Streptomyces sp. CFMR 7: ABE83_11015
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Entry
ABE83_11015 CDS
T04074
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
scz
Streptomyces sp. CFMR 7
Pathway
scz00020
Citrate cycle (TCA cycle)
scz00630
Glyoxylate and dicarboxylate metabolism
scz00785
Lipoic acid metabolism
scz01100
Metabolic pathways
scz01110
Biosynthesis of secondary metabolites
scz01120
Microbial metabolism in diverse environments
scz01200
Carbon metabolism
scz01210
2-Oxocarboxylic acid metabolism
Module
scz_M00009
Citrate cycle (TCA cycle, Krebs cycle)
scz_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
scz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
ABE83_11015 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
ABE83_11015 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
ABE83_11015 (kgd)
Enzymes [BR:
scz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
ABE83_11015 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
ABE83_11015 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
ABE83_11015 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
ABE83_11015 (kgd)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
ALC27564
UniProt:
A0A0M4DN62
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Position
2777883..2781704
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AA seq
1273 aa
AA seq
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MSSQSPSNSSISTDQASPGTDPAAAFGANEWLVDEIYQQYLQDPSSVDRAWWDFFADYKP
GSSGTADKPAPGAAASGAAATQAPAATTPAQPAAPAAAAPAPAKPAAAAPAAPAPAKAAP
AAAPAKPAAAKPAAAPAKPKAKADEATEAPAGPEYVTLRGPSAAVAKNMNASLELPTATS
VRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQALKAMPSMNYSFAEKDGKPT
LVKPDHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQAYEDIVRRARIGKLGMDD
FTGVTASLTNPGGIGTVHSVPRLMPGQGLIMGVGAMDYPAEFQGTSQDTLNKLGISKVMT
LTSTYDHRVIQGAASGEFLRIVSQLLLGQNEFYDEIFKALRIPYEPVRWLTDIDASHDND
VTKAARVFELIHSYRVRGHVMADTDPLEYRQRKHPDLDITEHGLTLWDLERDFAVGGFAG
KSMMKLRDILGVLRESYCRTTGIEFMHIQDPKQRKWLQDRVERPRAQQPEREEQLRILRR
LNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAEARLDEVVIGMAHRGRLNV
LANIVGKSYAQIFREFEGNLDPRSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLAANPSHL
EAVDPVLEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVVAETLNMSQLRGYRTGG
TVHVVINNQVGFTAAPESSRSSMYATDVARMIEAPIIHVNGDDPEAVVRVARLAFEFRQA
FNKDVVIDLICYRRRGHNEGDNPEFTNPQMYTLIDKKRSVRKLYTESLIGRGDITLEEAE
QALQDFQGQLEKVFAEVREATSQPAAPHVPEPQAAFPVAVDTAVSAEVIKRIAESQVNIP
ESITVHPRLMPQMQRRAASVENGTIDWGMGETLAIGSLLMEGTPVRLAGQDSRRGTFGQR
HAVLVDQVTGEDYTPLLYLTEDQARYNVYDSLLSEYAAMGFEYGYSLARPESLVIWEAQF
GDFVNGAQTVVDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARPERFLQMCAQDNM
TVAMPTLPSNYFHLLRWQVHNPHHKPLIVFTPKSMLRLKAAASKIEEFTSGGFRPVIGDD
TVKAEDVRKVVFVSGKLFYDLDAEREKRGDTETALIRLERLYPLPGAEIQAEIAKYPNAE
KYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAKRHQ
AEQTQLVNEVFEA
NT seq
3822 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgtctcagtcccccagtaactcgagcatctcgaccgaccaagccagcccgggtacc
gacccggccgccgctttcggcgccaatgagtggctcgtcgacgagatctaccagcagtac
ctccaggatcccagttcggtcgatcgcgcctggtgggacttcttcgccgactacaagccg
ggttcctccggcacggcggacaagcccgctcccggcgccgcagcctcgggggctgcggca
acccaggccccggccgccaccaccccggcgcagcccgcggccccggccgccgccgctccg
gccccggcgaagcccgccgccgctgccccggcagccccggcaccggccaaggccgccccg
gccgcggctccggcgaagcccgcggcggccaagcccgccgccgcgcccgccaagccgaag
gccaaggcggacgaggccaccgaggccccggccggaccggagtacgtgacgctgcgcggc
ccctccgccgccgtcgcgaagaacatgaacgcctcgctggagctgccgacggccacgtcc
