Streptomyces cyaneogriseus: TU94_22050
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Entry
TU94_22050 CDS
T03687
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scw
Streptomyces cyaneogriseus
Pathway
scw00020
Citrate cycle (TCA cycle)
scw00630
Glyoxylate and dicarboxylate metabolism
scw00785
Lipoic acid metabolism
scw01100
Metabolic pathways
scw01110
Biosynthesis of secondary metabolites
scw01120
Microbial metabolism in diverse environments
scw01200
Carbon metabolism
scw01210
2-Oxocarboxylic acid metabolism
Module
scw_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scw_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
TU94_22050 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
TU94_22050 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TU94_22050 (kgd)
Enzymes [BR:
scw01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
TU94_22050 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
TU94_22050 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
TU94_22050 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
TU94_22050 (kgd)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AJP03765
UniProt:
A0A0C5G555
LinkDB
All DBs
Position
complement(5167899..5171708)
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AA seq
1269 aa
AA seq
DB search
MSPQSPSNSSSPTTDTDRAGKNPAAAFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYK
PGAAAAQAASGAAATGAAETTAPARPAAPAPQAPAPAAQVPAPAPAAPEKPAAAPAPAAQ
PAAKPAAAAAKPAAAPQPKAAPAKAPAEGPELVTLRGPAAAVAKNMDASLEMPTATSVRA
VPVKLLFDNRIVINNHLKRARGGKISFTHIIGYAMVQAIKAMPSMNWSYGLKDGKPTLIK
PEHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRAREGKLTMDDFTG
VTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGAMDYPAEFQGTSQDTLNKLGISKVMTLTS
TYDHRVIQGAASGEFLRVVANLLLGENGFYDDIFEALRIPYEPVRWLKDIDASHDDDVTK
AARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVGGFAGKSM
MKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHAKPEREEQLRILRRLNAA
EAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRGRLNVLANI
VGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANPSHLEAVD
PVLEGVARAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHI
VINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEACVRVARLAFEFRQAFNKD
VVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQ
DYQGQLEKVFTEVREATSQPSAVEPSDPQAEFPVAVNTAVTTETVKRIAESQVNIPDHIT
VHPRLLPQLQRRATMVEDGTIDWGMGETLAFGSLLLEGVPVRLAGQDSQRGTFGQRHAVI
IDRNTGEEYTPLQYLSEEQARLNVYNSLLSEYAAMGFEYGYSLARPDALVLWEAQFGDFV
NGAQTVVDEFISSAEQKWGQTSGVVLLLPHGYEGQGPDHSSARPERFLQLCAQNNMTVAM
PTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAASKAEEFTTGQFRPVIGDASVDA
AAVKKVVFCSGKVYYDLDAERKKRGVTDTAIIRIERLYPLPGAELQAEIAKYPNAEKYLW
AQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQE
QLVREVFEA
NT seq
3810 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagctcccccacgaccgacaccgaccgggcgggc
aagaaccccgccgccgcgttcggtgccaacgagtggctcgtcgacgagatctatcagcag
tacctccaggacccgaactccgtggaccgagcctggtgggacttcttcgccgactacaag
ccgggggcggccgccgcccaggctgcgtcgggtgccgcggccacgggggccgcggagacc
accgccccggcccggcccgccgccccggccccccaggccccggctccggccgcgcaggtc
ccggcgccggcccccgccgccccggagaagcccgccgcggccccggcccccgccgcgcag
ccggccgccaagcccgccgccgcggccgcgaagcccgcggccgcgccgcagccgaaggcc
gcgcccgccaaggcgcccgccgagggtcccgagctggtgaccctgcgtggtcccgccgcg
gccgtcgcgaagaacatggacgcctcgctggagatgccgacggccacctcggtccgcgcc
gtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctcaagcgcgcc
