KEGG   Caldimonas thermodepolymerans: IS481_14115
Entry
IS481_14115       CDS       T06911                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
sthm  Caldimonas thermodepolymerans
Pathway
sthm00470  D-Amino acid metabolism
sthm00550  Peptidoglycan biosynthesis
sthm01100  Metabolic pathways
sthm01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sthm00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    IS481_14115
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    IS481_14115
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    IS481_14115
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sthm01011]
    IS481_14115
Enzymes [BR:sthm01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     IS481_14115
Peptidoglycan biosynthesis and degradation proteins [BR:sthm01011]
 Precursor biosynthesis
  Amino acid ligase
   IS481_14115
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp_3 ATP-grasp GARS_A CPSase_L_D2 ATPgrasp_ST ATP-grasp_4 RimK ATP-grasp_5 TTL
Other DBs
NCBI-ProteinID: QPC30870
LinkDB
Position
complement(2997226..2998182)
AA seq 318 aa
MKLDLASIDPKALGKVAVLMGGHSAEREVSLMSGQGVLDALTSQGVDAHAFDPAERSLDE
LRRDGFDRCFIALHGRFGEDGTVQGALELLHVPYTGSGVMASAIAMDKIMTKRIWRFEGL
PTPDWRLVSSADETRAALAALGAPMIVKPSREGSTIGLTKVTSVEQCDAAFELAARCDPL
VLCEEFIEGDETTCPVLGEGAAAEALPLIRIVAPEGNYDYQNKYFTDVTQYHCPSGLPEA
EEREIQRIVVQAYRTLGCSGWGRADVMIRKKDRKPFLLEMNTSPGMTGHSLVPMSARAAG
ISYEQLCLWLVAQASLKL
NT seq 957 nt   +upstreamnt  +downstreamnt
atgaaactggatctcgcctccatcgacccgaaggcgctcggcaaggtggccgtgctgatg
ggcgggcattcggccgagcgcgaggtgtcgctgatgtccggccagggcgtgctggacgcg
ctgacctcgcagggcgtggacgcacatgccttcgacccggccgagcgcagcctggacgag
ctgcgccgcgacggcttcgaccgctgcttcatcgcgctgcacggccgtttcggcgaggac
ggcacggtgcagggcgccctcgagctgctgcacgtgccgtacaccggctcgggcgtgatg
gcctcggccatcgcgatggacaagatcatgaccaagcgcatctggcgcttcgagggcctg
cccacgcccgactggcggctggtgtccagcgccgacgagacgcgcgcggcgctggccgcg
ctcggcgcgccgatgatcgtcaagccctcgcgagaaggctcgaccatcgggctgaccaag
gtcaccagcgtcgagcagtgcgacgcggccttcgagctggccgcgcgctgcgacccgctg
gtgctgtgcgaggagttcatcgagggcgacgagaccacctgcccggtgctgggcgagggg
gcggcggccgaggcgctgccgctgatccgcatcgtcgcgccggaaggcaactacgactac
cagaacaagtacttcaccgacgtcacgcagtaccactgcccgagcggcctgcccgaagcc
gaggagcgagagatccagcgcatcgtcgtgcaggcctaccgcacgctcggctgcagcggc
tggggacgtgccgacgtgatgatccgcaagaaggaccgcaagcccttcctgctcgagatg
aacacctcgccgggcatgaccggccattcgctggtgccgatgtcggcgcgcgcggcgggg
atcagctacgaacagctgtgcctgtggctggtggcccaggcctcgctgaagctctga

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