Siniperca chuatsi (mandarin fish): 122873520 Help Entry 122873520         CDS       T08948                                  Symbol pkd1a Name (RefSeq) polycystin-1 isoform X1   KO K04985   polycystin 1 Organism schu  Siniperca chuatsi (mandarin fish) Brite KEGG Orthology (KO) [BR:schu00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:schu03037]     122873520 (pkd1a)    04812 Cytoskeleton proteins [BR:schu04812]     122873520 (pkd1a)    04040 Ion channels [BR:schu04040]     122873520 (pkd1a)    04091 Lectins [BR:schu04091]     122873520 (pkd1a) Cilium and associated proteins [BR:schu03037]  Primary cilia and associated proteins   Other primary cilia associated proteins    122873520 (pkd1a) Cytoskeleton proteins [BR:schu04812]  Eukaryotic cytoskeleton proteins   Intermediate filaments    Intermediate filament-binding proteins     122873520 (pkd1a) Ion channels [BR:schu04040]  Voltage-gated cation channels   Transient receptor potential channel (TRP)    122873520 (pkd1a) Lectins [BR:schu04091]  C-Type lectins   Group 10: Polycystin    122873520 (pkd1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PKD REJ PKD_4 PLAT Polycystin_dom PKD_channel LRR_8 Lectin_C LRR_4 WSC GPS Motif Other DBs NCBI-GeneID:  122873520 NCBI-ProteinID:  XP_044046236 LinkDB All DBs Position LG3:23893083..23957365 Genome browser AA seq 4695 aa AA seqDB search MPCGNGQTLSKRKHGVCIPRFSFFSSLLVALCCLEAWGSGPQGDGGRSCSPCPVNCSCAL AGPQPSCVVNCSNIGLEKAPAAADIPLATNVLDLSKNHIPSLDTSLLDRLTGLRELYLQG NRINVLPRGVFCCGPLSILDLSNNQITTIEERICDNLCNLTQIDLSSNPFECDCKLFRLV SWLQEKGVRVRRPDAMLCKHPPELRHQPLLNVSLLTCGLNYAACLEDSSSGGGGRSELVI FSSSTPGNFTREQCNSVCYAASHRYGGLGARHECLCSTNSEPNFISESQCSAACTNPNVM KECGWTVAHDVFAVDFSVSLKPLPLQSVHDSISFSAASSVTPVTLSWDFGDLSSRVNTTG TGLTTATHKYGLPGHYAVSLMAWAGHKEVSAHVEVTVTLPSRLELRCPSLAVASKSLEFT LVSWGAAGVDVDWKITKDGVQVAKASPHCPKDGVYHAESSRCFQIVPVELSWTDARQQCS DRGGDLAIVRSDALRNLLAHKVTQPRERGVWLGLSDVNSPGKLRWVNGSEAQEGEEGLPP RSPISRGNVCVSLDQRNQTSSHQCNAKRAYVCQYSPQVRVPDAGIYMVGLAVFPSHNPLQ HAPSAPLSSPQPPSVGIEVLLFPALSFVHAGRLSSLEFVTQELSSQIHVRFQTYRPHCHY PGLHLLLPSCGGPACAPVAVCVHNDTRSSDPPSCPRLEQWCPFQRRCLPLSSPCQPSSCP NCTQAHRLPPGVLRPRYTLQNEVVFTLPAGPAAHILVQEQLEDLLVSRGDVIALQHDAGP ASLLPCQSSPHSLWRQSVLALNQSEWFWINNTRQSTDSSADHDADPLPDPELDVKALVED GEGGWLEEVVCPVRVLYVGHSKTQLQGAQLSAGLPQPGLYSLLVTSAEPSYPASASCPLR VVPPLGLTILHPPTRNGTLYLQPNDTRLLLRVHSRYMTKASRRGSNCSVTFQPDCPPEFS SSPALCRPGPSSGSGIEVTEPSLYAVLDLSLGTEEQRSPVQVELEAHNNVTEASLSVVVQ LEAPLRGLVVQPHPAHRVLMESVVSYTSSVLEGSNPTFKWTVDDKPYFTYYNTVLNVIYQ HAAVYKLTVTAMNHVSTLTEHFNVTVDRLQPMANLTVKGVPDVVPQGSTQTLTTSVLVDM SVSATFRWSFGDGGYKEFEYKPQYPPSLLCPESPNQVLLSNNVTYIYSQPGIYTALVSVS