Streptomyces kanamyceticus: CP970_03420 Help Entry CP970_03420       CDS       T06849                                  Name (GenBank) type I polyketide synthase Organism ska  Streptomyces kanamyceticus SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C PP-binding KAsynt_C_assoc adh_short PKS_DE Epimerase Thiolase_N PKS_DH_N adh_short_C2 PS-DH GDP_Man_Dehyd Polysacc_synt_2 ACP_syn_III Docking NmrA RmlD_sub_bind Motif Other DBs NCBI-ProteinID:  QEU90083 UniProt:  A0A5J6G550 LinkDB All DBs Position complement(926192..945388) Genome browser AA seq 6398 aa AA seqDB search MENENKLRDYLKRATTDLRNARRRLREVEEREHEPIAIIGMSCRYPGGVTSPEDLWRLVA DGGDAVVEFPADRGWDTEALHDPDPEHAGTSITRHGGFLQGATEFDPAFFGVNPREAAAM DPQQRLLLETSWEAFERAGIDPAQARESRTGVFAGVMYNDYATRLPQAPEGFEGYLANGS AGSIASGRIAYTLGLVGPAVTVDTACSSSLVALHLAMVALRRDECTLALAGGATFMSTPR TFVEYSRQRALSVDGRCKAFSDGADGTGWGEGVGMLLVERLSDARRNGHPVLAIVRGSAV NQDGASHGLTAPNGPSQQAVITQALASASLTAADVDAVEAHGTGTTLGDPIEAQALIATY GQDRPADRPLWLGSLKSNIGHSQAAAGVGGIIKMVMAMRHGTLPKTLHVDEPSSHVDWSA GAVELLTEGRAWPETGEPRRVGVSSFGVSGTNAHVILEQGPAADQEPAETTGEPVAGATP WALSAMTPAGLRAQADRLLSALRDTDGTDERDGSHDFDAAAVGFSLATTRAVFEHRAVLL ADNDDKAATLDRLAALAEGRGAPGVVVGEAATHRLGFLFSGQGSQRLGMGRELASRFPVF ADALEEVLSLLAPEVREVLFGEDVDALNETGVTQPALFAVEVALFRLLESWGVRPDVLAG HSIGELAAAHVSGVWSLADAVKVVSARGALMQALPAGGAMVALQASEAEVVPDLPDNVGI AAVNGPESVVISGPTADVEAVAEQWRDAGRKVSRLRVSHAFHSPLMDPMLDDFRAVLESV SYEAPAIPIVSTLIGSLASADDLTSPEYWVRHVREGVRFHDAVTALREHGVDVFLEIGPG GVLSGLGQLSASDAAFVPALRGDRTELDALTTAVGQLHVRGVAVNLAACFADGDARRVDL PTYAFQRERYWLDAPADDAATEPMSPVEARFWETVEEGDLGDLARTLGVSSDDPLSAVLP RLSAWRRKQRERSTADGWRYAVEWRPLAAGNQRLDGTWLVVAPVGEERAAWVRDALTRNG AETRLVEVDPESADWPEQLNELPALGGVVSLLGLTATEGPGIPAGLSSTIGLLRALDDAE VQAPLWCLTSGAVSVGADDALTALDQSMVWGLGRVAALERPGSWGGLVDVPQTRDEAAGD LLASVLSGARDEDQIAVRGGEILGRRLVPAPLGDTPVEGWTPRGTVLVTGGLGALGGHVA RWLAVRGAEHVVLASRRGQAAEGAAELAAELVRLGARVTFAACDVADRESVAALIESLPE LTAVVHTAGIERAVALADLDPSDLGEFADVLAAKADGARNLHELLADRTLDAFVLFSSIA GVWGSGGQPAYGAANAYLDALAEHRRAAGLPATAVAWGPWGGGGMVADSGQAAHLRRRGL NTMTPEAALAGLGAAVDHGDATVTLADVDWDRFAGTFMAQRPSPLLSELPQVQAAFEASA PEQGTSALAQRLAGLDEAEQERQLTDLVRYEAAAVLGHVSGEAFSATRAFRELGFDSLTA VELRARLSEVTGIALPSTLVFDYPTAAELATHLRTELSGANADSTSATPVAASGVTDEPI AIVGMACRFPGGVASPEDLWQVLRSGGDAVSEFPTDRGWDLETLYDPDATRAGTSYTRKG AFLDQVAEFDPAFFGISPREALAMDPQQRLLLETSWEAVERAGIDAHALRGSRSGVFVGT NGQDYTTLMMAAPDTVEGYFGTGSAASVISGRLSYTFGLEGPAVTVDTACSSSLVALHLA VQALRSGECEMALAGGVTVMSTPAAFVEFSKQRGLSFDGRCKAFGADADGTGWGEGIGML VVERLSDAERNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAAAGLAPSEVD AVEAHGTGTKLGDPIEAQALLATYGQDRPADQPLLLGSIKSNIGHTQAAAGVAGVIKMVM AMRHGVLPKTLHADEPSPHVDWSAGALELLADEREWPAADRPWRAGVSSFGFSGTNAHVI VEQAPVVEREQAPEPLPVGTVVPWALSATTPEGLREQAARLKSFVDEAPSDLSVADVSRA LLFSRAALEHRAVLVATEPAEFLSALTAVAEGRGGPGVVTGEASGARRVGFLFSGQGSQR LGMGRELASRFPVFADALDEVLELLAPEVREVLFGEDVDALNETGVTQPALFAVEVALFR LLESWGVRPEALAGHSIGELAAAHVSGVWSLADAVKVVSARASLMQALPEGGAMVAIQAA EAEVASDLPDGVGIAAVNGPSSVVISGVAADVEAVAERWRETGRKVSKLRVSHAFHSPLM DPMLDDFRQVVEGVACGEPEIPIVSTLTGRSATAEELASPEYWVRHVRESVRFADAVNTL VADGIDTFVEVGPGGALSALGQESAPDAAFVPVLRGDRPEPVAATTAAGQLHVRGVAVDW EEFLAGRGSQWVDLPTYAFQRERFWLDVSPVGEGVGRMSPVEARFWEAVEEGDVADFART LDVSSDDPLSAVLPRLSAWRKEQQDRSVADGWRYGVMWRPVAAGSRQLDGTWLVVAPAGE DRAAWVRDALTRNGAEAQVVEVDPESADWSRQLSELPALSGVVSLLALADAGVAHTVALL RSLGDAGVSAPLWCLTSGAVAAGADDAVSGFEQSMVWGLGRVAALEQPGGWGGLVDVPNF GDDDATGDLLASVLAGTSGEDQVAVRGGELLGRRLVPAPLSAEAPGSGWTPRGTVLVTGG