Streptomyces griseofuscus: HEP81_07911 Help Entry HEP81_07911       CDS       T07010                                  Name (GenBank) type I polyketide synthase   KO K24563   6-deoxyerythronolide B synthase EryAII [EC:2.3.1.94] Organism sgf  Streptomyces griseofuscus Pathway sgf00522   Biosynthesis of 12-, 14- and 16-membered macrolides sgf01052   Type I polyketide structures sgf01100   Metabolic pathways Brite KEGG Orthology (KO) [BR:sgf00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     HEP81_07911    00522 Biosynthesis of 12-, 14- and 16-membered macrolides     HEP81_07911  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:sgf01008]     HEP81_07911 Enzymes [BR:sgf01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.94  6-deoxyerythronolide-B synthase      HEP81_07911 Polyketide biosynthesis proteins [BR:sgf01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Erythronolide PKS      HEP81_07911 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt KR Ketoacyl-synt_C KAsynt_C_assoc PS-DH PP-binding PKS_DH_N adh_short ADH_zinc_N_2 ADH_zinc_N Thiolase_N Epimerase ADH_N adh_short_C2 Docking Motif Other DBs NCBI-ProteinID:  QNT98139 UniProt:  A0A7H1QCV9 LinkDB All DBs Position pSGRIFU1:complement(63207..74177) Genome browser AA seq 3656 aa AA seqDB search MTDNDKVASYLRRATLDLRAARRRIHELEADPVAIVGTACRLPGGIETPEAFWEVLAAGE ERLSAFPEDRGWDLTGLYHPDPDHPGTTYVRTGAFLERAGEFDAAFFGVSPREAAAMDPQ QRLLLETSWELIENAGLDPHSLRGTDTGVFLGVARHGYGDTGGSAEDAEGYTVTGAAPSV ASGRIAYTLGLEGPAITLDTACSSSLVALHLAVASLRRGECGLAIVGGAAVMAGPEVFVD FARQRALAADGRSKAFGAGADGFGFGEGVAVLLLERLSDARRRGHTVLAVVRGTGINQDG ASNGLAAPSRAAQRKVIEQALANAGVAPGDVDAVEAHGTGTTLGDPIEAHALLDTYGRGR GPQRPLWLGSAKSNIGHTQGAAGAVGVLKMVLALRHERLPRTLHAEEASPHVDWSSGAVA LLAEEQHWPRGERPRYAAVSAFGISGTNAHVVLQEAPAPEETGERAAPRPATPQHPVPLV VSARSEEALRAQARRLSDVLADTDAELPGIGLTLATARARHEHRAVVVAGSRDLALHGMR EVAAGAARLTGTVESGGRSAVFLFPGQGSQWAGMGADLLAWSPVFAETIRACDEAMAPWQ DWSVAAVLRQQPGAPGLDRVDVVQPALFAVMVSLAALWRSYGVEPAAVAGHSQGEIAAAY VAGALTLEDAARLVVLRSRLLRSLAGKGAMAAVALDEAAVRELLVPYAGAVEVAAVNGPA SVVVSGEPAAVDSLVADCAGRGARARTIDVDYASHSAQMEEVREELAAALRDLRPGRARV PFYSTVTGRPMDGGELDAGYWYRNLREPVRLHDVVRLLADAHHDTFIEVSPHPVLAATVE ETLEAAGREPGAALALGTLRRGAPGPESFLTFAASAHVEGVDVRWQPAFGDDARPVALPT YPFQRKHYWTAPAGPARATGGVTYRVSWTPLPAPEPADARGPWLIVGPAASPAWAGLLPA AVREAGGTPLECALDPGLDRAGAAAALTAALAGTTGVRGVLSLLAADESDHPGRPGVPAG