Streptomyces sp. 4F: ASR50_25225
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Entry
ASR50_25225 CDS
T04265
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
strf
Streptomyces sp. 4F
Pathway
strf00470
D-Amino acid metabolism
strf00550
Peptidoglycan biosynthesis
strf01100
Metabolic pathways
strf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strf00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
ASR50_25225
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ASR50_25225
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ASR50_25225
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
strf01011
]
ASR50_25225
Enzymes [BR:
strf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
ASR50_25225
Peptidoglycan biosynthesis and degradation proteins [BR:
strf01011
]
Precursor biosynthesis
Amino acid ligase
ASR50_25225
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GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATPgrasp_ST
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
ALV52386
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Position
5605630..5606787
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AA seq
385 aa
AA seq
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MSTENLPQSPDSPSRKPRVAVVFGGRSSEHGISVVTAGAVLKAIDRTRYDVLPIGITQDG
RWALTADEPERMAIAERRTPSVDQLAESTEGAVVLPVDPADREVVYSEPGSVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELSGIPYVGSGVLSSAVGQDKEYMKRVFTSFGLKVGPYLV
IRPREWARDEAAARKRIVDFAGEHGWPLFVKPARAGSSIGITKVDDLSGLDDAVAEARRH
DPKILVEAALRGREIECGVLEFEDGPRASLPAEIPPPDTHAYYDFEAKYIDSTPGMVPAP
LTDEETAEVRRLAVEAFDAASCEGLVRADFFLTEDGEFVINEINTMPGFTPISMYPQMWQ
ATGVSYQELVDLLIQAALRRSTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcaccgagaacctcccccagagccccgactcgccgtcgcgcaagccgcgtgtggcc
gtcgtgttcggcgggcgcagctccgagcacgggatctccgtggtcaccgccggcgccgtc
ctcaaggccatcgaccggaccaggtacgacgtcctgccgatcggcatcacccaggacggc
cggtgggcgctcaccgccgacgaaccggaacgcatggcgatcgccgagcgccgcacgccc
agcgtcgaccagctggccgagtccacggagggcgcggtggtgctccccgtcgaccccgcg
gaccgcgaagtcgtctacagcgagccgggatcggtgcccaaggcactcggtgaggtcgac
gtggtcttcccggtgctccacggcccctacggcgaggacggcaccctccagggcctgctc
gaactctccggcatcccctacgtgggctccggtgtgctctcctcggccgtcggccaggac
aaggagtacatgaagcgggtgttcacctccttcgggctcaaggtcggcccgtacctggtg
atccggccgcgcgagtgggcgcgggacgaggccgccgcccgcaagcggatcgtggacttc
gccggtgagcacggctggccgctgttcgtgaagcccgcccgggccggctcgtccatcggc
atcaccaaggtcgacgacctctccggcctggacgacgccgtcgccgaggcccggcgccac
gacccgaagatcctggtcgaggcggcgctgcgcgggcgcgagatcgagtgcggcgtgctg
gagttcgaggacggtccgcgtgcctcgctgcccgccgagatcccgccgccggacacgcac
gcgtactacgacttcgaggcgaagtacatcgactccacacccggcatggttcccgcgccg
ctgaccgacgaggagacggccgaggtgcgccggctcgcggtcgaggcgttcgacgcggcc
tcctgcgagggcctggtccgcgcggacttcttcctcacggaggacggcgagttcgtgatc
aacgagatcaacaccatgcccggcttcacgcccatctcgatgtacccgcagatgtggcag
gcgaccggtgtgagctaccaggagctcgtcgacctgctgatccaggcggcgctgcgccgg
tccaccggactgcgctga
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