Sarcophilus harrisii (Tasmanian devil): 100916991
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Entry
100916991 CDS
T02286
Symbol
JAK1
Name
(RefSeq) tyrosine-protein kinase JAK1 isoform X1
KO
K11217
Janus kinase 1 [EC:
2.7.10.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr04151
PI3K-Akt signaling pathway
shr04217
Necroptosis
shr04380
Osteoclast differentiation
shr04550
Signaling pathways regulating pluripotency of stem cells
shr04620
Toll-like receptor signaling pathway
shr04621
NOD-like receptor signaling pathway
shr04630
JAK-STAT signaling pathway
shr04658
Th1 and Th2 cell differentiation
shr04659
Th17 cell differentiation
shr05140
Leishmaniasis
shr05145
Toxoplasmosis
shr05152
Tuberculosis
shr05160
Hepatitis C
shr05161
Hepatitis B
shr05162
Measles
shr05163
Human cytomegalovirus infection
shr05164
Influenza A
shr05165
Human papillomavirus infection
shr05166
Human T-cell leukemia virus 1 infection
shr05167
Kaposi sarcoma-associated herpesvirus infection
shr05168
Herpes simplex virus 1 infection
shr05169
Epstein-Barr virus infection
shr05171
Coronavirus disease - COVID-19
shr05200
Pathways in cancer
shr05203
Viral carcinogenesis
shr05212
Pancreatic cancer
shr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100916991 (JAK1)
04151 PI3K-Akt signaling pathway
100916991 (JAK1)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100916991 (JAK1)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100916991 (JAK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
100916991 (JAK1)
04621 NOD-like receptor signaling pathway
100916991 (JAK1)
04658 Th1 and Th2 cell differentiation
100916991 (JAK1)
04659 Th17 cell differentiation
100916991 (JAK1)
09158 Development and regeneration
04380 Osteoclast differentiation
100916991 (JAK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100916991 (JAK1)
05203 Viral carcinogenesis
100916991 (JAK1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100916991 (JAK1)
09162 Cancer: specific types
05212 Pancreatic cancer
100916991 (JAK1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100916991 (JAK1)
05161 Hepatitis B
100916991 (JAK1)
05160 Hepatitis C
100916991 (JAK1)
05171 Coronavirus disease - COVID-19
100916991 (JAK1)
05164 Influenza A
100916991 (JAK1)
05162 Measles
100916991 (JAK1)
05168 Herpes simplex virus 1 infection
100916991 (JAK1)
05163 Human cytomegalovirus infection
100916991 (JAK1)
05167 Kaposi sarcoma-associated herpesvirus infection
100916991 (JAK1)
05169 Epstein-Barr virus infection
100916991 (JAK1)
05165 Human papillomavirus infection
100916991 (JAK1)
09171 Infectious disease: bacterial
05152 Tuberculosis
100916991 (JAK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100916991 (JAK1)
05140 Leishmaniasis