AVATLTLAQALADAGVDAPLWCLTRGAVQTDEDDGIGSYAQNAVHGLGRVAGLELGRRWG GVLDLPHPDGADAALLGRVPGLLAGAHAAEDHLALRPGGLYGRRLVPVRTPATTDGTGPR LHGTVLLTGADSPIGARLARWAADSGADHLLLVGEADEELLNALRERGTTATRCAADEDA LRAAVEAAPHDISTVVHAATRTEFGPVLATDPEDFAATLQAKTGLALTLAAVLDGRPVER EIHCSSVAGVWGGAGMAGYAAGSACLDAFAAHRRAQGHPSTAVAFSPWALPGTVPSAPQA AQRGLRGLSADRALAALTSALDSGESAVAVSDVDWPAFAAGFGAVRPTALFAEISEARET AEPPAAPAAPDGSPAADLAARLTARTPAQREELLIGVVAEATAAVLGHDSAEDVSARRAF TELGLDSLGSVQLRKRLSAATGLRLPASLVFDHPTVTRLARHLLSLLAADSGPELAAAVG SAPPSAEDEPIAIVGMSCRFPGGIGSPEELWRAVVDGQDLTGELPRDRGWELGALYHPDP DHPGTSYSDRGGFLADAAGFDAEFFGITPREALAMDPQQRLMLEVAWEAVERGGIDPDAL RGSRVGVFVGSNGQSYMPLLRGEADRVEGYQGLGNSASVLSGRLAYTFGWTGPALTVDTA CSSSLVGIHLAIRALRDGECAMALAGGVTVICDPYTFVDFSRQRGLAADGRCKPFSAQAD GFGLAEGAGALLLEPLSRAIESGHPVLAVLRGSAVNQDGASNGLAAPNGPAQEEVIRQAL ADARLSAADIDLVEAHGTGTRLGDPIEAGALQATYGAPRARPLALGSVKSNIGHTQAAAG VAGVIKAVLAMRHGVIPRSLHAEELSPEIDWSPGTIRVQRENEDWPAGPRVRRAGVSSFG VSGTNAHVVLEEAPAVPESAPAGAEAAPVLPEAVAANVAAPAGRPGGRGLAADTAALVLS ARTPSAVRAQAGALAALLRTSPATPLADTARTLATGRTRLDIRAAVLGDDRDSVCAALDA LAAGEAAADVVPPRTAAPRKAVLVFPGQGSQWAGMAADLLSQSEIFAAAMADCAAALAPY TDWDLLATLRGDGPEDAFERPDVVQPLLFAVMVSLAALWRAHGVEPAAVVGHSQGEIAAA CVAGALTLDTAAKVVALRSKVLGELNGQGGMASVTAAPGELREALAPWDGRLSVAAVNGP RSLVVAGEAAALDEFLGSPRAEEMSPRRIAVGYGSHSPQVAQVEQRLADVLGTVPARSAA VPFCSTVTGAPLDTAGLDAAYWYRNLRGTVRLDQAVRTLMEQGFDTFVEVSPHPVLLPGI EQTAEDLGRDVVTLASLRRDRPGARTFLRNLLEAHADGLPVDLLPALEPGGTAELPTYPF EHTSYWPRPCRTRADAAPSGMDSVAHPVLSAALETPDGGHVLTGRITLGDQPWLADHAVG GETLLPGSALVDLALTAGRHAGTPAVAELVLCAPLLPGAATAVRVTVGAPAADGTRTVDI HARDTDAPGTPWTRHATGVLGEAAPPPATPAVWPPADARPINLDAAYARLADRGYGYGPA FRALRAAWQRGAEVFAEAELPAAAGPDDAESAGYLLHPVLLDAAAQTLGLGPLADRDGAF LPFSWTGTTLYASGATTIRVSAAPAGADAMSLSVTDPAGAPVAVVSAVTVRPAGGEPGPR AGEETGADDLYHLTWRPLPETTGRAVGCATIGGPCGLGKDHPDLAALAAAVAAGEPEPEA VVVPCRPWQAADPAGSVRESVLHAAGLVRQWLDAPERTGRLVFLTRNAVSTGPADTAADP AQAAVWGLVRSAQAESPGNFALVDIADGADPAVLAALPAVLDHPQLAVRGDLALVPRLAS TRTAPALLPPRTPARLEPAGTSLDALAFAAAPDAGRQPGPGEVRVELRACGVNFRDVLIA LGMYPGAAVMGTEGAGVVTAVGPDVTGVAVGDRVMGLFEGAFGPVAVTDHRLVTPVPPGW STTEAAALPIAFTTAHYALHDLAGVRPGQAVLVHAAATGVGMAAVRLARLAGAEVFATAS PAKQGVLRSLGLDDDHIASSREPGFGRRFRAVRGGRGMDVVVNSLTGALLDESAELLAEG GAFVEMGKTDLRDADRFRGRYLPFDLAEAGADRLGAILAEVASLAAGGELGRQTVTAWPL QRASAALQHMSTGRHTGKLVLVQPAPLDPEGTVLVTGGTGTLARLLARHLVTEHGVRHLL LLGRRGPDAPGAARFEAELGELGATVTTRACDVSDRAALAAALDGIPAGHPLTGVVHTAG