KEGG   Sarcophilus harrisii (Tasmanian devil): 100926799Help
Entry
100926799         CDS       T02286                                 

Gene name
HK1
Definition
(RefSeq) hexokinase 1
  KO
K00844  
hexokinase [EC:2.7.1.1]
Organism
shr  Sarcophilus harrisii (Tasmanian devil)
Pathway
Glycolysis / Gluconeogenesis
Fructose and mannose metabolism
Galactose metabolism
Starch and sucrose metabolism
Amino sugar and nucleotide sugar metabolism
Neomycin, kanamycin and gentamicin biosynthesis
Metabolic pathways
Carbon metabolism
HIF-1 signaling pathway
Insulin signaling pathway
Type II diabetes mellitus
Carbohydrate digestion and absorption
Central carbon metabolism in cancer
Module
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
Nucleotide sugar biosynthesis, glucose => UDP-glucose
Brite
KEGG Orthology (KO) [BR:shr00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    100926799 (HK1)
   00051 Fructose and mannose metabolism
    100926799 (HK1)
   00052 Galactose metabolism
    100926799 (HK1)
   00500 Starch and sucrose metabolism
    100926799 (HK1)
   00520 Amino sugar and nucleotide sugar metabolism
    100926799 (HK1)
  Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    100926799 (HK1)
 Environmental Information Processing
  Signal transduction
   04066 HIF-1 signaling pathway
    100926799 (HK1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    100926799 (HK1)
  Digestive system
   04973 Carbohydrate digestion and absorption
    100926799 (HK1)
 Human Diseases
  Cancers
   05230 Central carbon metabolism in cancer
    100926799 (HK1)
  Endocrine and metabolic diseases
   04930 Type II diabetes mellitus
    100926799 (HK1)
Enzymes [BR:shr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.1  hexokinase
     100926799 (HK1)
Membrane trafficking [BR:shr04131]
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    100926799 (HK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
Ensembl: 
LinkDB All DBs
Position
1
AA seq 915 aa AA seqDB search
MTEDCEPIINPPLNGTKIDKYLYSMRLSDENLNEITKRFKKAMKNGLSRNYNITASVKML
PTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVSHEKHQTVQMESEVYDTPESIMIGSGS
QLFDHVAECLGDFMEKKNIKDKNLPVGFTFSFPCRQTKIDEGVLITWTKRFKASGVEGSD
VVQLLNKAIKKRGDYEANIVAVVNDTVGTMMTCGFDDQECEVGLIIGTGTNACYMEEMQH
IDMVEGDEGRMCINTEWGAFGDDGSLNEFRTEFDKEIDRGSLNPGKQLFEKMVSGMYMGE
LVRLIIVKMAKGGLLFEGRITPELLTKGKFETKHVSAIEKTKEGLQRAQEILSNLGLEPS
PEDCVSVQHVCAIVSHRSANMVAAMLAGILSRLKENKGVTRLRTTIGVDGTLYKFHPQYS
RRFNKTLRRLVPDCDVRFILSESGSGKGAAMVTAVAYRLAEQHRQMEEMLAPLKLTIEQL
NQVKNRMRVEMDLGLQKKTNESARVKMLPSFVCGTPDGTEHGDFLALDLGGTNFRVLLVK
IRSGKKRSVEMHNKIYAIPEEAMQGTGEELFDHIVSCISDFLDYMGIKGARLPLGFTFSF
PCRQTSLDGGILLTWTKGFNASNCEGHDVPTLLREAIKRREEFDLDVVALVNDTVGTMMT
CAYEEPTCEIGLIVGTGSNACYMEEMKNIEMVEGNEGRMCINMEWGAFGDNGCLEDIRTE
YDRIVDDYSLNAGRQRYEKMISGMYLGEIVRNILIDFTRKGFLFRGQISETLKTRGIFKT
KFLSQIESDRLALLQVRTILQDLGLNSTCDDSILVKMVCGVVSQRAAQLCGAGMAAVVEK
IKENRGLKTLNVAVGVDGTLYKLHPHFSRIMHQTVSKLAPNCNVKFLLSEDGSGKGAALI
