Streptomyces noursei NK660: DC74_5690
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Entry
DC74_5690 CDS
T03082
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
salu
Streptomyces noursei NK660
Pathway
salu00470
D-Amino acid metabolism
salu00550
Peptidoglycan biosynthesis
salu01100
Metabolic pathways
salu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
salu00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
DC74_5690
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DC74_5690
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DC74_5690
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
salu01011
]
DC74_5690
Enzymes [BR:
salu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
DC74_5690
Peptidoglycan biosynthesis and degradation proteins [BR:
salu01011
]
Precursor biosynthesis
Amino acid ligase
DC74_5690
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AIA06142
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Position
6496922..6498058
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AA seq
378 aa
AA seq
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MSSETSSHKPRVAVVFGGRSSEHAISVVTAGAVLAAIDRDKYDVLPIGITTDGRWALTAD
DPARMAITDRRLPSVAELAEGGDGAVVLSADPTTREVVYTEPGAVPKALGEVDVVFPVLH
GPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKDYMKRVFTSFGLPVGPYEVVRPREWD
TDPAAARKKIVDFAGEHGWPLFVKPARAGSSMGISKVDDLAGLDAAIEEARRHDPKIIVE
SLLRGREIECGVLEFEDGPRASVPAEIPPVTAHDFYDFEAKYIDSAAGIVPAPLTDEQTA
EVRALAVAAFDAASCEGLVRADFFLQDNGEFVINEINTLPGFTPISMYPRMWQESGVSYP
ELVDRLLEAALRRSTGLR
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagacctcctcccacaagccccgcgtcgccgtcgtgttcggcggccgcagc
tccgagcacgccatctcggtggtcaccgccggagccgtgctggccgccatcgaccgcgac
aagtacgacgtgctgcccatcggcatcacgaccgacggccggtgggcgctgaccgccgac
gaccccgcgcggatggcgatcacggaccggaggctgcccagcgtcgccgagctcgccgag
ggcggggacggcgcggtggtgctctccgcggaccccaccacccgcgaggtcgtctacacc
gagccgggcgcggtccccaaggccctcggcgaggtcgacgtcgtcttcccggtgctgcac
ggcccgtacggcgaggacggcacgctccagggcctgctggaactgtccggggtgccctac
gtcggctccggcgtgctcgcctcggccgtgggccaggacaaggactacatgaagcgggtg
ttcacctccttcgggctgccggtcggcccctacgaggtcgtccgcccgcgcgagtgggac
acggaccccgcggccgcccgcaagaagatcgtggacttcgccggtgagcacggctggccg
ctgttcgtgaagcccgcccgggccggttcgtccatgggcatcagcaaggtcgacgacctc
gccgggctggacgcggccatcgaggaggcccggcgccacgaccccaagatcatcgtggag
tcgctgctgcgcggccgcgagatcgagtgcggggtgctggagttcgaggacggcccgcgg
gccagcgtccccgccgagatcccgccggtcaccgcccacgacttctacgacttcgaggcc
aagtacatcgactcggccgccggcatcgtgcccgcgccgctgaccgacgagcagaccgcc
gaggtccgggcgctggcggtcgcggccttcgacgcggcgtcctgcgagggcctggtccgc
gcggacttcttcctgcaggacaacggcgagttcgtgatcaacgagatcaacacgctgccc
ggcttcacgcccatctcgatgtacccgcggatgtggcaggagagcggcgtcagctacccg
gaactcgtcgaccggctcctggaggcggcgctgcgccgctcgacggggttgcgctga
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