NRYENISQSINMSVYSILTRVDIQTEPRLLLTGKSADFEAHPLPSPYGIHYDWHFGDGSA PLQGRRVAHTYAQSGVFNVCVSVNNTISSTEVCAEMFVYEEIEDLTAESSSPTELHSPTT VWARLASGNNITWTFSMGDGTIYTTSEPHVSHSFIKDGNFTVNVTAANAVSSGWTILPVQ VFVFQVVRMEPSGCVQERTPVNFQAWVSGNTSAHLYEWSFGDGSPNETHHGNPRVSHTYW TSGNYHLSLLLSSGVNKATKANFFNWVCVQPALTIISLTHEKSHYAVGEEIRFQARAEPE FNYSYQWDFGREEDVLLIRGSGNIVTTYKNPGYYMVTVIVFNNISTSNTSVVIEVLMHIG PVVIHHNGTKYNNLTLREPYAFITSSLASNVTYVWNFGDGNVLTGQNILHTYNISGNYNI TLTAANTVSRNQTTLPVAVLAPICGLTVNASLVNVPLNASVHFEAQMEEGDGVRFSWILC DRCTPILGTHTMFYTFRSVGTFNIIVTAENDVGTAQASIFLFVQRELEGLQILAVEEIGG GGGTGLDGCCFATNRVLHLQAGLKEGTNMTFTWNLIRELDAVSSSFNISGKTVEVNFSTP GPCNIFLQAANLLGQLSVNRTIHFLEPVGGVHLQISDNPVAANASTNLTVLTIEGSDLQY RWSVNGDALQWNKPWNSHTFISAGLKQVSVEVFNEVSSEVVSKIVSVQEVISGLRFTATN VTEQSYVATGVSVLLQGEVLTGTNVTWTWLLNGRTETGRKTSLIFQEPKTAIVTLNATND VSGQVVSREIFVQDKIQGLELRASKNIVAVGEKVEFTISMAAGSDVCLILSISGDATVIP QPNQTYVHTFSRVDMYMVNLTAHNQVSFKRRHLQVEVMEPVRGLSILGSCAAITVGVKRL FVANILTGKPVSFLWTFDVDHLHHVSLMGKEVSYTPGVAGLLTIYLKAFNALHDQNITKH ILVQNLLTSADLYAAPRDTFINKTVTLMASITPNHTKSNPVECLWDFGDGSTPVNTNTTT VGYEYRHPGHYLVQVNCSNLVSWVLAQVEVNISVLECEEPEVQVVQAPRLAIWRSQSTLV EASVDLKGCLRYGAQYLWQILSTPSCDNDRDHRIPSGVVTQPSQSLLVPVIRLPVEVDVQ RLQLSLPKMALAAGNYTVVFSLSYKGVPLRKAACLQLSVMAARLMPIIEGGTYRVWSRTQ DLQLSAEQSYDPNMDPDSQSLLHYHWECQSTSKGAEHCSSLNFGLGSSGPVLGISGSELE AGVEYTFRLTISKDGMAPESTTQTVLVQSGHIPMVYLECVSCKAQSIYEVSQNSYVYLRG TCTNCQGFHRGRWSAMTLQNETLVLDSSSTTTGSDGMNLVLRQGVLRYKDSYIFTLHVTD SSLDGEGAASITLHHNMAPAGGECQLRVGGEAGVEYRDGDVEGWRIRTLLDRVHFTCSGY SDLGVSETPLLYSLLVTRCREDYCEDFCVYKGSSPEHSAFLPPGFSSAQHRVAVSITVED HQGAASIAFNKSIEVVPPDPPPEYNSLPHWLSELTESKLKKLLEQGDSQRVRELSLALIT VLNEYEQTRESVRVSRDERSYRVRVRSNITRALTALDLTTVNDIQQTSAALAQCTAVSRE FICEECQNSTLNKLESMLEILQTDTKQGTVTPTEIADNILNIMGDLIHQVSQSASQSYLQ PAYMDSPSPPFTSSFPSSGEEQGGPLLDPSPSSLEPHPLRVAAKAYSLSSVLMLILMHAR VLNEEPLVLRGAEIAATGKLADPQSLLCYHGNNSPECQRFSIPRAFNNSLGKAAAGNSIM QLLFQVDSNPFPFNYVANYTVSTEVASMEFRTENGTQIPISGLDDSLAITVAINNGSSGA EAGPEGSGTGGVPTAGAVNISHCDSVIVRVSTGNTNRQAGLFVQLNFTSLEDATEKDKRV EDVEEPYITAYLHLHERPNEFNCTDKKRIKLRMTRGQDLDHRKYTFFLSPESYDTTLDYF INVSTACSPGSQPVGVHLEVGVFASLCQYFSETEKQWRTDGMVPLAETNASRAVCRTRHL TAFAAGLFVPANAISFKVPERSGDSSLVVLLVCVLGLLSYVVAAAILHKLDQLDLRRAGV VPLCGQDGLFKYEIQVKTGWSRGAGTTAHVGISLYGRESRSGHRHLDSRGAFTRNTLDIF HIATDTSLGSVWKIRIWHDNKGLSPAWMLQYVLVKDLQTGSSYYFLVEEWLSVDNERTDG RVEIEVEASEEAVLRQLPRLLRCELQRALCESHLWLSLWERPPRSPFTRLQRATCCAVLL QLFVLANTLWYSIVVDKRYSPQAVSRFASLNGETAAAGVVTCLIVYPLYLLVFTLFRMSR SKCVSVEQVPPQVDQESVEIDDFLDNSMAGSSFLFFNGETNSEETNVDLPTPSTKSVESW GMAEEEMEDRDWPELLSDVSVVGGAGHGAGLPRLKRGQGSRHLGVDMTFNPDDEEGTDQR NKYFTSSDEDLIKHILTDGQNFFPQADESEMADLSSIFGDKTEVILLQKLNEPLPLESVR