VLADGLAASLGEDELGTVLAPKADAAWHLHELTADREPNFFVLFGSGASVLAGPGQGAYA AANAALDALARYRQARGLPATSLGWGLWEEASGLTGALDERDTRRMARAGMRPLPTARAL ALFDLAIRRGDAVAYPLHLDTARAQGAQDAPEVLRGLLHTPLRRAARDQSGGDGLAARLA PLPRPDRLAALTHAVQAQAAAVAGYDTADAVAARRQFKDLGFDSLASVELRNRLGSALGL RLPSTLVFDHPTPEAVAVFVDGRLFAGADAAGAPAPEPGRSVAEHLAALEAVLEGWQEAG EDTAGERRAIGARLTALSDRWSAVAAGDSRTAVDTVDDEELFALLDQRFGEGNEER NT seq 10971 nt NT seq  +upstreamnt  +downstreamnt gtgacggacaacgacaaggtcgcttcatacctgcgccgggccaccctggacctgcgagcg gcccggcggcgcatccacgagctggaggccgacccggtcgcgatcgtcggcacggcctgc cggctgcccggcgggatcgagacccccgaggccttctgggaggtgctggcggcgggcgag gaacggctgtccgccttccccgaggaccgcggctgggacctgaccggcctctaccacccg gaccccgaccaccccggcaccacctacgtgcgcaccggcgcgttcctggagcgcgcgggc gaatttgacgccgccttcttcggcgtctccccgcgcgaggccgccgcgatggacccccag cagcgccttctgctggagacgagctgggagctgatcgagaacgccggactggacccgcac agcctgcgcggcaccgacaccggggtgttcctcggcgtcgcccggcacggctacggcgac accggcggctccgccgaggacgccgagggctacacggtcaccggcgcggcgccctccgtc gcctccggccggatcgcctacaccctcggtctcgaaggccccgccatcaccctggacacg gcctgctcctcctccctcgtggccctgcacctggcggtggcgtcgctgcgccgcggcgag tgcggcctcgcgatcgtgggcggcgccgcggtgatggccggccccgaggtgttcgtcgac ttcgcccggcagcgcgccctcgccgccgacggccgatccaaggcgttcggcgcgggcgcc gatggcttcggcttcggcgagggcgtcgcggtgctcctcctggagcgcctgtcggacgcc cggcgccgcgggcacaccgtgctcgccgtcgtccgcggcaccggcatcaaccaggacggc gccagcaacggcctggccgcacccagcagagccgcccagcgcaaggtcatcgaacaggcc ctggccaacgcgggcgtggcccccggcgatgtcgacgcggtcgaggcgcacggcaccggc accaccctcggcgaccccatcgaggcccacgccctgctcgacacctacggccggggccgc ggcccgcagcggccgctgtggctcggctcggcgaagtcgaacatcggccacacccagggc gccgccggcgcggtcggcgtgctcaagatggtgctcgccctccggcacgagcggctgccc aggaccctccacgccgaggaggcctcgccgcacgtcgactggtcctcgggcgcggtcgcg ctgctcgccgaggagcagcactggccgcgcggcgaacggccccggtacgccgccgtgtcg gcgttcggcatcagcggcaccaacgcccacgtcgtcctccaggaagcccccgcacccgag gagaccggcgaacgcgcggccccgcggccggccacgccgcagcacccggtgccgctggtc gtctcggcccgcagcgaggaggccctgcgcgcccaggcacggcggctgtccgacgtgctc gcggacaccgacgccgaactgcccggcatcggcctgacgctggccaccgcacgggcccgg cacgagcaccgcgcggtggtcgtggccggctcccgcgacctcgcgctgcacgggatgcgc gaggtggccgccggtgcggcacgcctcacgggcaccgtcgaatcgggcgggcgctccgcc gtgttcctcttccccggccagggctcccagtgggcgggcatgggcgccgacctgctggcc tggtccccggtgttcgccgagacgatccgggcctgcgacgaggcgatggccccctggcag gactggtcggtggccgcggtgctgcggcagcagcccggcgcccccggactcgaccgcgtc