Streptomyces hygroscopicus subsp. jinggangensis TL01: SHJGH_6432
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Entry
SHJGH_6432 CDS
T02531
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sho
Streptomyces hygroscopicus subsp. jinggangensis TL01
Pathway
sho00470
D-Amino acid metabolism
sho00550
Peptidoglycan biosynthesis
sho01100
Metabolic pathways
sho01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sho00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SHJGH_6432
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SHJGH_6432
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SHJGH_6432
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sho01011
]
SHJGH_6432
Enzymes [BR:
sho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SHJGH_6432
Peptidoglycan biosynthesis and degradation proteins [BR:
sho01011
]
Precursor biosynthesis
Amino acid ligase
SHJGH_6432
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AGF66095
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Position
7281528..7282685
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AA seq
385 aa
AA seq
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MSTENLPQSPEQPQRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTKYDVLPIGITADG
RWALTADEPERMVITDRRTPSVAELAESDEGGVVLPVDPANREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRIFTSYGLKVGPYLV
IRPREWARDESAARKKIIDFAGEHGWPLFVKPARAGSSIGITKVEDLSGLDEAIAEAQAH
DPKILVEAAVRGREIECGVLEFEDGPRASVPAEIPPPDAHAYYDFEAKYIDSTPGVVPAP
LTEEQTAEVRWLAVEAFEATSCEGLVRADFFLTEDGEFVINEVNTMPGFTPISMYPQMWQ
ASGISYPELVDRLVQAALRRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaaccttccccagagccctgagcagccgcagcgcaagccgcgcgtggcc
gtcgtgttcggcgggcgcagttccgaacacgggatctccgtggtcaccgccggcgccgtc
ctcaaggccatcgaccggacgaagtacgacgtcctgccgatcggcatcaccgcggacggc
cgctgggcgctgacggccgacgagccggagcggatggtcatcaccgaccgccgcaccccc
agcgtggcggagcttgcggagtcggacgagggcggcgtggtgctccccgtcgacccggcg
aaccgcgaggtcgtctacagcgagcccggctccgtgcccaaggcgctcggcgaggtcgac
gtggtcttcccggtgctccacggcccctacggcgaggacggcaccctccagggcctgctg
gagctgtccggagtgccctacgtgggctccggcgtgctcgcctcggccgtcggccaggac
aaggagtacatgaagcggatcttcacctcctacgggctcaaggtcggcccgtacctggtg
atccggccccgcgagtgggcccgggacgagtccgccgcccgcaagaagatcatcgacttc
gccggcgagcacggctggccgctgttcgtgaagcccgcgcgcgcgggctcgtccatcggc
atcacgaaggtcgaggacctgtccggcctggacgaggcgatcgccgaggcgcaggcccac
gacccgaagatcctggtcgaggcggccgtacgcggccgtgagatcgagtgcggcgtcctg
gagttcgaggacggcccgcgcgcctccgtcccggccgagatcccgccgccggacgcgcac
gcgtactacgacttcgaggccaagtacatcgactccacgcccggcgtcgtcccggccccg
ctcaccgaggagcagaccgccgaggtgcgctggctcgccgtcgaggcgttcgaggcgacc
tcctgcgagggcctggtccgcgcggacttcttcctcaccgaggacggcgagttcgtgatc
aacgaggtcaacacgatgcccggcttcacgccgatctcgatgtacccgcagatgtggcag
gcgagcgggatcagctaccccgagctggtggaccgcctggtgcaggcggcgctgcgccgc
ccgacggggctgcgctga
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