KEGG   Streptomyces parvulus: Spa2297_23580
Entry
Spa2297_23580     CDS       T04685                                 
Name
(GenBank) D-alanine--D-alanine ligase A
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
spav  Streptomyces parvulus
Pathway
spav00470  D-Amino acid metabolism
spav00550  Peptidoglycan biosynthesis
spav01100  Metabolic pathways
spav01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:spav00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Spa2297_23580
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Spa2297_23580
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Spa2297_23580
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:spav01011]
    Spa2297_23580
Enzymes [BR:spav01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Spa2297_23580
Peptidoglycan biosynthesis and degradation proteins [BR:spav01011]
 Precursor biosynthesis
  Amino acid ligase
   Spa2297_23580
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N CPSase_L_D2 ATP-grasp ATP-grasp_4 ATPgrasp_ST
Other DBs
NCBI-ProteinID: ANJ09689
UniProt: A0A191V3W6
LinkDB
Position
5188402..5189559
AA seq 385 aa
MSTENLPQSPEQPPRKPRVAVVFGGRSSEHGISVVTAGAVLAAIDRTKYDVLPIGITRDG
RWALTADEPERMAITERRTPDVEELAESAEGAVVLPVDPANREVVYSEPGAVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKAVFASYGLKVGPYAV
IRPRDWEQDRSGARRRIVDFAAEHGWPLFVKPARAGSSIGITKVDDPAGLDEAIEEARRH
DPKILVEATLRGREIECGVLEFEDGPRASVPAEIPPPSEHAYYDFEAKYIDSTPGIVPAP
LTPEETAEVRRLAVAAFDAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPKMWE
ASGIGYPELVDRLVQAALRRPTGLR
NT seq 1158 nt   +upstreamnt  +downstreamnt
atgagcaccgagaacctcccccagagccccgagcagccgcctcgcaagccgcgtgtggcc
gtcgtgttcggcgggcgcagctccgaacacgggatctccgtggtcaccgccggcgccgtc
ctcgcggccatcgaccggacgaagtacgacgtcctgccgatcggcatcaccagggacggc
cgctgggccctcaccgccgacgagccggaacgcatggcgatcaccgagcgccgtacgccc
gacgtcgaggaactggccgagtcggccgagggcgccgtggtgctgcccgtcgaccccgcc
aaccgcgaagtcgtctacagcgaacccggcgcggtgcccaaggcgctgggcgaggtggac
gtcgtcttccccgtgctgcacggcccgtacggcgaggacggcaccctccagggtctcctc
gaactgtccggtgtgccctacgtcggcgcgggtgtgctcgcctcggccgtcggccaggac
aaggagtacatgaaggcggtgttcgcctcctacgggctgaaggtcggcccctacgcggtg
atccgtccccgcgactgggagcaggaccgttccggcgcccgccgcaggatcgtcgacttc
gccgccgagcacggctggccgctcttcgtgaagccggcccgggccggctcctcgatcggc
atcaccaaggtcgacgacccggccggcctcgacgaggcgatcgaggaggcccggcgccac
gacccgaagatcctggtcgaggcgaccctgcgcggccgcgagatcgagtgcggcgtgctg
gagttcgaggacggcccccgcgcctccgtccccgcggagatcccgccgccctcggagcac
gcgtactacgacttcgaggccaagtacatcgactccacccccggcatcgtgccggccccg
ctcacgcccgaggagaccgccgaggtgcggcgcctcgccgtggcggcgttcgacgcggcg
tcctgcgagggcctggtgcgcgcggacttcttcctcaccgaggacggcgagttcgtgatc
aacgagatcaacaccatgccgggattcacgccgatctcgatgtacccgaagatgtgggag
gcgagcggtatcggctaccccgagctggtggaccggctggtccaggcggcgctgcggcgc
ccgacggggctgcgctga

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