Salvelinus namaycush (lake trout): 120059037 Help Entry 120059037         CDS       T07522                                  Symbol ubr4 Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism snh  Salvelinus namaycush (lake trout) Brite KEGG Orthology (KO) [BR:snh00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:snh04121]     120059037 (ubr4) Enzymes [BR:snh01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      120059037 (ubr4) Ubiquitin system [BR:snh04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     120059037 (ubr4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 zf-UBR 7TMR-HDED Motif Other DBs NCBI-GeneID:  120059037 NCBI-ProteinID:  XP_038863730 UniProt:  A0A8U1ESS2 LinkDB All DBs Position Sna14:complement(2595261..2716083) Genome browser AA seq 5149 aa AA seqDB search MASSGGDGEPDWAADVRPLLSASYTAFETKELPQLIGSIINSESEILHHDKQYEPFYSSF VALSAHYITTVCGQIPRNQLLSVAAACKVLIEFSLLRLENPDEACAVSQKHLILLIKGLC TGCSRLDRTEIITFTAMMKSAKLPQTVKTLSDVEDQKEVLSPVNPELRHKEVQMNFFNQL TSVFNPDLTVLASPSGRTQAESESEDQATTDQTFQAKMKNAFVSQNVSSLQELGGSEKLL RVCLNLPYFLRYINRFQDAVSANSFFIMPATVGDATAVRNGFHSLVIDVTMALDTLSLPV LEPLTPGRLLDMTVLALSCLYAGVSVATCMAILQVGSGLQLRTASTSSKEEDYENDAATI VQKCLDIYEMIGQAISSSRRAGGEHYQNFQLLGAWCLLNSLYLILNLSPTALADKGKEKD PLAALRVRDIAARTKDGAGSPKLGPAKGHQGFGVLSVILANHSIKLLTSLFQDLQVEALH RVSAGWASDGPPAELNIMAQNTSTQRVQRLLDSVPLTNLLFNLLSTSYKKACVLQRQRKG SVSSDASASTDSNTYYEDDFSSTEEDSSQDDDSEPILGLWFEETISPTKDKVAPPPPPPP PPLETSPRLKSPSKQNAGENGNILAGRKDPELFLSLASSILNFITTSMLKSRNNFIRNYL SVSLTEQHMATLASIIKDVDKDVKGSSDEEFASALYLFNHTLVTSDLPSPALQNTLLQQL GVAPFSEGPWPLYINPQSLSVLSRVLLIWQHKASLQGDPDVPECITIWERFVGTLKQHTI QGSVPGDEDLNVEHLQLLLLLFHNLSERGRRAVLTLVTQAITELATLMNAQLRAVPLNLA RMLLVLDYLLHQYSKVPMYLFQQVQYNLLTPPWSGQGSVQDGSKRSALPLYCGFKEVEDN WSKHCSAGRIVQPKFYCVLSPEASEDDRSRLDSKVFQKLFNGAVKYNELYACLVSLLSAG SQFDTARRQENKPITPVEACSLQYYFLVLWRILGVLPPSKAYMEQLKDGQGEPSESDILH TLRWSSRLRVPTYVNWIKEHLVTQGMKADQATSLIEVASSRCSTVKYDVELAEDYIARQI SAFSCVDPSSILPLHQVPSLQAIYTLDAVISKVQVSLDEHFSKVAAETDPLKPSEITKNL LPATLQLIDLYTAFTRSYLLMSLPEEGENKLSEAKLQGYAAVLSIGSMRCKANLLGQNVM QNLPSAVQTLCETWNNIHTNEFPNIGSWRNAFANDTIPSESYISAIQTAHLGTLSNQSLA LASSLKHILLSLVRLTGDLIVWTEELNPPQVVHALLPLLLESSTESVAEICSTSLERILG PAESDTFLAHVYQRLVTGCYNIIANHSDPNSGLDESVLEECLQYLERQLESSQVCKAMED FFSFSGELVQIMMATANENLSAKFCNRVLKFFTKLFQLTEKSPNPSLLCLCGSLAQLACV EPSRLQSWLTRMTATPPKDSEHLETVQENRALLQVLTTHIVRDNSQVGEGVCTVLLSTLI PMATDMLANGDGAGFPELMVIMATLASAGQGAGHLQLHRAAIDWLTRCKKYLTQKNVVEK VSANVSQGKHASILECSCHIISYLADVMNALRQSSGQGSSVLLVDGEEKAVEVDSDWVDE LAVEDDDSQAEDSDEDSQCNKLCTFTITQKEFMNQHWYHCHTCKMLDGVGVCTVCAKVCH KDHEISYAKYGSFFCDCGAKEDGTCQALVKRSPSSGIGSAVKESSAFQSELRMPESAIRH QGSSDKGKVTICEGKPGDEDRPKKSSVCKNIEGCQEELLAQVSGSSTAAVVLEMLIFLMD AIQTNFQQASAVGSSSRAQQALNELHTQDKSVEMTDQLMVPTLGSQEGAFENVRMNYSGD