Streptomyces lydicus 103: SL103_29315
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Entry
SL103_29315 CDS
T04699
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
slc
Streptomyces lydicus 103
Pathway
slc00020
Citrate cycle (TCA cycle)
slc00630
Glyoxylate and dicarboxylate metabolism
slc00785
Lipoic acid metabolism
slc01100
Metabolic pathways
slc01110
Biosynthesis of secondary metabolites
slc01120
Microbial metabolism in diverse environments
slc01200
Carbon metabolism
slc01210
2-Oxocarboxylic acid metabolism
Module
slc_M00009
Citrate cycle (TCA cycle, Krebs cycle)
slc_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
slc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
SL103_29315 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
SL103_29315 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SL103_29315 (kgd)
Enzymes [BR:
slc01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
SL103_29315 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
SL103_29315 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
SL103_29315 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
SL103_29315 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AOP49800
UniProt:
A0A1D7VSR9
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All DBs
Position
6779798..6783589
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AA seq
1263 aa
AA seq
DB search
MSLQSPNSSSISTEADQEGQGKSPAAAFGPNEWLVDEIYQQYLQDPNSVDRAWWDFFADY
KPGGATAPSAPAEGSPGAADAVLPPAAAPDRSAPAAPAQPKPAAAAPATPAKPAASAPAP
AKPAAAKPAAKPAAAKETEAPEGPEYVVLRGPSAAVAKNMNASLELPTATSVRAVPVKLL
FDNRIVINNHLKRARGGKVSFTHIIGYAMVQALKAMPSMNYSFAQKDGKPTLVKPEHVNL
GLAIDLVKPSGERQLVVAAIKAAETMTFFEFWQAYEDIVRRARDNKLTMDDFTGVTASLT
NPGGIGTVHSVPRLMPGQSMIMGVGSMDYPAEFQGTSQDALNKLGVSKVMTLTSTYDHRV
IQGAASGEFLRIMNQLLLGENDFFDDIFKSLRIPYEPVRWLRDIDASHDDDVTKAARVFE
LIHSYRVRGHVMADTDPLEYHQRKHPDLDITEHGLTLWDLEREFAVGGFASKSMMKLRDI
LGVLRDSYCRTTGIEFMHIQDPKQRKWIQDRVERPHKSPEREEQLRILRRLNSAEAFETF
LQTKYVGQKRFSLEGGESVIPLLDAVIDSAAESRLDEVVIGMAHRGRLNVLANIVGKSYA
QIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQITVSLTANPSHLEAVDPVVEGV
ARAKQDIIGKGGTDFTVLPIQLHGDAAFAGQGVVAETLNMSQLRGYRTGGTVHVVINNQV
GFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEFRQAFNKDVVIDLI
CYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLEEAEQALQDFQGQL
EKVFTEVRDATTTPAVPEVPQPKAEFPVYVDTAISQEVVKRIAESQVNIPEHITVHPRLL
PQLQRRAAQVEDNTIDWGMGETLAVGSLLMEGTPVRLAGQDSRRGTFGQRHAVLIDRETG
EDYTPLLYLSEDQARFNVYDSLLSEYAAMGFEYGYSLARPESLVMWEAQFGDFVNGAQTI
VDEFISSAEQKWGQTSGVTLLLPHGYEGQGPDHSSARIERFLQLCAQNNMTVAMPTLPSN
YFHLLRWQVHNPHHKPLVVFTPKSMLRLKAASSKTEEFTTGGFRPVIGDASVKAEDVRKV
VFTSGKVYYDLDAERQKRGATDTAIVRIERLYPLPGKELQAEIAKFPNAEKYLWAQEEPA
NQGAWPFLGLNLIDHLDLAVGADVPHGERLRRISRPHSSSPAVGSAKRHQAEQAQLVAEV
FDA
NT seq
3792 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgctacagtcccccaacagctcgagcatctcgaccgaggccgatcaagaggggcag
ggcaagagccctgctgccgcattcggcccgaacgagtggctcgtcgacgagatctaccag
cagtacctccaggacccgaactcggtagaccgagcctggtgggacttcttcgccgactac
aagccgggcggcgccaccgcgccgagcgcaccggcggagggctcccccggtgcggctgac
gccgtgctgccccccgctgctgccccggaccggtcggctcccgccgcgccggcccagccg
aagcctgcagctgccgcgccggcgaccccggcgaagccggccgcgagcgctccggccccg
gccaagcccgccgccgcgaagccggccgcgaagccggccgccgcgaaggagaccgaggcc
cccgaaggccccgagtacgtcgtcctgcgcgggccctcggccgccgtggcgaagaacatg
aacgcctcgctggagctgccgacggccacgtccgtccgcgcggtcccggtgaagctgctg