gtccgcgcggtcccggtgaagctgctcttcgacaaccgcatcgtcatcaacaaccacctc
aagcgcgcccgcggcgggaagatctccttcacccacctcatcgggtacgcgatggtccag
gccctcaaggccatgccgtcgatgaactactccttcgcggagaaggacggcaagccgacc
ctggtcaagccggaccacgtcaacctgggtctggccatcgacctggtgaagccgaacggc
gaccgccagctcgtcgtcgcggccatcaagaaggccgagacgctcaacttcttcgagttc
tggcaggcgtacgaggacatcgtccggcgcgcccgcatcggcaagctcggcatggacgac
ttcaccggcgtcaccgcctcgctgaccaaccccggcggcatcggcaccgtccactccgtg
ccccgcctgatgcccggacagggcctcatcatgggcgtcggcgcgatggactacccggcg
gagttccagggcacctcccaggacaccctgaacaagctcggcatctcgaaggtcatgacg
ctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggcgagttcctgcgg
atcgtctcgcagctcctgctcggccagaacgagttctacgacgagatcttcaaggccctg
cgcatcccgtacgagccggtccgctggctcacggacatcgacgcgtcgcacgacaacgac
gtgacgaaggccgcgcgcgtcttcgagctgatccactcctaccgggtccgcggccacgtc
atggccgacaccgacccgctggagtaccgccagcgcaagcaccccgacctcgacatcacc
gagcacggcctcaccctgtgggacctggagcgggacttcgcggtcggcgggttcgccggc
aagtcgatgatgaagctccgcgacatcctcggcgtgctgcgcgagtcgtactgccgcacc
accggcatcgagttcatgcacatccaggacccgaagcagcgcaagtggctccaggaccgg
gtggagcggccccgcgcccagcagcccgagcgcgaggagcagctccgcatcctgcgccgg
ctgaacgcggccgaggcgttcgagaccttcctccagaccaagtacgtcggtcagaagcgg
ttctcgctggagggcggcgagtccgtcatcccgctgctcgacgcggtcatcgactccgcc
gccgaggcccgcctcgacgaggtcgtcatcggcatggcccaccgcggccgcctcaacgtg
ctggcgaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgagggcaatctc
gacccgcgctcgatgcacggctccggcgacgtcaagtaccacctgggcgccgagggcacc
ttcaccggtctggacggcgagcagatcaaggtctcgctggccgccaacccctcgcacctg
gaggcggtcgacccggtcctggagggcatcgcccgcgccaagcaggacatcatcaacaag
ggcggcacggacttcacggtcctgcccgtcgcgctccacggcgacgcggccttcgcgggc
cagggcgtcgtcgccgagacgctcaacatgtcgcagctgcgcggctaccgcaccggcggc
accgtgcacgtggtgatcaacaaccaggtcggcttcaccgccgccccggagtcctcgcgc
tcctcgatgtacgccaccgacgtggcgcgcatgatcgaggcgccgatcatccacgtcaac
ggtgacgacccggaggccgtggtccgtgtcgcgcggctcgccttcgagttccggcaggcg
ttcaacaaggacgtcgtgatcgacctcatctgctaccgccgccgcggtcacaacgagggc
gacaacccggagttcaccaacccgcagatgtacacgctgatcgacaagaagcgctcggtg
cgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaagaggccgag
caggcgctccaggacttccagggccagctggagaaggtcttcgccgaggtccgcgaggcc
acctcgcagcccgccgccccgcacgtcccggagccgcaggccgcgttcccggtggccgtg
gacacggcggtctccgccgaggtcatcaagcggatcgccgagtcccaggtcaacatcccc
gagtcgatcaccgtccacccccgtctgatgccgcagatgcagcgtcgcgcggcctcggtg
gagaacggcacgatcgactggggcatgggcgagaccctggccatcggttcgctgctgatg
gagggcaccccggtccggctcgccggccaggacagccgccgcggcaccttcggccagcgc
cacgcggtcctggtggaccaggtcaccggcgaggactacaccccgctgctgtacctcacc
gaggaccaggcccggtacaacgtctacgactcgctgctcagcgagtacgcggcgatgggc
ttcgagtacggctactcgctggcccgcccggagtcgctggtcatctgggaggcccagttc
ggtgacttcgtcaacggcgcgcagaccgtcgtggacgagttcatctcctcggccgagcag
aagtggggccagacctccggcgtcacgctgctgctgccgcacggctacgagggccagggc
ccggaccactcgtccgcccgcccggagcgcttcctccagatgtgcgcgcaggacaacatg
acggtcgcgatgccgaccctcccctcgaactacttccacctgctgcgctggcaggtgcac
aacccgcaccacaagccgctcatcgtcttcaccccgaagtcgatgctgcgtctgaaggcg
gcggcgtcgaagatcgaggagttcaccagcggcggcttccgtccggtgatcggcgacgac
accgtcaaggcggaggacgtccgcaaggtcgtcttcgtctcgggcaagctcttctacgac
ctggacgccgagcgggagaagcgcggcgacacggagaccgcgctcatccggctggagcgg
ctgtacccgctgccgggtgcggagatccaggccgagatcgccaagtacccgaacgccgag
aagtacctgtgggcccaggaggagccggccaaccagggtgcgtggccgttcatcgcgctc
aacctgatcgaccacctggacctggccgtgggcgcggacgtgccgcacggcgagcgcctg
cgccgcatctcgcggccgcacggctcgtccccggcggtcggctcggccaagcgccaccag
gcggagcagacgcagctggtcaacgaggtcttcgaggcctga
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