gacgtggtgcagcccgcgctgttcgccgtgatggtgtccctggccgcgctgtggcgctcc tacggcgtggaaccggcggccgtggcgggacactcgcagggcgagatcgccgcggcgtac gtcgccggggcgctgacactggaggacgccgcccggctcgtggtgctgcgcagccgcctg ctgcgatcactggccggaaagggcgccatggcggccgtggcgctggacgaggccgcggtc cgcgagctgctcgtgccgtacgcgggcgccgtcgaggtggccgcggtcaacgggcccgcc tccgtcgtcgtctccggcgaacccgccgcggtggactccttggtggcggactgcgccggc cgcggagcgcgcgcccggaccatcgacgtggactacgcctcgcactccgcgcagatggaa gaggtccgcgaggaactggccgcggccctgcgggacctgcgccccggccgcgcgcgggtc ccgttctactcgacggtgaccggccgcccgatggacggcggggaactggacgccggctac tggtaccgcaacctgcgcgagccggtgcgcctgcacgacgtcgtacgcctcctcgcggac gcgcaccacgacaccttcatcgaggtcagcccgcacccggtgctggcggcgacggtcgag gagacgctggaggcggcgggccgggagcccggcgcggccctggccctgggcaccctgcgg cgcggcgcgcccggcccggagtccttcctcaccttcgcggcgagcgcccacgtcgagggc gtggacgtgcgctggcagcccgccttcggcgacgacgcgcggcccgtcgcgctgcccacg tacccgttccagcgcaagcactactggacggcccccgccgggcccgcccgcgccaccggc ggggtgacctaccgcgtgtcgtggacgccgctgcccgccccggagccggccgacgcgcgc gggccctggctgatcgtcggcccggccgcgtccccggcctgggccggcctgctgccggcc gcggtccgcgaggccggcggcacgccgctggagtgcgccctggaccccggcctggaccgc gccggggccgccgccgcgctcaccgcggccctcgcgggcaccaccggtgtgcggggcgtg ctctcgctgctcgcggccgacgaatcggaccaccccggccggccgggcgtgcccgccggc gcggtcgccaccctcacgctcgcgcaggccctcgccgacgccggggtggacgcgccgctg tggtgcctcacccgcggcgccgtgcagacggacgaggacgacggcatcgggtcgtacgcg cagaacgccgtgcacggcctgggccgggtcgccggtctggaactcgggcggcgctggggc ggcgtgctggacctgccgcacccggacggggccgacgcggccctgctcggccgggtgccg ggcctcctggccggcgcgcacgccgccgaggaccacctcgccctgcggcccggcggcctg tacgggcggcggctggtgccggtgcggaccccagccacgacggacggcaccggcccgcgc ctgcacgggaccgtactgctgaccggggcggacagcccgatcggcgcccggctcgcccgg tgggcggccgacagcggcgccgaccatctcctgctcgtcggcgaggcggacgaggaactg ctgaacgcgctgcgggagcgcggcacgacggccacccgctgcgcggcggacgaggacgcc ctgcgggccgccgtcgaagccgccccgcacgacatcagcaccgtcgtacacgccgcgacc cgcacggagttcgggccggtcctcgccaccgacccggaggacttcgccgccaccctccag gccaagaccggactcgccctgaccctcgccgcggtcctcgacggccggccggtggagcgg gagatccactgctcgtcggtggccggcgtctggggcggtgccggcatggccggatacgcg gccggcagtgcctgcctcgacgcgttcgccgcccaccggcgggcccagggccacccgagc accgccgtggccttcagcccctgggccctgcccggcaccgtgccgtccgccccgcaggcg gcgcagcgcgggctgcgcggcctgagcgccgaccgcgccctcgcggccctcacgtccgca ctggactcgggcgagagcgccgtcgcggtgtccgacgtggactggcccgccttcgccgcg ggcttcggcgcggtgcggcccaccgcgctgttcgcggagatctccgaagcgcgcgagacg