LGALGGHVARWLATHGAEHVVLASRRGADADGSDELAAELAELGARVTFAACDVADRESV AALLESVPELTAVVHTAGIERSAVLADLGADELADVLAAKVDGARNLHELLADVPLDAFV VFSSIAGVWGSSGQGAYAAANAYLDALAQHRRARGLPATAVAWGPWGGGGMVATTEQAAL LHRWGLSTMAPAVAIVGLATALERGEGNVVVADVDWERFAGTFMAQRTSPLLSELPQVQA AFEASAPEQGSSALAQRLAGLDQAEQERQLTDLVRYEAATVLGHVSADAFSATRAFKDLG FDSLTAVELRTRLSDATGVALPATLVFDYPTAAELAAYLRTQLSGVSADSTTTAPVAASG AAADEPIAIVAMSCRFPGGVSSPDDLWQVLLSGGDGVTDFPADRGWDVEALYDPDPDSVG TTYLRSGAFLSDVSGFDAGFFGISPREALAMDPQQRLLLETSWELLERAGIDPASLRGER VGVFVGSNAQDYGLVLGESGEDVGGYMATGNAASVASGRLSYTFGFEGPAVTVDTACSSS LVALHLAVQALRSGECEMALAGGVTVMSTPGAFIEFSRQRGLSLDGRCKAFAAAADGTSW GEGVGMLFVERLSDAERNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALATAG LSPSDVDAVEAHGTGTKLGDPIEAQALLATYGQDRPEDRPLWLGSVKSNIGHTQAAAGVA GVIKMVMAMRHGVLPRTLHVDAPSPHVDWSAGAVELLTQDRPWPETGQPWRAGVSSFGFS GTNAHAIIEQAPVVEPVEVSEPTTYDGGVLPWVLSAGDEGALRGQAERLLSVVDEHAPVE VGYSLATSRAALDRRAVVVAAEPAEFLSALSALAEGREAPGVVLGEASGSQRVGFLFSGQ GSQRLGMGRELADRFPVFATALDEVLDVLAPEVRGVLFGEDVDALNQTGVTQPALFAIEV ALFRLLESWGVRPDVLAGHSIGELAAAHVAGVWSLADAAKVVSARAGLMQALPEGGAMVA IQATEEELAGYLSETVGIAAVNGPSSVVISGVAADVEAVAERWREAGRKVSKLRVSHAFH SPLMDPMLDDFRTVLASVSYEAPSIPIVSTLTGARATSEELSSPEYWVRHVRESVRFADA VSALVAEGVTAFVEVGPGGTLAALGLASAPDAVFLPALRADRAEDVALVTTVAALHARGV AVDWSAYFAGSGARRVDLPTYAFQHQRYWSDARPGKSDALADADEAEFWAAVDSEEAGAL ASSLGITDDGETDSLRAVLPLLSSWRRQSREKSAMDKWRYTVEWTAVADPATTPPSGTWL AVAPAGDERAAALGELLKERGLSVVAVEAEGADREALADALRAAATDALRAAAPGAEISG VLSLLAFDESPHPEHPAVPNGVAATIALFQALGDTDVRAPLWCLTSGAVSATAEDAVGGF AQSMVWGLGRAAALEHPDRWGGLVDLPETVDEAAAARLCGLIGGAEDQVAVRGTGVFTRC LRRAGRATASSGWTPRGTVLVTGGLGALGARAARWLAEHGAEHVVLVSRRGPEAAGAAEL DAELAELGARVTVAAVDIADRERLAALLDDLAAAGDPVRAVVHTAGLNDSVPADTTDLAR FADVVTAKVAGAAHLHELLADAPLDAFLSYSSIAGIWGSGGQLAYSAANAYLDALTEHRA ARGLPATTVAWGPWAGGGMADDEAQRQLSRRGLLALAPELAVGALADAVGGGTPSTVVVN VDWARFAPAFTIGRPSPLLADLAEARDAIADRADGAGRADASDTGDEKGAALRSRLTGLD AAKQKELVRGLVAAEAAAVLGHASAAAVDPDRAFRELGFDSLTAVELRNRLTAASGLTLP ATVVFDYPSPAVLAEHLLTEVVAPHGESLVAPAAAAPGVTDEPIAIVAMACRYPGGVANP EDLWRVLREGGDAVAEFPADRGWDMETLYDPDPEGVGTTYSRRGAFLDRVADFDASFFGI SPREALAMDPQQRLLLETSWETFERAGMDPNAIRGERVGVFVGSNVQDYGMVLDGAAEDV GGHVATGSAASVMSGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALHQGECEMALAGG VTVMSTPGAFIEFSRQRGLSVDGRCKAFADAADGTGWGEGIGMLLVERLSDAERNGHQVL AVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLAASDVDAVEAHGTGTKLGDPIE AQALLATYGQGRDADRPLWLGSIKSNLGHTQAAAGVAGIIKMVMAMRHGVLPRTLHVDEP STHVDWSAGAVRLLTDERDWPAVDRPWRAGVSSFGFSGTNAHTVIEQAPQTASAEAEADA DAGPAETGVVPWVLSARSVEALREQAARLRDECAHETAAPVADIAHSLRTRSTFDRRAVV VGRDREDFLSGLTALAEGREAPNVVTGVAEHHGTGPVFVFPGHGTQWLGMAGDLLESSPV FRTRMQECAAALAEHVDWSLLDAIHDDALMERLDVVQPALFAVMVSLAATWRSWGVEPSA VLGHSQGEIAAACVAGALTLQDAARLVVVRSKALSALSGRGGMVSVALDVDGVRELIAIW AGQLAIGVVNGPASVVVSGDVGALDELVETCAEQGIWARRVLADYAPHSHHVERIEADIL AGLADVTPRSGDVPYYSPLTGGWLDTRELDAAYWYRSLRQTVEFADSVTDLVAAGHTAFV EVSPHPVLVAGLGELVGADGVVVGSLRRGDGGLTRLTTSASGLFVRGGQVAWPTPGGRRV DLPTYPFQRKRFWPTTTHTATGDVTSAGLGRVDHPVLAAVTELPDSESLVFSGRLSLRTH PWLTDYRVLGSAVLPGAAYVELALCAGDHVGCASLDDLVLEAPLVLPERDGVQVRLSLHG PDDSGRRAFTVDSRGDEGGDWTRHATGALTDRAEPVTDTLVAWPPSEAEPVDLDTHYSAV AASGLDHGPAFQGLNAAWRKGDEVFAEVALPEGLADDGFGLHPALLDTALHAVSLGVSSD GLPFSWAGVRLLATGATVLRVRLTPVGVDAVAVLVADGTGEPVAAVDELNLRPLSADQLN LARSAHRDSLFEVKWVPTQDAAPDTGTWAVLGAGTGTDRLVQALTAAGEQVDEHADLAAL SAAVDSGAPAPRYVTVTPGGDAATPREATHHALGLLQDWLADDRFADSRLVVLTSGAVAA GPDEDVPDLVRAPVWGLVRSAQSEHPTRFALVDLVDTDDDARSARKLPAAVATGEPQLAI