RDPPKTAFTSNTVVTDVCRPRRFPPWCGRAALWGSWAGITLASGVSIWAAHGFSQSVAMM WLISCFASFLCSCLLLEPIKVLCEAVYYAVCVLRLRPEDQDVLVEFPRVERVVQRVPRVR PPQGFALSQARHQARKVHMLHTMLKNFLVYMFFLLVVLLLNYSDSAKDTHSLRLRTQLQR ALHTPEYHNINSRDDILMWLNESLLPRLLDDSALLRDTGSVLLGTLRLRQIRDTQVAGGS RVGDSILGKSWVTSPTEDAENYTALGASDKNWLWRLGQMGVYNSRDVVQLNRSQEEASSS LQQLQQLHWLDYRTRAVFVEFSLYNINTNLLAVFSFLFEFPVSERAQSSLDLLVTTLWPI TGLDLQLLLMMVLLALVVYFLVRGILGFLREGYVYLLSAWRLLGICKLALAASVCGLHLT RCTMATQQWASYLKQPKDAFTDFYPLARQSQIYTVMSALLLFILVLKASHQLRFLREWAV FGRALRRSVWELLGVALALLLLVLAYSHTGHLLFYSVLDGYGSVSSACLSLLGAGGRGLL SWHPSWTTTGPSSTVSSLVFHASFAILRLVLLWLVTSVLLRNYRRARAELYRPAVDLQDY EMVELFLRRLKMWMGLSRTKEFRHKVRFEGMELPPSRSSSTSDCKSLCLPPLDSPDSPPT PDSIDAGSEASWRPASSSPCSLTEAPGIGLGLGLGLGLGLGPGVVMGSTSWRERAETEAS LRRLLPTLDALLQQLDRVTMATEDLYHIECRLERAQRKRRRRGRERGGGGQGGRSEAGQR GKGEDKDSAGWRERKSGKEKHKGSKKGKKTNKGELPKDCGKTVANPKKTAVATPVPFLKP RPASATTHTPAHHSSAKPSASAPPPTPFTDKSASDSPPVSSANTHPSHVPLPKTPTAPPC TPAPTPSLPSTPAPTPISRDWDPPTERETLSSSSLFNHPAHTTTIPTRKRKRKPPPLKNK VHPNLDRHGPGHPKS NT seq 14088 nt NT seq  +upstreamnt  +downstreamnt atgccttgtggaaatggacagactttatccaagcgaaaacatggcgtctgcatcccgagg tttagcttcttttccagtctgcttgtggcgctctgctgcctggaggcatggggctccggg ccgcagggggacggcggcaggagttgcagcccctgtcccgttaactgcagctgcgcgctg gcggggccccagccgtcctgcgtcgtcaactgctccaacatcgggctggagaaggcccca gcagcggcagacatcccgctagccaccaacgtgctagatctttccaagaaccacatcccc tcccttgataccagcctgctagatcgtctcactggcctccgagagctgtatcttcaaggg aacaggatcaatgttctccccagaggagtattctgctgtgggccgctgtcaatcctcgat ttaagcaacaaccaaatcaccaccatagaagaaagaatatgcgacaacctatgcaattta actcaaattgacctgagcagtaaccccttcgagtgtgactgtaagctgttccggctggtc agttggctccaggagaaaggggtgcgagttcgacgcccggacgccatgctctgcaagcac cctcctgagctccgccaccaacccctgctcaacgtgagcctgctcacctgtggtctgaac tatgcagcttgtcttgaggacagcagcagtggaggagggggacggagcgagcttgttatc ttctcttcctccacacccggaaacttcacacgtgaacagtgtaacagtgtgtgttacgct gcatcacaccgctacgggggcttgggggcgaggcacgagtgtctctgcagcacaaactca gagccgaacttcatcagcgaatctcagtgctccgctgcctgtacaaaccccaatgttatg aaggagtgtgggtggactgtggctcatgatgtgtttgcggtggacttctcggtctcactg aagcctctcccactgcaaagtgttcacgacagcatcagtttctctgccgcctcctctgtc actccggtgacactgtcctgggactttggtgacctttcatctcgggtcaacactacagga acagggcttaccacagcaactcacaaatatggacttccgggacattatgcggttagtttg atggcctgggctggacacaaggaggtctctgcacacgtagaagtgaccgtgacacttcca tccaggctggagctgcgctgtccatctcttgctgtggccagtaagagcctagagttcacg cttgtcagctggggcgctgctggcgtggatgtagactggaagatcacaaaggatggcgtc caagttgccaaagcctcgcctcactgtccaaaggatggggtgtaccacgccgagtcttca cgctgtttccagattgttccagtggagttgagctggacagatgctcgacaacagtgttca gaccgcggcggggatctggcaatagtcaggagtgacgcgctgcgtaacctgctggcacac