QGQTIRQLISAHVLRRVAMCVLSSPHGRRQHLAVSHEKGKITVLQLSALLKQADSSKRKL TLTRLASAPVPFTVLSLTGNPCNEDYLAVCGLKDCHVLTFSSTGSVSEHLVLHPQLATGN FIIKAIWLPGSQTELAIITADFVKIYDLSVDALSPVYYFLLPSSKIRDATFLFNEEGKSI IVIMSSAGYMYTQVMDESSSAQHGPFYVTSVLEISHQDLKDSNGQVAGGGVSVYYSHVLQ MLFFSYSQGKSFAATVSRSTTDVQRLFTINVKGSNGGSKASPALCQWSEVMNHPGLVCCV QQTTGIPLVIMVKPDTFLIQEIKTLPAKAKIQDMVAIRHTASNEQQRTTMILLCEDGSLR IYMANVDNTSYWLQPSLQPCSGISIMKPVRKRKAAAATTRTSSQVTFPVDFFENNQQLTE VEFGGNDLLQVYNGQQIKHRLNSTGMYVANTKPGGFTVETVNNNVSMVMTGMRVQVGTQA IERAPSYLEIFGRTMQMNMTRPRWFDFPFTREEALQADKKLSLFFGASVDPAGVTMLDSI KIYGKTKEQFGWPDEPPEDFPSASVNNVCSPNLNTGNGTGEGDIAAPASTGGTVLERLVV SSLEALESCFAMGSSNEKEKNKAAALELATLLLSMATPSGVQQQTKGLLASLHTSRTAYH NHKDQSLLSNAVQCLNSCSRDSRDLDPELFQRLVITARCIAIMRPSNLVHFTETKPSSID TEMTEEGQKQMDSEGCNFIMQLVNNFWKLHALKPKNAFLAPACLPGLTHIEATVNALVDI IHGFCTCELDYINVASKIYMQMLLCPDTSVSFACKQALIRVLRPRNKRRHVTLPSPPRSN TPMGDKDDDDEDDVDDKMQPSGLTGGEGGRQESQEQGEVDHGDFEMVSESMVLETAENVN NGNPSPLEALLAGAEGFPPMLDIPPDADDETMVELAIALSLQQDQQGSSSSALGLQSLGL SGQAPSSSSLDAGTLSDTTASAPASDDEGSTAATDGSTLRTSPAEHGGSVGSESGGSAID SVAGEHSVSGRSSAYGDTTVEGHPAGPGSVSSSTGAISTTTAQQEGDGSDGDAETEGDIH TSNRLHMVRLMLLERLLQHLPQLDSVGGVHAIPYMQVVLMLTSDLDGEDDKDKGALDDLL ALLIAELGMHKKDVSKKNERSPINEVHLVIMRLLSVFMSRTKSGSKSSSESSSLISNSTA TALLSQGAIDYCLHVLKSLLEFWKSQQEEEESVAASQLLKPHTSSSPPDMSPFFLRQYVK GHAADVFEAYSQLLTEMVLRLPYQIKKIADTNPRIPPPVFDHSWFYFLSEYLMIQQTPFV RRQVRKLLLFICGSKEKYRQLRDLHTLDSHVRGIKKLLEEQGIFLRAGVVTATSGSALQY DTLISLMEHLKACAEIATQRTINWQKFCMKDDSILYFLLQVSFLVDEGVSPVLLQLLSCA LCGSKVLASSSSSSSGGGSGGTGTQSSQSKSSSKKSKKEDKEKDKEGDGVGSQEDQLCTA LVSQLNKFADKETLIQFLRCFLLESNSSAVRWQAHCLALHIYRNSSKSQQELLLDLTWAI WPELPAYGRKAAQFVDLLGYFSLKTPQTEKKLKEYSQKAVEILRTQNHILTTHPNSNIYS TLSGLVEFDGFYLESDPCLVCNNPEVPFSNIKLSSIKVDTRYTTTQQVVKLISSHTISKV TVKIGDLKRTKMVRTISLYYNNRTVQAIVELKNKPARWHKAKKVQLTPGQTEVKIDLPLP IVASNLMIEFSDFYENYQASSETLQCPRCSASVPANPGVCGNCGENVYQCHKCRSINYDE KDPFLCNACGFCKYARFDFMLYTKPCCAVDPIETEEDRKKAVTNINTLLDKADRVYHQLM GHRPQLESLLSKVNEAAPEKPQDDSGAGAGLGASSANVNRYIQQLAQEYSGDCKTSFDEL SKIIQKVLASRKELLEYDLQQREAATKSSRSSSHQPTFTASQYRALSVLGCGHTSSNKCY GCASAVTGHCITLLRALATNPALRQILGLQGLIRELFEYNLRRGTAAMREEVRQLVCLLT RDQPEATQQMNDLIIHKVSAALKGHWANPDLVSSLQYEMLLLTDSISKEGGCWELRLRCA LSLFLMAVNIKTPVVVENITLMCLRILQKLIKPPAPTSKKNKDSAVECLTTVKPYCNEIH AQAQLWLKKDPKASYEAWKKCLPARCQETAAKPQNKAEVRRRYLMEKYGWKWKQFMRSRS EGLFPRLLKLGHNNWLRQVLFTPATQAARQAACTIVEALTSIPSRKQQVLDLLTSYLDEL SIAGECAAEYLALYQKLIKPPQWKVYLAARGVLPYIGNLITKEIANLLALEEATLSTDLQ QGYALKSLTGLLSSFVEVESIKRHFKSRLVGTVLNGYLCLRKLVVQRTKLIDETQDMLLE MLEDMTTGTESETKAFMAVCIETAKRYNLDDYRTPVFIFERLCSIIYPEENEVTEFFVTL EKDPQQEDFLQGRMPGNPYSSNEPGIGPLMRDIKNKICQDCDLVALLEDDSGMELLVNNK IISLDLPVAEVYKKVWCPTNEGEPMRIIYRMRGLLGDATEEFIESLDSTTDEEEDEEEVY KMAGVMAQCGGLECMLSRLSGIRDFKQGRHLLTVLLKLFSYCVKVKINRQQLVKPDMNTL NVMLGTLNLALVAEQESKDSGGASIAEQVLSIMEIILDEANAEISEDKGNLLLTGDKDQL