RDGVASVPRLARLAAHADAPDTVAFTPDSVVLITGGLGVLGGVTARHLVTRHGVRDLVLT GRRGTATPGADELRAELEALGARVTVAACDVSDRDAVAALLAEHPVTALVHTAGVLDDGV IGSLTPEQVDAVLRPKADAARHLHELTRDSGFTAFVLFSAAAGVFGGPGQGNYAAANAYL DALAQHRRAVGLPATSLAWGLWAEATGITGHLDDADVQRMARGGMVPLSTADGMALFDEA RATGAASAVPAALDLAALRAHPERVRPLLRGLVPTPARRSARSGDGAGTVPLAQRLAGLT EAEQDRALVHLVRTHTAAVLGFAGPDAVEADRAFKELGFDSLTAVELRNRLDAEVDTRLP ATLVFDHPTPGALAAHLRTTVVTDQASPAAAVLSELNKLTITMSKLDPDDALAGDIRLRL RSLLSTWEEQEQEAAVDDLSSATLDDVFDIIDEELGKS NT seq 19197 nt NT seq  +upstreamnt  +downstreamnt atggagaacgagaacaagctccgcgactacctcaagcgggcgaccaccgacctgcgcaac gcccgccgccgcctgcgcgaggtcgaggagcgcgagcacgagcccatcgcgatcatcggg atgagctgccgctaccccggtggcgtcacctcgccggaagacctctggcgcctggtcgcc gacggcggcgacgccgtggtggagttccccgccgaccgcggctgggacaccgaagccctg cacgaccccgacccggagcacgcgggcacctccatcacccggcacggcggattcctccag ggcgcgacggagttcgacccggcgttcttcggcgtcaacccgcgcgaggccgcggccatg gacccgcagcagcgcctgctcctggagacctcctgggaggcgttcgaacgcgcgggcatc gacccggcccaggccagggagtccaggaccggcgtgttcgcgggcgtcatgtacaacgac tacgcgacgcgcctgccgcaggctcccgaagggttcgagggctacctcgccaacggcagc gcgggcagcatcgcctccggccgcatcgcctacaccctcggcctcgtcggacccgccgtg acggtggacaccgcctgctcctcgtccctggtggccctgcacctggcgatggtggcgctc cgccgcgacgagtgcaccctcgcgctcgcgggcggcgccacgttcatgtccacgccccgc acgttcgtcgagtacagcaggcagcgcgcgctgtccgtggacggccgctgcaaggcgttc tccgacggcgccgacggcaccggctggggcgagggcgtcggcatgctcctggtggagcgg ctctccgacgcccgccgcaacggccacccggtcctcgcgatcgtgcgcggctccgccgtg aaccaggacggcgcgtcccacggcctgaccgcgcccaacggcccctcccaacaggccgtg atcacccaggcgttggcgagcgcgagcctcaccgcggccgacgtggacgccgtcgaggca cacggcacgggcaccaccctcggcgaccccatcgaggcgcaggccctcatcgccacgtac ggccaggaccggcccgcggaccggcccctgtggctgggttcgctgaagtcgaacatcggc cactcccaggccgcggcgggcgtcggcggcatcatcaagatggtcatggcgatgcggcac ggcacgctgcccaagaccctccacgtcgacgagccgagcagccacgtcgactggtcggcg ggcgcggtggaactgctgaccgaaggccgggcatggcccgagaccggtgaaccgcgccgc gtcggcgtctcctcgttcggcgtcagcggcacgaacgcccacgtcatcctggaacagggc cccgccgccgaccaggaacccgccgagaccactggcgagcccgtcgccggagccaccccg tgggcgctgtccgccatgacgcccgccgggctgcgcgcccaggccgaccgcctcctgtcc gccctgcgggacaccgacggcacggacgagcgcgacggctcccatgacttcgacgcggcc gccgtcggcttctccctggccaccacacgcgccgtgttcgagcaccgcgccgtgctcctc gccgacaacgacgacaaggccgccaccctcgaccggctcgccgcgctcgccgagggccgc ggcgctcctggcgtcgtcgtgggcgaggccgccacccaccggctcggcttcctgttctcc ggtcagggttcgcagcggctcggcatgggccgtgaactggcctcccgtttcccggtgttc gcggatgcgctggaagaggtcctgagcctgctggcccccgaggtgcgcgaggttctcttc ggtgaggacgtcgacgcgctgaacgagacgggtgtgacgcagcccgcgttgttcgcggtc gaggtggcgctgttccggcttcttgagtcgtggggtgtacgtcctgacgtgcttgctggt cactcgatcggtgagctggctgcggcacatgtgtcgggtgtgtggtccctcgcggacgcg gtcaaggtggtgtccgcgcgtggcgcgctgatgcaggcgctgcccgcgggcggcgcgatg gtcgccctccaggcgagtgaggccgaggtcgtccccgacctgccggacaacgtgggcatc gccgcggtgaacggccccgaatccgtggtgatctcgggccccaccgccgacgtggaggcc gtcgcggagcagtggcgcgacgcgggccgcaaggtgagccgactgcgggtgagccacgcc ttccactcgccgctgatggacccgatgctcgacgacttccgcgcggtcctggagagcgtg tcctacgaagctcccgcgataccgatcgtgtcgacgctgataggcagcctggcgagcgcc gacgacctgacgtcgcccgagtactgggtacgccatgtacgcgagggcgtgcggttccac gacgcggtcaccgcactgcgcgagcacggcgtcgacgtcttcctggagatcggccccggt ggcgtcctgtccggcctcggccagctcagtgcctccgacgcggccttcgtccccgccctg cgcggcgacaggaccgaactcgacgcgctgaccacggccgtcggacagctgcacgtgcgc ggcgtcgcggtgaacctggccgcctgcttcgccgacggcgacgcccgacgcgtggacctg cccacgtacgccttccagcgcgagcgctactggctggacgcccccgccgacgacgcggcc