SAVGVKLRDAKAKAS
NT seq 2748 nt NT seq  +upstreamnt  +downstreamnt
atgactgaagactgtgagccaataattaatcctcccttgaatggcactaagatcgacaag
tacctttattccatgcggctctcagatgaaaaccttaatgaaatcacaaaacgatttaaa
aaagctatgaaaaatggcctctccagaaattataatataactgcttcggtgaagatgctg
ccaacatttgtcagatccattcctgatggctcagaaaagggagatttcattgctctggat
ctcggtggatcctcctttcgaattctacgagtgcaagtgtctcatgagaaacatcagact
gttcaaatggagtcagaggtttatgatacacccgagagtataatgattggcagtggatcc
cagctttttgatcacgttgctgaatgcctgggtgacttcatggagaaaaagaatatcaaa
gataaaaatttacccgttggatttaccttttccttcccctgccgacagacgaaaattgac
gagggtgtcctgatcacctggaccaagcgctttaaagccagtggcgtggagggatctgat
gtggtccaactgctcaacaaagcaatcaaaaagcgaggggattacgaagccaacatcgtg
gctgttgtgaatgacaccgtggggacaatgatgacctgtggctttgatgaccaggagtgt
gaagtgggcttgatcattggtaccggaaccaacgcctgctacatggaggagatgcaacac
atcgacatggtggaaggggacgaagggcgcatgtgcatcaacacggagtggggggccttc
ggggatgatggcagcctcaatgaattccgcacagagtttgacaaggagatcgatcggggt
tccctcaatcctggaaagcaactgtttgagaagatggtcagcggcatgtacatgggggag
ctcgtcagactgattattgtgaagatggccaaagggggcctcctgtttgagggacggatc
acacctgagcttctcaccaaagggaaatttgaaaccaagcatgtgtcagccattgaaaaa
accaaggaaggcctccaaagagcccaagaaatcctgagtaacctcggcttggaaccatcc
cctgaagattgcgtctctgtccagcatgtgtgcgccatcgtgtctcatcgctcagccaac
atggtggctgccatgttagccggcatcctgtcccgcctgaaagaaaacaaaggggtgact
cggctgcggaccaccatcggtgtcgatgggaccctttacaagttccatccacagtattcc
cgtcgattcaacaagaccctgcggcgcttggtccccgactgcgacgtgcgcttcatcctc
tctgagagtgggagcggaaagggggctgccatggtgaccgctgtggcctatcggctggcc
gaacagcacaggcagatggaagaaatgctggcccccttaaagctcaccatcgagcagctc
aatcaagtgaagaacagaatgcgagtggagatggatctcggcctgcagaagaagaccaat
gaatcagccagagtgaaaatgctgccctcgtttgtctgcggcacccccgacgggacagaa
catggagacttcctggccttggaccttggcggcaccaactttcgggttctgttggtgaag
atccgcagcgggaagaagagaagtgttgaaatgcacaacaaaatctatgctatccctgag
gaagcgatgcagggaactggggaggagctctttgaccacatcgtcagctgtatttctgac
ttcctggactacatggggatcaagggggcccggttacccctcggcttcaccttttccttc
ccttgcagacagacaagcttggacgggggcatcttgctcacgtggacaaagggatttaac
gcgtccaactgtgaaggacatgacgtgcccaccttgctgagagaagccattaagaggaga
gaggaatttgacctggatgtcgtggctttggtcaatgacacagtgggcaccatgatgacc
tgtgcctacgaagagccaacgtgcgagatcggactcattgtagggaccggaagcaatgct
tgctacatggaagagatgaagaatatcgagatggtggaggggaatgaggggcggatgtgc
atcaacatggagtggggtgcttttggggacaacggatgcctggaagacattaggacagaa
tatgacagaattgtagacgattattccctcaatgctggcagacaaagatatgagaagatg
attagtggtatgtacttgggagaaatcgtccggaacattttaattgacttcactcgaaag
ggtttcctgttccgaggtcagatctctgagaccctgaaaacccggggaatctttaagacc
aagttcctgtcacagattgaaagtgataggttagccctgctccaagtccgaacgattctg
caggatctgggcctgaacagcacctgcgatgacagtatcctcgtcaagatggtctgtggg
gtggtgtcccagagggctgcccagctctgtggggctgggatggcggccgtcgtggaaaag
atcaaggagaatcggggcctgaagacccttaacgtggccgtgggagtcgatgggacgctt
tacaaactccatcctcacttctctcggatcatgcaccagacagtgagcaagctggccccc
aactgtaacgtgaaattcctcctctccgaagatggcagtgggaaaggagcagccctcatc
tcggccgttggggtgaagctccgggacgccaaggccaaggccagctaa

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