VMLLDQINTPFVRSNPSVLQGLLRIIPYLSFGELEKMRILVERFKPCCSFDKYDEEHSAD DKVFIDCFCKIAAGIKNNNNGHQLKDLILQKGITQSALGYMKKHIPNAKNLDADVWKKFL SRPALPFILRLLRGLATQHPPTQMLIGTDSITNLHKLEQVSSDEGIGTLAENLLEALREH AEVNLKIDAARRETRAEKKRMAMAMRQKALGTLGMTTNEKGQVVTKTSLLKQMEELIEEP GLTCCICREGYKFQPTKVLGIYTFTKRVALEDFENKPRKQQGYSTVSHFNIVHYDCHLAA VRLARGREEWESAALQNANTKCNGLLPVWGPHVPESAFATCLARHNTYLQECTGQREPTY QMNIHDTKLLFLRFATEQSFSVDTGGGGRESNIHLIPYIIHTVLYVLNTTRATSREEKNL QCFLEQPCEKWVESSYDVDGPHYYTVLAMHIQSPERWRSTRLAFLRRLLVSVHARKVSAV FTNKLSDKQSKEYAVYRSPLLFWGLVELIYDMFRKVPTSNTEGGWSFSLAEYVRHNDMPI YEASERVLKAYQEELMPAESFSEFLDVVGLLSDIPDPDFFLQDLLNSVP NT seq 15450 nt NT seq  +upstreamnt  +downstreamnt atggcgtcgagtggaggagatggagaaccggactgggctgctgatgtacggccgctttta tcagcttcgtacacagcttttgaaacgaaagagctacctcagcttataggatccataata aacagtgaatctgagatcctacaccatgataaacagtatgagccgttctactcgtccttc gtggcgctctctgctcattacatcaccacagtctgtggacaaatccccagaaaccagttg ctgtcagtagcagcagcatgtaaagtattgattgagttctcgctgctgcggctggagaac cctgacgaagcatgcgcagtctcacagaaacacctgatcctcttgataaaggggttgtgt accggctgcagccgcctggacagaacagagatcatcaccttcacagccatgatgaagtcg gccaaacttccccagaccgtcaagacactctccgacgtggaggaccagaaggaggtgctg tctccagtgaaccccgagctgcgacacaaggaagtacagatgaatttcttcaatcagctg acctctgtgttcaaccctgacctcaccgtgctggcctctccctcaggacgcacacaggcg gagagtgagagtgaggaccaggcgacgacagaccagaccttccaggccaaaatgaagaat gccttcgtgtcccagaacgtgtccagtctccaggaactgggcgggtcggagaagttgctg cgtgtctgcctcaacctcccttacttcctgcgctatatcaaccggttccaggacgcagtc tcagccaactccttcttcatcatgcccgccaccgtcggagacgcaactgctgtccgcaac gggtttcactcccttgtgatagatgtgaccatggccctggacaccttgtccttgcctgtc ctggagcccctgactcctgggagacttctggacatgactgtgctggcactcagctgcctc tacgcaggtgtgagtgttgccacgtgcatggccatcctgcaggtgggcagcggcctgcag cttcgcacagcctccaccagctccaaagaggaggactatgaaaatgacgctgctaccatc gtacagaaatgtctggacatctacgaaatgattggccaggccatcagcagctcccgcaga gccggaggagagcattaccagaacttccagctgctgggagcgtggtgtctgctgaacagc ctctacctgatcctgaacctgagtcccacggccctggctgacaagggcaaagagaaagac cctctggccgctctcagggtccgagacatcgccgcccgcaccaaggacggagctggctcc cctaaactgggccctgccaaaggacatcaaggctttggcgtcctgtcagtgatcctggct aaccactccatcaagctgctcacctctcttttccaagacctgcaggtggaggctctgcac cgggtcagtgcaggttgggccagtgacgggcccccagcagagctcaacatcatggcgcag aacacctccacccagagggtacagagactcctggactctgttccccttaccaacctgctg ttcaacctgctgtccacctcatataagaaggcctgtgtcctgcagcgccagaggaaaggc tcggttagcagtgatgccagtgcctcaacagactccaacacctactatgaagacgacttc agcagcacagaggaagacagcagccaagatgacgacagcgagcccatcttgggtctgtgg ttcgaggagaccatctcgccaactaaagacaaggtggcccccccaccgcctcccccaccc ccgcccctggagacctctcccagactgaagagcccctccaagcagaacgcaggagagaac ggaaacatcctggccggacgcaaggaccccgagctgttcctgagcctggcctccagcatc ctgaacttcatcaccacctccatgttgaagtccaggaacaactttatcaggaactacctg tctgtctccctgacagaacagcacatggccacgctggccagcatcatcaaggacgtcgac