Streptomyces hygroscopicus subsp. jinggangensis TL01: SHJGH_6150
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Entry
SHJGH_6150 CDS
T02531
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
sho
Streptomyces hygroscopicus subsp. jinggangensis TL01
Pathway
sho00020
Citrate cycle (TCA cycle)
sho00630
Glyoxylate and dicarboxylate metabolism
sho00785
Lipoic acid metabolism
sho01100
Metabolic pathways
sho01110
Biosynthesis of secondary metabolites
sho01120
Microbial metabolism in diverse environments
sho01200
Carbon metabolism
sho01210
2-Oxocarboxylic acid metabolism
Module
sho_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sho_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
sho00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SHJGH_6150
00630 Glyoxylate and dicarboxylate metabolism
SHJGH_6150
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SHJGH_6150
Enzymes [BR:
sho01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SHJGH_6150
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SHJGH_6150
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SHJGH_6150
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SHJGH_6150
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AGF65813
LinkDB
All DBs
Position
complement(6960554..6964066)
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AA seq
1170 aa
AA seq
DB search
MKPAAAPAQAPAPAPAPAAKAPAPAKPAQPAQAPAQPAAKPAPAEAPEGPELITLRGPAA
AVAKNMNASLELPTATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGFAMVQAIK
AMPSMNWSFGEKDGKPTLVKPPHVNLGLAIDLVKPNGDRQLVVAAIKKAETLNFFEFWQA
YEDIVRRARDGKLTMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQ
GTSQDTLNKLGISKVMTLTSTYDHRVIQGAASGEFLRQVANLLLGENGFYDGIFEALRIP
YEPVRWLKDIDASHDDDVTKAARVFELIHSYRVRGHVMADTDPLEYKQRKHPDLDITEHG
LTLWDLERDFAVGGFAGKSMMKLRDILGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVER
PHAKMEREEQLRILRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESR
LDEVVIGMAHRGRLNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGL
DGEQIKVSLAANPSHLETVDPVIEGIARAKQDIINKGGTDFTVLPVALHGDAAFAGQGVV
AETLNMSQLRGYRTGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDP
EAVVRVARLAFEFRQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLY
TESLIGRGDITLEEAEQALQDYQGQLEKVFTEVREAVTTQQATGPVSDPQAEFPVAVNTA
ISTEVVKRIAESQVNIPDSFHVHPRLLPQLQRRAAMVEDGTIDWGMGETLAVGSLLLEGT
PVRLSGQDSQRGTFGQRHAVLIDRETGEEYTPLQYLAEDQARYNVYNSLLSEYAVMGFEY
GYSLARPDALVMWEAQFGDFVNGAQTVVDEYISAAEQKWGQTSGVTLLLPHGYEGQGPDH
SSARVERFLQLCAQNNMTVAMPTLPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAAS
KTEEFTSGQFRPVIGDTAADPAAVRKVVFVAGKLYYDLEAERQKRGVTDTAIIRIERLYP
LPGAEIQAEVNKYPNAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRI
SRPHSSSPAVGSAKRHQAEQEQLVREVFEA
NT seq
3513 nt
NT seq
+upstream
nt +downstream
nt
gtgaagcccgccgccgcccccgctcaggccccggctccggccccggcccccgcggcgaag
gctcccgccccggccaagccggcgcagcccgcacaggcgcccgctcagcccgcggcgaag
cccgccccggccgaggcccccgagggcccggagctgatcacgctgcgcggcccggccgcc
gccgtcgccaagaacatgaacgcctccctggagctgccgaccgccacctcggtccgcgcc
gtcccggtgaagctgctgttcgacaaccgcatcgtcatcaacaaccacctgaagcgcgcc
cggggcgggaagatctccttcacgcacctgatcggcttcgcgatggtgcaggccatcaag
gccatgccgtcgatgaactggtcgttcggcgagaaggacggcaagccgaccctcgtcaag