gcggagcccccggcggcgcccgccgcaccggacggctcaccggccgccgacctggccgcc cggctcaccgcccgcacgcccgcgcagcgcgaggagctgctgatcggcgtggtcgccgag gccaccgcggcggtcctcggacacgacagcgccgaggacgtcagcgcacggcgggcgttc accgaactgggcctggactcgctgggctcggtgcagctgcgcaagcggctctccgcggcc accggtctgcgcctgcccgcctccctggtgttcgaccacccgaccgtcacccggctcgcc cgccatctgctgtccctgctggccgccgactccggcccggagctcgccgccgcggtgggg agcgcgccgccgagcgccgaggacgagccgatcgccatcgtcggcatgagctgccgcttt ccgggcggcatcggctcgcccgaggagctgtggcgggccgtcgtcgacggacaggacctc accggcgagctgccccgcgaccggggctgggaactgggggccctgtaccaccccgacccc gaccaccccggcaccagctactccgaccggggcgggttcctcgccgacgcggcgggcttc gacgcggagttcttcggcatcaccccccgcgaggcgctcgcgatggatccgcagcagcgg ctgatgctcgaagtcgcctgggaggccgtcgagcggggcggtatcgacccggacgcgctg cgcggcagccgcgtcggcgtgttcgtcgggtccaacggccagtcgtacatgccgctcctg cgcggcgaggccgaccgggtcgagggctaccaggggctcggcaactcggcgagcgtgctc tcggggcgcctcgcctacaccttcggctggacggggccggccctcaccgtggacacggcg tgctcgtcctccctggtgggcatccacctggcgatacgggccctgcgcgacggcgagtgc gccatggcgctggccggcggggtcaccgtgatctgcgacccctacacgttcgtggacttc agcagacagcgcggtctggccgccgacgggcggtgcaagccgttctcggcgcaggccgac ggcttcggtctcgccgagggggccggcgccctgctcctcgaaccgctctcccgagccatc gagtcgggccacccggtgctcgccgtgctgcggggcagtgcggtcaaccaggacggcgcg agcaacggactggccgcgccgaacggtcccgcccaggaggaggtgatccggcaggcgctc gccgacgcccggctgtcggcggccgacatcgacctggtggaggcgcacggcaccggcacc cggctcggcgatccgatcgaggccggcgcgctccaggccacctacggcgcaccgcgcgca cgtcctctggcgctgggctcggtgaagtcaaacatcggccacacccaggccgcggccggt gtcgccggtgtgatcaaggcggtgctggcgatgcggcacggcgtcatcccgcgcagcctg cacgccgaggaactctcccccgagatcgactggtcgccggggacgatccgggtccagcgg gagaacgaggactggccggcgggcccgcgggtgcgccgggccggcgtgtcctcgttcggg gtcagcggcaccaacgcccacgtcgtcctggaagaggcccccgcggtcccggaatcggca ccggccggcgcggaagcggccccagtgctgccggaagcggtggccgcgaacgtggccgca ccggccgggcggcctggcggacgcggtctcgcggcggacaccgcggcactcgtgctctcg gcccgtacaccgagcgcggtgcgcgcgcaggccggcgccctcgcggcgctgctgcgcacc tcgccggcgacccccctggccgacaccgcgcggacgctcgcgaccggccggacccggttg gacatccgggccgcggtactgggcgacgaccgggactcggtgtgcgcggcgctcgacgcg ctggccgccggcgaggcggccgccgacgtcgtgccgccgcgcacggcggccccccgcaag gccgtcctggtcttccccggccagggctcgcagtgggccggcatggccgccgacctcctc agccagtcggaaatcttcgccgccgccatggccgactgcgcggcggcgctcgccccgtac accgactgggacctgctcgccacgctgcgcggcgacggccccgaggacgccttcgaacgg cccgacgtcgtccagccgctgctgttcgcggtcatggtgtcgctggcggcgctgtggcgc gcccacggcgtcgagccggccgccgtggtgggccactcgcagggcgagatcgccgccgcc