Streptococcus periodonticum: EHW89_04530
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Entry
EHW89_04530 CDS
T06568
Name
(GenBank) thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
spei
Streptococcus periodonticum
Pathway
spei00010
Glycolysis / Gluconeogenesis
spei00020
Citrate cycle (TCA cycle)
spei00620
Pyruvate metabolism
spei00785
Lipoic acid metabolism
spei01100
Metabolic pathways
spei01110
Biosynthesis of secondary metabolites
spei01120
Microbial metabolism in diverse environments
spei01200
Carbon metabolism
spei01210
2-Oxocarboxylic acid metabolism
Module
spei_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
spei00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EHW89_04530
00020 Citrate cycle (TCA cycle)
EHW89_04530
00620 Pyruvate metabolism
EHW89_04530
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EHW89_04530
Enzymes [BR:
spei01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EHW89_04530
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Trigger_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AZQ41764
UniProt:
A0A3Q9EYB3
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All DBs
Position
complement(929872..930840)
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AA seq
322 aa
AA seq
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MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVGEEAASVGAMLALNPDD
LITSNHRGHGQAIAKGIDLNGMMAEIMGKYNGTCKGKGGSMHIADLDAGNLGANGIVGGG
MGIAVGAALTQQMHQTDKIVVCFFGDGATNEGVFHEAVNMASIWNLPVIFYCINNGYGIS
ADIKKMTNVEHIHERSAAYGIPGMFIEDGNNVLDVYEGFQKAVEHVRSGKGPVLIESVTY
RWLGHSSSDPGKYRTREEVEEWKKKDPIENLRKYLLANQIASNEELEAIQAEVKEAIEAS
VKFAEESPFPPLESAFEDIYAD
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atgtcaactttagataaaaatcttttgctagagatgtttcgtaagatggaagagatccgt
cggatggacttaaaaattgcccaactcgtaaaaaaggggaaagttccaggaatgactcac
ttttctgttggagaagaagcagctagcgttggagctatgctggccctcaatcctgatgat
ttgattacttctaaccaccgtggtcatggtcaggcgattgccaaaggaattgatctgaac
ggcatgatggcagaaatcatgggcaaatataacggaacctgcaaaggaaaaggtggctcc
atgcacattgctgatttggatgccggaaacttaggagcaaatggtatcgttggcggaggc
atgggaattgcagtcggtgccgccctcactcagcaaatgcaccaaacagataaaatcgtg
gtttgcttctttggtgacggagcaacgaacgaaggtgtcttccacgaagcagtcaacatg
gcttctatctggaatctaccagtaattttctattgtatcaataacggctatggtatttct
gcagacattaagaaaatgaccaatgtagaacacatccacgagcgcagcgcagcttatggt
attccaggtatgttcattgaagatggcaataatgttttggatgtctatgaaggtttccaa
aaagctgtagagcatgttcgcagtggtaaaggacctgtcttaatcgagagtgtgacctat
cgttggttgggacattcatcttctgacccaggtaaataccgtactcgtgaagaagtagaa
gaatggaagaaaaaagatccaatcgaaaatcttcgtaaatatttactcgcaaatcagatt
gcaagcaatgaagaattagaagctatccaagcggaggttaaagaagcaatagaagcatct
gtaaaattcgcagaggaaagtccattcccaccgcttgagtcagcttttgaagatatttac
gcggactaa
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