ttcgacaaccgcatcgtcatcaacaaccatctgaagcgcgcccgtggcgggaaggtctcc
ttcacccacatcatcgggtacgcgatggtgcaggccctcaaggccatgccgtcgatgaac
tactccttcgcgcagaaggacggcaagccgacgctggtcaagcccgagcacgtcaacctc
ggtctggccatcgacctcgtgaagcccagcggtgaacgccagctggtcgtcgcggccatc
aaggcggccgagacgatgaccttcttcgagttctggcaggcgtacgaggacatcgtccgc
cgggcccgcgacaacaagctgacgatggacgacttcaccggggtcaccgcgtcgctgacg
aaccccggcggcatcggcaccgtccactccgtgccgcgtctgatgcccggccagtccatg
atcatgggcgtcggctcgatggactacccggcggagttccagggcacctcccaggacgcc
ctgaacaagctcggcgtctccaaggtcatgacgctgaccagcacgtacgaccaccgcgtg
atccagggcgccgcctccggcgaattcctgcgcatcatgaaccagctgctgctcggcgag
aacgatttcttcgacgacatcttcaagtcgctgcggatcccgtacgagccggtccgctgg
ctgcgggacatcgacgcctcgcacgacgacgacgtcaccaaggccgcccgggtcttcgag
ctgatccactcctaccgggtccgcggccacgtcatggccgacaccgacccgctggagtac
caccagcgcaagcaccccgacctcgacatcaccgagcacggcctcaccctgtgggacctg
gagcgcgagttcgcggtcggcggcttcgccagcaagtccatgatgaagctgcgcgacatc
ctgggcgtgctgcgtgactcgtactgccgcaccaccggcatcgagttcatgcacatccag
gaccccaagcagcgcaagtggatccaggaccgggtcgagcgtccgcacaagtcgcccgag
cgcgaggagcagctgcgcatcctgcgccggctgaactccgccgaggcgttcgagacgttc
ctgcagaccaagtacgtcggccagaagcgcttctcgctggagggcggcgagtccgtcatc
ccgctgctggacgcggtcatcgactccgcggccgagtcgcggctggacgaggtcgtcatc
ggcatggcccaccgcggccgcctcaacgtcctcgccaacatcgtcggcaagtcgtacgcg
cagatcttccgcgagttcgagggcaacctcgacccgaagtcgatgcacggctccggcgac
gtgaagtaccacctgggcgcggagggcaccttcaccggcctggacggcgagcagatcacc
gtctcgctcaccgccaacccctcccacctggaggccgtggacccggtcgtcgagggtgtc
gcgcgcgccaagcaggacatcatcggcaagggcggcacggacttcaccgtcctgccgatc
cagctgcacggtgacgcggcgttcgccggccagggcgtggtcgccgagacgctgaacatg
tcgcagctgcgcggctaccgcaccggcggcacggtgcacgtcgtcatcaacaaccaggtc
ggcttcaccgccgccccggagtcgtcgcgctcctccatgtacgccaccgacgtggcccgc
atgatcgaggcgccgatcttccacgtgaacggtgacgaccccgaggccgtcgtccgcgtc
gcccgtctggccttcgagttccgccaggcgttcaacaaggacgtggtcatcgacctgatc
tgctaccgccgccgcgggcacaacgagtcggacaacccggccttcacccagccgctgatg
tacgacctgatcgacaagaagcgctcggtgcgcaagctgtacaccgagtcgctgatcggc
cggggcgacatcaccctcgaagaggcggagcaggcgctccaggacttccagggccagctg
gagaaggtcttcaccgaggtccgtgacgccacgacgaccccggccgtgcccgaggtgccg
cagcccaaggcggagttcccggtctacgtcgacaccgcgatctcccaggaggtcgtcaag
cggatcgccgagtcgcaggtgaacatccccgagcacatcaccgtgcatccgcgtctgctg
ccgcagttgcagcgccgcgcggcccaggtcgaggacaacaccatcgactggggcatgggc
gagaccctcgccgtcggctcgctgctgatggagggcaccccggtccggctcgccggccag
gactcccgccgcggcacgttcggccagcgccacgcggtgctgatcgaccgggagaccggc
gaggactacaccccgctgctctacctgtccgaggaccaggcccgcttcaacgtctacgac
tcgctgctcagcgagtacgcggcgatgggcttcgagtacggctactcgctggcccgcccg
gagtcgctggtcatgtgggaggcgcagttcggcgacttcgtcaacggcgcccagacgatc
gtggacgagttcatctcctccgccgagcagaagtggggccagacgtccggcgtcaccctg
ctgctcccgcacggctacgagggccagggcccggaccactcctcggcccgcatcgagcgg
ttcctccagctgtgcgcgcagaacaacatgaccgtcgcgatgccgacgctgccgtcgaac
tacttccacctcctgcggtggcaggtgcacaacccgcaccacaagccgctggtcgtcttc
accccgaagtcgatgctgcgcctgaaggccgcgtcgtcgaagacggaggagttcaccacg
ggcggcttccgtcccgtcatcggtgacgcgtcggtcaaggccgaggacgtccgcaaggtc
gtcttcacctccggcaaggtctactacgacctggacgccgagcggcagaagcgcggcgcg
accgacaccgcgatcgtccgcatcgagcggctgtacccgctgcccggcaaggaactccag
gcggagatcgccaagttcccgaacgccgagaagtacctgtgggcgcaggaagagccggcg
aaccagggtgcctggccgttcctcggcctcaacctgatcgaccacctcgacctggccgtc
ggcgcggacgtgccgcacggcgagcgcctgcgccgcatctcgcggccgcactcctcgtcg
ccggccgtcggttccgccaagcgtcaccaggcggagcaggcacagctggtcgcggaggtc
ttcgacgcgtaa
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