Sarcophilus harrisii (Tasmanian devil): 100927237
Help
Entry
100927237 CDS
T02286
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
shr
Sarcophilus harrisii (Tasmanian devil)
Pathway
shr01521
EGFR tyrosine kinase inhibitor resistance
shr04062
Chemokine signaling pathway
shr04148
Efferocytosis
shr04151
PI3K-Akt signaling pathway
shr04217
Necroptosis
shr04550
Signaling pathways regulating pluripotency of stem cells
shr04630
JAK-STAT signaling pathway
shr04658
Th1 and Th2 cell differentiation
shr04659
Th17 cell differentiation
shr04725
Cholinergic synapse
shr04917
Prolactin signaling pathway
shr04920
Adipocytokine signaling pathway
shr04933
AGE-RAGE signaling pathway in diabetic complications
shr04935
Growth hormone synthesis, secretion and action
shr05140
Leishmaniasis
shr05145
Toxoplasmosis
shr05152
Tuberculosis
shr05161
Hepatitis B
shr05164
Influenza A
shr05167
Kaposi sarcoma-associated herpesvirus infection
shr05168
Herpes simplex virus 1 infection
shr05200
Pathways in cancer
shr05207
Chemical carcinogenesis - receptor activation
shr05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
shr05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
shr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100927237 (JAK2)
04151 PI3K-Akt signaling pathway
100927237 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100927237 (JAK2)
09143 Cell growth and death
04217 Necroptosis
100927237 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100927237 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
100927237 (JAK2)
04659 Th17 cell differentiation
100927237 (JAK2)
04062 Chemokine signaling pathway
100927237 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
100927237 (JAK2)
04917 Prolactin signaling pathway
100927237 (JAK2)
04935 Growth hormone synthesis, secretion and action
100927237 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
100927237 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100927237 (JAK2)
05207 Chemical carcinogenesis - receptor activation
100927237 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100927237 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
100927237 (JAK2)
05164 Influenza A
100927237 (JAK2)
05168 Herpes simplex virus 1 infection
100927237 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
100927237 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
100927237 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
100927237 (JAK2)
05140 Leishmaniasis
100927237 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100927237 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
100927237 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100927237 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
shr01001
]
100927237 (JAK2)
Enzymes [BR:
shr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100927237 (JAK2)
Protein kinases [BR:
shr01001
]
Non-receptor tyrosine kinases
JAK family [OT]
100927237 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
Jak1_Phl
ABC1
FERM_C_FAK1
RIO1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
100927237
NCBI-ProteinID:
XP_003762178
Ensembl:
ENSSHAG00000014900
LinkDB
All DBs
Position
1:complement(117352050..117496591)
Genome browser
AA seq
1130 aa
AA seq
DB search
MACLTMTEMEESATSSTHQNGDIPGNDDTLKQIEPILQVYLYHSLGKTEGDYLQFPVGEY
IAEEICIAACKACGITPVYHNMFALMSETERIWYPPNHVFHVDEATRYNVLYRIRFYFPH
WYCNGGNRTYRYGISRGAEAPLLDDFVMSYLFAQWRDDFVHGWIKVPVTHETQEECLGMA
VLDIMRIAKEKDQTPLAVYNSTSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIQQFSQ
CKATARILKLKYLINLETLQSAFYSEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSRGK
HKDSETLTEQDLQMYCDFPDIIDVSIKQANQEGSNENRVVTIHKQDSKNLEIEFCSLREA
LSFVSLIDGYYRLTADAHHYLCKEVAPPTVLENIQSNCHGPISMDFAISKLKKAGNQTGL
YVLRCSPKDFNTYFLTFAVERENITDYKHCLITKNENGEFNLSGTKKNFTNLKDLLNCYQ
METVRSDNIIFQFTKCCPPKPKDKSNLLVFRSNGISDVPTSPTLQRHNNVNQMVFHKIRN
EDLIFNESLGQGTFTKIFKGVRREIGDYGQLHETEVLLKVLDKAHRNYSESFFEAASMMS
QLSYKHLVLNYGVCVCGEENILVQEFVKFGSLDTYLKKNKNSINILWKLEVAKQLAWAMH
FLEEKSLTHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVPPE
