Spirochaeta thermophila DSM 6578: Spith_1886
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Entry
Spith_1886 CDS
T02016
Name
(GenBank) isocitrate dehydrogenase, NADP-dependent
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
stq
Spirochaeta thermophila DSM 6578
Pathway
stq00020
Citrate cycle (TCA cycle)
stq00480
Glutathione metabolism
stq01100
Metabolic pathways
stq01110
Biosynthesis of secondary metabolites
stq01120
Microbial metabolism in diverse environments
stq01200
Carbon metabolism
stq01210
2-Oxocarboxylic acid metabolism
stq01230
Biosynthesis of amino acids
Module
stq_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
stq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
Spith_1886
09106 Metabolism of other amino acids
00480 Glutathione metabolism
Spith_1886
Enzymes [BR:
stq01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
Spith_1886
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Motif
Pfam:
Iso_dh
DUF362
Motif
Other DBs
NCBI-ProteinID:
AEJ62144
UniProt:
G0GD69
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Position
complement(2111980..2113188)
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AA seq
402 aa
AA seq
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MGEKIRKEAGGLVVPDEPVIPFIQGDGTGPDIWRAAVRVFDAAVEKAYGGRRKVAWLEVF
AGERAYREKGTWLPDETLEAFKEYLVGIKGPLTTPVGGGFRSLNVTLRQMLDLYVCLRPV
KYYPGIPSPVRHPELVDMVVFRENTEDVYAGFELPSGDERTKRLIEFCRREFGWQIREDS
GIGVKPISPTGTKRLVRAAIRYALDHGRRSVTLVHKGNIMKYTEGAFRAWGYEVAKEEFG
DRVVTWEDVPDGVVPEGKVLVKDAIADAFLQQILTRPAEFDVIATMNLNGDYVSDALAAQ
VGGIGIAPGANINYDTGHAIFEATHGTAPKYAGKDMVNPSSVILSGKMMFEYLGWHEAAA
LIEKGLTGAIASRKVTYDFARLMEGAEQVSTSEFGNQIVAHM
NT seq
1209 nt
NT seq
+upstream
nt +downstream
nt
gtgggagagaagatacgaaaggaagctggaggactcgtcgtacctgacgagcccgtcatc
cccttcatccagggagatgggaccggtcccgacatatggcgtgcggcggttcgcgtcttc
gatgcagcggtggagaaggcctacggcggtaggcggaaggtggcgtggctggaggtgttt
gccggcgaacgggcctaccgggagaaggggacgtggctcccggacgagaccctcgaggcc
ttcaaggagtacctggtggggatcaaaggccccctcaccacgcccgtcggcggtggcttc
cggagcctcaacgtgacgctcaggcagatgctcgatctctacgtgtgtctgagaccggtg
aagtactatcccggcatcccctccccggtacgacacccggagctggtggacatggtggtc
ttccgggagaacaccgaggacgtctacgccggattcgagctcccctcgggggatgagcgt
acgaagcgtctcatcgagttctgcaggagggagttcgggtggcagatccgcgaggattcg
gggatcggggtcaagcccataagccccacggggacgaagcgtctcgtacgggccgcgatc
aggtacgccctcgaccacggaaggcgctccgtgaccctcgtgcacaaggggaacatcatg
aaatacaccgagggggccttcagggcgtggggttacgaggtggcgaaggaggagttcggc
gatcgggtggtcacctgggaggatgtccccgacggcgtcgtgccggaagggaaggtgctc
gtgaaggacgccatcgccgacgccttcctccagcagatcctcaccagacctgcggagttc
gacgtgatcgccaccatgaacctcaacggggactacgtctccgacgccctcgcagctcag
gtggggggtatcggtatcgctccgggggcgaacatcaactatgacacagggcatgcgatc
ttcgaggccacgcacggcaccgcacccaagtatgcggggaaggacatggtcaacccgagc
tccgtgatcctctcggggaagatgatgttcgagtacctcggctggcacgaggcggctgcg
ctcatcgaaaagggcctcaccggtgcgatcgcctcccgcaaggtcacctacgacttcgca
cgtctcatggaaggggccgaacaggtctccacgagtgagttcggtaaccagatcgtcgcc
cacatgtga
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