aaagacgtcaaaggttcctcagatgaagagtttgcctcggctctgtatctcttcaaccat accctggtgacgtcggacctaccttctccagccctgcagaataccctgctgcagcagttg ggcgtagctccgttctctgagggtccgtggcccctgtacatcaacccccagtccctgtcg gtgctctccagagtcctgctcatctggcagcacaaggcctctctgcagggagaccccgac gtacctgagtgtatcacgatctgggagaggtttgtgggcaccttgaaacagcacaccatc cagggctccgtccccggcgatgaggacctgaacgtggagcacctccagctcctgctgctc ctcttccacaacctgtctgagagggggaggcgcgccgtgctcaccctggtcacccaggcc atcacagagctagctacccttatgaatgcccagctcagagccgtacccctcaacctggcc cgcatgctgctggtgctagactacctgttgcaccagtactctaaggtccccatgtacctc ttccaacaggtccagtacaatctgctgaccccaccgtggtcaggccagggttccgtccag gacgggtccaaacgcagcgccctgccgctctactgcggctttaaagaggtggaggataac tggtccaagcactgctcggcaggtaggatagtgcagcccaaattctactgcgtcctgtca cctgaagcgtcagaggacgaccgaagccgactcgacagcaaggtgttccagaagctgttc aatggagcggtgaagtataatgagctttacgcctgtctggtctccctgctgtctgccggc tctcagtttgacacagccaggagacaggagaacaaacccatcacacctgtggaggcatgc tccctgcagtactacttcctggtgctgtggaggatcctgggagtcctacccccctctaag gcctacatggagcagctgaaggatggccaaggagaacccagcgagagtgacatcctccac accctgcgctggtcctcgcgactcagagtccccacatatgtcaactggatcaaggagcac ctggtgactcaggggatgaaggcagaccaagcgacgtctctgatcgaggtggcttcctcc aggtgcagcaccgtcaagtacgacgtggagctggccgaagactacatcgctagacagatc tcagcgttctcctgcgtggaccccagctccatcctgcctttgcatcaggtcccctcccta caggccatctatactctggacgccgtcatctccaaggtccaggtgtccctggacgaacat ttctctaaggtggcggcagagacagaccccctcaagccctcagagatcaccaaaaacctg ctgcctgctacactgcagctcatagacctgtacacagctttcaccaggtcctaccttctg atgagcctaccagaggaaggagagaacaagctatcagaggctaaactccagggttacgct gcagtgctgtctataggctccatgcgctgcaaagccaacctgctcggtcagaatgtgatg cagaacctgccatcggccgtccagacgctgtgtgagacctggaacaatattcacaccaac gagttccccaacatcggctcatggcgtaatgcgtttgccaacgacaccatcccgtccgag agctacatcagtgccatccagacggctcatctgggcacgctcagtaaccagtccctggcc ctggcctcctctctcaaacacattctcctctccctggtgcgcctcaccggagacctcatt gtgtggactgaggagttgaaccctccccaggtggtacatgctctgctccccctcctcttg gagagcagtacagagagcgtggctgagatctgctctacctctctggagcgtatcctgggc cccgcagagtcagacaccttcctggcccacgtctaccagaggctggtcacaggatgctac aacatcatcgccaaccactcagaccccaacagtggtctggacgagtctgtgttggaggag tgtctacagtatctggagaggcagctggagagcagccaagtgtgcaaggccatggaagac ttcttctccttcagtggagaactggttcagatcatgatggctacagccaatgaaaacctt tctgctaaattctgcaaccgggtgctgaaattcttcaccaaactcttccagctcacggag aagagtcccaacccaagcctgttgtgtctgtgtggctccctggcccagctggcgtgtgtg gagccgtccaggctacagtcgtggctcacccgcatgacggccacgccacccaaggactcg gagcatctggagacggtgcaggagaacagggcgctgctacaggtgctcaccacgcacatt gtcagggacaacagccaggtgggcgagggcgtgtgcaccgtcctgctctccaccctcatc cccatggcaacagatatgctggccaatggggacggcgctggcttcccggaactcatggtg atcatggcgaccctagccagcgccggtcagggggcggggcatctgcaactgcatcgcgct gccatcgactggctgaccagatgcaaaaagtacctgacccagaaaaacgttgtggagaaa gtgagcgcaaacgtgtcccagggcaaacatgccagcatactagagtgctcctgtcatatc