Streptomyces lydicus A02: T261_2485
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Entry
T261_2485 CDS
T03756
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sld
Streptomyces lydicus A02
Pathway
sld00470
D-Amino acid metabolism
sld00550
Peptidoglycan biosynthesis
sld01100
Metabolic pathways
sld01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sld00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
T261_2485
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
T261_2485
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
T261_2485
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sld01011
]
T261_2485
Enzymes [BR:
sld01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
T261_2485
Peptidoglycan biosynthesis and degradation proteins [BR:
sld01011
]
Precursor biosynthesis
Amino acid ligase
T261_2485
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
Motif
Other DBs
NCBI-ProteinID:
AJT64164
LinkDB
All DBs
Position
complement(2701473..2702609)
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AA seq
378 aa
AA seq
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MSSQTSSHKPRVAVVFGGRSSEHGISVVTAGAVMRAIDREKYDVLPIGITTDGRWALTAD
DPERMAIADRQLPTVAALAESTEGGVVLPVDPTNREIVYTEPGSVPKALGEVDVVFPVLH
GPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKDYMKRVFTSFGLPVGPYEVIRPREWE
KDPAAARKKIVDFAGDHGWPLFVKPARAGSSIGITKVDGLAGLDEAIEEARRHDPKVIVE
ALLRGREIECGVLEFEDGPRASVPAEIPPVTAHDFYDFEAKYIDSADGIVPAPLTPEQTA
EVQRLAVEAFEAASCEGLVRADFFLQDNGEFVINEINTLPGFTPISMYPRMWQESGVSYP
ELIDRLLQAALTRSTGLR
NT seq
1137 nt
NT seq
+upstream
nt +downstream
nt
atgagcagccagacctcctcccacaagccccgcgtcgccgtcgtcttcggcggccgcagc
tccgagcacggcatctccgtggtcaccgccggcgccgtcatgcgcgccatcgaccgcgag
aagtacgacgtgctgcccatcggcatcaccaccgacgggcgctgggcgctgaccgccgac
gaccccgagcggatggccatcgcggaccggcagctgcccaccgtggccgcactcgccgag
tccaccgagggcggggtcgtgctcccggtcgacccgaccaaccgcgagatcgtctacacc
gagcccggctcggtgcccaaggccctcggcgaggtcgacgtcgtcttccccgtcctgcac
ggcccctacggcgaggacggcaccctccagggcctgctggagctctccggcgtcccctac
gtcggctcgggcgtcctcgcctccgccgtcggccaggacaaggactacatgaagcgggtg
ttcacctccttcgggctgcccgtcggcccgtacgaggtcatccgcccccgtgagtgggaa
aaggatcctgccgccgcccgcaagaagatcgtggacttcgccggcgaccacggctggccg
ctgttcgtgaagcccgcacgggccggctcgtcgatcggcatcaccaaggtcgacggcctc
gcgggcctggacgaggccatcgaggaggcccgccgccacgaccccaaggtcatcgtcgag
gcgctgctgcgcggccgcgagatcgagtgcggggtgctggagttcgaggacggcccgcgc
gccagcgtcccggccgagatcccgcccgtcaccgcgcacgacttctacgacttcgaggcc
aagtacatcgactcggccgacggcatcgtgcccgccccgctgacccccgagcagaccgcc
gaggtccagcggctggccgtcgaggccttcgaggcggcctcctgcgagggcctggtgcgc
gcggacttcttcctgcaggacaacggcgagttcgtgatcaacgagatcaatacgctgccc
ggcttcacgcccatctcgatgtacccgcggatgtggcaggagagcggcgtgagctacccg
gagctgatcgaccggctgctgcaggccgcgctgacccgctccacggggctgcgctga
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