Streptomyces qaidamensis: A4E84_27060
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Entry
A4E84_27060 CDS
T04777
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
stsi
Streptomyces qaidamensis
Pathway
stsi00020
Citrate cycle (TCA cycle)
stsi00630
Glyoxylate and dicarboxylate metabolism
stsi00785
Lipoic acid metabolism
stsi01100
Metabolic pathways
stsi01110
Biosynthesis of secondary metabolites
stsi01120
Microbial metabolism in diverse environments
stsi01200
Carbon metabolism
stsi01210
2-Oxocarboxylic acid metabolism
Module
stsi_M00009
Citrate cycle (TCA cycle, Krebs cycle)
stsi_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
stsi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
A4E84_27060 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
A4E84_27060 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
A4E84_27060 (kgd)
Enzymes [BR:
stsi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
A4E84_27060 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
A4E84_27060 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
A4E84_27060 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
A4E84_27060 (kgd)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
OxoGdeHyase_C
Transket_pyr
2-oxogl_dehyd_N
Motif
Other DBs
NCBI-ProteinID:
AMW12826
UniProt:
A0A143C5Q8
LinkDB
All DBs
Position
complement(6061132..6064962)
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AA seq
1276 aa
AA seq
DB search
MSPQSPSNSSISTDTDQAGKNPAASFGANEWLVDEIYQQYLQDPNSVDRAWWDFFADYKP
GAAAASAPAGTAAAGAAGTTTAQPAAPAAPTQAPAPAAEKPAAAPAPAPAPAPAKPAAQA
PAQAPAPAQAAPAAKPAAKPAAAPKKAEPAAEAPSGPEQVVLRGPAAAVAKNMNASLEVP
TATSVRAVPVKLLFDNRIVINNHLKRARGGKISFTHLIGYAMVQAIKAMPSMNYSFAEKD
GKPTLVKPEHVNFGLAIDLVKPNGDRQLVVAGIKKAETLNFFEFWQAYEDIVRRARDGKL
GMDDFTGVTVSLTNPGGLGTVHSVPRLMPGQSVIMGVGSMDYPAEFQGTSQDTLNKLGIS
KVMTLTSTYDHRVIQGAASGEFLRIVANLLLGENGFYDDVFEALRIPYEPVRWLKDIDAS
HDDDVTKAARVFELIHSYRVRGHVMADTDPLEYQQRKHPDLDITEHGLTLWDLEREFAVG
GFAGKSLMKLRDILGVLRDSYCRTTGVEFMHIQDPKQRKWIQDRIERSHTKPEREEQLRI
LRRLNAAEAFETFLQTKYVGQKRFSLEGGESVIPLLDAVLDSAAESRLDEVVVGMAHRGR
LNVLANIVGKSYAQIFREFEGNLDPKSMHGSGDVKYHLGAEGTFTGLDGEQIKVSLVANP
SHLEAVDPVLEGVSRAKQDIINKGGTDFTVLPVAIHGDAAFAGQGVVAETLNMSQLRGYR
TGGTVHIVINNQVGFTAAPESSRSSMYATDVARMIEAPIFHVNGDDPEAVVRVARLAFEF
RQAFNKDVVIDLICYRRRGHNESDNPAFTQPLMYDLIDKKRSVRKLYTESLIGRGDITLE
EAEQALQDYQGQLEKVFTEVREATSQPGTVESTDPQAEFPVAVNTAVTTEIVKRIAESQV
NIPDNITVHPRLLPQLQRRASMVEDGTIDWGMGETLAIGSLLLEGVPVRLAGQDSQRGTF
GQRHAVIIDRSTGEEYTPLQYLSEDQARLNVYNSLLSEYAAMGFEYGYSLARPEALVMWE
AQFGDFVNGAQTVVDEFISSAEQKWAQTSGVVLLLPHGYEGQGPDHSSARPERFLQMCAQ
NNMTVAMPTSPSNYFHLLRWQVHNPHHKPLVVFTPKSMLRLKAAAAKAEEFTTGQFQPVI
GDSSVDAAAVRKVVFCAGKVYYDLEAERQKRGATDTAIIRIERLYPLPGAELQAEIKKYP
NAEKYLWAQEEPANQGAWPFIALNLIDHLDLAVGADVPHGERLRRISRPHGSSPAVGSAK
RHQAEQEQLVREVFEA
NT seq
3831 nt
NT seq
+upstream
nt +downstream
