggcttcgactccctgacggccgtcgaactgcgcaaccgcgtcaacaag gccacgggcctgcgcctttcggccaccgccgtcttcgactacccgacggcggacgcgctg gtcggcttcctgctcgacgagctgttcggcgggcagccggaggagcgggtgccgtccctg gccggcgccccggcggcgaccgccgacgaccccgtcgtcatcgtcggtatgagctgccgc tacccgggcggcgtggcctcgcccgaggacctgtggcgcctggtgtcggacggcgtggac gccgtctccggcttcccggccgaccgcggctgggacatcgagtcgctctacaaccccgac ccggacgccctcggcacctcctacacccgctccggcggattcctccacgaggccggggac ttcgaccccgagttcttcggcatgagcccccgggaggcgctggccacggactcgcagcag cggctcctgctggagtccacctgggaggcgatcgagcgcgcgggcatcgacccggcgacc ctgcgcggcagccggaccggcgtcttcgccggtgtgatgtacaccgactacagcgagatc ctcgtcggcgaccagtacgagggctaccgcggcaacggcagcgccgccagcatcgcctcc ggccgggtgtcgtacaccttcggcttcgagggcccggccgtcacggtcgacaccgcctgc tcctcgtccctggtcgccctgcactgggcggcccaggcgctgcgctccggcgaatgctca ctggccctggcgggcggtgtgacggtgatgtcgacgcccacgacgttcgtggagttctcg cgccagcgcgggctgtccgcggacggccggtgcaaggcgttctccgacgcggccgacggc gtcggctggggcgaaggcgtcggcatgctggtgctggagcgtctgtcggacgcccgccgc aacgggcaccgggtgctggcggtcgtccgcggctccgcggtcaaccaggacggcgcgtcg aacggcctgaccgcgcccaacggcccgtcccagcagcgcgtgatccggcaggccctggcc agcgccgggctgtccgcggcggacgtggacgcggtggaggcgcacggcaccggcaccacg ctgggcgaccccatcgaggcccaggccctgctggccacctacggccaggaccgccccgag gaccgcccgctgctcctgggcacggtgaagtcgaacatcggccacgcgcaggccgcctcc ggcgtcgccggcgtgatcaagatggtcatggcgatgcgccacggcgtcctgcccaggacc ctgcacatcgacgagccgtcgtcgcacgtggactggtcggcgggggccgtggagctcctc accgaaccggccgagtggccggagtccggccgtcgccgcgcgggcgtctcctccttcggc gtcagcggtacgaacgcgcacgtcatcctggaacagccggagccggccgaggcggcggag acggcaccggagcccggcagcgacgtcctgcccgtggtgctctcgggcaggaacgaggcg gccctgcgcggccaggctgcacgcctgctgtcctacgtggccggccacgacgagctgccc gcccgggacatcggctactccctggccgtgggccggtcgagcttcgcccaccgcgcggtg gtgtggggcgtggagcggtgcgacctggtgcgcgccctgtcggccgtcgcggtcggcgag agcggcccgggtgtggtcgcgggggcggtgagtgccggtaagtcggcgttcctgttctcg ggtcagggttcgcagcgtttggggatgggccgggagctgtacgcccggttccccgtcttc gccgatgctttcgacgcggtgtgcgcgggcctggacgagcacctggaccgccccctgcgg gatgtggtgtggggtgaggacgcggagctgctgaaccagaccgcgtacgcgcagacggcc ctgttcgctgttgaggtggcgctgttccggttggtcgaatcgtggggtgtgcggccggag ttcgtggccggtcactcggtcggtgagatcgccgccgcgcacgtggcgggagtcttctcg ctgacggacgcctgcgcgctggtggcggcacgtggtcggctgatgcaggctctgcccacc ggtggtgccatggtcgccgtccaggcggaggaagccgaggtgcttccgctgttgacggag ggggtgtcgatcgctgcggtcaacggtccgtcgtcggtggtggtctccggggccgaggag