cgcggcgggaagatctccttcacgcacatcatcgggtacgcgatggtgcaggccatcaag
gccatgccgtccatgaactggtcgtacggcctcaaggacggcaagccgaccctgatcaag
ccggagcacgtcaacctcggtctcgccatcgacctggtcaagcccaacggcgaccgccag
ctcgtcgtcgcggcgatcaagaaggccgagacgctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgccgcgcccgcgagggcaagctcacgatggacgacttcaccggt
gtgacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtcccgcgcctg
atgcccggccagtcggtgatcatgggcgtcggcgccatggactacccggccgagttccag
ggcaccagccaggacacgctcaacaagctgggcatctccaaggtcatgaccctgacgtcg
acctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgcgtcgtcgcc
aacctgctgctcggcgagaacggcttctacgacgacatcttcgaggcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgccagccacgacgacgacgtcaccaag
gccgcccgcgtcttcgagctgatccactcctaccgggtccgcggccacgtcatggccgac
accgacccgctggagtaccagcagcgcaagcaccccgacctggacatcaccgagcacggg
ctcaccctgtgggacctggagcgcgagttcgccgtcggcggtttcgccggcaagtcgatg
atgaagctgcgcgacatcctcggcgtgctgcgcgactcgtactgccgcaccaccggcatc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcgtggagcgc
ccgcacgccaagcccgagcgcgaggagcagctgcgcatcctgcgccggctgaacgcggcg
gaggcgttcgagaccttcctccagacgaagtacgtcggccagaagcgcttctcgctggag
ggcggcgagtccgtcatcccgctgctggacgcggtgctggactcggcggccgagtcccgt
ctggacgaggtcgtcgtcggcatggcccaccgcggccggctgaacgtgctggccaacatc
gtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggcgacgtgaagtaccacctgggcgccgagggcaccttcaccggcctg
gacggcgagcagatcaaggtctccctggtcgcgaacccctcccacctggaggccgtcgac
ccggtcctggagggcgtcgcccgcgccaagcaggacatcatcaacaagggcggcacggac
ttcaccgtcctgccggtggcgatccacggcgacgcggccttcgcgggccagggcgtggtg
gccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatc
gtcatcaacaaccaggtcggcttcaccgcggccccggagtcctcgcgctcctccatgtac
gccaccgacgtggcgcgcatgatcgaggccccgatcttccacgtcaacggcgacgacccg
gaggcgtgcgtccgcgtggcgcggctggccttcgagttccgccaggccttcaacaaggac
gtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcc
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtac
accgagtccctcatcggtcgcggcgacatcaccctggaagaggccgagcaggcccttcag
gactaccagggccagctcgagaaggtcttcaccgaggtccgcgaggccacctcgcagccc
tccgcggtggagccctccgacccgcaggccgagttcccggtcgccgtgaacaccgcggtg
accacggagaccgtcaagcggatcgccgagtcccaggtcaacatccccgaccacatcacg
gtccacccgcgcctgctgccgcagctccagcgccgggcgacgatggtcgaggacggcacg
atcgactggggcatgggcgagaccctcgccttcggctccctgctgctggagggcgtcccg
gtccgcctggcgggccaggactcccagcgcggcaccttcggccagcgccacgcggtcatc
atcgaccgcaacaccggcgaggagtacacgccgctgcagtacctctccgaggagcaggcg
cggctgaacgtgtacaactcgctgctgtcggagtacgcggcgatgggcttcgagtacggc
tactcgctggcccgcccggacgcgctggtgctgtgggaggcccagttcggcgacttcgtc
aacggcgcgcagacggtcgtggacgagttcatctcctccgcggagcagaagtggggccag
acctccggcgtcgtcctgctcctcccccacggctacgagggccagggcccggaccactcc
tcggcccgcccggagcgcttcctccagctctgcgcccagaacaacatgacggtcgccatg
ccgacctcgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcaccac
aagccgctggtcgtcttcaccccgaagtcgatgctgcgcctgaaggcggcggcctcgaag
gcggaggagttcaccaccggccagttccgcccggtcatcggcgacgcctccgtcgacgcg
gccgcggtcaagaaggtcgtcttctgctccggcaaggtctactacgacctcgacgccgag
cggaagaagcgcggtgtgacggacacggcgatcatccgcatcgagcgcctgtacccgctg
ccgggtgccgagctccaggccgagatcgccaagtacccgaacgccgagaagtacctgtgg
gcccaggaggagccggcgaaccagggtgcctggccgttcatcgcgctcaacctgatcgac
cacctggaccttgccgtcggcgccgacgtcccgcacggtgagcgcctgcgccgcatctcg
cgtccgcacagctcgtccccggccgtcggttccgcgaagcggcaccaggccgagcaggag
cagctcgtgcgcgaggtgttcgaggcgtaa
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