KEGG   Sphaerobacter thermophilus: Sthe_1990
Entry
Sthe_1990         CDS       T01128                                 
Name
(GenBank) D-alanine/D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
sti  Sphaerobacter thermophilus
Pathway
sti00470  D-Amino acid metabolism
sti00550  Peptidoglycan biosynthesis
sti01100  Metabolic pathways
sti01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sti00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    Sthe_1990
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    Sthe_1990
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    Sthe_1990
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sti01011]
    Sthe_1990
Enzymes [BR:sti01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     Sthe_1990
Peptidoglycan biosynthesis and degradation proteins [BR:sti01011]
 Precursor biosynthesis
  Amino acid ligase
   Sthe_1990
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 MCR_beta_N
Other DBs
NCBI-ProteinID: ACZ39420
UniProt: D1C5A3
LinkDB
Position
1:complement(2209466..2210593)
AA seq 375 aa
MAQGARKIRVGVIFGGRSGEHDVSLRSAQAILRAIDRERFEVVPIGITREGRWLSGGDPL
RQLAATSRLALAPGDDPPAEESDLGSALAVPETGHAVEVAGAGVVQQLDVVFPVLHGPYG
EDGTVQGLLELADVPYVGAGVLGSAVSMDKVVAKQLFEREGLPVAPWLWVTRRQWERDPE
GVAARVERELGYPCFVKPANLGSSVGVSKVHHPGELPGAMEEAARYDRKLVVERGIDARE
LEVSVLGNDEPITSVVGEIRPVNEFYDYQAKYVDEGSELLVPAPITQEQSDTVREMAVRA
FKVVDAAGMARVDFFLERNTGTIYINEINTIPGFTQISMYPILWEASGLSFRELVSRLIE
LALERHAERRDGSGV
NT seq 1128 nt   +upstreamnt  +downstreamnt
gtggcacagggcgccaggaaaattcgcgtcggtgtcatctttggcgggcgctcgggcgag
cacgacgtgtcgctgcgctccgcgcaggccatcctgcgggcgatcgaccgggaacggttc
gaggtcgtgcccatcggcatcacacgggagggccgctggttgagcggtggtgacccgttg
cggcagctcgccgccacctcgcgcctggctcttgcgccgggggacgacccgccggcggag
gagtccgacctcggcagcgcgctggccgtgccggagacgggccacgccgtcgaagtcgcc
ggtgccggtgtcgtgcaacagctcgatgtcgtcttcccggtcctgcacggcccgtacggt
gaggacggcacggtgcagggtctgctggagctggccgatgtcccctacgtcggcgccggg
gtgctcggctcggcggtctcgatggacaaggttgtagccaagcagctcttcgagcgtgaa
ggcttgccggtcgcgccctggctgtgggtgacccgccgccagtgggaacgcgacccggaa
ggcgtggcagcgcgggtcgagcgggaactgggctatccctgcttcgtcaagcctgccaat
ctcgggtcaagtgtcggcgtcagcaaggtgcatcacccgggagagcttcccggggcgatg
gaggaagccgcgcgctacgaccgcaagcttgtcgttgagcgggggatcgacgcgcgcgag
ctggaggtgagcgtcctcggcaacgacgagccgatcacctcggtcgtgggcgagatccgg
ccggtcaacgagttctacgactaccaggccaagtacgtcgatgagggctcggagttgctc
gtcccggcgccgatcacgcaggagcagtccgacacggtgcgcgagatggcggtgcgcgcc
ttcaaggtcgtggacgccgccgggatggcgcgcgtggacttcttcctggagcgaaacacc
ggcaccatctacatcaacgagatcaataccatcccgggcttcacccagatcagcatgtac
cccatcctctgggaggcaagcggattgtccttccgggagctggtttcccggctgatcgag
ctggcgctggagcggcacgccgagcgccgcgacggcagcggggtatga

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