Streptococcus pneumoniae gamPNI0373 (virulent serotype 1): HMPREF1038_01349
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Entry
HMPREF1038_01349 CDS
T02334
Symbol
hom
Name
(GenBank) homoserine dehydrogenase
KO
K00003
homoserine dehydrogenase [EC:
1.1.1.3
]
Organism
spng
Streptococcus pneumoniae gamPNI0373 (virulent serotype 1)
Pathway
spng00260
Glycine, serine and threonine metabolism
spng00270
Cysteine and methionine metabolism
spng00300
Lysine biosynthesis
spng01100
Metabolic pathways
spng01110
Biosynthesis of secondary metabolites
spng01120
Microbial metabolism in diverse environments
spng01230
Biosynthesis of amino acids
Module
spng_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
spng_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
spng00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
HMPREF1038_01349 (hom)
00270 Cysteine and methionine metabolism
HMPREF1038_01349 (hom)
00300 Lysine biosynthesis
HMPREF1038_01349 (hom)
Enzymes [BR:
spng01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
HMPREF1038_01349 (hom)
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Motif
Pfam:
Homoserine_dh
NAD_binding_3
ACT
GFO_IDH_MocA
PASTA
Motif
Other DBs
NCBI-ProteinID:
AFS43381
LinkDB
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Position
complement(1244243..1245562)
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AA seq
439 aa
AA seq
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MAILENFEEIKMTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVKDEDEK
NRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVVTANKDLL
AVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVNGTSNFMVTK
MVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMKIAFDDVAHKGI
RNITPEDVAVAQEFGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLASVNGVMNAVFVES
IGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEYSRDLVLANPEDVKAN
YYFSILAPDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARVVIITHKINKAQLENVSA
ELKKVSEFDLLNTFKVLGE
NT seq
1320 nt
NT seq
+upstream
nt +downstream
nt
atggctatattagaaaatttcgaggagataaagatgacagttaaaattgctttactagga
tttggtaccgttgcaagtggtgtgcctttcctcctaaaggaaaatggaggaaaaatcaat
caatcagcacattcagatatcaaagttgctaaggtattggtcaaggatgaagatgaaaaa
aatcgcttgcttgcagcagggaatgactttaactttgtaaccaatgtggatgatatttta
tcagaccaggatattactatcgtagtggaattgatggggcgtattgagcctgctaaaacc
tttattactcgtgccttggaagctggaaaacacgttgttactgctaacaaggacctttta
gctgtccatggcgcagaattgctagaaatcgctcaagctaacaaggtagcactttactac
gaagcagcagttgctggtgggattccaattcttcgtactttagcaaattccttggcttct
gataaaattacgcgcgtgcttggagtagtcaacggaacttccaacttcatggtgaccaag
atggtggaagaaggctggtcttacgatgatgctcttgcggaagcacaacgtctaggattt
gcagaaagcgatccgacgaatgacgtagatgggattgatgcagcctacaagatggttatt
ttgagccaatttgcctttggcatgaagattgcctttgatgatgtagcccacaagggaatc
cgcaatatcacaccagaagacgtagctgtagctcaagagtttggttacgtagtgaaattg
gttggttctattgaggaaacttcttcaggtattgctgcagaagtgactccaaccttccta
cctaaagcgcacccacttgctagtgtgaatggcgtaatgaacgctgtctttgtagaatct
atcggtattggtgagtctatgtactacggaccaggtgcgggtcaaaaaccaactgcaaca
agtgttgtagctgatattgtccgtatcgttcgtcgtttgaatgatggtaccattggcaaa
gacttcaacgaatatagccgtgacttggtcttggcaaatcctgaagatgtcaaagcaaac
tactatttctcaatcttggctccagactcaaaaggtcaggtcttgaagttggctgaaatc
ttcaatgctcaagatatttcctttaagcaaatccttcaagatggcaaagagggtgacaag
gcgcgtgtcgttatcatcacacacaagattaataaagcccagcttgaaaatgtctcagct
gaattgaagaaggtttcagaattcgacctcttgaataccttcaaggtgctaggagaataa
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