tgcgtcgccggggccctcaccctcgacaccgccgcgaaggtcgtcgcgctgcgcagcaag gtgctcggcgagctgaacgggcagggcggcatggcctccgtcaccgccgcgcccggcgaa ctccgcgaagccctggccccgtgggacggccggctgagcgtcgccgccgtgaacgggccg cgctccctcgtcgtcgccggcgaggccgccgccctcgacgagttcctcggctccccgcgg gccgaggagatgtccccgcggcggatcgcggtgggctacggctcccactccccgcaggtg gcacaggtcgagcagcggctcgccgatgtcctgggcacggtcccggcccggtccgccgcc gtgcccttctgctcgaccgtcaccggcgccccgctcgacaccgccggactcgacgccgcg tactggtaccgcaacctgcgcggcacggtccgcctcgaccaggccgtacgcaccctcatg gagcagggcttcgacaccttcgtcgaggtcagcccgcacccggtgctgctccccggcatc gagcagaccgccgaggacctcggccgggacgtcgtcaccctcgcctccctgcgccgggac cgccccggcgcgcgcaccttcctgcgcaacctgctggaggcacacgccgacggcctgccc gtcgacctgctgcccgccctggaacccggcgggacggcggaactgccgacctatccgttc gagcacacctcctactggccacgcccctgccgcacccgcgccgacgcggcaccctcgggc atggacagcgtcgcccaccccgtcctgtccgcagcgctggagacacccgacggcggacac gtcctgaccgggcggatcaccctcggggaccagccgtggctggccgaccacgccgtcggc ggcgagaccctgctgcccggcagcgcactggtcgacctcgccctgacggccggccgccac gcgggcacgccggccgtggcggaactggtgctctgcgcccccctgttgcccggtgcggcc accgccgtccgcgtgacggtcggcgcccccgcggcggacggcacccgcacggtggacatc cacgcccgcgacacggacgcgccgggcacgccctggacccggcacgccaccggcgtcctc ggcgaggccgcgccgccgccggccacccccgcggtctggccgccggcggatgcccggccg atcaacctggacgcggcctacgcacgcctggccgaccgcggttacggctacgggcccgcc ttccgggcactgcgcgcggcctggcagcgcggcgcggaggtgttcgccgaggccgaactc ccggcggcggcgggccccgacgacgccgagagcgcgggctacctgctgcaccccgtgctc ctcgacgccgccgcccagaccctcggcctcggccccctcgccgaccgggacggcgcgttc ctgcccttctcctggaccgggaccacgctgtacgcgtccggggccacgacgatccgggtg agcgcggcccccgccggcgccgacgcgatgagcctgtcggtgaccgatcccgcgggagcg ccggtcgccgtcgtgagcgccgtgaccgtgcgtccggccggcggggagcctggcccgcgc gccggggaggagaccggcgccgacgacctctaccacctgacctggcggcccctgcccgag accaccggccgggccgtcggctgcgcgacgatcggcggcccctgcggactcggcaaggac cacccggacctggcggcactggccgcggcggtcgcggccggcgagccggaacccgaggcc gtcgtcgtgccgtgccgtccatggcaggcggcggacccggccggctccgtgcgcgagagt gtgctgcacgccgccgggctcgtgcgccagtggctcgatgcgcccgaacgcaccggccgc ctggtgttcctcacccgcaacgccgtgagcaccggccccgccgacaccgcggcggacccc gcacaggccgcggtctggggcctggtccgctccgcccaggcggagtcaccggggaacttc gcgctcgtcgacatcgccgacggcgccgatcccgcggtcctcgccgccctcccggccgtg ctcgaccacccgcagctggccgtgcgcggcgacctcgcgcttgtgccccggctggcctcg acgcgcaccgccccggccctgctgccgccccgcacgcccgcccgcctggagcccgccggt acctccctggacgccctcgcgttcgcggcggcaccggacgccggccggcagccgggaccg