aaagtcacacagcccagggagcgaggtgtgtggctgggcttgagtgatgtcaactctcca ggcaagctgcgctgggtaaacggctcagaggcacaggagggagaggagggcctgccacct cgttccccgatctcccgcggaaacgtgtgcgtgtcccttgatcagcgcaatcagaccagt tcacaccaatgcaacgccaagcgggcctatgtctgccagtacagcccccaagtgcgagtt ccagatgcagggatctacatggtgggcctggctgtgtttccctcccataatcctttgcaa cacgccccatccgctccgctctcttctccacaacctcccagcgttggcatagaagtgctg ttgttcccagctctgagctttgttcatgcaggtcgtctgtcctccctagagtttgtcact caggagctcagctcacaaatccacgttcgattccagacctacagacctcactgtcattat cccggcctgcacctgctgctacccagttgtggaggtccagcgtgtgctccggtggctgtt tgtgtccacaatgacaccaggagcagtgatccaccctcttgcccccgactagagcagtgg tgtcccttccaacgccgttgcctgcccctctctagtccctgccagccatcttcctgtcct aactgcacccaggctcaccgcctgccccctggggtgctgaggcctcgatacaccctacag aatgaggtggtcttcactttaccagcaggaccagctgcacacatactggtacaagaacaa ctggaggacctcttggtttcccgtggtgatgtcatcgccctgcagcatgatgctggcccc gcctcccttcttccctgccaatcctccccacactcactgtggcgacaatctgttttagcc ctcaaccaatcagagtggttctggatcaacaacaccagacagtcaacagactcctcggct gaccacgacgctgaccctctgcctgacccggagcttgacgtgaaggcgctggtggaggat ggtgagggaggctggctggaggaagtagtttgccccgtcagagttctctatgtgggacac agtaagactcagctgcagggagcacagctgtctgctggtctaccccagcccggactgtac agccttctggtgacttcagctgagccatcatacccagcctcagcatcatgcccgttgcgg gtggtacctcctctgggcttgacaatcctccacccccctacccggaatggcaccctctac ctgcaacccaacgacacccggctgctgctccgtgtccactctcgctacatgacaaaggcc tctcgacgtggtagtaattgcagtgtgacgttccagcccgactgtcccccagagttttct tccagcccagcgctctgtcgtcccgggccgagctcagggtcagggattgaggtcacggag cccagcctgtatgcagtgctggatctgagcttggggacggaggagcaaaggagtccagtg caggtggagctggaagcccataataatgtgacggaggccagcctgtcagtggtcgtccag ctggaagcgccactcagaggactggtggtgcagccacaccctgcacacagggtgcttatg gagtcagtcgtgagctacacatcatcagtgcttgaaggttccaatcccacatttaaatgg acagtggatgacaagccctacttcacctattacaacactgtcctcaatgtcatctaccag cacgctgctgtctacaagctcacagtgacggccatgaaccatgtcagcaccctcacagag catttcaacgtgaccgtggaccggctgcagcccatggccaacctcacagtaaagggtgtg ccagatgtggtccctcagggctccactcaaactctcaccacctctgtgctcgtcgacatg tctgtgtccgccactttccgatggtcttttggtgacggtggatataaggagtttgaatac aagcctcagtaccccccctccctcctttgtcctgagtcgcccaatcaggtcctcctaagc aacaatgtcacctatatctactctcagccaggaatatacacagcgctggtgtcagtgtcc aatcgttatgaaaacatcagtcagagcatcaacatgagcgtctacagcatcctcactcgt gttgatatacaaacagagccgcgactcctcctcactggcaaatcagccgattttgaggct caccctctgccctcaccctatggcattcactatgactggcactttggagatggttctgcc ccactgcaaggtcgccgcgtggcacacacctatgcacagagtggagtctttaatgtctgt gtatcggtaaacaacaccatcagttctacggaggtttgtgccgagatgtttgtatatgag gagattgaagatttaacagctgaaagctcctctcctacagagcttcacagtcctactaca gtatgggcacgacttgcatcaggtaataacatcacatggacattctccatgggcgatggg