Sarcophilus harrisii (Tasmanian devil): 100913337 Help Entry 100913337         CDS       T02286                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism shr  Sarcophilus harrisii (Tasmanian devil) Pathway shr01521   EGFR tyrosine kinase inhibitor resistance shr04010   MAPK signaling pathway shr04012   ErbB signaling pathway shr04014   Ras signaling pathway shr04015   Rap1 signaling pathway shr04020   Calcium signaling pathway shr04066   HIF-1 signaling pathway shr04070   Phosphatidylinositol signaling system shr04071   Sphingolipid signaling pathway shr04072   Phospholipase D signaling pathway shr04150   mTOR signaling pathway shr04151   PI3K-Akt signaling pathway shr04261   Adrenergic signaling in cardiomyocytes shr04270   Vascular smooth muscle contraction shr04310   Wnt signaling pathway shr04360   Axon guidance shr04370   VEGF signaling pathway shr04510   Focal adhesion shr04540   Gap junction shr04613   Neutrophil extracellular trap formation shr04650   Natural killer cell mediated cytotoxicity shr04664   Fc epsilon RI signaling pathway shr04666   Fc gamma R-mediated phagocytosis shr04670   Leukocyte transendothelial migration shr04713   Circadian entrainment shr04720   Long-term potentiation shr04723   Retrograde endocannabinoid signaling shr04724   Glutamatergic synapse shr04725   Cholinergic synapse shr04726   Serotonergic synapse shr04727   GABAergic synapse shr04728   Dopaminergic synapse shr04730   Long-term depression shr04750   Inflammatory mediator regulation of TRP channels shr04911   Insulin secretion shr04912   GnRH signaling pathway shr04916   Melanogenesis shr04918   Thyroid hormone synthesis shr04919   Thyroid hormone signaling pathway shr04921   Oxytocin signaling pathway shr04925   Aldosterone synthesis and secretion shr04926   Relaxin signaling pathway shr04928   Parathyroid hormone synthesis, secretion and action shr04929   GnRH secretion shr04933   AGE-RAGE signaling pathway in diabetic complications shr04935   Growth hormone synthesis, secretion and action shr04960   Aldosterone-regulated sodium reabsorption shr04961   Endocrine and other factor-regulated calcium reabsorption shr04970   Salivary secretion shr04971   Gastric acid secretion shr04972   Pancreatic secretion shr05017   Spinocerebellar ataxia shr05022   Pathways of neurodegeneration - multiple diseases shr05031   Amphetamine addiction shr05032   Morphine addiction shr05143   African trypanosomiasis shr05146   Amoebiasis shr05161   Hepatitis B shr05163   Human cytomegalovirus infection shr05164   Influenza A shr05170   Human immunodeficiency virus 1 infection shr05171   Coronavirus disease - COVID-19 shr05200   Pathways in cancer shr05205   Proteoglycans in cancer shr05206   MicroRNAs in cancer shr05207   Chemical carcinogenesis - receptor activation shr05214   Glioma shr05223   Non-small cell lung cancer shr05225   Hepatocellular carcinoma shr05231   Choline metabolism in cancer shr05415   Diabetic cardiomyopathy shr05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:shr00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     100913337 (PRKCA)    04012 ErbB signaling pathway     100913337 (PRKCA)    04014 Ras signaling pathway     100913337 (PRKCA)    04015 Rap1 signaling pathway     100913337 (PRKCA)    04310 Wnt signaling pathway     100913337 (PRKCA)    04370 VEGF signaling pathway     100913337 (PRKCA)    04066 HIF-1 signaling pathway     100913337 (PRKCA)    04020 Calcium signaling pathway     100913337 (PRKCA)    04070 Phosphatidylinositol signaling system     100913337 (PRKCA)    04072 Phospholipase D signaling pathway     100913337 (PRKCA)    04071 Sphingolipid signaling pathway     100913337 (PRKCA)    04151 PI3K-Akt signaling pathway     100913337 (PRKCA)    04150 mTOR signaling pathway     100913337 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     100913337 (PRKCA)    04540 Gap junction     100913337 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     100913337 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     100913337 (PRKCA)    04664 Fc epsilon RI signaling pathway     100913337 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     100913337 (PRKCA)    04670 Leukocyte transendothelial migration     100913337 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     100913337 (PRKCA)    04929 GnRH secretion     100913337 (PRKCA)    04912 GnRH signaling pathway     100913337 (PRKCA)    04921 Oxytocin signaling pathway     100913337 (PRKCA)    04926 Relaxin signaling pathway     100913337 (PRKCA)    04935 Growth hormone synthesis, secretion and action     100913337 (PRKCA)    04918 Thyroid hormone synthesis     100913337 (PRKCA)    04919 Thyroid hormone signaling pathway     100913337 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     100913337 (PRKCA)    04916 Melanogenesis     100913337 (PRKCA)    04925 Aldosterone synthesis and secretion     100913337 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     100913337 (PRKCA)    04270 Vascular smooth muscle contraction     100913337 (PRKCA)   09154 Digestive system    04970 Salivary secretion     100913337 (PRKCA)    04971 Gastric acid secretion     100913337 (PRKCA)    04972 Pancreatic secretion     100913337 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     100913337 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     100913337 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     100913337 (PRKCA)    04727 GABAergic synapse     100913337 (PRKCA)    04725 