Streptomyces leeuwenhoekii: sle_20960
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Entry
sle_20960 CDS
T04414
Symbol
sle_20960
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sle
Streptomyces leeuwenhoekii
Pathway
sle00470
D-Amino acid metabolism
sle00550
Peptidoglycan biosynthesis
sle01100
Metabolic pathways
sle01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sle00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
sle_20960 (sle_20960)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
sle_20960 (sle_20960)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
sle_20960 (sle_20960)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sle01011
]
sle_20960 (sle_20960)
Enzymes [BR:
sle01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
sle_20960 (sle_20960)
Peptidoglycan biosynthesis and degradation proteins [BR:
sle01011
]
Precursor biosynthesis
Amino acid ligase
sle_20960 (sle_20960)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
CQR61557
UniProt:
A0A0F7VVJ8
LinkDB
All DBs
Position
chromosome:complement(2579795..2580952)
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AA seq
385 aa
AA seq
DB search
MSTENLPQSPGQPTRKPRVAVVFGGRSSEHGISAVTAGAVLKAIDRTKYDVLPIGITRDG
RWALTADEPERMVITERRTPSVEDLAESTEGSVVLSVDPGSREVVYSEPGSVPKVLGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGSGVLASAVGQDKEYMKRVFTSFGLAVGPYVV
IRPREWQQDVSAARKKIVDFAGEHGWPLFVKPARAGSSIGITKVDDLSGLDEAIEEARRH
DPKILVEAALRGREIECGVLEFEDGPRASVPAEIPPPEAHAYYDFEAKYIDSTPGIVPAP
LTPEETAEVQRLAVEAFEAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPQMWQ
AGGVSYPELVDRLVQAALRRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaacctcccccagagccccgggcagccgacgcgcaagccgcgtgtggcc
gtcgtgttcggcgggcgcagctccgagcacgggatctccgcggtcaccgccggcgccgtc
ctgaaggccatcgaccggaccaagtacgacgtcctgccgatcggcatcacccgggacggc
cgctgggcgctcaccgccgacgagcccgagcgcatggtgatcaccgagcggcgcacgccc
agcgtcgaggacctggccgagtccaccgagggcagcgtggtgctctccgtcgaccccggc
agccgcgaggtcgtctacagcgagcccggctcggtgcccaaggtcctcggcgaggtcgac
gtcgtcttcccggtgctgcacggcccctacggcgaggacggcaccctccagggcctgctg
gagctgtccggtgtgccctacgtcggctccggggtgctcgcctcggcggtcggccaggac
aaggagtacatgaagcgggtgttcacctccttcgggctcgcggtgggcccgtacgtggtg
atccggccgcgcgagtggcagcaggacgtctcggccgcccgcaagaagatcgtcgacttc
gccggcgagcacggctggccgctgttcgtgaagcccgcgcgcgccggctcgtcgatcggc
atcaccaaggtcgacgacctgtccgggctcgacgaggcgatcgaggaggcccggcggcac
gacccgaagatcctcgtggaggccgcgctgcgcggacgcgagatcgagtgcggggtgctg
gagttcgaggacgggccgcgggcctccgtacccgccgagatcccgccgcccgaggcgcac
gcgtactacgacttcgaggccaagtacatcgactccacgcccggcatcgtgcccgcgccg
ctgacgcccgaggagacggccgaggtgcagcggctggcggtggaggcgttcgaggcggcc
tcctgcgaggggctggtgcgcgcggacttcttcctcaccgaggacggggagttcgtgatc
aacgagatcaacaccatgcccggcttcacgccgatctccatgtacccgcagatgtggcag
gccggcggcgtcagctatccggagctggtggaccggctggtgcaggcggcgctgcggcgc
tccacggggctgcgctga
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