Streptomyces hygroscopicus subsp. jinggangensis 5008: SHJG_6672
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Entry
SHJG_6672 CDS
T02063
Name
(GenBank) D-alanyl-alanine synthetase A
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
shy
Streptomyces hygroscopicus subsp. jinggangensis 5008
Pathway
shy00470
D-Amino acid metabolism
shy00550
Peptidoglycan biosynthesis
shy01100
Metabolic pathways
shy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
shy00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SHJG_6672
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SHJG_6672
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SHJG_6672
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
shy01011
]
SHJG_6672
Enzymes [BR:
shy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SHJG_6672
Peptidoglycan biosynthesis and degradation proteins [BR:
shy01011
]
Precursor biosynthesis
Amino acid ligase
SHJG_6672
BRITE hierarchy
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AEY91939
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Position
7587583..7588740
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AA seq
385 aa
AA seq
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MSTENLPQSPEQPQRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTKYDVLPIGITADG
RWALTADEPERMVITDRRTPSVAELAESDEGGVVLPVDPANREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRIFTSYGLKVGPYLV
IRPREWARDESAARKKIIDFAGEHGWPLFVKPARAGSSIGITKVEDLSGLDEAIAEAQAH
DPKILVEAAVRGREIECGVLEFEDGPRASVPAEIPPPDAHAYYDFEAKYIDSTPGVVPAP
LTEEQTAEVRWLAVEAFEATSCEGLVRADFFLTEDGEFVINEVNTMPGFTPISMYPQMWQ
ASGISYPELVDRLVQAALRRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaaccttccccagagccctgagcagccgcagcgcaagccgcgcgtggcc
gtcgtgttcggcgggcgcagttccgaacacgggatctccgtggtcaccgccggcgccgtc
ctcaaggccatcgaccggacgaagtacgacgtcctgccgatcggcatcaccgcggacggc
cgctgggcgctgacggccgacgagccggagcggatggtcatcaccgaccgccgcaccccc
agcgtggcggagcttgcggagtcggacgagggcggcgtggtgctccccgtcgacccggcg
aaccgcgaggtcgtctacagcgagcccggctccgtgcccaaggcgctcggcgaggtcgac
gtggtcttcccggtgctccacggcccctacggcgaggacggcaccctccagggcctgctg
gagctgtccggagtgccctacgtgggctccggcgtgctcgcctcggccgtcggccaggac
aaggagtacatgaagcggatcttcacctcctacgggctcaaggtcggcccgtacctggtg
atccggccccgcgagtgggcccgggacgagtccgccgcccgcaagaagatcatcgacttc
gccggcgagcacggctggccgctgttcgtgaagcccgcgcgcgcgggctcgtccatcggc
atcacgaaggtcgaggacctgtccggcctggacgaggcgatcgccgaggcgcaggcccac
gacccgaagatcctggtcgaggcggccgtacgcggccgtgagatcgagtgcggcgtcctg
gagttcgaggacggcccgcgcgcctccgtcccggccgagatcccgccgccggacgcgcac
gcgtactacgacttcgaggccaagtacatcgactccacgcccggcgtcgtcccggccccg
ctcaccgaggagcagaccgccgaggtgcgctggctcgccgtcgaggcgttcgaggcgacc
tcctgcgagggcctggtccgcgcggacttcttcctcaccgaggacggcgagttcgtgatc
aacgaggtcaacacgatgcccggcttcacgccgatctcgatgtacccgcagatgtggcag
gcgagcgggatcagctaccccgagctggtggaccgcctggtgcaggcggcgctgcgccgc
ccgacggggctgcgctga
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