gccgtggaggcgatccgctcgcacttcgcgggtgaggggcgcaggaccagcaggctgcgg gtctcgcacgccttccactcgcccttgatggagccgatgctggacggcttccgggagatc gtggccgggctgtcgttcggcgagccgaggatcccggtggtctccaacctgacgggccgg ctcgccgagtccgggcaactggcctccgccgactactgggtgcgtcacgtccgcgaagcg gtgcgcttcgcggacgggatgagcgccttggaggcggaaggggtgacgcggttcctggag ctcggccccgacggtgtcctgtctgccatggcccgcgagtcggtgtcggaggacgccgtg ctcacgcccgtcctgcgcaaggaccggcccgaggacacggccgctctggaagccctggcc cagctgtacgtccagggcgtaagggtggactgggcggcgatgttcgccggtacgggtgcc cggcaggtggacctgccgacgtacgcgttccagcacgagcggttctggccctcgggcggg gtggcgcgtgcgggtgatgtgcggttcgcgggtctgggttcggcggagcacccgttgctg ggtgccgcggtcgagctggcaggttccggcgggctgctgttcaccgggcggctgtcggtg tcgtcgcatgcgtggcttgcggatcatgtggtgatgggttcggtgctggtgccgggtacg gcgctggtggagctggccctgcgcgcggccgacgaggtcggctgcgacctgctggaggaa ctgacccttgccgcgccgctggtgctgcccgcctcgggtggcgctgtgcaggtgcaggta tgggtcggtgagcccgacgagtcgggtcgccgctcggtggcggtgcactcccgccagggc gacgaaccgtggaccctgcacgccggtggctcggtgaccaccggggccgagccccagcgg ttcgacaccacgacatggcccccgaagggtgccgagcccgtcgatgtgacgggctgctac gagcagttcgcggaggccggattcctgtacgggccggcgttccaggggctccaggcggct tggaagctcggtgacgacgtgttcgccgaggtccggctccccgaggggacagacggtgcc gcctacggcctgcaccccgccctcttcgacgccgcgctccacgcgtcggcgttcggcggg ggagacgacgcgggcggcgtcccgttctcgtgggccggcgtgtcgctgcacgccgccggc gcctcggagctccgtgtccgtgtccgccgcgtcgagagcgggatgtcgatagcgatggcg gacgcggccggcgcgccggtcgcctcggtggactcgctggccctgcggccggtctccgcc gaccagttgcggaccggcgaccgggactccctcttcacgctcgactgggcacccgtgccg ctcacggacgcacgcgtcgagctcgcgacgggcccggacggagaaccgctccggacgtac acggacctggcgtccctcgccgacggcgaggctcccgaggtcgtgctggtcgcccaggac gccggttccgccggcgccgtggagtccgtgcacaccggcgccgcctgggcgctgggcctg gtgcggtcgtggctggcggacgaccggttcgcggagtcgcggctggtcttcgtgacccgt ggcgcggtctccggtgacgatctcgccggcgcctccgtgtggggcctggtgcggtcggcg cagtcggagagcccgggccggttcggcctggtggacctgggtgacgacgccgatacggcg ctgctgccgcaggcgctcgccacggacgagcctcagcttctgctccgtgacggtcaggcc ctggcggcccggctcgcccgggcggagacgcgagtcaccgctgaggtcacgtgggacacg tccgggacggtcctgatcaccggtggtacgggtggcctcggacgcgtgatggcgcgtcac ctggtggccgagcgcggggtgcggagcctgctgctggtcagccgccgcggcctcgccgcc gagggtgccgaggagctcgtcgcggagctggcggagcagggcgccgacgtgaaggtcgag gcgtgcgatgtgaccgacggggccgctgtggcggacctggtggcacggcactccgtcacc gccgtcgtgcacaccgcgggtgttctggacgacggtgtgatttcctcgctgaccgcggac cggctgtcggccgttctgcggccgaaggtcgacgcggcgtggaacctccacgaggcgacg