atctcctacctggctgatgtgatgaacgccctgagacagagcagtggccagggctcctcc gtgctgctggttgatggagaggagaaggctgtagaggtggactcagactgggttgacgag ttggctgtggaggacgatgactcacaggctgaggactctgatgaagactcccagtgcaat aagctgtgtaccttcaccatcacccagaaggaattcatgaaccagcattggtaccactgt cacacgtgtaagatgctggacggggtaggtgtgtgtacagtgtgcgccaaggtctgtcac aaagaccatgagatctcctatgccaaatacggctctttcttctgtgactgcggggccaag gaggacggtacctgtcaggccctggtgaagcgcagccccagcagtgggatcggctctgcc gtgaaggagtcgtcagccttccagagtgaactgaggatgcctgagagtgccatccgccat cagggctctagcgacaagggcaaggtcaccatctgtgagggcaagcctggcgacgaggac cggcccaagaagagcagcgtctgtaagaacatcgagggatgccaggaggagctgctggcc caagtgtctggctcgtccacggcggcggtggttctggagatgttgatcttcctgatggat gccatccagactaacttccagcaggcctccgctgtaggcagcagcagccgagctcagcag gccctcaacgagctacacactcaggacaagagtgtcgagatgactgaccaactgatggtc cctacccttggttcccaggagggagcttttgagaacgtgcgtatgaactacagtggagat cagggtcagaccatcagacagctcatcagcgcccacgtgctgcgacgcgtcgccatgtgt gtgttgtcttcaccccacggccgtcgccagcacctcgccgtcagccacgagaagggcaag atcaccgtcctgcagctgtcggctcttctaaagcaagctgattccagcaagaggaagtta accctgactcgtctggcctcggcccccgtccccttcaccgtgctcagcctcactgggaac ccctgcaacgaagactacctggctgtctgtggactcaaggactgccacgtgctaacgttc agtagtacaggttccgtatcagaacacctggtgttgcaccctcagctggctactggaaac ttcattatcaaggccatctggctgcctggctcccagacggagctggccatcatcacggct gacttcgtcaagatctatgacctgtcagtggacgctctgagccccgtgtactacttcctg ctgccgagctccaagatccgtgacgccaccttcctgttcaacgaggaagggaagagcatc atcgtcatcatgtcctctgctggctacatgtacacacaggtcatggacgagtcgtccagc gcccaacacggacccttctatgttacctcagtcctggagatcagccaccaggaccttaag gacagtaacgggcaggttgctggcggcggtgtatcggtgtactacagccacgttctccag atgctgttcttcagctacagccagggcaagtcgtttgctgccaccgtcagccgcagcacc accgacgtacagagactcttcaccatcaacgtcaaaggctctaatggtggcagtaaggcg tctcccgctctgtgccagtggtctgaggtgatgaaccacccaggcctggtgtgctgcgtc cagcagactactggcattcctctggtcatcatggtcaaacctgacaccttcctcatccag gagatcaagaccctgcccgctaaagctaagatccaggacatggtagctatccgtcacaca gcgtctaacgagcagcagcgcaccacgatgatcctgctgtgcgaggacggctctctgagg atctacatggctaacgtagacaacacctcctattggctccagccctccctgcagccctgc tccggcatctccatcatgaagcctgtcaggaaacgcaaggctgctgctgccaccactcgt acctccagtcaggtgacgttcccggtggacttctttgagaacaaccagcagctgacggag gtggagtttggcggcaacgacctcctgcaggtttacaacggacagcagatcaaacacaga ctcaactccactgggatgtatgtagcaaacactaagccgggaggcttcacagtagagacg gtaaacaacaacgtctccatggtgatgacaggcatgcgggtgcaggtgggcacacaggcc atcgagcgggcaccttcttacctggagatctttgggcgaaccatgcagatgaacatgact cggccacgctggttcgacttccccttcaccagggaggaggctctgcaggcggacaagaaa ctctccctcttcttcggagcgtcagtggacccggcgggcgtcacaatgctggactctata aagatctatggtaaaaccaaggagcagtttggctggcctgacgagccccccgaggacttc ccctccgcctccgtcaacaacgtgtgctctcccaacctcaacaccggcaacggcaccggg gaaggggacatcgccgcaccagcctccaccggcggcaccgtgctggagaggttggtggtg agctctctggaagcactggagagctgtttcgctatgggctcctccaacgaaaaggagaag