ggtgaggtgcgggtcgaactgcgggcctgcggagtgaacttccgcgatgtcctgatcgcc ctcggcatgtaccccggtgccgccgtcatgggcaccgagggcgccggggtcgtcaccgcc gtcggcccggacgtgacgggcgtcgcggtgggcgaccgggtcatgggcctgttcgaaggc gccttcgggccggtcgcggtcaccgaccaccggctggtcaccccggtcccgccgggatgg agcaccaccgaggccgccgccctgcccatcgccttcaccaccgcccactacgcgctgcac gacctcgccggagtgcggcccggacaggccgtcctggtgcacgccgccgccaccggcgtc ggcatggccgcggtccgcctggcccggctggccggggcggaggtcttcgccaccgccagc cccgccaagcagggcgtgctgcgctcgctcggactcgacgacgaccacatcgcctcgtcc agggagccgggattcggccggcgcttcagggccgtgcgcggcggacgcggcatggacgtc gtggtcaactcgctgaccggcgcactgctcgacgagtcggccgaactcctcgccgaaggc ggtgcgttcgtcgagatgggcaagaccgacctgcgcgacgccgaccggttccgcgggcgc tacctgcccttcgacctcgccgaggcgggagcggaccggctcggcgcgatcctcgccgag gtcgcctccctggcggccggcggcgaactcggccgccagacggtcacggcctggccgctg caacgggcgtcggccgccctccagcacatgagcacgggacggcacaccggaaagctggtg ctcgtccagccggccccgctcgaccccgagggcaccgtgctcgtcaccggcggcaccggc accctggccaggctgctggcccgccatctcgtgaccgagcacggcgtacgccatctgctg ctgctcggccgccgcgggcccgacgcgccgggagcggcccggttcgaagccgaactgggc gaactgggcgcgaccgtgaccacgcgcgcctgcgacgtctccgaccgcgccgcgctcgcc gccgcgctcgacggcatcccggccgggcacccgctgaccggcgtcgtgcacaccgcgggc gtgctcgccgacggcctggccgcgtccctcggcgaggacgaactgggcacggtcctcgcg cccaaggcggacgccgcatggcatctgcacgaactcaccgcggaccgcgaaccgaacttc ttcgtcctgttcggttcgggcgcctccgtgctggccggaccgggccagggcgcgtacgcg gcggccaacgccgcactggacgcgctggcccggtaccggcaggcccgcgggctgcccgcg acgtccctcggctgggggctgtgggaggaggccagcggcctgacgggcgctctggacgag cgggacacccggcggatggcccgcgcgggcatgcggcccctgccgaccgcgcgggcgctg gccctgttcgacctcgcgatccggcgcggcgatgcggtggcgtacccgctgcacctggac accgcgcgggcgcagggcgcccaggacgcgcccgaggtgctgcgcgggctgctgcacacg ccgctgcgccgggccgcgcgggaccagtccggcggtgacggactcgccgcccgcctggcg ccgctgccgcgccccgaccggctcgccgcgctgacccatgccgtacaggcgcaggccgcc gccgtcgccgggtacgacacggccgacgcggtggcagcccgacggcagttcaaggacctc ggcttcgactccctggcctccgtcgaactgcgcaaccggctggggtccgcgctcggcctg cggctgccgagcactttggtcttcgaccacccgacacccgaggcggtggccgtcttcgtg gacggtcggctgttcgccggcgcggacgcggccggcgccccggcgccggagccggggcgc tccgtcgccgagcacctggcggcgctggaggcggtgctggagggctggcaggaggccggc gaggacacggccggtgaacgccgggccatcggggcgcggttgacggccctgtccgaccga tggagcgccgtggccgccggggactcccgcacggccgtcgacaccgtcgacgacgaggaa ctgttcgcactgctcgaccagcggttcggtgaggggaacgaggaacgatga

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