aaggacctggacctcgacgcgttcgtcgtcttctcctccgtggcaggtacgttcggcagc gccggccaggccaactacgcggccggtaacgccttcctggacgcgctggcccgctaccgc cgtgcccatggccttccggcggcctcgctggcgtggggcccgtggtcccaggacagcggt atgaccggcacgctcaccgaagccgacctccagcggatcgcccgttccgggatgccgccg ctgtcggccgaggaaggcgtcaccctcttcgacgccgccctcgccaccgccgagccgatg ctgctccccgtccgcctcgacctcgcggccctgcgcgcccaaggcgagccccagccgctg ctgcgcggtctgatccggacccgcacccgccgcacgaccgcctccggctcggccgcggcc tccggcctcgtacagcgcctggccgggctgtccgaaggcgagcggcgcgccgtgctgctg gacctggtgcgcgagcggatcgcggccgtcctgggccacgcccggccggagacggtcgac gcgtccaaggccttccaggagctcggcttcgactccctgacggcgatcgaactccgcaac aagctgggcaaggccaccgggctgcggctgtcggcgacggccgtgttcgactacccgacc gccgacgccctggcggaccacctcctcgacgaactgttcggcgcggacaccgaggaactc ctccccgtgcccgccctgccgccgctgacggacgacccggtcgtcatcgtcggcatgagc tgccgctaccccggcggagtcacctccccggaggacctctggcggctggtgtcggacggc gtggacgcggtctccggcttcccggccgaccgcggctgggagatcgaggacacctacgac ccggagcgcgagggcgccatcgccacccgctccggcggattcctccacgacgcggcggag ttcgaccccgagttcttcggcatgagcccccgggaggccctgaccaccgacgcccagcag cgcctgctgctggagaccacctgggaggccctcgaacgcgccggcatggacccggccgcg ctgcgcggcagccgcaccggcgtcttcgccggcgtgatgtaccacgactactcccagctc ctcgccgggcgcgagttcgaggggtaccagggcagcggcagcgcgggcagcgtggcgtcg ggccgggtgtcgtacaccttcggcttcgagggcccggccgtcacggtcgacacggcgtgc tcgtcgtcgctggtggcgctgcacctggccgcgcagtcactgcgctcgggcgagtgctcg ctcgccctcgcgggcggcgtgacggtgatgtcgaccccgctgaccttcgtggagttctcc cgccagggcgggctctccccggacgggcgctgcaaggcgttcgccgacggcgccgacggc gtgggctgggccgagggcgccggcatcctggtgctggaacggctctcggacgcgcgccgg aacggacaccggatcctggcgaccgtgcgcggcagcgccgtgaaccaggacggcgcctcc aacggcctcaccgcccccaacggcccgtcccagcagcgggtgatccggcaggcgctggcc agcggtggcctgtccaccgcggacgtcgacgtcgtcgaggcccacggcaccggcacgacc ctgggcgaccccatcgaggcccaggcgctgctggcgacctacgggcagcaccggccggag gaccgtccgctgctgctcggcacggtgaagtcgaacatcggtcacacacaggccgcggcg ggcgtcgcgggtgtgatcaagatggtgatggcgatgcgccacggcgaactcccgcgcacg ctgcacgtcgacgccccgtcgagccacgtcgactggtcggcgggggccgtggagctgctg accgagccggccgcctggcccgagggggaccggccgcggcgcgcgggcgtgtcctcgttc gggatcagcggcacgaacgcgcacgtgatcctcgaacagcccgagccggagccggccggg cccggggaggagccgtcggacacggaggacctcgtcccgttcgtggtgtccggcaagtcc gcgcccgcgctgcgggcccaggccgcccgtctgctgtcccacctcgcccacgagcccgga cagcggctcacggacgtcgcgtactccctcgcgaccgcccgttcgggcttccaccaccgc