accgagccgatgtcgccggtggaggcccggttctgggagaccgtggaagagggcgacctc ggcgacctcgcccgcacgctgggcgtgtcgtcggacgacccgctgagcgccgtactgccc cgcctctccgcctggcgcaggaagcagcgggaacgttccaccgcggacggctggcggtac gccgtcgaatggcggccgttggccgcggggaaccagcgcctcgacggcacgtggctggtc gtggcgccggtcggcgaagagcgggccgcatgggtgcgggacgcgctgacacgcaacggc gccgagacgcggctcgtggaggtggacccggagtcggccgactggccggagcagttgaac gagctgcccgcactgggcggtgtggtctcgctcctggggctcaccgccaccgaaggaccc ggcatccccgcgggcctcagctccacgatcggcctcctgcgggcgctcgacgacgcggaa gtccaggctccgctgtggtgcctcacatccggtgcggtgtcggtgggcgcggacgacgcc ctgaccgcgctcgaccaatcgatggtgtggggcctcggccgggtggccgccctggagcgg cccggcagctggggcggtctcgtcgacgtcccgcagacgcgcgacgaggcggccggtgac ctgctggcgtcggtcctctccggtgcgcgcgacgaggaccagatcgccgtacgcggcggt gagatcctcggccgcaggctggtgcccgcgcccctgggcgacaccccggtggagggctgg acgccgcgcggcacagtgctcgtcaccggtggcctcggcgccctcggcgggcacgtggcg cgctggctcgcggtgcgcggggccgagcacgtggtgctggccagccgccgcggccaggcg gccgaaggcgccgctgagctggcggccgaactcgtccggctgggcgcccgggtgacgttc gcggcctgtgacgtggcggaccgggagtccgtcgcggcgctcatcgaaagcctccccgag ctgaccgcggtcgtgcacacggcgggcatcgagcgcgccgtcgccctcgccgacctcgac ccgtccgacctgggcgaattcgccgacgtgctggcggccaaggccgacggcgcgcgcaat ctgcacgagctgctcgccgacaggacgctggacgcgttcgtcctgttctcgtcgatcgcc ggtgtgtggggcagtggcggccagcccgcctacggcgcggcgaacgcctacctggacgcg ctggccgagcaccgcagggccgcgggtctgcccgccaccgcggtggcgtggggcccgtgg ggcggcggcggcatggtcgccgactccgggcaggccgcgcacctccggcgcaggggcctg aacacgatgacccccgaagcggcgctcgccggtctcggcgcggccgtcgaccacggcgac gcgacggtgaccctcgccgacgtcgactgggaccgtttcgccggtacgttcatggcgcag cgcccgagcccgctcctgagcgaactcccgcaggtccaggccgcgttcgaggcatcggcg cccgagcagggcacatcggcccttgcgcagcggctcgccggtcttgacgaggccgagcag gagcggcagctcaccgacctcgtccggtacgaggcggcggcagtcctcggccacgtgtcc ggcgaggcattctccgcgacccgtgccttccgtgagctgggcttcgactcgctgacggcg gtggaactgcgggccaggctgagcgaggtcacgggcatcgccctgccctcgacactggtc ttcgactacccgaccgccgccgaactggccacccatctgcggaccgaactgtccggcgcg aacgcggactccacctcggcgacccccgtggccgcctcgggcgtgacggacgaaccgatc gcgatcgtgggcatggcatgccggttccccggtggcgtggcaagccccgaggacctgtgg caggttctgcggtcgggcggcgacgcggtgtcggagttcccgaccgaccgcggctgggac ctggagacgctgtacgacccggacgccacgcgcgccggaacctcgtacacgcgcaagggt gccttcctcgaccaagtggcggagttcgacccggcgttcttcggcatctcgccgcgcgag gccctggcgatggacccgcagcagcgcctgctcctggagacctcctgggaggccgtcgag cgcgcgggcatcgacgcgcacgccctgcgaggcagccgttccggcgtgttcgtcggcacc aacggccaggactacacgaccctgatgatggccgctccggacaccgtcgagggctacttc ggcacgggcagcgcggcgagcgtcatctcgggccggttgtcctacacgttcggcctggag ggcccggccgtcacggtcgacacggcatgctcgtcgtccctggtcgccctgcacctggcg gtgcaggcgctgcggtccggtgagtgcgagatggcgctcgcgggcggcgtgacggtgatg tccacccccgccgcgttcgtggagttcagcaagcagcggggcctgtccttcgacggccgc tgcaaggcgttcggcgcggacgcggacggcacgggctggggcgagggcatcggcatgctc gtcgtcgagcgcctgtcggacgccgagcgcaacggccaccaagtgctcgctgtcgtacgg ggttcggcggtgaaccaggacggcgcgtccaacggtctcacggcccccaacggcccctcg cagcagcgcgtgatccgccaggcgctcgcggccgccggtctcgctccgtccgaggtggac gcggtcgaggcgcacggcaccggcacgaagctgggcgacccgatcgaggcgcaggcgctc ctcgcgacgtacggccaggaccggcccgccgatcagccgctcctgctcggctcgatcaag tccaacatcggtcacacccaggcggcggccggtgtggcgggtgtcatcaagatggtcatg gcgatgcgccacggcgtcctgcccaagaccctccacgcggacgagccttcgccgcacgtc gactggtccgccggtgcgctggaactcctcgccgacgagcgcgagtggcccgccgcggac cgcccgtggcgggcaggtgtgtcctcattcggcttcagcggcaccaacgcacatgtgatc gtggagcaggcccctgtcgtcgagcgggagcaggccccggagccgctgcccgtcggcacg gtcgtcccgtgggcactgtcggccaccacccccgaggggctgcgcgagcaggccgcacgg