aacaaggctgcagccctggagctagccaccctcctcctgtccatggctactccctctggg gtccagcagcagaccaagggcctcctggccagcctgcacaccagccgtaccgcctaccac aaccacaaggaccagtccctgttgagcaacgccgtgcagtgtctgaacagctgtagtcgt gacagcagagacctggaccctgagttgttccagcgactggtcatcacggcacgctgcatc gccatcatgagacccagtaacctggtgcacttcactgagaccaaaccctctagtattgat acagagatgactgaggagggccagaaacagatggacagcgagggatgtaacttcatcatg cagctggtcaataacttctggaagctccatgccctcaaaccaaagaatgctttcctggct cctgcctgtctgccaggtctgacccacattgaagctacagtgaacgcattggtggacatc atccatgggttctgcacctgtgagctggactacattaacgtggcctccaagatctacatg cagatgctactgtgtcccgacacgtctgttagcttcgcctgtaagcaggccctgattcga gtgctccgacccaggaacaaacgccgtcacgtgactcttccgtctccccctcgctccaac acacccatgggagacaaagacgatgatgatgaggatgatgttgatgacaagatgcagccg tcggggctgacgggaggagaggggggcaggcaggagagtcaggagcagggtgaagtcgac catggcgactttgagatggtgtctgagtccatggttctggagacagcggagaatgtgaac aatgggaacccgtctcccctggaggctcttctggccggggccgagggcttccccccgatg ctggacatccctccagacgcggacgacgagaccatggtggagctagccatcgcactgagt ctccagcaagaccagcaaggcagcagcagcagtgccctaggtctccagtctctcggccta tcaggtcaggctcccagctcttcttctctggatgcaggcaccctgtcagacaccaccgca tcagccccagcatcagacgacgaggggagtacggccgccacggacggttctacgctacgg acctctccggccgagcacgggggcagtgtggggtccgagagcggggggtctgccatcgac tcagtggcaggagaacacagtgtgtcaggccgcagcagtgcgtacggggacacaaccgtc gagggccacccagcaggaccaggtagtgtgagctccagcacaggtgccatcagcaccacc acagcccagcaagagggcgatggatcggacggagacgcagagacagagggggacatccac accagcaacagactccacatggtgcgtctgatgctgctggagcgactcctacagcacctg ccccagctggacagtgtaggaggagtccacgctatcccctacatgcaggtggtcctgatg ctgacctctgacctggatggagaagatgacaaggacaagggagccctggacgacctgctg gctctactcatcgccgagctgggcatgcacaagaaggacgtgtccaagaagaatgagcgc agccccatcaacgaggtccatctggtcatcatgagattgctctctgtgttcatgtccaga accaagtctggatctaagtcttcctctgagtcgtcctctctgatctccaactccacggcc acagccctgctcagtcagggggcgatagactactgtctccacgtcctcaagtctctgctg gagttctggaagagccagcaggaagaggaggagtctgtggcagcctcccagctcctcaaa cctcacacctcctcctctcctccagacatgagccccttcttcctgaggcagtacgtcaag ggtcatgctgctgatgtgtttgaggcctactcccaacttctgactgagatggttctgaga ttaccctatcagatcaagaagatcgctgacaccaacccccgcatcccgcctcccgtcttc gaccactcctggttctacttcctgtctgagtacctgatgattcaacagacgcccttcgtg agacgccaggtcaggaagctgctcctgttcatctgtggttctaaggagaagtaccgtcag ctccgggacctgcacacgctggactctcacgtccgcggcatcaagaaactcctggaagaa cagggcatcttcctccgcgccggcgtcgtcacggcgacctccggctccgccctgcagtac gacacgctcattagtctgatggagcacctgaaggcctgtgctgagatagccactcagagg accatcaactggcagaagttctgtatgaaggatgactccatactgtactttctactgcag gtcagcttcctggtagatgagggagtgtctccggtgctcctccagctgctatcctgtgct ctgtgtggcagcaaggtcctggcttcctcttcctcctcttcctccggaggagggtctggg ggcactgggactcagtcctctcagagcaagtcctcaagcaagaagagcaagaaggaggac aaggagaaagacaaagaaggtgacggtgtgggtagccaggaggaccagctgtgtactgct ctggtctctcagctcaacaagtttgccgacaaagagactctcatccagttcctccgctgc