Syntrophus aciditrophicus: SYN_00412
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Entry
SYN_00412 CDS
T00346
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sat
Syntrophus aciditrophicus
Pathway
sat00470
D-Amino acid metabolism
sat00550
Peptidoglycan biosynthesis
sat01100
Metabolic pathways
sat01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sat00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SYN_00412
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SYN_00412
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SYN_00412
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sat01011
]
SYN_00412
Enzymes [BR:
sat01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SYN_00412
Peptidoglycan biosynthesis and degradation proteins [BR:
sat01011
]
Precursor biosynthesis
Amino acid ligase
SYN_00412
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Gene cluster
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Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
RimK
CPSase_L_D2
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
ABC76865
UniProt:
Q2LS09
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All DBs
Position
1023515..1024582
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AA seq
355 aa
AA seq
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MESQNETKLRVGIIMAGLSSEKEVSLESGRNIFSKIDRRKYSPIPIFMDSDAALWEIPLK
LLMRNCTRDVEEDLAEEAVRVPYEELKTRVDLVFLALHGKYGEDGCMQGLLELLKIPYTG
SGVLASALGMDKLASRRVLEINGIDVPRTVPVFRGAWKPEEENALFERIEQEIGFPCVVK
PSREGCSTGVKKVMSRAGLSDALNGAFLWDCTALVEEFIDGMEVTCGILGGNPPTALTPS
ETIATSDVLSLEDKFLYGQGENKTPARLPGETLMKIQEVAVKAFEALDLKGYARIDMFVT
SAGRVLVLEPNTQPGMTPSTVLFHQAAASGITQTGLVDRILEAALSVHAGKKGPL
NT seq
1068 nt
NT seq
+upstream
nt +downstream
nt
ttggaaagtcaaaatgagacaaaattgcgcgtaggcatcatcatggccgggttgtcctct
gaaaaagaggtgtccctggagagtgggcggaatatcttcagcaagattgaccgccggaag
tacagccccatccccatcttcatggacagcgatgccgccctgtgggaaatacccctcaag
ctgctgatgagaaactgcacccgtgatgtcgaagaggatctcgccgaagaggccgtgcgg
gttccttatgaagagctcaaaacccgggttgatctcgtttttcttgctctgcacggcaag
tatggcgaggatggctgcatgcaggggttgctggagcttttgaaaatcccctatacaggc
tccggcgttcttgcctctgcgctgggaatggataagcttgccagccggcgggtcctggag
atcaacggaatcgatgttccccggacggtcccggttttccgcggcgcatggaaaccggag
gaggagaatgccctttttgagcggatcgaacaggaaatcggttttccctgcgtcgtcaaa
ccctctcgggaaggatgcagcacgggcgtgaagaaggtaatgtcccgggcagggctttcc
gatgccctcaacggtgcttttctctgggattgcacggccctggtggaggaattcatcgac
ggcatggaagtgacctgcggcattctgggcggcaatccgccaacggctttgaccccgtcg
gaaaccatcgccacatctgatgtgctttcgctggaggataaatttctctatggtcagggg
gaaaacaagaccccggcccgccttcccggggaaaccctgatgaagattcaggaggtggcc
gtaaaggcctttgaagcccttgatctgaagggttacgcccggatcgatatgtttgtcaca
tccgccggccgggttctagtgctcgaacccaacacccagccgggaatgacgccgtccacc
gttctcttccatcaggccgccgcatcgggaataacccagaccggactggttgaccgaatt
ctggaggcggctctttccgttcacgccggcaaaaaaggaccgctgtaa
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