100916991 (JAK1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100916991 (JAK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100916991 (JAK1)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100916991 (JAK1)
Protein kinases [BR:
shr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100916991 (JAK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
ABC1
RIO1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
100916991
NCBI-ProteinID:
XP_031824829
Ensembl:
ENSSHAG00000014365
LinkDB
All DBs
Position
4:12223352..12359533
Genome browser
AA seq
1153 aa
AA seq
DB search
MQYLNFKEDCNAMAFCAKMRSYKKNEVNLDVLEPGVEVAFYLPDRKPLHLLNGEYTVEDL
CIRAAQECSISPLCHNLFALYDEKAKLWYAPNHCIKIEEKTSLRLHYRMRFYFTNWHGTN
ENEQSVWRHSPKKQKNGYERRRVLDATPLLDANSLEYLFAQGQYDLVKCLAPVRDPKTDQ
EVHEIENECLGMAVLAISHYAMMNNIQLPDLPKDVSYKRYIPETLNKTIRQRNLLTRLRI
NNVFKDFLKEFNNKTICDSSVTPHDLKVKYLSTLETLTKHYGAEIFETSLLLISSENEMN
KLNSKDCGNVISYEVMVTGNLGIQWRQKPNVVPVEKEKNKLKRKKQDNRHRKEEEKNKAR
EEWNSFSYFPEITHVVIKESMVSINKQDNKKMELSLSSHEEALSFVSLVDGYFRLTADAH
HYLCTDVAPPLIVHNIENGCHGPICTEYAINKLRQEGSEEGMYVLRWSCTDFDNILMTVT
CFEKSEQMLTSQKQYKNFQIEVKKGKYSLHGSDRVFPSLKGLMDHLKKQILKTDNISFVL
KKCCQPKPREISNLLVATKKAQECQPVYTMSQLSFHRILKEDIIQGEHMGRGTRTQIYSG
TLDYKDDEGSSDEKKMKVILKVLDPSHRDISLAFFEAASMMRQVSHKHIVYLYGVCVRDV
ENIMVEEYMEFGPLDLFMHRKSELLTTPWKFKVAKQLASALSYLEDKDLVHGNVCAKNVL
LAREGLDGECSPFIKLSDPSIPITVLSRQECVERIPWIAPECVDDSKNLSVAADKWSFGT
TLWEICYNGEIPLKDKTLAEKERFYEGRVMPVTPSCKELADLMTQCMNYDPSQRPFFRAI
MRDINRLEEQNPDILSEKQPTTEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNT
GEQVAVKSLKPESGGNQIADLKKEIEILKNLYHENIVKYKGICTEDGGNRIKLIMEFLPS
GSLKEYLPRNKNKINLKQQLKYAVQICKGMDYLGSCQYVHRDLAARNVLVENEHRVKIGD
FGLTKAIETDKEYYTVKDDRDSPVFWYAPECLVQCKFYIASDVWSFGVTLHELLTYCDSE
SSPMAMFLKMIGPTQGQMTVTRLVRALKEGKRLQCPPNCPEEVYQLMKKCWEYQPNNRTS
FQNLIRGFEALIK
NT seq
3462 nt
NT seq
+upstream
nt +downstream
nt
atgcagtatctaaatttcaaggaagactgcaatgcgatggcgttctgtgcaaaaatgagg
agctacaaaaagaacgaggtgaacctggatgtgctggagcccggcgtggaggtggccttc
tacctgcccgacaggaagcccctccacttgctcaacggcgagtacacggtggaagatctg
tgcatcagagccgcccaggagtgctccatctcccctctgtgccacaacctgttcgccctg
tacgatgagaaggccaagctctggtacgccccaaatcactgcatcaagatcgaagagaaa
acctcactgcggctgcactatcgcatgaggttctatttcaccaactggcatgggaccaat
gagaacgagcagtcggtgtggagacactccccaaagaagcagaaaaatggttatgaaaga
aggcgggtcctggatgctacccccctcctggatgccaactcactggagtatctgtttgct
cagggacaatatgacttggtgaaatgcttggctcctgtacgagacccgaagaccgaccag
gaagtgcacgagatcgaaaatgaatgtctggggatggcagtgctggccatatcccattat
gccatgatgaataacatccagcttccggatctgcccaaggatgtcagttacaagcgatat
attccagaaacactgaacaagaccatcagacaaaggaatctcttaaccagattgcgaatc
aataacgttttcaaggatttccttaaggaatttaacaacaagaccatctgtgacagcagc
gtgactccccatgacctgaaggtgaaatacctgtccaccttggagacgctgaccaaacat
tacggagctgaaattttcgagacttcactcttgttgatttcgtctgaaaatgaaatgaat