ttcctgctcgagtccaactcctccgccgtgcgctggcaagcccactgtctcgcactgcat atctacaggaactccagtaagtctcagcaggagctgttgttggacctgacctgggccatc tggccagagctgcccgcctacggacgcaaggccgctcagtttgtagacctgctcggctac ttttccctgaagaccccccagactgagaagaagttaaaggagtattcccagaaagctgtg gaaatcctgaggacccagaaccacatcctgaccacccaccccaactctaacatctacagt accctgtcaggcctggtggagtttgatggtttctacctggagagtgatccctgtctggtg tgcaacaaccctgaagtgcccttctctaacatcaagctgtcgtccattaaggtggacact agatacactactacccagcaggtagtgaagctgatcagtagccacaccatcagtaaggtg acggtgaagataggagacctgaagagaaccaagatggtccggaccatcagcctctactac aacaacaggaccgtacaggccattgtagaactcaagaacaaacctgcccgttggcacaag gccaagaaggtccaactgactccaggtcagacagaggtcaaaatcgacctgccgctgcct atcgtggcgtccaacctcatgatcgagttctccgacttctacgagaactaccaggcctcc agcgagacgctccagtgtccgcgatgctctgcctccgtgcccgccaaccctggcgtctgt ggaaactgtggagaaaacgtctaccagtgccacaagtgcaggtccattaattatgatgag aaggatccctttctgtgcaacgcctgtggtttctgtaaatacgcccgctttgacttcatg ttgtacaccaagccctgctgtgctgtggacccaatcgagaccgaggaggacaggaagaag gcggtgaccaacatcaacacgctgctggacaaggctgaccgcgtgtaccaccagctgatg ggacacagaccccagctggagagtctgttgtccaaggtcaacgaggcagcgcctgagaaa ccacaggatgattctggagcaggggcggggcttggagcgtcctcggccaatgtgaacagg tacatccagcagctggctcaggagtacagcggagactgtaagacgtcctttgacgagctc tccaagatcatacagaaagtcctggcgtcccgtaaagaactcctggagtacgacctgcag cagcgtgaagccgccaccaagtcctctcgctccagctcccatcagcccaccttcacagcc agccaatacagagccctctctgtgttaggctgcggacacacctcctccaacaagtgttat ggctgtgcctcggccgtgacgggtcattgtatcaccctgctaagggccctggccaccaac ccagccctccggcagatccttgggctccaggggctcatcagagagctgtttgagtacaac ctgagaagaggtaccgctgccatgagggaggaggtcagacaactggtttgcctgctcacc agagaccagccagaggccactcagcagatgaatgacctgatcattcacaaggtgtccgct gctctgaagggccactgggccaatcctgacctggtctccagtctgcagtatgagatgcta ctgctcaccgactccatctccaaggaggggggatgctgggagctacgactgcgatgtgcc ctgagtttgttcctgatggccgtgaacatcaagacccctgtagtggtggagaacattact ctgatgtgtctcaggatcctacagaaactcatcaagcctcctgcccccacctccaagaag aacaaggattctgctgtggagtgtctgactacagtgaagccctactgcaatgagatccat gctcaggcccagctctggctcaagaaggaccccaaagcatcttatgaagcctggaaaaag tgccttccagcaagatgccaggagacggcagctaagccccagaacaaggctgaggtgcgg agacgctacctgatggagaagtacgggtggaagtggaaacagttcatgaggtcacgctcc gagggtctgttccccaggctcctcaaactgggacacaacaactggctcagacaggtgctg ttcaccccagccacccaggcagcgcggcaggcagcctgtaccatcgttgaggccctcacc tccatccccagccgcaagcagcaggtgctggacctgcttaccagttacctggacgagttg agcatcgcgggggaatgtgcagcagagtatcttgctctgtaccagaagctcatcaagcct cctcaatggaaggtgtacctggccgcccgaggagtcctgccctacatcggcaacctcatc accaaggaaatagccaacctgttggctctggaagaggccactctcagtacagacctgcag cagggatatgccctcaagagcttgactggcctactgtcgtcctttgtggaggtggagtcc atcaagcgccactttaagagtcgtctggtgggcacggtgctgaacggctacctgtgtctc aggaaactagtggtgcagaggaccaagctcatcgacgagacccaggacatgctgctggag atgctggaggacatgaccacagggaccgagtctgagaccaaggcattcatggcagtgtgt