accatctacacaacatctgaacctcacgtgtcacacagctttatcaaagatggcaacttt acagtgaatgtgactgccgcaaatgcagtgagctctggctggacaatcctaccagtgcag gtgtttgtcttccaagttgtgaggatggagccgtccgggtgtgtccaagagcggacccct gtcaacttccaggcctgggtgtctggtaacacatcggctcatctttatgaatggagcttc ggggatggaagccccaacgagacacaccatggcaaccccagagtctcacacacctactgg acaagtgggaactaccacctctctctgcttctttccagcggggtaaacaaagccaccaag gccaacttcttcaactgggtgtgtgtgcagccagctttaaccattatcagccttacccat gagaaatcacactacgctgttggggaggaaatacggttccaggccagagctgagccagaa tttaactacagctatcagtgggattttggtagagaggaagacgttttgcttattcgtggt tctgggaatatcgtgacaacgtataaaaacccaggttattacatggtgacagtcattgtc ttcaataacatctccaccagtaacaccagtgttgtgattgaggttctgatgcacatagga ccagttgttattcatcataatggcactaagtacaataacctgacccttagagaaccatat gctttcataacatcttccttggcttccaatgtcacttacgtctggaactttggagatgga aatgtgcttacgggccagaatatcctccacacctacaacatctcgggaaactacaatatt acactgacagcagccaacacagttagcaggaatcaaactactttacctgttgctgtgctt gcaccaatctgtgggttgaccgtcaacgccagcttggtaaatgtccctctcaatgcctca gtacactttgaggcccaaatggaggagggagatggtgtccggttctcttggatcttgtgt gaccgctgcaccccaatcctagggacccacaccatgttctacaccttccgctctgttggc actttcaatatcattgtgacagcggagaacgacgtgggaacggcacaagcaagtatcttc ctgtttgtccaacgtgagttggagggtctgcagattttagcagtggaggagatcggagga ggtggaggcacgggattggacggctgctgctttgctacaaaccgtgttctccaccttcaa gcaggattaaaggaaggaaccaacatgacgtttacttggaacctcatcagagagctagac gccgtcagctcaagttttaacataagcgggaagacagtggaggtgaatttctccacacca ggtccatgtaacatctttctccaggcagccaacctcctgggccagctgtccgtcaacaga accatccacttcctggaaccagtcggaggggtgcacctgcagatcagcgacaacccagtt gcagccaatgcttcaactaacctgacagtattgactattgaaggctcggatctgcagtac cgctggtctgttaatggggatgctctgcagtggaacaagccctggaacagccacaccttc atcagtgctggcctaaagcaagttagtgtggaggtcttcaatgaagttagctcagaggtt gtgtcaaagattgtcagtgtccaggaagtcatttcggggctaaggttcacagctaccaat gtgacagagcagagttacgtagcaacaggcgtcagcgtcttgctgcagggggaggtactg acaggaaccaatgtgacgtggacatggctgctgaacggaagaacagaaacaggaaggaaa acttctctgattttccaggagccaaaaacagccatcgttactttgaatgccaccaatgat gtcagtgggcaagtggtttccagagagatctttgttcaggacaagattcaagggttggag ctgagagcaagtaaaaatattgtagcagtcggtgagaaggtggagttcaccatttctatg gcagcgggctcggacgtttgtctcatcctcagcatcagtggagatgccactgttatccct caacccaaccaaacctacgtccacacattcagcagggtggacatgtacatggtgaatctc actgctcacaaccaggtgagtttcaagaggcggcacctccaggtcgaggtgatggagccg gtgcgtggactttccatccttggaagctgcgcagcaatcactgtaggtgtaaagagattg tttgtggccaacatcctgacgggcaaacctgttagtttcctgtggacttttgatgtggac cacctccaccatgtatcacttatgggcaaagaggtgtcctacacgccaggagtagcaggt ttattgaccatctacctgaaggcctttaacgcactgcatgatcagaacatcaccaagcac atcctggtgcagaacctgctgacgtctgccgacctgtatgcagcgcctcgggacactttc