CIDSPKNLSLAADKWSFGTTLWEICSGGDKPLNALDSQRKLQFYEDRHQLPAPKWTELAN
LINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNTRFGALGFSGAFEDRDPT
QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEIL
KSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERLDHKKLLQYTSQICK
GMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYA
PESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELL
KNNGRLPRPDGCPDEIYSIMTECWNNNVSLRPAFRDLALRVDQIRDDMGG
NT seq
3393 nt
NT seq
+upstream
nt +downstream
nt
atggcttgcctcaccatgacagaaatggaggaatctgccacatcttctacccaccaaaat
ggagatattcctgggaacgatgatactttgaagcagattgagccaattcttcaggtctat
ctttaccactctcttgggaagactgaaggagattatttacagtttccagttggagaatat
attgctgaggaaatttgtattgctgcttgtaaagcttgtggtatcacccctgtctatcat
aatatgtttgctttaatgagtgaaactgagaggatctggtatcctcccaaccatgtcttc
catgtggatgaggcaaccagatacaatgtactctaccgaataaggttttactttcctcat
tggtattgtaatggaggaaatagaacatatcggtatggaatatctcgaggtgcagaggcc
cctcttcttgatgactttgtcatgtcttacctttttgctcagtggcgggatgattttgtt
catggatggatcaaagtacctgtgactcatgaaacacaagaagaatgtcttgggatggct
gtcttagatataatgagaatagctaaagaaaaggatcagaccccactggcagtctataac
tctaccagctacaagaccttcttaccaaaatgtgttcgagcaaagatccaagattatcat
attttgacacgaaagcgaataaggtacagattccgcagatttattcagcagttcagccaa
tgcaaagctactgccagaatcttgaaacttaaatatcttataaatctggaaactcttcag
tctgccttctactcagagcaatttgaagtaaaagaacctggcagaggtccttcaggtgag
gagatttttgcaaccattataataactggaaacggtggaattcaatggtcacgagggaaa
cataaagacagtgagaccctgacagaacaggatttacagatgtactgtgactttcctgat
attattgatgtcagcattaagcaagcaaatcaagaaggttcaaatgagaacagagtggtg
actatccataagcaggatagcaaaaatttggaaattgaattttgctcattgagagaagcg
ctatcttttgtatcattaattgatggatactatagattaactgctgatgcacatcattac
ctttgtaaagaagtagctcctccaacagtccttgaaaatattcaaagcaactgtcatggc
ccaatttcgatggattttgccataagtaaactgaagaaagcaggtaaccagactggactc
tatgtccttcgatgtagccccaaggactttaatacatattttctcacttttgccgttgag
cgggaaaatatcactgattataagcactgtttgattacaaaaaatgagaatggagagttc
aacctcagtgggactaaaaagaacttcactaatcttaaggacctcttgaattgctatcag
atggaaactgtccgctcagataacatcattttccagtttaccaagtgttgccccccaaag
cccaaagataaatcaaatcttctagtcttcaggagtaatggcatttctgatgttcccaca
tcaccaacattgcagaggcataataatgtgaaccaaatggtgtttcataaaatcagaaat
gaagatttaatatttaatgaaagccttgggcaaggcacttttaccaagatttttaaaggt
gtaagaagagaaataggagactatggccagctccatgaaacagaagtcctattaaaagtt
ctggataaagcacatagaaattattcagagtctttttttgaagcagcaagcatgatgagc
cagctttcttacaagcatctggtattaaattatggagtctgtgtttgtggagaagagaat
attctagttcaagaatttgtgaaatttggatcattggacacataccttaaaaagaacaaa
aattctataaacatattatggaagcttgaagtggctaaacagttggcatgggctatgcat
tttcttgaagaaaaaagcctcactcatggtaatgtgtgtactaagaacattttgctaatc
agagaagaggacagaaagacaggaaatcctcctttcatcaagctcagtgatcctggcatt
agtattacagttttgccaaaagacattcttcaagagaggataccatgggtcccacctgaa
tgtattgacagtcctaaaaatctaagtttggcagcagacaagtggagttttggtaccact
ttgtgggaaatctgcagtggaggagacaaacctcttaatgcattagattctcaaagaaaa
cttcagttctatgaagatagacaccagctccctgcaccaaagtggacagaattagcaaat
cttataaataattgtatggactatgagccagacttcagaccttctttccgggccatcata
cgagaccttaacagcttattcactccagactatgaactactaacagaaaatgacatgttg
ccaaatacgagatttggtgccctaggattttctggtgcttttgaagacagagatcccaca
cagtttgaagaaagacatcttaaattcctacagcaacttggcaagggtaattttgggagt
gtggagatgtgccgatatgaccctctacaagacaacactggtgaagtggtggctgtgaaa
aagttacagcacagtactgaggagcacctgagagactttgaaagagaaattgaaattctt
aagtctttacaacatgacaacattgtcaaatacaagggagtgtgctacagtgctggccgt
cgtaacttgaggttaattatggaatatttaccttatggaagtttacgtgactatctccag
aaacataaggaaagactggatcataagaaacttttacagtacacatctcaaatctgcaag
ggaatggagtatcttggtacaaaaagatatatccatagggatctggccacaagaaatatt
ttagtggaaaatgagaatagagttaaaattggagattttggattaacaaaagtcctgcca
caagacaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctggtatgct
ccagaatcactcacagaaagcaagttttctgtagcctcagatgtgtggagttttggagtg
gttctgtatgaacttttcacatatattgagaaaagcaaaagcccaccagcggaatttatg
cgtatgattggtaatgacaaacaagggcagatgattgtattccatctaatagaactttta
aagaataatggaaggttgccaagaccagatggatgtcctgatgagatttattctatcatg
actgagtgttggaacaataatgtaagcttacgccctgccttcagggatcttgctcttcga
gtggatcaaataagagatgacatgggtggatga
DBGET
integrated database retrieval system
