KEGG   Streptomyces griseofuscus: HEP81_02473
Entry
HEP81_02473       CDS       T07010                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
sgf  Streptomyces griseofuscus
Pathway
sgf00470  D-Amino acid metabolism
sgf00550  Peptidoglycan biosynthesis
sgf01100  Metabolic pathways
sgf01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sgf00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    HEP81_02473
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    HEP81_02473
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    HEP81_02473
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sgf01011]
    HEP81_02473
Enzymes [BR:sgf01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     HEP81_02473
Peptidoglycan biosynthesis and degradation proteins [BR:sgf01011]
 Precursor biosynthesis
  Amino acid ligase
   HEP81_02473
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4 ATPgrasp_ST
Other DBs
NCBI-ProteinID: QNT92795
UniProt: A0A7H1PXL5
LinkDB
Position
complement(2819942..2821192)
AA seq 416 aa
MDTVRNPPVFVRSGAEPTLYPGSTNGYSQRDMSTENLPQSPEQPSRKPRVAVVFGGRSSE
HGISVVTAGAVLKAIDRTKYDVLPIGITRDGRWALTADEPERMAITDRALPAVEDLAESH
EGDVVLPVAPANREVVYSEPGSVPKALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVG
AGVLASAVGQDKEYMKRVFTSFGLKVGPYVVIRPREWQQDQAAARKKIVDFAGEHGWPLF
VKPARAGSSIGITKVDDLSGLDEAIAEAQSHDPKILIEAAITGREIECGVLEFEDGPRAS
LPAEIPPPDAHAYYDFEAKYIDSTPGIVPAPLTEEETTEIRRLAVDAFEAASCEGLVRAD
FFLTEDGEFVINEINTLPGFTPISMYPQMWQATGVGYPELIDLLVQAALRRSTGLR
NT seq 1251 nt   +upstreamnt  +downstreamnt
atggacactgtgcgaaatccgcccgtttttgtgcgttccggggcggagccgacgctgtat
ccgggctctaccaacgggtactctcaacgcgatatgagcaccgagaaccttccccagagc
cctgagcagccgtcgcgcaagccccgcgtggccgtcgtgttcggtggccgcagctccgaa
cacgggatctccgtggtcaccgcgggcgccgtcctcaaggccatcgaccggacgaagtac
gacgtcctgccgatcggcatcacccgggacggccgctgggcgctgacggccgacgagccg
gagcggatggccatcaccgaccgcgccctgcccgccgtcgaggacctggcggagtcgcac
gagggcgatgtggtgctccccgtcgcccccgccaaccgcgaggtcgtctacagcgagccc
ggctccgtgcccaaggcgctcggcgaggtcgacgtcgtcttcccggtgctgcacggcccc
tacggcgaggacggcaccctccagggcctgctggagctgtccggagtgccgtacgtgggc
gcgggcgtgctcgcctcggccgtcggccaggacaaggagtacatgaagcgggtcttcacc
tccttcgggctcaaggtcggcccttacgtggtgatccgcccccgcgagtggcagcaggac
caggccgccgcccgcaagaagatcgtggacttcgccggtgagcacggctggccgctgttc
gtgaagcccgcgcgggccggctcctccatcggcatcaccaaggtcgacgacctctccggc
ctggacgaggcgatcgccgaggcgcagtcgcacgacccgaagatcctgatcgaggcggcg
atcaccggccgcgagatcgagtgcggtgtcctggagttcgaggacggccccagggcctcg
ctcccggccgagatcccgccgccggacgcgcacgcgtactacgacttcgaggccaagtac
atcgactccacgcccggcatcgtcccggcgccgctcaccgaggaggagaccaccgagatc
cggcggctcgcggtggacgcgttcgaggccgcgtcctgcgaggggctggtgcgcgcggac
ttcttcctcaccgaggacggggagttcgtgatcaacgagatcaacacgctgcccgggttc
accccgatctcgatgtacccgcagatgtggcaggcgaccggggtcggctaccccgagctg
atcgacctgctggtgcaggccgcgctgcgccggtccaccggactgcgctga

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