Streptococcus mutans UA159 (serotype c): SMU_30
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Entry
SMU_30 CDS
T00100
Symbol
purL
Name
(GenBank) putative phosphoribosylformylglycinamidine synthase, (FGAM synthase)
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
smu
Streptococcus mutans UA159 (serotype c)
Pathway
smu00230
Purine metabolism
smu01100
Metabolic pathways
smu01110
Biosynthesis of secondary metabolites
Module
smu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
smu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
SMU_30 (purL)
Enzymes [BR:
smu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
SMU_30 (purL)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_linker
DJ-1_PfpI
GATase_3
Motif
Other DBs
NCBI-ProteinID:
AAN57819
UniProt:
Q8DWL5
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All DBs
Position
32584..36309
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AA seq
1241 aa
AA seq
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MDRRIFVEKKANFSIKSESLVKELTHNLQLTSLKILRIVQVYDIFNLEESLFARAQKHVF
SEQVTDTILDEATVQADLNSHAFFAIEALPGQFDQRAASSQEALLLLGSDSNVTVNTAQL
YLVNKDIDASELEAVKHYLLNPVDSRFKDITLPIRPQEFSNSDKTIPNLDFFKTYTAEDF
AAYKAEQGLAMEVDDLVFIQDYFKSIGRVPTETELKVLDTYWSDHCRHTTFETELKNINF
SASKFQKQLQTTYDKYIAMRDELGRSEKPQTLMDMATIFGRYERANGRLNDMEVSDEINA
CSVEIEVDVDGIKEPWLLMFKNETHNHPTEIEPFGGAATCIGGAIRDPLSGRSYVYQAMR
ISGAGDITAPIAETRSGKLPQQVISKTAAHGYSSYGNQIGLATTYVKEYFHPGFVAKRME
LGAVVGAAPKENVVREKPEAGDVVILLGGKTGRDGVGGATGSSKVQTVESVETAGAEVQK
GNAIEERKIQRLFRNGNVTRLIKKSNDFGAGGVCVAIGELADGLEIDLDKVPLKYQGLNG
TEIAISESQERMAVVVRPSDVDAFIAACHKENIDAVVVATVTEKPNLVMTWNGETIVDLE
RAFLDTNGVRVVVDANVVDKDVALPEVRTTSAATLEADTVKVLSDLNHASQKGLQTIFDS
SVGRSTVNHPIGGRYQITPTEASVQKLPVQNGVTTTASVMAQGFNPYIAEWSPYHGAAYA
VIEATARLVATGADWSRARFSYQEYFERMDKQADRFGQPVAALLGSIEAQIQLGLPSIGG
KDSMSGTFEELTVPPTLVAFGVTTVDSRQVLSPEFKTVGENIYYIPGQAISEDINFDYIK
ANFAQFEAIQAKHKVTAASAIKYGGVLESLALMSFGNHIGASVELTELDSSLTAQLGGFV
FTSDEAIADAVKIGQTVADFTVTVNGVNLSAAKLLAAFEGRLEEVYPTEFEQSTALEEIP
AVVSDAVIKAKERIAQPLVYIPVFPGSNSEYDSAKAFEQAGAKVNSVPFVTLNEAAIEAS
VDTMVDNIVKANIIFFVGGFSAADEPDGSAKFIVNILLNEKVCSAIDSFIERGGLIIGIC
NGFQALVKSGLLPYGDFEEVGETSPTLFYNDANQHVAKMVETRITNTNSPWLAGVKIGDI
HAIPVSHGEGKFVVTAEEFAELRDNGQIWSQYVDFDGKPSMDSKYNPNGSLNAIEGITSK
NGQIIGKMGHSERYENGLFQNIPGNKDQGLFESAVKYFTGK
NT seq
3726 nt
NT seq
+upstream
nt +downstream
nt
atggatagacgtatttttgttgagaaaaaagctaactttagcattaaatcggagtcactg
gtcaaagaactaacacataatttgcagttaacctccttaaaaattttacgtattgtgcag
gtttatgatatctttaatttagaagaaagcctgtttgcgcgtgcgcaaaagcatgtcttt
tctgagcaggtgacagatacaattttagatgaagcaactgtgcaggcggatcttaacagc
catgctttttttgctattgaagctttgccgggtcagtttgaccagcgggcagcaagttca
caagaagctttgctcttacttggtagtgacagcaacgtaacggttaatactgcccagctt
tatctggttaataaggatattgatgcatctgagttggaagcggtgaagcattatcttttg
aatccagttgattcgcgtttcaaagatatcaccttgcctattcgtccacaggaattttca
aattctgacaaaacaattccaaatttggatttctttaagacttatacagctgaagatttt
gcggcttacaaggcggaacaaggtttggctatggaagtggatgatcttgtttttattcaa
gattattttaaatcaattgggcgtgtgccaacagaaacggaattgaaagttttggatacc
tactggtctgaccactgccgtcacacgacttttgagacagaattgaaaaatattaacttt
tcagcttctaagttccaaaaacaattgcagacaacttatgataaatatattgccatgcgt