atcaataagactgtgaccctgatggcctctattacacccaaccacaccaaatctaatcct gtggagtgcttgtgggactttggggatggttctactccagttaacaccaacaccacaact gtgggttatgagtacagacacccaggacactacctggtccaggtgaactgcagtaaccta gtgagctgggtgttggctcaggtagaggtaaacatcagtgtattagagtgtgaggagcca gaggtgcaggtggttcaagccccccgcctggccatctggcgctcccagtccacattggtg gaggccagtgtggacctgaaaggctgcctacgctacggagctcagtacctctggcagata ctctcaacaccctcctgtgataatgacagagaccaccgtattccctctggggtggtgact cagccctctcagtctttacttgtcccagtaattcgcctgccagtggaggtggatgtgcag cgactacagctgtcgttgcctaagatggctctggcagcagggaactacaccgtggtgttt tctctgtcatacaaaggcgtgccgctaaggaaggctgcctgtctccagctcagcgtcatg gctgccaggctgatgcccatcatagaagggggcacctacagggtgtggtcaaggacacag gacctgcagctcagtgcggagcagtcctatgaccccaacatggacccagacagccagtca ctacttcactaccactgggagtgtcaaagcacttcgaagggtgcagagcactgctccagt ctgaactttggactgggctccagcggtccggtgctgggaatctccggctccgagctggag gcgggcgtcgaatacactttcagactgaccatcagcaaagacggcatggcaccagagtcc acaacacagactgtgcttgtccagagtggccatattcccatggtgtatctggagtgtgtg tcctgtaaggcccagtccatctacgaggtcagccagaactcgtatgtctacctcagagga acctgcaccaactgccagggctttcatcgtgggcgttggagtgccatgacgctacagaac gagactctggtcctagactcctcttccaccaccacaggaagtgacggcatgaatctggtg ctgcggcagggcgtcctgcgctacaaagactcctacatcttcacactgcacgtgactgac agcagtctggatggcgagggcgccgcctccatcactctgcatcacaatatggccccagct ggcggggagtgtcagctgagagtgggaggggaagcgggagtggagtaccgggacggagac gttgaaggctggaggatacgcacactgttggaccgggtgcacttcacctgctcaggctac agtgatctaggggtctcagagactcctttgctctacagtctactagtgacgcgctgcaga gaagactactgcgaggacttctgtgtgtacaaaggcagcagcccggagcactctgccttc ctgcccccaggcttcagctcagcccaacaccgtgtagctgtatccattacagtggaggac caccagggagctgccagcattgcattcaacaagtccatcgaggttgtgccgccagatcca ccccctgagtacaacagccttccccattggctgtctgagctgacagagagcaaactcaaa aagctgttggagcagggagactcacagagggtccgagagttatcgttggctcttattaca gtcctaaatgagtacgaacagaccagggagtcggtgcgggtgtcccgagatgagcgcagt taccgagtcagagttcgcagcaacatcaccagagctctgaccgctctagacctgaccact gttaacgacatccagcagacctccgctgctttggctcagtgcacggcggtgagtcgagag tttatctgtgaagagtgtcagaacagcactctgaacaagctggagtccatgcttgagata ctgcaaactgacaccaagcagggcactgtcacaccgactgagatagctgacaacatcctg aacatcatgggtgatctgatccatcaggtcagccagtcagcatcccagtcttacctccag cctgcctacatggattccccctcgccccccttcacctcctcttttccctcctctggtgag gagcaaggaggcccgctgttagacccctctccctcctcacttgagccacaccctctgcga gtggcggccaaggcctacagcctgtcctcggttctcatgctgattctcatgcacgcccgt gtgctcaacgaggagccacttgtgctgaggggagctgagatcgctgccacgggaaagcta gcagacccccagagcctgctctgctaccatggcaacaacagtccagagtgccagcggttc tccatcccccgagctttcaacaacagtcttggcaaagctgctgctggaaacagcatcatg cagcttctgtttcaggtggattccaaccccttccccttcaactatgtggcgaactatacc