Sarcophilus harrisii (Tasmanian devil): 100920108
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Entry
100920108 CDS
T02286
Symbol
JAK3
Name
(RefSeq) tyrosine-protein kinase JAK3
KO
K11218
Janus kinase 3 [EC:
2.7.10.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr04062
Chemokine signaling pathway
shr04151
PI3K-Akt signaling pathway
shr04217
Necroptosis
shr04550
Signaling pathways regulating pluripotency of stem cells
shr04630
JAK-STAT signaling pathway
shr04658
Th1 and Th2 cell differentiation
shr04659
Th17 cell differentiation
shr05161
Hepatitis B
shr05162
Measles
shr05166
Human T-cell leukemia virus 1 infection
shr05169
Epstein-Barr virus infection
shr05200
Pathways in cancer
shr05203
Viral carcinogenesis
shr05223
Non-small cell lung cancer
shr05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100920108 (JAK3)
04151 PI3K-Akt signaling pathway
100920108 (JAK3)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100920108 (JAK3)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100920108 (JAK3)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100920108 (JAK3)
04659 Th17 cell differentiation
100920108 (JAK3)
04062 Chemokine signaling pathway
100920108 (JAK3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100920108 (JAK3)
05203 Viral carcinogenesis
100920108 (JAK3)
09162 Cancer: specific types
05223 Non-small cell lung cancer
100920108 (JAK3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100920108 (JAK3)
05161 Hepatitis B
100920108 (JAK3)
05162 Measles
100920108 (JAK3)
05169 Epstein-Barr virus infection
100920108 (JAK3)
09163 Immune disease
05340 Primary immunodeficiency
100920108 (JAK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100920108 (JAK3)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100920108 (JAK3)
Protein kinases [BR:
shr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100920108 (JAK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
FERM_C_FAK1
SH2
ABC1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
100920108
NCBI-ProteinID:
XP_003762809
Ensembl:
ENSSHAG00000004978
UniProt:
G3VR92
LinkDB
All DBs
Position
1:669207329..669244338
Genome browser
AA seq
1110 aa
AA seq
DB search
MAPLGEETPLIEQRSYSLSSSESGSLQVFLCPQSSGSPQILTFSFGEYSAEELCVKAAKA
CGILPVCHALFALATEDLSCWFPPNHVFTVEDSTIQVLLYRIRFFFPNWFGLEKCYRFGL
QKDRANAILDLPVLKYLFAQSRSDFINGRMNLTLNLKEQGECLSLAVLDLTRMAQEQGIR
PKEILRRISYKTCIPGSFRRLIQSLSFMTRKRYRQMVSRALQSVASCQADVYSIMLKYLM
DLERLKPTRNLETFTGRAPGATSGQDPRCLIHVAGDSGISWTPAGSESPQPFCDFPEIVD
IGIKQACRDGHLSENRLVTVTKTDNRILEVEFPTLREALSFISLVDGYYRLTTDAHHYFC
KEVAPPQLLENIENQCHGPIKSEFAVNKLKMGGSVPGSYVLRQSPQDFDSFLLTVCIQTP
LGPDYKGCLIHRDLSGNLFLSGLSQPHSSLRQLLESSWSCGLLVDGTALSLSCCYPPRPK
EKSNLIIVRRDCNQLPPSPALAAAQAWPHPQRQLSQMMFHKIPPDSLEWHENLGHGSFTK
IYRGSRLDNVDGETHKIEVLLKVMDSTHQNCIESFLEAASVMSQVSHQHLVLLHGVCMAG
DSIMVQEFVRWGALDTHLRKCGPLVPASWKLQVAKQLSYALNYLEDKGIIHGNISSKKVL
LAREGAGGSPPFIKLSDPGVSPTVLTKEMLTDRIPWVAPECLWDAKLLSLESDKWSFGAT
LWEIFSGGTMPLSTLEPAKKLQFYKEKQQLPALKWTELATLIGQCMEYTPHLRPSFRAII
RDLNSLITSDYELLSDLSPSAVAARDGLWSSTHLMAGQDPTLFEERHLKYISLLGKGNFG
SVELCRYDPLGDNTGALVAVKQLQNSGPQQLRDFQREVQILKALHSDFIVKYRGVCYGPG
RQSLRLVMEYLPNGCLRDYLQRHRAHLDPCFLLLYASQICKGMEYLGSQRYVHRDLANRN
ILVESESHVKIGDFGLAKLLPQDKEYYVVREPGQSPIFWYAPESLSDNIFSRESDVWSFG
VVLYELYTYSDKIHSPSEEFFRMMACDRSMPILCHLLDLLTEGKRLPTPPGCPGEVREIM
RNCWAYNPKDRPSFCALGPRLDALWAGRRG
NT seq
3333 nt
NT seq
+upstream
nt +downstream
nt
atggcacctctgggtgaggagacccccctgattgaacagcggtcctacagcctgtcctcc