ctgaagtccttcgtggacgaggcgccgtcggacctgtccgtggcggacgtgagccgtgcg ctgctgttctcgcgtgcggcccttgagcaccgcgcggtgctcgtcgccacggagcccgcc gagttcctgtcggccctgaccgccgtcgccgaggggcgcggcggcccgggtgtggtgacg ggcgaggcgtccggtgcgcggcgggtgggtttcctgttctcgggtcagggttcgcagcgg ctgggcatggggcgtgaactggcgtctcgtttcccggtgttcgcggatgccctggacgag gtgcttgagctgctggctcctgaggtgcgcgaggtcctcttcggtgaggacgtcgacgcg ctgaacgagacgggtgtgacgcagcccgcgctgttcgcggtcgaggtggcgctgttccgg cttcttgagtcgtggggcgtacgtcctgaggcgctggccggtcactcgatcggtgagctc gcggcggcacatgtgtcgggtgtgtggtccctggcggatgccgtcaaggtcgtgtcggcg cgtgcgagtctgatgcaggcgctgcccgagggcggcgcgatggtcgcgatccaggcggcg gaggccgaggtcgcctcggacctgccggacggtgtgggcatcgcggcggtcaacggcccg tcctcggtggtcatttccggtgtcgccgccgacgtggaggccgtcgccgagcgctggcgc gagacgggccgcaaggtcagcaagctgcgtgtcagtcacgcgttccactcgccgctgatg gacccgatgctggacgacttccgccaggtggtcgagggcgtcgcatgcggtgagcccgag atcccgatcgtatcgacgctgaccggccggtcggctacggcagaagagctggcctccccg gagtactgggtgcgccacgtgcgcgaatcggtgcgcttcgccgacgccgtgaacacgctc gtcgccgacggaatcgacacgttcgtcgaggtcggcccgggcggcgcgctgtcggccctc ggccaggagtccgcgccggacgccgccttcgtgcccgtgctgcgcggtgatcgccccgag ccggtggccgccacgacggccgcgggtcagctgcacgtacgcggtgtggcggtggactgg gaggagttcctcgccggacgcggctcacagtgggtggatctgccgacgtacgcgttccag cgtgagcgtttctggctggacgtctcgccggtgggtgagggcgtcggccggatgtccccg gtggaggcgcggttctgggaggccgtcgaggagggtgatgtcgcggacttcgcccggacg ttggacgtgtcgtcggacgacccgctgagtgcggtgctgccccgcctgtccgcgtggcgc aaggagcagcaggaccgctctgtcgcggatggctggcggtacggggtcatgtggcggccg gtggccgccgggtcccggcagctggacggtacgtggctggtcgtggcgccggccggtgag gaccgggccgcgtgggtgcgggacgcgctgacgcgcaacggcgccgaggcgcaggtcgtg gaggtggacccggagtcggccgactggtcgcggcagctgagcgaactgcccgcactgagc ggtgtggtgtcactgctggcgctcgcggacgcgggtgtcgcgcacacggtcgccctcctg cgctccctcggtgacgcgggtgtgtcggctccgctgtggtgcctgacgtcgggtgcggtg gcggcgggtgcggatgatgccgtgtccgggttcgagcagtcgatggtgtggggccttggc cgggtggccgcgttggagcagccgggtggctggggtggtctggtcgacgtcccgaacttc ggcgacgacgatgcgacgggtgacctgctggcctcggtcctcgccgggacgagtggtgag gaccaggtcgccgtacgcggtggtgaactcctcggccgacgtctggtccccgcgccgctg agcgcggaggcccctggttccggctggacgccgcgcggcacggtgctcgtcaccggtggc ctcggcgcccttggcgggcatgtggcgcgctggctggcgacacacggcgccgaacacgtg gtgctggcaagccgtcgcggcgccgatgccgacggctccgatgaactggcagccgagctg gcggagttgggcgcgcgggtgacgttcgcggcctgcgacgtggctgaccgggagtccgtc gcggcgctcctcgaaagcgtccctgagctgaccgcggtcgtgcacacggcgggcatcgag cgctccgctgttctcgccgacctcggcgcggacgagctcgcggacgtgctggccgccaag gtcgacggcgcgcgcaacctgcacgagctgctcgccgacgtgccgttggacgcgttcgtc gtcttctcgtcgatcgcaggcgtgtgggggagcagcggccaaggcgcgtacgcggccgcc aacgcctacctcgacgcgctcgcccagcaccgccgtgcccggggcctgcccgccacggcc gtggcgtggggcccgtggggcggtggcggcatggtcgccaccaccgagcaggccgcgctg ctgcaccgctggggcctgtcgacgatggctccggccgtcgcgatcgtgggcctggcgacg gctcttgagcgtggcgagggcaacgtcgtcgtcgccgatgtcgactgggagcgcttcgcg ggtacgttcatggcgcagcggaccagtccgctcctgagcgaactcccgcaggtccaggcc gcgttcgaggcatcggcgcccgagcagggctcgtcggcccttgcgcagcggctcgcaggg cttgaccaggccgagcaggagcggcagctcaccgacctcgtccggtacgaggcggccacg gtactcggccacgtctcggccgacgccttctccgccacgcgtgccttcaaggacctgggc ttcgactcgctgacggcggtggaactgcggacccgactgagcgacgccacgggcgtcgcc ctgcccgcgaccctggtcttcgactacccgaccgccgccgaactggccgcgtatctgcgc acccaactgtcgggtgtgagcgcggactccacgaccaccgctcccgtggcagcttcgggt gcggcggcggacgagccgatcgcgatcgtggccatgtcctgccggttccccggtggcgtg tcgagccccgacgacctctggcaggtgctgctctccggcggcgacggcgtgaccgacttc ccggccgaccgtggctgggacgtcgaggcgctgtacgaccccgacccggactccgtgggc