aaattaaactcaaaggactgtgggaacgtcataagttatgaagtgatggtgactgggaat
ctcggaatacaatggaggcaaaaaccaaatgtggttcctgttgagaaagagaaaaataag
ctgaagaggaagaaacaggacaacagacacaggaaagaagaggagaaaaacaaagcccga
gaggaatggaacagcttctcttacttccccgaaatcacccatgtcgtcatcaaggaatcc
atggtcagcattaacaagcaggacaacaaaaagatggagttaagcctgtcctcccacgag
gaagccttgtctttcgtgtctctggtggacgggtatttccggctcacggcggacgcccat
cattacctctgcacggatgtcgcccctccactgattgtgcacaacatcgagaatggctgt
catggtccaatctgcactgagtatgcaatcaacaaactgaggcaagaaggaagcgaggaa
ggcatgtatgttctgcgctggagctgcacagactttgacaacatcctcatgaccgtgacc
tgcttcgagaaatcggagcagatgctcacgagccagaaacagtacaagaacttccagatt
gaggtgaagaagggcaaatactccctgcacggctccgaccgtgtgttcccctctctcaaa
ggcctcatggaccatctcaaaaagcagatcctgaaaacggacaacatcagcttcgtccta
aagaaatgctgccagcccaaaccgagagaaatctctaacctgctggtggccaccaagaag
gcccaggagtgccagccagtctacaccatgagccagctgagtttccatcggattctcaag
gaagacatcatccagggagagcacatgggacgaggcactcgcacccagatctactcgggg
accctggattacaaggacgatgaaggcagctctgatgagaaaaaaatgaaagtcatcctc
aaggtcttggaccccagtcacagggacatttctctggctttcttcgaggcagccagcatg
atgaggcaggtgtcccacaagcacatcgtgtacctctacggcgtctgcgtccgtgacgtg
gaaaatatcatggtggaggagtacatggagttcgggcccctggacctcttcatgcatcgg
aaaagcgagctgctcaccacgccctggaagtttaaggtggccaaacagctggccagcgca
ctgagttacttggaggacaaagatttagtccacggcaacgtgtgtgccaagaacgtgctg
ttggccagagagggcctggacggggagtgtagccccttcatcaagctcagcgatcccagc
atccccatcaccgtgctctcccgccaggaatgtgtggaacggattccatggattgcccca
gagtgtgtggatgactccaagaacctgagcgtggccgctgataaatggagtttcggcaca
accctctgggagatctgctacaatggagagatccccctgaaagataagactctagcagag
aaagaaagattttatgaaggtcgagttatgccggtcacgccttcatgcaaggagctggcc
gacctgatgactcagtgcatgaactacgaccctagtcagagacccttcttccgagccatc
atgagagacatcaacaggctagaagaacagaacccagatatcctttcagagaaacagcca
acaactgaggtagatcccactcattttgaaaaacggttcttgaagaggatccgggactta
ggagagggtcacttcgggaaagttgaactgtgcaggtacgacccggaaggggacaacaca
ggggaacaggtcgcagtgaagtccctgaagccagagagtgggggcaaccagatcgccgac
ctgaagaaggagatcgaaatcttgaagaacctctatcacgaaaacattgtgaaatacaag
gggatctgtacagaggatggaggaaataggattaagctcatcatggagttcctgccttct
gggagccttaaggaatatcttcccaggaataagaacaaaatcaacctcaaacagcagctg
aagtacgcagttcagatctgtaaggggatggactatctgggatcctgtcagtatgtccac
cgagatcttgcagcaagaaatgtccttgttgagaatgagcaccgggtgaagattggagat
tttggcttaacgaaagccattgaaacagacaaggagtactacacggtgaaagatgatcga
gacagtcccgtcttctggtatgccccagaatgtttagttcaatgcaaattttatatcgcc
tctgacgtctggtcattcggggtcacgttacatgaactgctcacctactgcgattcagaa
tccagtcccatggcgatgttcttgaagatgatcggcccaactcaaggccagatgaccgtc
acccggcttgtgagagcattaaaggaagggaaacgtttgcagtgcccacccaattgccca
gaagaggtttaccagctaatgaagaaatgctgggagtatcagccaaacaatcggacatct
tttcagaacctcatccggggatttgaagcacttataaaataa
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integrated database retrieval system