ccgccgcacgtcaacctcggcctggccatcgacctggtcaagccgaacggtgaccgccag
ctcgtcgtggccgccatcaagaaggccgagacgctgaacttcttcgagttctggcaggcc
tacgaggacatcgtccgccgcgcccgcgacggcaagctgacgatggacgacttcaccggc
gtcacggtctccctgaccaaccccggcggcctcggcaccgtccactccgtgccgcgcctc
atgcccggccagtccgtgatcatgggcgtcggctccatggactacccggcggagttccag
ggcaccagccaggacaccctgaacaagctcggcatctccaaggtcatgacgctcacgtcg
acctacgaccaccgggtcatccagggcgccgcctccggcgagttcctccgccaggtcgcc
aacctgctgctcggcgagaacggcttctacgacggcatcttcgaggcgctgcgcatcccc
tacgagccggtccgctggctcaaggacatcgacgcctcccacgacgacgacgtcaccaag
gccgcccgcgtcttcgagctgatccactcctaccgggtccgcggtcacgtcatggccgac
accgacccgctggagtacaagcagcgcaagcaccccgacctggacatcaccgagcacggg
ctcacgctgtgggacctggagcgcgacttcgcggtcggcggcttcgccggcaagtcgatg
atgaagctgcgcgacatcctcggcgtcctgcgcgactcgtactgccgcaccaccggcatc
gagttcatgcacatccaggaccccaagcagcgcaagtggatccaggaccgcgtcgagcgc
ccgcacgccaagatggagcgtgaggagcagctgcggatcctgcgccggctgaacgccgcg
gaggccttcgagacgttcctccagacgaagtacgtcggccagaagcgattctcgctggag
ggcggcgagtccgtcatcccgctgctcgacgcggtgatcgactccgccgccgagtcccgc
ctggacgaggtcgtcatcggcatggcccaccgtggccgcctgaacgtcctcgccaacatc
gtcggcaagtcctacgcgcagatcttccgcgagttcgagggcaacctcgacccgaagtcg
atgcacggctccggtgacgtcaagtaccacctgggcgccgagggcaccttcaccggcctg
gacggcgagcagatcaaggtctcgctggccgccaacccctcccacctggagacggtcgac
ccggtcatcgagggcatcgcccgcgccaagcaggacatcatcaacaagggcgggacggac
ttcaccgtgctgcccgtcgcgctgcacggcgacgcggccttcgcgggccagggcgtggtg
gccgagaccctgaacatgtcgcagctgcgcggctaccgcaccggcggcacggtccacatc
gtcatcaacaaccaggtcggcttcaccgcggcccccgagtcctcgcgttcctccatgtac
gcgacggacgtggcccgcatgatcgaggccccgatcttccacgtgaacggcgacgacccg
gaggccgtggtccgcgtcgcgcggctggccttcgagttccgccaggcgttcaacaaggac
gtggtgatcgacctcatctgctaccgccgccgcggtcacaacgagtcggacaacccggcc
ttcacccagccgctgatgtacgacctgatcgacaagaagcgctcggtgcgcaagctgtac
accgagtccctgatcggtcgcggcgacatcaccctggaagaggccgagcaggccctccag
gactaccagggtcagctggagaaggtcttcacggaggtccgcgaggccgtcaccacccag
caggccaccggccccgtgtcggacccgcaggcggagttcccggtcgccgtgaacaccgcg
atctccacggaggtcgtcaagcgcatcgccgagtcccaggtcaacatcccggactccttc
cacgtgcacccgcgtctgctgccccagttgcagcgccgggcggcgatggtcgaggacggc
acgatcgactggggcatgggcgagaccctcgcggtcggctccctgctgctggagggcacc
ccggtccggctgtccggccaggactcccagcgcggcaccttcggccagcgccacgcggtc
ctcatcgaccgcgagacgggcgaggagtacaccccgctccagtacctcgccgaagaccag
gcgcgctacaacgtctacaactccctgctgtccgagtacgcggtcatgggcttcgagtac
ggctactcgctggcccgccccgacgcgctcgtgatgtgggaggcgcagttcggtgacttc
gtcaacggcgcccagacggtcgtcgacgagtacatctcggcggcggagcagaagtggggc
cagacgtccggcgtcaccctgctcctgccgcacggctacgagggccagggcccggaccac
tcctcggcccgggtcgagcggttcctccagctctgcgcccagaacaacatgacggtcgcc
atgccgaccctgccgtcgaactacttccacctcctgcggtggcaggtgcacaacccgcac
cacaagccgctggtggtcttcaccccgaagtcgatgctccgcctgaaggccgccgcgtcg
aagacggaggagttcacgtcgggtcagttccgtcccgtcatcggggacacggcggcggac
ccggccgcggtccgcaaggtcgtgttcgtggccggcaagctgtactacgaccttgaggcc
gagcggcagaagcggggcgtgacggacaccgcgatcatccgcatcgagcggctgtacccg
ctgccgggtgcggagatccaggccgaggtcaacaagtacccgaacgccgagaagtacctg
tgggcgcaggaggagccggcgaaccagggtgcgtggccgttcatcgcgctcaacctgatc
gaccacctggacctggcggtcggcgcggacgtcccgcacggcgagcgcctgcggcgcatc
tcgcgtccgcactcctcgtccccggcggtcggctccgcgaagcggcaccaggcggagcag
gagcagttggtgcgtgaggtgttcgaggcgtaa
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