gtctctaccgaggtggcatccatggagttccgcactgaaaatggcacccagattcccatc tccggactggatgatagtctagccatcactgttgccattaacaacggaagtagtggagca gaagcaggtcctgagggttctggtaccggaggggtccccacagctggagctgttaacatc agccactgcgactccgtcatcgtcagggtcagcacgggaaacaccaacagacaggcgggg ctgtttgtgcagctcaacttcacctccctggaggatgccacagagaaggataaaagagta gaggacgtggaggagccatacatcacagcctaccttcatttacatgaaagacccaatgag ttcaactgcacagacaaaaaacgtattaaactccgtatgaccagggggcaagatcttgac cacaggaaatacaccttcttcttgtcgccagagtcgtacgacaccactctggactacttt atcaacgtgagcacggcctgtagccccggctctcagcctgtgggtgttcatctggaggtc ggggtgtttgcctctctgtgtcagtacttcagcgagactgagaagcagtggcggacagat ggcatggtgcccctggcagagaccaacgccagcagagctgtttgtcgcaccaggcacctc acggccttcgctgcaggcctgtttgtaccggccaacgccatcagctttaaagtgccggag cgttctggtgattccagcctggttgtgctgttggtgtgcgtgttaggcttactaagctat gttgtggcagcagccatcttgcacaagttggaccagctggatctccgccgggctggtgtg gttccactctgcggccaagacggactctttaagtacgagatccaggtcaaaactggttgg agccgaggggcaggcaccacggctcatgtaggaatcagtctgtatggacgtgagagccgc agcggacaccgccatctagacagcagaggagctttcacgcgcaacactctcgacatcttt catattgccacagataccagcctgggcagtgtctggaaaatacgaatttggcatgacaac aagggtctgtccccagcatggatgctacagtacgtcttggtcaaagacttgcagacaggt agtagctactacttcctggttgaggagtggctatcagtcgacaatgagagaactgacgga cgggtagagattgaggtggaggcctcggaggaggctgtgcttcgtcagctgccccgcctc ctgcggtgtgagctgcagagggcgttgtgtgagagtcacctgtggctgtcgctgtgggag agacccccccgcagcccattcacccgcctgcagagagccacatgctgcgctgtgttactg cagctctttgtattggccaacacactgtggtatagcattgtggtggacaaaagatacagc ccgcaggccgtgtcgaggtttgcttcattaaatggagagacggcagcagcaggtgtggtg acctgtctgatcgtctaccctctctacctgctcgtcttcacgctcttcagaatgagccgc agcaagtgcgtgtctgtggagcaggtgccaccacaagtggaccaggagtcagtggagatt gatgacttcctggacaactccatggctggaagttccttcctcttttttaatggcgagacc aactctgaagaaaccaatgtggatttgcccactccatcaaccaaaagtgtggagagttgg ggcatggcagaggaggagatggaggacagggattggccagagctgttgagtgatgtgtct gtggtgggaggggcggggcatggggcagggctgccaaggctgaagaggggtcaggggagc cgtcacctgggcgtcgacatgacctttaaccctgacgacgaggagggaactgaccaacga aacaaatatttcacttcctcagatgaggatctgatcaaacacatcctgacagatggacag aacttctttcctcaggcagatgaaagtgagatggctgacctgtcgagcatttttggagat aagactgaagtgattctcctccagaagctgaatgagcctcttcctctagaatctgtgaga agagacccaccaaaaactgctttcacctcaaatacagttgtgacagacgtgtgtcgtccc agacggtttcctccctggtgtggacgtgccgccctgtggggcagctgggcagggatcact ctggccagtggtgtttcaatttgggcggcccatgggttcagtcaaagtgtggccatgatg tggctcatctcctgttttgccagtttcctgtgctcctgcctgctgttggagccaattaag gtgttgtgtgaggcagtttactatgcagtgtgtgtgcttcgtctgcgtccagaggaccag gatgtgctggtggagttcccccgggtggagagagtggttcaacgggtccccagggtgaga cccccacagggctttgctctgtctcaggctcgacaccaggctcgcaaggtccacatgcta cacaccatgctgaagaatttcctggtttacatgtttttcctgttggtggttttgcttctc