gcggtggtgctggccgcggaccgggacgccctgctgcgctcgctgtccgccctggccgag ggccggagcgaggcggacatcgcggcggaaggcgagacccgcgcgggcaagcgtgccttc ctgttctcgggtcagggttcgcagcggctggggatgggccgggagctgtacgcccggttc cccgtcttcgccgacgctttcgacgccgtgtgcgcggggctggacgagcacctggaccgc cccctgcgggatgtggtgtggggtgaggacgcggagctgctgaaccagaccgcgtacgcc cagacggccctgttcgccgtcgaggtggcgctgttccggctcatggaggcgtggggcgtg cgccccgaccacctgatgggtcactcggtcggtgagatcgccgccgcgcacgtcgcggga gtcttctcgctggcggacgcctgcgcgctggtggcggcacggggcaggctgatgcaggcc ctgcccacgggcggcgcgatggcggccatcggggcggcggaggccgaggtccttccgctg ttgacggagggggtgtcgatcgctgcggtcaacggtccgtcgtcggtggtggtctccggg gccgaggaggccgtggaggcgatccgctcgcgcttcgcgggtgagggaaacaggaccagc aggctgcgggtctcgcacgccttccactcgcccttgatggagccgatgctggacgagttc cgggaggtcgccgagcgcgtgacatacggcgtgccgggcatcccggtcgtctccaacgtc accggcgagccggccaccaccggacaactgggctcggccgagtactgggtccgccacgtc cgcgaggccgtacggttcgccgacggcgtccgcgcactggaggcccagggcgtgaccgag ttcctggagctcggccccgacggcgccctctccgcgctcgccgcggactccgcgcaggac ggagccgtcttcgccccggccctgcgcaaggaccgcgccgaggaaccggcgctgctcacg gccctggcacggctgcacgtccagggcgtgccggtcgactgggcggccgtcttcgccggc accggcgcccggcaggtggacctgccgacgtacgccttccagcgggcgcggttctggccc gccgcgaccggcgcccgctccggcgacgtccggtcggcgggtctgggttcggcggagcac ccgctgctgggtgccgcggtcgagctggcggggtccggtgggctgttgttcacgggccgt ctgtcgatgtcgtcgcacccgtggcttgcggatcatgtggtgatgggttcggtgctggtg ccgggtacggcattggtggagctggccctgcgtgcggccgatgaagtgggctgcgacgtg ctggaggagttgacgctcgcggcgccgctggtgctgccggtttccggtggcggtgtgcag gtgcaggtgtgggtcggtgagcccgaggagtcgggtcgccgctcggtggcggtgcactcg cgtgagggtgacgaaccgtggacgctgcacgcgagcggtgccctgaccagtggtgccgaa ccggtggcgttcgacacctcggtctggcctccgaagggtgccgagtccgtcgatgtggcg ggctgctacgagcggttcgcggacgccgggttcgcctacggcccggtgttccagggcctc caggcggtctggaagctcggtgacgacgtcttcgccgaggtccggctccccgagggcacg gacggtgcggcctatggtctgcacccggccctcttcgacgccgcactgcacgcgtcgatg gccgccgggggagagaccgaaggcgccgtcccgttctcgtggaccggcgtgtcgctgcac gcctccggtgcctcgcacatccgcgtccgtatccgtgacgtcgacggcggagcgtcgctc gcgatcgtggacccggcgggcgcgcccgtcgcctcggtcgagtcgctcgtcgtacgtccg gtctccgcggaccagctgcggaccggcgaccgggactccctcttcacgctcgactggacc ggagtccagctcaccggtgagcccctcgggtcgctcgccgtactgggggaggacaccgag cacctcttgaaggagctccggctccagacccacgcggatctggaagccctcgccgggaac ggcgttcccgacgtcgtgctcgtcccggcgtccgcgggttccgccggcacagtggagtcc gtgcacgcggcgactgcccgggcgttgggtctggtgcggtcgtggctggcggacgagcgg