Streptomyces coeruleorubidus: CP976_30740
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Entry
CP976_30740 CDS
T07302
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
scoe
Streptomyces coeruleorubidus
Pathway
scoe00470
D-Amino acid metabolism
scoe00550
Peptidoglycan biosynthesis
scoe01100
Metabolic pathways
scoe01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
scoe00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
CP976_30740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
CP976_30740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
CP976_30740
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
scoe01011
]
CP976_30740
Enzymes [BR:
scoe01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
CP976_30740
Peptidoglycan biosynthesis and degradation proteins [BR:
scoe01011
]
Precursor biosynthesis
Amino acid ligase
CP976_30740
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
QEV28055
UniProt:
A0A5J6IHA0
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All DBs
Position
6616043..6617200
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AA seq
385 aa
AA seq
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MSTENLPQSPEQPSRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTKYDVLPIGITQDG
RWALTADEPERMAIIDRRQPSVDLLAESGEGGVILPVDPASREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLKVGPYLV
IRPREWQQDEPAARKKIVDFAGEHGWPLFVKPARAGSSIGITKVDGLSGLDEAIAEAQRH
DPKILVEAALRGREIECGVLEFEDGPRASAPAEIPSPDAHAYYDFEAKYIDSTPGIVPAP
LTPEETAEVQRLAVDAFEAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPQMWQ
ASGVSYPELVDRLVQAALRRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaacctcccccagagccccgagcagccgtctcgtaagccgcgtgtggcc
gtcgtgttcggcgggcgcagctccgaacacgggatctccgtggtcaccgccggcgccgtc
ctcaaggccatcgaccggacgaagtacgacgtcctgccgatcggcatcacccaggacggc
cgctgggcgctcacggcggacgaaccggagcggatggcgatcatcgaccggcgccagccg
agcgtcgacctgctcgccgagtccggcgagggcggagtgatcctcccggtcgaccccgcc
agccgcgaagtcgtctacagcgagccgggatcggtccccaaggcgctcggcgaggtcgac
gtggtcttcccggtgctgcacggcccctacggcgaggacggcacactccagggcctcctg
gagctctccggcgtcccgtacgtgggctcgggcgtgctcgcctcggccgtgggccaggac
aaggagtacatgaagcgggtgttcacctcgttcgggctgaaggtgggcccgtacctggtg
atccggccccgtgagtggcagcaggacgagccggccgcccgcaagaagatcgtcgacttc
gccggggagcacggctggcccctgttcgtgaagcccgcgcgcgccggttcgtcgatcggc
atcaccaaggtcgacggcctctccggcctcgacgaggcgatcgccgaggcccagcggcac
gacccgaagatcctcgtggaggccgcgctgcgcggccgcgagatcgagtgcggcgtcctg
gagttcgaggacggcccccgggcctccgcccccgccgagatcccctcgccggatgcgcac
gcgtactacgacttcgaggccaagtacatcgactccacgccggggatcgtgccggcgccc
ctgacgcccgaggagacggccgaggtccagcgcctggcggtcgacgccttcgaggcggcc
tcctgcgagggcctggtccgcgcggacttcttcctcaccgaggacggcgagttcgtgatc
aacgagatcaacacgatgcccggcttcacgcccatctcgatgtatccgcagatgtggcag
gcgagcggagtgagctacccggagctggtggaccggctggtgcaggcggcgctgcgccgt
tcaacaggccttcgctag
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