gacgaattgggacgttctgaaaagccacagacgcttatggatatggcgacaatctttggt
cgttatgagcgtgctaacggtcgtttgaacgacatggaagtgtcggacgaaatcaatgcc
tgctcggttgaaattgaggtagatgtagatggcatcaaagaaccttggctgctcatgttc
aaaaatgaaacccacaatcacccaacggaaattgagcctttcggtggagctgcaacttgt
attggtggtgctattcgtgacccattgtcaggtcgttcttatgtttaccaagctatgcgt
atatcaggtgcaggtgatattaccgcaccaatagcagaaacacgctctggtaaattgcca
caacaagtcatctctaaaacggcggcgcacggctattcgtcatacgggaaccaaatagga
cttgcgactacctatgtcaaagagtacttccatccaggcttcgttgctaagcgtatggag
ctaggtgctgttgtcggtgcagcaccaaaagaaaatgtcgtgcgtgaaaaaccagaagct
ggtgatgtggtcatccttcttggtggaaaaacaggacgtgacggtgtcggtggtgctaca
ggctcatctaaggttcaaacggttgaatcggttgagacagcaggtgccgaagtgcaaaaa
gggaatgctattgaagaacgtaagattcaacgtcttttccgcaatggcaatgtcactcgt
ctcatcaagaaatcaaatgattttggtgctggcggcgtctgtgtggctattggtgaattg
gcagatggtcttgaaattgacttggacaaagtgccactaaaataccaaggtcttaacggt
accgaaattgccatttctgagtcacaagaacgcatggctgttgttgttcgtccaagtgat
gtggacgcctttattgcagcatgtcataaagagaacattgatgcagttgttgtcgcgact
gttactgaaaaaccaaaccttgtcatgacttggaatggtgaaaccatcgttgacttggaa
cgtgccttccttgatactaacggtgtgcgtgtggttgttgatgcaaacgttgtggataag
gatgttgcccttcctgaggtgcgtacaacatcagcagcaacacttgaagcagacacagtg
aaagttctgtctgatcttaaccacgctagtcaaaaagggttgcaaactatctttgacagc
tcggttgggcgttcaacagttaatcatccaatcggcggtcgttatcaaattacgcctact
gaagcttctgtgcaaaaattgccagtacaaaatggtgtcacaacgacagcttctgtcatg
gcacagggattcaatccttatattgcggagtggtcaccttatcatggtgcagcttacgct
gttattgaagcaacagctcgcttggtagcaacaggtgctgattggtctcgtgcgcgtttc
tcttaccaagaatactttgaacgcatggataaacaagcggatcgctttggtcagccagta
gctgctctgcttggttcgatcgaggcacaaatccaacttggtttgccatcaatcggtggt
aaggactccatgtcagggacctttgaagaattgacggtaccgccaaccttggttgccttt
ggtgtgacaacagtagatagtcgtcaggttctttcaccagaattcaagactgttggtgag
aacatttactacatcccaggacaggctatttcagaagacattaattttgattatatcaag
gctaactttgcacaatttgaagccattcaagctaaacataaagtaacagcagcttcagct
attaaatacggcggtgttcttgaaagcctagcactcatgagctttggtaatcatattggt
gcttctgtagaattgacagagcttgacagcagcttgacagcgcagcttggtggttttgtc
tttacatctgatgaagccattgctgacgcagtgaaaattggtcaaactgtggcagacttt
acagtaactgtcaacggtgtcaacttgtccgctgcgaaattacttgcagcttttgagggc
aggttagaggaggtttacccaaccgaatttgaacagtcaacagctcttgaagaaatacct
gctgtggtatctgatgctgttattaaagctaaagaaagaattgcacagcctctggtttat
atcccagttttccctggttccaattcagagtacgattcagctaaggcctttgaacaagct
ggtgccaaagtcaactcagtgccatttgtgactcttaatgaagcagcgattgaggcttct
gttgacaccatggttgacaacattgttaaagccaatattatcttctttgtcggcggcttc
tcagcggcagatgagccagacggttcggctaagtttatcgtcaatatcttacttaatgaa
aaagtttgctctgctattgacagcttcattgaaaggggtggcctcatcatcggtatctgt
aatgggtttcaagctcttgtcaaatccggtcttctgccttatggtgactttgaagaagtt
ggtgagacaagcccaaccctcttctacaatgatgccaatcagcacgtggctaagatggta
gaaacccgtatcactaatactaactctccatggttggcaggtgttaagatcggtgatatc
catgcgattccagtctctcacggtgaagggaaatttgtcgtgacagctgaagaatttgcg
gaactgcgtgacaatggtcaaatctggagccaatacgtggactttgatggtaagccttct
atggattctaaatacaatccaaacggttcgctcaacgctattgaagggattacgagcaag
aacggtcaaatcattggtaagatgggacactcggaacgctatgaaaacgggctctttcaa
aacatcccaggtaacaaagatcaaggcctatttgaaagtgcagtgaaatactttactggg
aaatag
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