Cholinergic synapse     100913337 (PRKCA)    04728 Dopaminergic synapse     100913337 (PRKCA)    04726 Serotonergic synapse     100913337 (PRKCA)    04720 Long-term potentiation     100913337 (PRKCA)    04730 Long-term depression     100913337 (PRKCA)    04723 Retrograde endocannabinoid signaling     100913337 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     100913337 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     100913337 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     100913337 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     100913337 (PRKCA)    05206 MicroRNAs in cancer     100913337 (PRKCA)    05205 Proteoglycans in cancer     100913337 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     100913337 (PRKCA)    05231 Choline metabolism in cancer     100913337 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     100913337 (PRKCA)    05214 Glioma     100913337 (PRKCA)    05223 Non-small cell lung cancer     100913337 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     100913337 (PRKCA)    05161 Hepatitis B     100913337 (PRKCA)    05171 Coronavirus disease - COVID-19     100913337 (PRKCA)    05164 Influenza A     100913337 (PRKCA)    05163 Human cytomegalovirus infection     100913337 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     100913337 (PRKCA)    05143 African trypanosomiasis     100913337 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     100913337 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     100913337 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     100913337 (PRKCA)    05032 Morphine addiction     100913337 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     100913337 (PRKCA)    05415 Diabetic cardiomyopathy     100913337 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     100913337 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     100913337 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:shr01001]     100913337 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:shr04131]     100913337 (PRKCA) Enzymes [BR:shr01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      100913337 (PRKCA) Protein kinases [BR:shr01001]  Serine/threonine kinases: AGC group   PKC family [OT]    100913337 (PRKCA) Membrane trafficking [BR:shr04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     100913337 (PRKCA) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 C1_2 DUF4656 Motif Other DBs NCBI-GeneID:  100913337 NCBI-ProteinID:  XP_031821528 Ensembl:  ENSSHAG00000009585 LinkDB All DBs Position 4:complement(309486028..309952528) Genome browser AA seq 674 aa AA seqDB search MADVFPANDSTTSQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLLHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTAEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPTDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNME LRQKFEKAKLGPAGNKVISPSDDRKSNVPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADR KGTEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVME YVNGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKQGIIYRDLKLDNVMLDSEGHIK IADFGMCKEHMLDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPF DGEDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGSEGERDIREHAFFR RIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQADFEGFSY VNPQFVHPILQSAV NT seq 2025 nt NT seq  +upstreamnt  +downstreamnt atggccgacgttttcccggccaatgactctaccacgtctcaggacgtggccaaccgtttt gcccgcaaaggggcgctaaggcagaagaacgtgcatgaagtcaaggaccacaaattcatc gcccgcttcttcaagcagcccaccttctgcagccattgcactgacttcatctgggggttt gggaaacaaggtttccagtgccaagtttgctgttttgttgttcacaagaggtgccatgaa tttgtcactttctcttgtccgggtgcagataaagggcctgacactgatgaccccagaagt aagcacaagtttaaaatccacacatatggaagccctactttttgtgatcactgtggctca ctgctttatggacttctacatcaaggaatgaaatgtgacacctgtgatatgaatgttcac aaacaatgtgtaataaatgttccaagcctctgtggaatggaccatacagaaaaaagagga cgaatttatctgaaagcagaagtcacagctgaaaaactacatgtcacagtacgagatgca aaaaacttaatccctatggatccaaatggactttcagatccctatgtgaagctgaaactt atccctgaccctaagaatgaaagtaaacaaaaaaccaaaacaatccgctccacactaaac ccacagtggaatgagtcattcacattcaaattaaaacctacagataaagatagacggtta tctgttgagatctgggactgggatcgaacaacaagaaatgattttatgggttcactttca tttggggtatccgagcttatgaaaatgccggcaagtggatggtataagttgcttaatcaa gaagaaggtgaatactacaatgtgcccattccagaaggggatgaagaaggaaatatggaa ctgagacagaagtttgaaaaagccaagcttggccctgctggtaacaaggtgatcagtcca tcagatgacagaaaatccaatgtaccatccaacaaccttgacagagtgaaacttacagac tttaattttctcatggtcctggggaagggtagttttggaaaggtgatgttggctgaccgg aagggaacagaagaactatatgccatcaaaattttgaaaaaagatgtggtgatacaagat gatgatgttgaatgcacaatggtagagaagagagtattagcactcctagacaagcctcct ttcttaacacaactacactcctgtttccagacagtggatcgtctttattttgtcatggaa tatgtcaatggtggagatctcatgtaccacattcagcaagtaggaaaatttaaggagcca caggcagtgttctatgcagcagagatttcaattggattattcttccttcataaacaaggg atcatttatagagatttgaaattagacaatgtcatgttggattcagaaggacacatcaag attgctgattttggaatgtgtaaagagcatatgttagatggagtcacaaccaggaccttc tgtggaactccagattacattgctccagagatcattgcttatcagccgtatggaaaatct gtggactggtgggcctatggtgtcctcttatatgaaatgttagctggacagcctccattt gatggtgaagatgaggatgaactcttccagtccataatggaacacaatgtttcctatcca aaatcattgtccaaggaggctgtttccatctgcaaaggactaatgacaaagcaccctgca aaacgcctgggctgtggatctgagggagaaagggacatcagagaacatgcatttttcaga agaattgactgggagaaattggagaacagagagatccaaccaccatttaaacctaaagtg tgtggcaaaggagcagaaaactttgacaaattctttacccgaggacagccagtgttaaca ccacctgatcaactggtcattgctaacatagaccaagccgattttgaagggttctcttat gtcaacccacagtttgtgcaccccatcttgcagagtgcggtatga

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