attgagacagccaagagatacaacctggatgactacagaacaccggtgtttatctttgag agactctgcagcatcatctacccagaggaaaatgaggtgacagagttctttgttaccctg gagaaggatcctcagcaggaggacttcctgcagggccgtatgcctggtaatccgtacagc agcaacgagccaggtatcggacccctgatgagggacatcaagaacaagatctgtcaggac tgtgacctggtggccctgctcgaggacgacagtggcatggagcttctggtgaacaataag atcataagtttggacctgcctgtggccgaggtttacaagaaggtgtggtgccctaccaac gagggagagcccatgaggatcatatatcgtatgaggggtctccttggagacgctactgaa gagttcattgagtctctggactctaccacagatgaagaggaggatgaggaggaggtgtat aagatggcaggagtgatggctcagtgtggtgggctggagtgtatgctcagcagactgtct ggcatcagggacttcaaacagggaagacacctgctcactgtgttgctgaagctgttcagt tactgtgtaaaggtgaagatcaacagacaacagctggtcaaaccagacatgaacacgctc aacgtcatgctgggcacactcaacctggcgttggttgcggagcaggagagtaaggacagt ggaggagcgtccatagcagagcaggtcctcagcatcatggagatcattctggatgaggcc aacgctgagatctcagaggacaagggtaacctgttgttaacaggggacaaggaccagctg gtgatgctgctggaccagatcaacaccccgtttgtccgttccaaccccagtgttctgcag ggtctcctacgtatcataccgtacctgtcctttggagaactggagaagatgaggatccta gtggagagatttaaaccatgctgcagcttcgacaagtacgatgaggagcacagtgccgat gataaggtcttcatcgactgcttctgtaagatcgctgctggcatcaagaacaacaacaac ggacaccaactcaaagacctgatcctgcagaaaggcatcacacagagcgccctgggctat atgaagaaacacatccccaacgccaaaaatctggatgctgacgtgtggaagaagttcctg tctcgtccagctctacccttcatcctcagactgctccgaggcctggccacccagcaccca cctacacagatgctaatcgggacagattccatcactaaccttcacaagctggagcaggtg tctagtgacgagggtattgggacgctggcagagaaccttctggaggcgctgagggagcac gctgaagtcaacctgaagatagacgccgctcgcagggagacacgggccgagaagaaacgc atggcaatggccatgagacagaaagctctggggacactgggcatgacgaccaatgagaag ggccaggtggtgaccaagacgtcgttgttgaagcagatggaggagctgatagaggagcca ggactgacctgctgcatctgtagagagggatacaagttccagccgaccaaggtgctgggg atctacaccttcaccaagcgagtggccctggaggactttgagaacaagccccgcaagcag cagggatacagcactgtgtcgcactttaacatagtccactacgactgccacctcgcagct gtcaggcttgctcgcgggcgggaggagtgggagagtgctgcgctgcagaatgccaacacc aagtgcaatggactgcttcctgtctgggggcctcacgtcccggaatcggctttcgccacc tgcctggccaggcacaacacatatctgcaggagtgtacggggcagagagagcccacctac cagatgaacatccacgacaccaagctcctcttcctgcgtttcgccacggagcagtccttc agcgtggatacgggagggggaggacgagagagcaacatccacctcatcccttacatcatc cacaccgtgctctacgtcctcaacactactcgggctactagtcgtgaggagaagaacctg cagtgtttcctggagcagccgtgtgagaagtgggtggagagcagctatgatgttgacggt ccccactactacacagtgttggccatgcacatccagtctcctgaacgctggaggagcaca cgactcgccttcctacgcaggctcctcgtctctgtgcacgcacgcaaggtctccgccgtc ttcaccaacaaactctcagataaacagtccaaggaatatgcagtgtaccgctctcctctc ctcttctggggccttgtggaactcatctatgacatgttcaggaaagtacccaccagcaac acagagggaggctggtccttctcgctggcagagtacgtgcggcacaatgacatgcccatc tacgaggcctcggagcgcgtgctcaaggcctaccaggaagaactcatgcccgctgaatcc ttctctgagttcctggatgtcgtaggacttctctctgacattccggacccagacttcttc ctgcaagacctgttgaactctgttccctga

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