ttcgcggagtcgcggctggtgttcgtgacccgtggcgccgtttccggtgacgacctcgcg ggtgccgctgtgcgcggtctggtgcggtcggcgcagtcggagagcccgggccggttcgtt ctggtggatctggagggtgacgccgatgtgagggtgctgtctcgggcactggccaccgat gagcctcagctgctgatccgtgacggtcaggttctcgcggcccggctcgcccgggcggag acgcggagcacggcggatgtcgtctgggacgcttccggcacggttctgatcaccggtggt acaggtggtctcggtcgtgtgatggcgcgtcacctggtggcggagcacggagtgcggagc ctgctgctggtcagccgtcgaggtccggccgccgaaggcgccgaggccctcgtcgccgag ctcgccggccagggcgccgacgtgaccgtcgaggcgtgtgatgtcaccgaccgggccgct gtggcggacctggtggcgcgccactccctcaccgccgtcgtgcacaccgccggcattctc gacgacggtgtcgtcgcgtcgctgaccgcggaccggctcgccgccgttctgcggccgaag gtcgacgccgcgtggaacctccacgaagcgaccgaggagctggacctcgacgcgttcgtc gtcttctcctccgtcgccggtacgttcggcagcgcggggcaggccaactacgccgcgggc aacgcgttcctcgacgccctggcccaccaccgccgggcacgagggctgaccgcggtgtcc ctggcatggggcccgtggtcccaggacggcggtatgaccggcaccctgtcggacgccgac atccagcgcatggcccgttccgggatgccgccgctgtcggccggagagggggcggcactg ttcgacgccgccctcgccgccaccgggcccatggtgctcccggtgcgtctggacctcgcg gccctgcgcgctcagggcgagccccagccgctgctgcgcggtctgatccgtacccgtacc cggcgtacgtcggcgtccggttcggctgtcgcgtccggcctcgtacagcgcttgaccgga ctgtccacggcggaccggcgtgaggtgctgctggacgtcgtacgcgggaagatcgcggcg gtcctcggacacgccggatccgccgagatcgacccgacccgggcgttccaggacctcggc ttcgattccctgacggccgtcgagctgcgcaaccggctcaacgacgtgaccggcctgcgt ctcccggccacggccgtgttcgactacccgacggcggacgccatggtgggcctgctgctg gacgaactgttcggcgcggagcccgtggtgtcgtcgccggtccgggtaccggccgtcgtc acggacgatcctgtggtgatcgtagggatgagctgccgcttccccggcggagtcacctcc ccggaggacctgtggcggctggtgtcggacggcgtggacgcggtctccggcttcccggcc gatcgcggctgggacgtggaggcgctctacaaccccgaccccgagcacacggggacgagc tacacccgcgcgggcggattcctcaaggaggcggcggagttcgacccctcgttcttcggg atgagcccccgggaggcgctggcgacggactcgcagcagcgactgctcctggagaccacc tgggaggcgctcgaacgcgccggcatcgacccggccgcactccgtggcagccagaccggt gtcttcgcgggcgtgatgtacaacgactacgcgaacctcgtctccggacccgagttcgag ggtcaccagggcagtggcagcgcgggcagtgtggcgtcgggccgggtgtcgtacaccttc ggtttcgagggcccggccgtcacggtcgacacggcgtgctcgtcgtcgctggtggcgctg cacctggccgcgcagtcgctgcggtcgggcgagagctcactggccctggcgggcggtgtg acggtgatgtcgacgccgacgacgttcgtggagttctcccgccagcgcggtctctccccg gacggccggtgcaaggcgttcgccgacggcgccgacggcgtcggctggggcgagggcgtg ggcatgctcgtcctggagcgtctgtcggacgcgcgccggaacggacaccggatcctggcg acggtgcgaggcagcgccgtgaaccaggacggtgcctccaacggcctcacggcgcccaac ggcccgtcgcagcagcgggtgatccgtcaggcgctggcgagcgccggtctgtcgacggcg