Streptomyces caniscabiei: IHE65_12415
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Entry
IHE65_12415 CDS
T08931
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
scae
Streptomyces caniscabiei
Pathway
scae00470
D-Amino acid metabolism
scae00550
Peptidoglycan biosynthesis
scae01100
Metabolic pathways
scae01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scae00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
IHE65_12415
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
IHE65_12415
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
IHE65_12415
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
scae01011
]
IHE65_12415
Enzymes [BR:
scae01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
IHE65_12415
Peptidoglycan biosynthesis and degradation proteins [BR:
scae01011
]
Precursor biosynthesis
Amino acid ligase
IHE65_12415
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
WEO23916
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All DBs
Position
complement(2850783..2851940)
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AA seq
385 aa
AA seq
DB search
MSSENLPQSPEQPSRKPRVAVVFGGRSSEHGISVVTAGAVLRAIDRTKYDVLPIGITRDG
RWALTADEPERMAITDRRTPSVEELAESREGGVILPVDPANREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLKVGPYVV
IRPREWQLDESAARKKIIDLAGEHGWPLFVKPARAGSSIGITKVDDLDGLDEAIAEAQRH
DPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPPEAHAYYDFEAKYIDSTPGIVPAP
LTPAETAEVQRLAVDAFDAASCEGLVRADFFLTEDGDFVINEINTLPGFTPISMYPAMWK
ASGVEYGELVDRLIQAALHRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagagccctgagcagccgtcccgcaagccgcgcgtggcc
gtcgtcttcggcggccgcagctcggaacacgggatctccgtggtcacggccggcgccgta
ctgcgtgccatcgaccggacgaagtacgacgtcctgccgatcggcatcacgcgggacggc
cgttgggcgctcaccgccgacgaaccggagcggatggcgatcaccgaccgccgtacgccg
agcgtcgaggaactcgccgagtcccgggagggcggcgtgatcctgcccgtcgaccccgcc
aaccgcgaagtcgtctacagcgagcccggttcggtgcccaaggccctcggcgaggtcgac
gtcgtcttccccgtcctgcacggcccctacggcgaggacggcaccctccagggcctcctg
gagctctccggcgtcccgtacgtcggctcgggcgtcctcgcctcggccgtcggccaggac
aaggagtacatgaagcgggtgttcacgtcgttcgggctcaaggtcggcccgtacgtggtg
atccgaccgcgcgagtggcagctcgacgagtccgccgcccgcaagaagatcatcgacctc
gccggtgagcacggctggcccctcttcgtgaagcccgcccgcgcgggctcctccatcggc
atcaccaaggtcgacgacctcgacggcctcgacgaggcgatcgccgaggcccagcggcac
gacccgaagatcctggtcgaggcggccctgcgcggccgggagatcgagtgcggcgtcctg
gagttcgaggacggcccgcgcgcctccgtccccgccgagatcccgccgcccgaggcccac
gcgtactacgacttcgaggccaagtacatcgactcgacccccggcatcgtcccggccccg
ctgacgccggcggagacggccgaggtccagcggctcgcggtcgacgccttcgatgcggcc
tcctgcgagggtctggtccgcgccgacttcttcctcacggaggacggcgacttcgtgatc
aacgagatcaacacgctccccggcttcacgccgatctcgatgtacccggcgatgtggaag
gcgagcggcgtcgagtacggcgagctggtggaccgcctgatccaggccgcgctgcaccgc
tcgacgggcctgcgctga
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