accacgtacctgcgctcgggcgccttcctgtcggacgtgagcggcttcgacgcgggcttc ttcggcatctcgccgcgcgaggcgctcgccatggacccgcagcagcggctgctcctcgaa acctcctgggaactgctcgagcgcgcgggcatcgaccccgcctcgctgcgcggtgagcgc gtcggcgtgttcgtcggctcgaacgcccaggactacggcctcgtcctcggcgagtccggc gaggacgtcggcggctacatggcgaccggcaacgcggcgagtgtggcctcgggccgcctc tcgtacaccttcggcttcgaaggcccggcggtcacggtcgacacggcgtgctcctcgtcc ctggtcgccctgcacctcgcggtgcaggccctgcgctcgggcgagtgcgagatggcgctc gcgggcggtgtgaccgtgatgtcgacgccgggtgcgttcatcgagttcagccgccagcgc ggtctgtcgctggacggtcgctgcaaggcgttcgcggccgcggccgacggcaccagctgg ggcgagggcgtcggcatgctgttcgtggagcgcctgtcggacgccgagcgcaacgggcat caagtgctggctgtcgtacggggttcggcggtgaaccaggacggcgcttccaacggcctg actgctccgaacggtccctcgcagcagcgcgtgatccgccaggcgctcgcgacggcgggt ctctctccgtccgacgtggacgccgtcgaggcgcacggcacgggtaccaagctgggtgac ccgatcgaggcgcaggcgctcctcgcgacgtatggccaggaccgacccgaggaccggccg ctgtggctgggttcggtgaagtcgaacatcggtcacactcaggccgccgcgggtgtggca ggtgtgatcaagatggtcatggcgatgcgccacggcgtactgccccgcaccctgcacgtc gacgcgccgtcgccgcacgtcgattggtcggcaggcgcggtggagctcctgacgcaggac cgcccgtggccggagaccggccagccgtggcgtgcgggtgtgtcgtcgttcggcttcagc ggcacgaacgcacacgccatcatcgagcaggcccctgtcgtcgagccggtcgaggtctcg gagccgacgacgtacgacggtggtgtgctgccgtgggtgctgtccgcgggtgacgagggt gcgctgcgcgggcaggcggagcgtctgctgtccgtcgtcgacgagcacgcgcccgttgag gtcggctactcgctcgccacgtcacgcgcggcgctggaccgccgagcggtggtcgtcgcc gccgagcccgccgagttcctgtcggccctctccgctctcgccgagggccgggaagcgccg ggcgtcgtgctgggcgaggcatccggttcgcagcgggtgggtttcctgttctcgggtcag ggttcgcagcggctcggcatgggccgtgaactggcggaccgtttcccggtgttcgccacc gctctggacgaggtccttgatgttctggctcctgaggtgcgtggggtcctcttcggtgag gacgtcgacgcgctgaaccagacgggtgtgacacagcccgccctgttcgcgattgaggtg gctctcttccggcttcttgagtcgtggggtgtacgtcctgacgtgcttgctggtcactcg atcggtgagctcgcggcggcccatgtcgcgggtgtgtggtcgcttgcggacgccgccaag gtggtgtcggctcgtgcgggtctgatgcaggcgttgcccgagggtggcgcgatggtcgcg atccaggcgaccgaagaggaactcgccggatatctttcggagaccgtcggtatcgcggcg gtcaacgggccctcatcggtggtcatttcgggtgtcgcggccgacgtggaggccgtcgcc gagcgctggcgtgaggcgggccgcaaggtcagcaagctgcgtgtcagtcacgcgttccac tcgccgctgatggacccgatgctcgatgacttccgtacggtcctggcgagcgtctcgtac gaggctccctcgatcccgatcgtgtccaccctgaccggcgcacgcgccacctccgaggaa ctgtcctcgcccgagtactgggtgcgtcacgtccgcgaatcggtgcgtttcgccgacgcc gtgagcgccctggtcgcagagggcgtgaccgcgttcgtcgaggtcggccccggcggcacg ctggccgccctcgggctcgccagtgcgccggacgcggtgttcctgcccgcgctgcgcgcg gacagggccgaggacgtcgccctcgtcaccacggtcgccgcgctccacgcgcggggcgtg gccgtcgactggagcgcctacttcgccgggagcggggcgcgacgcgtcgacctgccgacg tacgcgttccagcaccagcgctactggtccgacgcgcgaccgggcaagagcgatgccctc gcggacgcggacgaggcggagttctgggccgcggtggacagcgaggaggcgggcgcgctc gcgtcgtccctggggatcaccgacgacggggagaccgactccctccgcgcggtgctgccc ctgctgtcgtcgtggcggcgccagagccgtgagaagtccgccatggacaagtggcgttac accgtcgagtggacggccgtggccgacccggcgaccacgcctccctcgggcacctggctg gccgtggcgcccgcgggtgacgaacgtgcggccgcgctgggcgagttgctgaaggagcga ggcctgtcagtcgtcgcggtggaggccgaaggagcggaccgcgaggctctcgccgacgcg ctgcgcgcggctgccaccgatgcgttgcgcgcggctgcccccggtgcggagatcagcggc gtcctgtcgctgctggcgttcgacgagtcgccgcaccccgagcaccccgctgtgccgaat ggcgtcgcggccaccatcgcgctgttccaggcgctgggcgacaccgacgtacgggcgccg ctgtggtgcctgacgtcgggtgcggtgtcggcgaccgcggaggacgcggtcggcgggttc gcgcagtccatggtgtggggcctcggccgcgcagcggcgctcgaacaccccgaccgctgg ggcggcctcgtcgacctgccggaaacggtggacgaggccgcggccgcacggctgtgcggc ctcatcggcggagcggaggaccaggtcgccgtccgcgggaccggcgtgttcacgcgctgc ctgcggcgtgccggaagggccaccgcaagctcagggtggacgccgcgcggcacggtcctc