Staphylococcus aureus subsp. aureus CN1 (CA-MRSA): SAKOR_02048
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Entry
SAKOR_02048 CDS
T02826
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
saun
Staphylococcus aureus subsp. aureus CN1 (CA-MRSA)
Pathway
saun00470
D-Amino acid metabolism
saun00550
Peptidoglycan biosynthesis
saun01100
Metabolic pathways
saun01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
saun00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SAKOR_02048
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SAKOR_02048
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SAKOR_02048
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
saun01011
]
SAKOR_02048
Enzymes [BR:
saun01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SAKOR_02048
Peptidoglycan biosynthesis and degradation proteins [BR:
saun01011
]
Precursor biosynthesis
Amino acid ligase
SAKOR_02048
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AGU62188
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Position
complement(2092407..2093588)
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AA seq
393 aa
AA seq
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MILLRFKDANKSINNRTKSILIYIKVANPDISLEENEMTKENICIVFGGKSAEHEVSILT
AQNVLNAIDKDKYHVDIIYITNDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESS
SGQPYDAVFPLLHGPNGEDGTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLP
QLPYISFLRSEYEKYEHNILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEA
FQFDRKLVIEQGVNAREIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPA
DLDEDVQLTLRNMALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLW
ENMGLSYPELITKLIELAKERHQDKQKNKYKID
NT seq
1182 nt
NT seq
+upstream
nt +downstream
nt
gtgatactattaagattcaaagatgcgaataaatcaattaacaataggactaaatcaata
ttaatttatattaaggtagcaaaccctgatatatcattggaggaaaacgaaatgacaaaa
gaaaatatttgtatcgtttttggagggaaaagtgcagaacacgaagtatcgattctgaca
gcacaaaatgtattaaatgcaatagataaagacaaatatcatgttgatatcatttatatt
accaatgatggtgattggagaaagcaaaataatattacagctgaaattaaatctactgat
gagcttcatttagagaatggagaggcgcttgagatttcacagctattgaaagaaagtagt
tcaggacaaccatacgatgcagtattcccattattacatggtcctaatggtgaagatggc
acgattcaaggactttttgaagttttggatgtaccatatgtaggaaatggtgtattgtca
gctgcaagttctatggacaaacttgtaatgaaacaattatttgaacatcgagggttacca
cagttaccttatattagtttcttacgttctgaatatgaaaaatatgaacataacatttta
aaattagtaaatgataaattaaattacccagtctttgttaaacctgctaacttagggtca
agtgtaggtatcagtaaatgtaataatgaagcggaacttaaagaaggtattaaagaagca
ttccaatttgaccgtaagcttgttatagaacaaggcgttaacgcacgtgaaattgaagta
gcagttttaggaaatgactatcctgaagcgacatggccaggtgaagtcgtaaaagatgtc
gcgttttacgattacaaatcaaaatataaagatggtaaggttcaattacaaattccagct
gacttagacgaagatgttcaattaacgcttagaaatatggcattagaggcattcaaagcg
acagattgttctggtttagtccgtgctgatttctttgtaacagaagacaaccaaatatat
attaatgaaacaaatgcaatgcctggatttacggctttcagtatgtatccaaagttatgg
gaaaatatgggcttatcttatccagaattgattacaaaacttatcgagcttgctaaagaa
cgtcaccaggataaacagaaaaataaatacaaaattgactaa
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