Streptomyces graminofaciens: SGFS_039770
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Entry
SGFS_039770 CDS
T09325
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sgrf
Streptomyces graminofaciens
Pathway
sgrf00470
D-Amino acid metabolism
sgrf00550
Peptidoglycan biosynthesis
sgrf01100
Metabolic pathways
sgrf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sgrf00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SGFS_039770
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SGFS_039770
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SGFS_039770
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sgrf01011
]
SGFS_039770
Enzymes [BR:
sgrf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SGFS_039770
Peptidoglycan biosynthesis and degradation proteins [BR:
sgrf01011
]
Precursor biosynthesis
Amino acid ligase
SGFS_039770
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
BBC32683
LinkDB
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Position
complement(4576743..4577945)
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AA seq
400 aa
AA seq
DB search
MGADWRTTNGYSQRDMSSENLPQSPEQPSRKPRVAVVFGGRSSEHGISVVTAGAVLRAID
RTKYDVLPIGITRDGRWALTADEPERMAITERRTPEVEELAESREGGVVLPVDPANREVV
YSEPGSVPKALGEVDVVFPVLHGPYGEDGTLQGMLELSGVPYVGSGVLASAVGQDKEYMK
RVFTSFGLKVGPYAVIRPREWQLDESAARKKIIDFAGEHGWPLFVKPARAGSSIGITKVE
DLTDLDEAIAEAQRHDPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPPSAHAYYDF
EAKYIDSTPGIVPAPLTPEETAEVQRLAVDAFEAASCEGLVRADFFLTEGGDFVINEINT
MPGFTPISMYPAMWKASGIEYAELVDLLVQAALRRSTGLR
NT seq
1203 nt
NT seq
+upstream
nt +downstream
nt
atgggcgctgactggcgcactaccaacgggtactctcaacgcgatatgagcagcgagaac
ctcccccagagccctgagcagccgtcccgcaagccgcgcgtggccgtcgtcttcggcggc
cgcagctcggaacacgggatctccgtggtcacggccggcgccgtactgcgcgccatcgac
cggacgaagtacgacgtcctgccgatcggcatcacgcgcgacggccgttgggcgctcacc
gccgacgaaccggaacgcatggcgatcaccgagcgccgtacgcccgaggtcgaggaactc
gccgagtcgcgggagggcggcgtcgtcctcccggtcgaccccgccaaccgcgaagtcgtc
tacagcgagcccggttcggtacccaaggcgctcggcgaggtcgacgtcgtcttccccgtc
ctgcacggcccgtacggcgaggacggcaccctccagggcatgctggagctctccggcgtc
ccctacgtgggctccggcgtactcgcctcggccgtcggccaggacaaggagtacatgaag
cgggtgttcacctccttcgggctcaaggtcggcccgtatgcggtgatccggccgcgcgag
tggcagctggacgagtcggccgcccgcaagaagatcatcgacttcgccggtgagcacggc
tggccgctgttcgtgaagcccgcgcgcgcggggtcgtcgatcggcatcaccaaggtcgag
gacctcaccgacctcgacgaggcgatcgccgaggcccagcggcacgacccgaagatcctc
gtcgaggcggcgctgcgcggccgcgagatcgagtgcggcgtcctggagttcgaggacggc
ccgcgcgcgtccgtccccgccgagatcccgccgccgagcgctcacgcgtactacgacttc
gaggccaagtacatcgactcgacgccggggatcgtgcccgcgccgctgacgccggaggag
accgctgaggtccagcggctcgcggtggacgcgttcgaggcggcgtcgtgcgaggggctg
gtgcgggcggacttcttcctcacggaggggggcgacttcgtcatcaacgagatcaacacg
atgccggggttcacgccgatctcgatgtacccggcgatgtggaaggcgagcgggatcgag
tacgccgagttggtggacctcttggtgcaggccgctctgcggcgttcgacggggctgcgg
tag
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