agtgagtctggctctctgcaagtgttcctgtgtccccagagctcagggtccccacagatc
ctcaccttctcctttggggaatactctgccgaagaactctgcgtgaaggctgccaaggcc
tgtgggatcctgcctgtatgccatgctctgtttgctctggccacggaagatctgtcctgc
tggttcccacccaaccacgtcttcacagtggaggattctaccatccaagtgctcctttac
aggatccgctttttctttcccaactggtttggcctggagaagtgttaccgttttggactg
cagaaggacagagccaatgctattctggacctcccagtccttaagtatctttttgctcag
tcccgaagtgacttcattaatgggaggatgaatctgacgctgaatctaaaggagcaggga
gagtgtctgagcttggcagtgttggacctgactcgcatggcacaggagcagggcatacgc
cccaaggagatcctcaggagaatcagctataagacctgtatcccaggaagcttcagacgt
ttgatccagagcctcagcttcatgactcgaaaacgttatcgtcagatggtttcccgagcc
ctgcagagcgtggcttcctgccaggcagatgtgtactccatcatgcttaaatacctcatg
gacctggagaggctgaaacccacccggaatctggagaccttcacgggtcgggcaccaggg
gctacatctggccaggacccccgctgtctcatccatgtggctggggacagcggtatctcc
tggacccctgcgggcagtgagagcccccagcctttctgcgatttccctgaaattgttgat
atcggcatcaagcaggcctgcagggacggtcatctcagtgagaaccggctggtcactgtt
accaagactgacaacaggatcctggaggttgaatttccaacactaagggaagcgctgtcc
tttatctctctggttgatggctactaccgactcaccaccgatgcccaccactacttctgc
aaagaggtggcccctccccagctcttggagaacattgaaaaccaatgccatggtcccatc
aagtcagagtttgctgtgaacaaactgaagatgggggggtctgttccagggtcctatgtc
cttcggcaaagcccacaggactttgacagcttcctcctcactgtctgtatccagacgccc
ctgggcccagactacaagggctgcctgatccatcgggatctgtcagggaacctcttcttg
tctgggctgagccagccccacagcagcctgcgtcagctcctggagtcctcctggagctgt
gggctccttgtagatgggactgctctgagcctcagctgctgctaccctcccaggcccaaa
gaaaagtccaacctgatcatagtaaggagggactgcaaccagttgcccccatccccagcc
ctagctgcagcccaagcctggccccacccccagcgccaactcagccaaatgatgttccac
aaaatcccccctgacagcttggagtggcatgagaacctgggccacggctccttcaccaag
atataccgtgggagccgcctggacaatgtggatggagagacccacaagatagaggttctg
ctcaaagttatggacagcacacaccagaactgcatcgagtccttcctggaggctgccagt
gtcatgagccaagtgtcccaccagcatctggtgctgctgcatggtgtctgcatggcggga
gacagtatcatggtgcaggagtttgtgaggtggggggcactggatacccatttacggaag
tgcggccctctggtccctgccagctggaagctccaagtggccaagcaactttcttatgcc
ctcaactatctggaagacaaaggcatcatccatggcaatatctcctccaagaaggtcctc
ctagcgagagagggggccgggggaagcccccccttcatcaaactcagtgatcctggagtc
agtcccaccgtgctgaccaaagagatgctcactgaccggatcccctgggtggcccctgag
tgtctatgggatgccaagctgctgagcctggagtctgacaaatggagctttggggcaaca
ctctgggagatattcagtgggggcaccatgcccctaagtaccctggagcctgccaagaaa
ctccagttctacaaagagaaacagcagctgccggccctaaaatggacagagctggccacc
ctgattggccagtgcatggagtacaccccccacttgcggccctccttccgagctatcatc
cgggatctcaatagcctcatcacctcagattatgagctcctctcagatctctcacccagt
gcagtggcggctcgggatggactctggagcagtactcacctgatggctggtcaggacccc
accctctttgaggagagacaccttaaatatatctccctgctgggcaagggaaattttggc
agtgtggaattgtgccgctatgacccactgggagataacactggagcattagtggccgtc
aagcagctacagaatagtggtccccagcagctgcgagacttccaacgggaggtgcagatt
ctgaaagctttacacagtgacttcatagtcaaataccgaggcgtatgctatggtccaggc
cgacagagtctgcgactcgttatggaatacctccccaatggctgcctccgggattacctg
cagcgtcaccgggcccacctagacccctgtttcctccttctctatgcttcccagatttgc
aaggggatggagtacctgggatctcagcgatatgttcacagggatttagccaacaggaat
atcttggtggagagtgagagccacgtaaagatcggagactttggtctagccaaacttctt
ccccaggacaaagaatactacgtggtcagagagcctggccagagccccatcttctggtat
gccccagagtccttatcagacaacattttctccagggagtcggatgtgtggagttttggt
gtggtcctctatgagctttatacgtatagtgacaaaatccacagcccttcagaggagttt
ttccgaatgatggcttgtgaccgttctatgcccatcctgtgccacctcctggatctgctc
acagagggcaagaggctgcccactcctcctggctgcccaggagaggttagagagatcatg
aggaactgctgggcttacaaccccaaggaccggccctccttctgtgccctgggcccccga
cttgatgctttgtgggctgggcgaagagggtag
DBGET
integrated database retrieval system