gacgtggacgcggtggaggcgcacggcacgggcaccacgctgggcgacccgatcgaggcc caggccctgctggccacctacggtcaggaccgccccgaggaccgtccgctgctcctgggc tcggtgaagtcgaacatcggtcacgcgcaggccgcggcgggcgtcgcgggtgtgatcaag atggtgatggcgatgcgccacggtgagctcccgcgcaccctgcacgtggacgcgccgtcg tcgcacgtggactggtcggccggagctgtggagctcctcaccgagccgaccgcctggccg gagggctccggaccgcggcgcgccggtgtctcctcgttcgggatcagcggtacgaacgcg catgtgatccttgagcagcccgctcgggccgaggagcctcaggccggcgcggacacggac gggctcgtgccgttggtggtgtccgcgaagtccccgaccgcgctgcgggcccaggccgca cggctgctctcccgtctcgacgccgaccccgggctgcgggccgcggatctggcctactcg ctggtgacggcccggtcgagcttcgggcaccgcgcggtggtgtggggcgccggccgacag gatgtactgcggtccctgtccgcactggccgtcggtgagacgggtacgggtgtggtcgcg ggtgccgtgggcgccgggaagtcggcgttcctgttctcgggtcagggttcgcagcgtttg gggatgggcggggagctgtacgcccggttccctgtcttcgcggaggctttcgacgcggtg tgcgcgggcctggacgagcatctggagcgcccgctgcgggatgtggtgtggggtgaggac gcggagctgctgaaccggaccgcgtacgcgcagacggccctgttcgctgttgaggtggcg ctgttccggttggtcgaatcgtggggtgtgcggccggagttcgttgccggtcactccgtc ggtgagatcgccgccgcgcacgtcgccggcgtcttctcgctgaccgacgcctgcgcgctc gtagcggcacgtggccggctgatgcaggccctgcccaccggtggtgccatggtcgccgtc caggcggaggaagccgaggtgcttccgctgctgacggagggggtgtcgatcgcggcggtc aacggtccgtcgtcggtggtcgtctcgggcgcggaagaggctgtccttgccgtcgtggcg cacttcgagaacgaaggcaggaagtcgagcaggctgcgggtctcgcacgcgttccactcg ccgttgatggagccgatgctggacggcttccgggaggtcgtggccgggctgtcgttcggc gagccgaggatcccggtggtttccaacctgacgggccggctcgccgagcctgagcagttg gcctccgccgactactgggtgcgtcacgtgcgcgaagcggtgcgcttcgcggacggggtt cagaccctgagcgcggaaggcgtgacgcggttcctggagctcggccccgacggcgtcctc tcggccatggcccgggaatccctgcctgaggcgactgctcctgttcccctcctgcgcaag aaccgggacgaggaggcagccgtattcggtgccttggccgagctgtatgtccagggcgta agggtggactgggcggcgatgttcgccggtacgggtgcccggcaggtggacctgccgacg tacgcgttccagcacgagcggttctggccttcgggcggggtggcgcgtgcgggtgatgtg cggttcgcgggtctgggttcggcggagcacccgctgctgggtgccgcggtcgagctggca ggttccggcgggctgctgttcaccgggcggctgtcggtgtcgtcgcatgcgtggcttgcg gatcatgtggtgatgggttcggtgctggtgccgggtacggcgctggtggagctggccctg cgcgcggccgacgaggtcggctgtgacgtgctggaggagttgacgctcgcggcgccgctg gtgctgccggtttccggtggcggtgtgcaggtgcaggtgtgggtcggtgagcccgaggag tcgggtcgccgctcggtggcggtgcactcgcgtgagggtgacgaaccgtggaccctgcac gcgagcggtgccctgaccagtggtgccgaaccggtggcgttcgacacctcggtctggcct ccgaagggtgccgagtccgtcgacgtggcgggctgctacgagcggttcgcggacgccggg