Spirochaeta thermophila DSM 6578: Spith_0613
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Entry
Spith_0613 CDS
T02016
Name
(GenBank) D-alanine--D-alanine ligase domain protein
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
stq
Spirochaeta thermophila DSM 6578
Pathway
stq00470
D-Amino acid metabolism
stq00550
Peptidoglycan biosynthesis
stq01100
Metabolic pathways
stq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stq00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
Spith_0613
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Spith_0613
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Spith_0613
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
stq01011
]
Spith_0613
Enzymes [BR:
stq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
Spith_0613
Peptidoglycan biosynthesis and degradation proteins [BR:
stq01011
]
Precursor biosynthesis
Amino acid ligase
Spith_0613
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Methyltransf_25
Methyltransf_31
Methyltransf_11
Ubie_methyltran
Methyltransf_23
Methyltransf_12
ATPgrasp_Ter
MTS
TehB
ATP-grasp_4
ATP-grasp_3
Cons_hypoth95
Methyltransf_29
MetW
TTL
FtsJ
Motif
Other DBs
NCBI-ProteinID:
AEJ60893
UniProt:
G0GA57
LinkDB
All DBs
Position
713385..715331
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AA seq
648 aa
AA seq
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MIEEKTQETDKPPERRRRRIPAARARCLGPLSDLESHVAPDWWSRIFNSYYMKTDGDVVD
DLAITRKEDDLFTSVLGLKKEEVVLDLCCGQGRHSLELARRGFTRVEGLDRSHYLIQRAK
AQAAKEGLPVKFREGDARKLPYPPDQFDVVMILGNSFGYFESSKDDLLVLKEVARVLKPW
GRILLDLADGEYLRAHYVPRSWEWIDAKHFVCRERALSADRQRLISREVIVHTEKGVEVD
QFYAERLYTPELIRSLLEEAGFQEVSFHGSLTPDSARGQDLGMMERRILVSARIRKEWAP
VKSRKKNVSTQVAVVMGDPSKPDPLKPFMVFDDDDLYTIDRLKAALKECTGYSFTYLSRH
ETLIQDLMRLKGKVDYVFNLCDEGFFNDPRKELHVPALLEMLGIPYTGATPQGLAFCYDK
SLVRGVAKEMGVPVPRAFFIDPTSIVFEVPFGFPMIVKPNLGDSSFGITQKSVVWSLDEL
SACISEIRDTFGYEKPVLVEEFLTGKDLTVGIIGNPTDDYMVLPIVEEDYSALPPELPRI
CGYEAKWLPDSPYWKALRSIPAGLPEETEKSIVEWCVRLFERLECRDYARFDWRCDADGN
PYLLEVNPNPGWCWDGHLAKMARLAGMEYPRMLEAILKAAEKRLGIRS
NT seq
1947 nt
NT seq
+upstream
nt +downstream
nt
atgatagaagagaagacccaggagacagacaagcctccggaacggaggcgaagacggatc
cctgccgcacgggcccggtgtcttggtccgctttccgatctggaatcccacgtggccccg
gactggtggtccaggatcttcaactcctactacatgaagaccgacggcgatgtggtggac
gatcttgccatcacgcggaaggaggatgatctctttacttctgtccttggtctcaagaaa
gaggaggtggtgcttgacctgtgctgtggtcaggggaggcactccctcgagctcgcacgc
aggggtttcaccagggtggaaggactcgacaggtcccactacctcatccagagggcgaag
gcccaggcggcgaaagaagggctgccggtgaagttcagagaaggggacgcacgaaaactg
ccctatcccccggatcagttcgacgtggtgatgatcctgggcaacagcttcggctacttc
gagagcagcaaggacgatcttcttgtcctaaaggaggtggcgcgtgtcctcaaaccgtgg
ggacggatactcctcgatctggccgatggtgagtatctacgagcacactacgttccccgc
tcatgggagtggatcgatgcaaagcactttgtctgcagggagcgggccctctcggctgat
cggcagaggctcatctcacgggaggtgatcgtccataccgagaagggggtggaggtggat
cagttctatgccgagaggctctacacacccgagctcatacgatctctcctcgaggaggcg
ggcttccaggaggtgtccttccacgggagtctcacccccgactcggcacggggacaggac
ctcgggatgatggagcggcgcatcctggtgagtgcgaggatacggaaggagtgggcacct
gtaaaatcgagaaagaagaatgtgtccactcaggtggcggtggtgatgggcgacccctcg
aagcccgatccgctcaagccgttcatggtgttcgacgacgatgatctctacaccatcgat
cggctcaaggctgcgctcaaagagtgtacaggctattccttcacctatctttcgcgccac
gagactctcatacaggatcttatgaggctcaaggggaaggtcgattacgtgttcaatctg
tgtgacgagggatttttcaacgatccgaggaaggagctgcacgtgccggcgctcctcgag
atgctcggcatcccctataccggcgcgacacctcaggggctcgccttctgctacgacaag
tcgctcgtacggggggtggcgaaggagatgggagtgcccgtgcctcgtgccttcttcata
gatcccacgtcgatcgtcttcgaggtaccgttcggttttcccatgatcgtcaagccgaac
ctcggagattccagtttcgggatcacgcagaagagcgtggtgtggtcgctcgatgagctt
tccgcctgcatctccgagatcagggatacgttcggctacgaaaagccggtgcttgtggag
gaattcctcacggggaaggatctgacggtggggatcatcgggaatccgacggacgactac
atggtgctccccatagtggaagaggactactcagcgctcccgccggagcttcctcggatc
tgcggatacgaggcgaaatggctccccgactctccctactggaaggccctccggtcgatt
cccgcagggcttcccgaggagacggagaagtccatcgtggagtggtgtgtccgtcttttc
gagcggctggagtgtcgggactacgcccggttcgactggagatgcgacgcggatgggaat
ccgtatcttctggaggtgaaccccaaccccggttggtgttgggacgggcacctcgcaaag
atggcacgcctcgcgggtatggagtatccccggatgctggaggccatcctgaaggcggcc
gagaagcgattggggatacggtcgtag
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