gtgaccggcggtctcggcgccctgggtgccagggccgcacggtggctcgccgagcacggc gccgaacacgtcgtcctggtgagcaggcgcggccccgaggccgcgggcgccgccgaactg gacgccgaactcgccgagttgggcgcacgcgtcacggtcgccgccgtcgacatcgccgac agggaacggctcgccgccctgctcgacgacctggccgcggccggtgacccggtccgtgcc gtcgtgcacaccgccgggctcaacgacagcgtccccgccgacaccacggacctcgcgcgc ttcgccgacgtcgtcaccgccaaggtggcgggcgccgcgcacctgcacgaactcctggcc gacgcgccgctcgacgcgttcctgtcgtactcctcgatcgcgggcatctggggcagtggc ggccagctcgcctacagcgccgcgaacgcctacctcgacgcgctcaccgaacaccgtgcc gcccgcggcctgcccgccaccacggtggcctggggcccctgggcgggcggcggcatggcc gacgacgaggcgcagcggcagctgtcccggcgcggtctcctcgccctggcgcctgagctc gcggtgggcgccctcgccgacgcggtcggcggcggcacaccgagcacggtcgtcgtgaac gtcgactgggcgcggttcgcgcccgcgttcaccatcggcaggccgagcccgctgctcgcc gacctcgccgaggcgcgcgacgcgatcgcggaccgggccgacggagcaggcagggccgac gcctccgacaccggggacgagaagggcgccgcgctgcgcagccgcctcaccggtctggac gcggccaagcagaaggaactggtgcgcggcctcgtggccgccgaggccgccgccgtcctc gggcatgcctcggccgccgcggtcgaccccgaccgggccttccgcgaactgggcttcgac tcgctgaccgccgtcgaactccgcaaccggctgacggccgcctccggcctgacgctgccc gccaccgtggtcttcgactacccgagccccgcggtgctcgccgaacacctcctgacggag gtcgtcgcaccgcacggcgagtcgctcgtggcaccggcagccgcggcgccgggtgtgacc gacgagccgatcgcgatcgtcgcgatggcctgccgctaccccggcggcgtcgccaacccg gaggacctgtggcgggtgctgcgggagggcggcgacgcggtggcggagttccccgccgac cgcggctgggacatggagacgctgtacgaccccgaccccgaaggggtgggcaccacctac agccgcaggggcgccttcctcgaccgcgtcgcggacttcgacgcgagcttcttcggcatc tcgccgcgcgaggcgctcgccatggacccgcagcagcgcctgctcctcgaaacctcctgg gagaccttcgagcgcgccggtatggacccgaacgcgatccgcggcgagcgggtcggcgtg ttcgtcggctcgaacgtgcaggactacggcatggtcctggacggagccgccgaggacgtg ggcgggcacgtggcgacgggcagcgcggccagcgtcatgtccggccgcctctcgtacacg ttcggcctcgaaggccccgccgtcacggtcgacacggcctgctcgtcgtcgctcgtcgcg ctgcacctcgcggtgcaggccctccaccagggcgagtgcgagatggcgctcgcgggcggt gtgacggtgatgtcgacgccgggtgcgttcatcgagttcagccgccagcgcggcttgtcg gtcgacggccgctgcaaggcgttcgccgacgccgccgacggcacgggctggggcgagggc atcggcatgctgctcgtcgagcggctctccgacgccgagcgcaacggccaccaagtgctc gccgtcgtacggggttccgcggtgaaccaggacggcgcctccaacggcctgaccgcgccg aacggcccctcgcagcagcgcgtgatccgccaggcgctcgccagcgcgggtctcgccgcg tccgacgtggacgcggtcgaggcgcacggcaccggcacgaagctcggcgacccgatcgag gcgcaggcgctgctcgcgacgtacggccaggggcgcgacgccgaccggccgctgtggctc ggctcgatcaagtcgaacctcggtcacacccaggcggcggccggtgtggcgggcatcatc aagatggtcatggcgatgcgccacggcgtcctgccccgcaccctccacgtcgacgagccg tcgacacacgtggactggtccgcgggcgcggtgcggctgctcaccgacgagcgtgactgg cccgccgtggaccggccgtggcgggcgggtgtgtcctcgttcggcttcagcggcaccaac gcgcacaccgtcatcgagcaggccccccagacggcatcggccgaggcggaggccgacgcc gacgccggaccggcggagacgggcgtcgtgccgtgggtcctctcggcgcggtccgtggaa gcgctgcgggaacaggcggcccgcctccgcgacgagtgcgcgcacgagacggccgctccg gtcgccgacatcgcccactccctgcggacccgctccacgttcgaccgtcgggccgtcgtg gtgggccgcgaccgggaggacttcctctccgggctcaccgccctcgccgagggccgcgag gcacccaacgtcgtgaccggcgtcgcggaacaccacggcaccggaccggtgttcgtgttc cccggccacggcacgcagtggctcggcatggcgggcgacctcctggagtcgtcgccggtg ttccgcacacgtatgcaggagtgcgcggcggcactggcggagcacgtcgactggtcgctg ctcgacgcgatccacgacgacgccctgatggaacgcctcgacgtcgtccagcccgccctg ttcgcggtcatggtgtcgctggccgccacctggcggtcgtggggcgtcgagcccagcgcc gtactcggccactcccagggcgagatcgccgcggcctgcgtcgcgggcgccctgaccctc caggacgcggcacgcctggtcgtcgtccggagcaaggcgctgagcgccctttcgggacgc ggcggcatggtgtcggtcgcgctcgacgtggacggcgtacgggaactgatcgcgatctgg gcaggacagctcgcgatcggcgtggtcaacggacccgcctccgtcgtcgtctccggtgac gtcggcgcgctcgacgaactcgtcgagacctgcgccgagcagggcatctgggcgcgccgc