Streptococcus pyogenes MGAS10270 (serotype M2): MGAS10270_Spy1229
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Entry
MGAS10270_Spy1229 CDS
T00355
Symbol
ddlA
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sph
Streptococcus pyogenes MGAS10270 (serotype M2)
Pathway
sph00470
D-Amino acid metabolism
sph00550
Peptidoglycan biosynthesis
sph01100
Metabolic pathways
sph01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sph00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
MGAS10270_Spy1229 (ddlA)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MGAS10270_Spy1229 (ddlA)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
MGAS10270_Spy1229 (ddlA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sph01011
]
MGAS10270_Spy1229 (ddlA)
Enzymes [BR:
sph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
MGAS10270_Spy1229 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:
sph01011
]
Precursor biosynthesis
Amino acid ligase
MGAS10270_Spy1229 (ddlA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
ABF34294
UniProt:
Q1JG50
LinkDB
All DBs
Position
complement(1187184..1188230)
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AA seq
348 aa
AA seq
DB search
MSKQTLVLLYGGRSAEREVSVLSAESVMRAVNYDKFLVKTYFITQMGQFIKTQQFSEKPS
ESERLMTNETIELTQKIKPSDIYEEGAVVFPVLHGPMGEDGSIQGFLEVLRMPYIGTNVM
SSSIAMDKITTKRVLESIGIPQVAYTVYIDGQDLEACLVETLARLTFPIFVKPANMGSSV
GISKAQTKVELRKAIQLALTYDSRVLIEQGVVAREIEVGLLGNDKVKSTLPGEVIKDVDF
YDYQAKYVDNKITMAIPADVDQSIVTEMRSYAEVAFKALGGCGLSRCDFFLTQDGQVYLN
ELNTMPGFTQWSMYPLLWENMGLAYPDLIEVLVTLAQEMFDQRESHLI
NT seq
1047 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaacaaacgttagttctattatacggaggccgctcagcagaacgtgaagtctca
gtgctttcagcagagagtgtgatgcgagcagtcaactatgataagttcttagtaaaaact
tattttattactcagatgggccaatttatcaaaactcagcaattttcagaaaagccatcg
gaatcagaacgcttgatgacaaatgagacgatagagctaactcaaaaaataaaaccaagt
gatatctatgaagaaggtgcagttgtatttcctgtattacatggacctatgggagaagat
ggctctatccaaggtttcttagaagtgcttagaatgccatatatagggactaatgtcatg
tcttctagcatagctatggataaaattactactaaacgtgtcttagaatcaattggaatt
ccacaagttgcctatactgtttatattgacggacaagatttggaggcttgtttagttgaa
actttagcaagacttacttttcctatcttcgtaaaaccagctaatatgggttcttctgtg
gggatttccaaagcccaaacaaaagtagaattaagaaaagcgattcagttagccctgacc
tatgacagtcgtgtcttgattgaacaaggcgtggttgccagagaaattgaagttggtctc
cttggaaatgataaggttaaatcaactctcccaggagaagtaatcaaggacgttgatttt
tacgactaccaagcaaaatatgttgataataagattacgatggccattccagcagatgta
gatcagagtattgtgacagaaatgcgttcttatgctgaagtagcctttaaagccttaggt
ggttgcgggttgtcccgttgtgactttttcttgacccaagacggacaggtttaccttaac
gaattaaacaccatgccaggctttacccaatggtctatgtatccactcttatgggaaaat
atgggattggcttatccagatttgattgaagtgctggtgacactggcacaagaaatgttt
gaccagcgtgagagccatctgatttaa
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