aactactctgactcggccaaagacacacacagcctgagactgcgcactcagctgcagcga gcactacacacacctgagtaccacaacatcaacagccgagatgacattctgatgtggctg aatgagtccctgttgccacggctactggatgactccgccctcttgagagacacaggaagt gtgttacttggcacgctgaggctccgtcaaatccgtgacacacaggttgcaggtggttcc agggtaggagacagtattttgggaaagagctgggttacatctccaactgaagacgctgag aattacactgctcttggagctagtgataaaaactggttgtggcgtttgggtcagatgggg gtgtataacagcagagatgtggtccagctgaacagaagccaggaggaggcctcttcctcc ttacagcagctgcagcagctgcactggctcgactacaggacccgtgctgtgtttgtggag ttctcgctctacaacatcaacacaaacctcctggctgtcttctccttcctgtttgagttt ccagtttctgagcgagcccagtccagccttgacctccttgtcaccactctgtggccaatc acaggcctggacctgcagctccttctaatgatggtcctcctcgccctggtggtgtatttc ctggtgagggggatcttgggattcctcagagaaggctatgtgtacttgctgtcggcctgg agactcctgggcatctgtaaactggctctggcagcgtctgtgtgtgggctgcacctgacc cgctgcactatggccacgcagcagtgggcgtcatacctgaagcagccaaaggacgccttc acagacttctaccccctggccagacagagtcagatatacacagtcatgtctgccttgctg ttgttcatactggtgctcaaggcatcccaccagttgcggtttctcagagagtgggccgtg ttcggcagagctctgcggcgctcagtctgggagctgctgggcgtcgccctggcattactg ctgttggtgctggcttactcacacacaggacacctgctcttctactctgtattggacggc tacggcagtgtgagctctgcttgtctgtctttgttgggtgctggtggacgtggtctgcta tcatggcatcctagctggacgactaccggcccctctagcaccgtctcctcgctggtgttc cacgcaagcttcgccatacttcggctggtgttgctatggttggttacttctgtgttgctg aggaactaccggcgtgcacgagcagagctgtaccgtccagctgtggatctccaagactac gagatggttgagctgtttctcagacgactcaaaatgtggatgggactcagcaggaccaag gagtttcgtcataaggtgcgttttgagggcatggagctgccaccgtcccgttcgtcctcc accagcgactgtaagtccctgtgcttgcctccgctggacagtcctgactcccctcccaca ccagacagcattgatgcgggctctgaggcctcgtggcgcccggcctcctccagcccctgc agtctgacagaagctccggggatcggcctgggactcgggctgggcctgggtttggggctc ggtccaggagtggtgatgggaagtaccagctggagggagagagcagagactgaagcctct ctgaggaggctcctccccaccctggacgccctgctgcaacagcttgaccgtgtcaccatg gcaacagaggatctgtaccacatcgagtgtagactggagcgagcccagaggaaaaggagg cgtagagggagagagagaggaggtggtggtcagggagggaggagcgaggcaggacagaga gggaagggggaggacaaggactccgctggatggagagaacgaaagagtggcaaagaaaaa cacaaagggagcaaaaaggggaaaaagacaaataagggtgaacttccaaaggactgtgga aaaactgttgccaaccccaaaaagactgcagtagccacacctgttccctttttaaagccc agaccagcctctgccactacacatacccccgctcatcactcatcagccaaaccttcagcc agcgcacctccgcctacaccattcacagataaatctgcctctgactctccccccgtctct tcagcaaacactcatccttcccacgtcccactgcccaaaacacccactgcacctccatgt acccctgcacctaccccttccttgccatctactcccgcgcctacacccattagccgggac tgggacccccccacagagagagagaccctctcctcctccagcctgttcaaccacccagct cacactaccaccattcctacacgcaagcgaaaacgcaaacccccacccctcaaaaacaag gtacaccccaacctcgacaggcatggccctggacaccccaaatcctga

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