gtgctcgccgactacgccccgcactcccaccacgtcgagcgcatcgaagccgacatcctg gcgggcctcgcggacgtcacgccgcgctccggcgacgtgccctactactcgccgctgacc ggcggctggctcgacacccgcgagctcgacgccgcgtactggtaccgcagcctgcggcag accgtcgagttcgccgactccgtcaccgacctcgtggcggcgggccacacggccttcgtc gaagtcagcccccacccggtcctggtggcggggctcggtgaactggtcggcgccgacggc gtcgtcgtcggctcgctgcgccgcggcgacggcggcctgacccgcctgacgacctcggcg agcggcctgttcgtccgcggcggacaggtggcctggccgacacccggcggacgccgcgtc gacctgccgacctaccccttccagcgcaagcgcttctggcccaccacgacgcacaccgcg accggcgacgtcacatcggcgggactcggccgcgtcgaccaccccgtgctcgccgccgtc accgaactcccggactccgagagcctcgtgttcagcggcaggctctccctgcgcacccac ccctggctcaccgactaccgcgtcctcggctccgcggtgctccccggcgccgcctacgtc gagctcgcgctgtgcgccggtgaccacgtcggctgcgcctccctggacgacctggtcctc gaagcacccctcgtactgcccgaacgcgacggcgtccaggtacggctcagcctgcacgga cccgacgactccgggcgacgggcgttcaccgtggactcccgcggcgacgagggcggcgac tggacccggcacgccacgggcgccctgaccgaccgggcggagcccgtcaccgacaccctc gtcgcctggccgcccagcgaggccgaaccggtcgacctggacacgcactactccgcggtc gccgcctccgggctcgaccacggccccgccttccagggcctcaacgcggcctggcgcaag ggcgacgaggtgttcgccgaagtggcgctgcccgaaggactcgcggacgacggcttcggc ctgcaccccgcactcctcgacaccgcgctgcacgccgtctcgctcggcgtcagctcggac gggctgccgttctcgtgggccggggtacggctcctggcgaccggcgcgaccgtgctgcgg gtccgtctcacgcccgtcggcgtggacgccgtggccgtactcgtcgccgacggcaccggc gagcccgtcgccgccgtcgacgagctgaacctgcggcccctgtcggccgaccagctcaac ctggcccggtccgcgcaccgcgactccctgttcgaggtgaagtgggtcccgacgcaggac gccgcccccgacaccggcacctgggcggtgctcggcgcgggaaccggcaccgaccgcctg gtccaggcgctcaccgccgccggtgagcaggtcgacgaacacgccgacctggccgccctt tcggccgccgtcgacagcggcgcgcccgcgccccgctacgtcaccgtgacccccggcggg gacgcggcgacaccccgcgaggccacgcaccacgccctcggcctgctgcaggactggctc gccgacgaccggttcgccgactccaggctcgtggtcctcaccagcggcgccgtcgccgcg ggaccggacgaggacgtacccgacctggtacgcgcccccgtgtggggcctggtccgctcg gcgcagtcggaacacccgacgcggttcgcgctcgtggacctcgtcgacacggacgacgac gcacggtcggcccgcaagctgcccgccgccgtggcgaccggggagccgcagctcgcgatc agggacggcgtcgcctcggtgccccgcctcgcccggctcgccgcgcacgccgacgcgccc gacacggtggccttcacccccgacagcgtggtcctgatcaccggtggactcggcgtgctc ggcggcgtgaccgcacggcacctcgtcacccgccacggcgtccgcgacctcgtcctgacc ggcaggcgcggcacggccacccccggcgcggacgaactgcgcgcggaactcgaggcactc ggcgcgcgggtcacggtcgccgcctgcgacgtgagcgaccgcgacgcggtcgccgcgctc ctcgcggagcaccccgtgaccgccctcgtgcacacggcgggcgtcctggacgacggcgtg atcggatccctcacacccgaacaggtcgacgcggtgctccgccccaaggccgacgccgca cgacacctgcacgagctgaccagggactccggcttcaccgcgttcgtgctgttctccgcg gcggccggtgtgttcggcggcccggggcagggcaactacgcggcggccaacgcctacctc gacgcgctcgcccagcaccgccgcgccgtgggactgcccgcgacgtcgctggcctggggc ctgtgggccgaggccaccggcatcaccgggcacctcgacgacgccgacgtccagcggatg gcgcggggcggcatggtcccgctgtccaccgcggacggcatggccctgttcgacgaggca cgcgcgaccggcgccgcgagcgcggtgcccgccgcgctcgacctggccgcgctccgggcc cacccggagcgggtgcggccgctgctgcgcggcctggtgcccaccccggcccgccggtcc gcgcggtccggcgacggcgcgggaacggtcccgctcgcccagcgcctcgcgggcctcacc gaggcggagcaggaccgggccctcgtacacctcgtgcgcacgcacaccgccgccgtactc ggcttcgcgggacccgacgcagtcgaggcggaccgggcgttcaaggagctcggattcgac tcgctgaccgccgtggaactgcgcaacaggctggacgccgaagtcgacacgcggctgccc gccaccctggtgttcgaccacccgacccccggggcgctcgcggcccatctgcggacgacg gtcgtcaccgaccaggcgtcgcccgcggcggccgtactcagcgaactcaacaagctcacg atcacgatgtccaagctcgacccggacgacgcactggccggagacatccggctccggctc cgctcgctcctttccacgtgggaggagcaggagcaggaagccgcggtggacgacctgagc tcggcaaccctcgatgacgtcttcgacatcatcgacgaggagctcggcaagtcctga

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