ttcgcctacggcccggtgttccagggcctccaggcggcttggaagctcggtgacgacgtg ttcgccgaggtccggctccccgagggtacggacggtgcggcctacggcctgcaccccgcc ctcttcgacgccgcgttgcacgcgtcgatggccgccgggggagacggcgcgggcgccgtc ccgttctcgtggaccggcgtgtcgctccatgcctccggtgcctcgcaggtccgggtgcgc ctgagcctcgccgagggcggtgtgtcgatcgcgatggccgacccggcgggtgcgccggtc gcctccgtggactcgctcgtcgtgcgtccgatctccgccgatcagctgcgggccggtgac cgggactccctcttcaccctcgactgggcccgtgtcgagctcaccggtgagcccctcgga tcgctcgccgtactcggcgaggacgccgagggcctgctgaacggactctccctgccggtc cacacggatctggacgccttgaccggggcggacgtccccgaggccgtactcgtcgcgcag cgcctcgacgccggcgacaccgtggaggccgtgcacgtggcgaccgcccgggcgctggat ctggtgcgggcgtggctggcggacgagcgtttcgcggagtcgcggctggtgttcgtgacc cgtggcgcgacgtccggcgagaacctcgccggcgccgcggtccaagggctgatccgctcc gcgcagtcggagaaccccggccgcttcggcctggtggacctggacggcgacggcgatgcc gcggtggaggtgaaggcgcttccccaggccctcgcttccgacgagccgcgactgctgctc cgtgacggccaggccctcgcggcccgtctcgcccgagtggagacacagggcatcgccgat gtcacgtgggacgcttccggcacggtcctgatcaccggtggtacgggtggcctgggccgg atcctcgctcgtcacctggtgacggtgcacggggtgcggagcctgctcctggtcagccgc agcggcctcgccgcccaaggagccgaggagctcgtcgccgagctcgccgggcagggcgcc gacgtgaaggtcgaggcgtgcgacgtgaccgacggggccgctgtggcggacctggtggca cgccactccgtcaccgccgtcgtgcacaccgccggcgtcctcgacgacggtgtgatcgcg tcgctgaccgcggaccggctcgccgccgttctgcggccgaaggtcgacgccgcgtggaac ctccacgaagcgacgaaggacctggacctcgacgcgttcgtcgtcttctcctccgtcgcc ggtacgttcggcagcgccggccaggccaactacgcggccggtaacgccttcctggacgcc ctggcccaccaccgccgggcggcgggccttcccgccgtgtccctggcgtggggcccctgg gcccaggacggcggcatgaccggcaccctcacggacgccgacctccagcggatcgcccgt tcgggcatgcccgagctgtcggcggaggagggcgtcgccctcttcgacaccgccgtggcc ggcgccgagccgatgctgctccccgtccgcctggacctcgcggccttgcgcgcccaagga gagcctctgccgctgctgcgcggtctgatccggacccgtacccggcgcacgaccgcgtcc ggtacggccgcggcgtccggcctcgtgcagcgtctgaccgggctgtcctcggccgaggcg cgcgaggtcgtgctggagaccgtacgtggccaggtcgcggccgtactgggccatgacgga gccgcggagatcgacccggaccaggccttccaggacctcgggttcgactccctgacggcg atcgagctccgcaaccggctgagcaccctcgccgaggtccggctgccggcgacgctcctc ttcgactacccgacgccggcggagctcgtcgaccacctcctcacccggatcgcacccgag tcggcctccggcccggaagcgctcctgagcgagctcgacaggctggagaaggcgttcggt ggacttgacgtcactgaggaggcccacgagcagatagcgggccgcctggaggtgctcatg gcgaagtggggcgccctgcgggacgccggcgcgggagccgaccgtgaagccgcctcggac gacgaggacttcgacttcgactcggcctccgacgacgaggtcttcgacctcctcgacaac gagctcggactgtcctga

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