Streptomyces sp. Mg1: M444_24550
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Entry
M444_24550 CDS
T03958
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
strm
Streptomyces sp. Mg1
Pathway
strm00470
D-Amino acid metabolism
strm00550
Peptidoglycan biosynthesis
strm01100
Metabolic pathways
strm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
strm00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
M444_24550
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M444_24550
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M444_24550
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
strm01011
]
M444_24550
Enzymes [BR:
strm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
M444_24550
Peptidoglycan biosynthesis and degradation proteins [BR:
strm01011
]
Precursor biosynthesis
Amino acid ligase
M444_24550
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
AKL68061
UniProt:
B4V5A3
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All DBs
Position
1:5608514..5609671
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AA seq
385 aa
AA seq
DB search
MSSENLPQTPEQQGRKPRVAVVFGGRSSEHAISVVTAGAVLRSIDRSKYEVLPIGITTDG
RWALTADEPSRMAIADRKLPSVDDLADSEDGAVVLSVDPANREVVYTEPGAVPKALGEVD
VVFPVLHGPYGEDGTLQGLLELAGIPYVGSGVLASAVGQDKDYMKRVFTSFGLNVGPYLT
VRPREWTRDADAARGRILDFAEEHGWPLFIKPARAGSSIGITKVDDVSGLDEAVREAQRH
DPKIIVEARLRGREIECGVLEFEDGPRASVPAEIPPVSSHDFYDFEAKYIDSASGIVPAP
LTPEQTAEVRRLAVEAFEAASCEGLVRADFFLTEDGTFVINEINTMPGFTPISMYPRMWQ
ESGVEYQELVDLLIQAALRRPTGLR
NT seq
1158 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagacccctgagcagcagggccgcaagccccgcgtggcc
gtcgtgttcggcggccgcagctcggaacacgccatctcggtcgtcaccgcgggcgccgtg
ctgcgctccatcgaccggtccaagtacgaggtgctgcccatcggcatcaccaccgacggc
cggtgggcgctgaccgccgacgagccgtcccggatggccatcgccgaccggaagctcccc
agcgtcgacgacctcgccgactccgaggacggcgccgtcgtgctctcggtggaccccgcc
aaccgcgaggtcgtctacaccgagccgggcgccgtccccaaggccctgggcgaggtcgac
gtcgtcttcccggtgctgcacggcccgtacggcgaggacggcaccctccaggggctgctg
gagctcgccgggatcccgtacgtcggctccggcgtcctcgcctcggccgtcggccaggac
aaggactacatgaagcgggtgttcacgtccttcggactgaacgtcggcccgtacctcacc
gtccgcccccgcgagtggacgcgcgacgcggacgccgcccgcggccggatcctggacttc
gccgaagagcacggctggccgctgttcatcaagcccgcccgggccggctcctcgatcggc
atcaccaaggtcgacgacgtctccggcctggacgaagcggtccgcgaggcccagcgccac
gacccgaagatcatcgtcgaggcgcggctgcgcggccgcgagatcgagtgcggcgtgctg
gaattcgaggacgggccgcgcgcgagcgtccccgccgagatcccgccggtctccagccat
gacttctacgacttcgaggcgaagtacatcgactccgcctccggaatcgtgcccgccccg
ctcaccccggagcagaccgccgaggtgcggcggctcgcggtcgaggccttcgaggccgcg
tcctgcgagggcctggtgcgcgccgacttcttcctcaccgaggacggcaccttcgtcatc
aacgagatcaacaccatgccgggcttcacccccatctccatgtacccgcgcatgtggcag
gagtccggggtcgagtaccaggaactggtcgacctcctgatccaggccgccctgcgccgc
cccacggggctgcgctag
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