nt
gtgtcgccacagtcccccagtaactcgagcatctcgaccgacaccgaccaagcggggaag
aaccctgccgcgtcgttcggtgccaacgagtggctcgtcgacgagatctatcagcagtac
ctccaggacccgaattcggtagaccgagcctggtgggacttcttcgccgactacaagccg
ggggcggccgccgcctcggctccggcgggtaccgcggccgcgggggccgcggggaccacc
accgctcagccggccgctccggccgctcccacccaggcccccgccccggcggccgagaag
cccgccgccgcgccggctcccgccccggctccggccccggcgaagcccgccgcgcaggcc
ccggcccaggcccccgccccggcgcaggccgccccggccgcgaagccggccgccaagccg
gccgcggccccgaagaaggccgagcccgccgccgaggccccctcgggccccgaacaggtc
gtgctgcgcggccccgccgccgcggtcgcgaagaacatgaacgcctcgctggaggtgccc
acggccacgtccgtgcgcgcggtcccggtgaagctgctgttcgacaaccgcatcgtcatc
aacaaccacctgaagcgcgcccggggcgggaagatctccttcacgcacctgatcggctac
gcgatggtgcaggccatcaaggccatgccgtcgatgaactactccttcgcggagaaggac
ggcaagccgaccctggtcaagccggagcacgtcaacttcggcctcgccatcgacctggtc
aagcccaacggcgaccgccagctcgtggtcgcgggcatcaagaaggccgagacgctgaac
ttcttcgagttctggcaggcctacgaggacatcgtccgccgcgcccgcgacggcaagctg
ggcatggacgacttcaccggtgtgacggtctccctgaccaaccccggcggcctcggcacc
gtccactccgtgccgcgcctgatgcccggccagtcggtgatcatgggcgtcggctccatg
gactacccggcggagttccagggcacctcccaggacaccctgaacaagctcggcatctcg
aaggtcatgacgctcacgtcgacctacgaccaccgggtcatccagggcgccgcctccggc
gagttcctgcggatcgtcgcgaacctgctgctcggtgagaacggcttctacgacgacgtc
ttcgaggcgctgcgcatcccctacgagccggtccgctggctcaaggacatcgacgcgtcg
cacgacgacgacgtcacgaaggccgcccgcgtcttcgagctgatccactcctaccgggtc
cgcggccacgtcatggccgacaccgacccgctggagtaccagcagcgcaagcaccccgac
ctggacatcaccgagcacggcctcacgctctgggacctggagcgcgagttcgccgtcggc
gggttcgccggcaagtccctgatgaagctgcgcgacatcctcggcgtgctgcgcgactcg
tactgccgcaccaccggcgtcgagttcatgcacatccaggacccgaagcagcgcaagtgg
atccaggaccgcatcgagcgctcgcacaccaagccggagcgcgaggagcagctgcgcatc
ctgcgccggctgaacgccgccgaggccttcgagaccttcctgcagacgaagtacgtcggc
cagaagcgcttctccctggagggcggcgagtccgtcatcccgctgctggacgccgtgctg
gactcggccgccgagtcccgcctggacgaggtcgtcgtcggcatggcccaccgcggccgg
ctgaacgtcctcgccaacatcgtcggcaagtcgtacgcgcagatcttccgcgagttcgag
ggcaacctcgacccgaagtcgatgcacggctccggtgacgtgaagtaccacctgggcgcc
gagggcaccttcaccggtctcgacggcgagcagatcaaggtctccctggtcgcgaacccc
tcgcacctggaggcggtggacccggtcctggagggcgtctcgcgcgccaagcaggacatc
atcaacaagggcggcacggacttcaccgtcctgccggtggcgatccacggcgacgcggcc
ttcgcgggccagggcgtggtggccgagaccctgaacatgtcgcagctgcgcggctaccgc
accggcggcacggtccacatcgtcatcaacaaccaggtcggcttcaccgcggcccccgag
tcctcgcgatcctccatgtacgcgacggacgtggcccgcatgatcgaggccccgatcttc
cacgtgaacggcgacgacccggaggccgtggtccgcgtcgcgcggctcgccttcgagttc
cgccaggcgttcaacaaggacgtggtgatcgacctcatctgctaccgccgccgcggtcac
aacgagtcggacaacccggccttcacccagccgctgatgtacgacctgatcgacaagaag
cgctcggtgcgcaagctctacaccgagtccctcatcggtcgcggcgacatcaccctggaa
gaggccgagcaggcgctgcaggactaccagggccagctggagaaggtcttcacggaggtc
cgtgaggccacctcccagccgggcacggtcgagtccacggacccgcaggccgagttcccg
gtcgccgtgaacaccgcggtgaccacggagatcgtcaagcggatcgccgagtcccaggtc
aacatccccgacaacatcaccgtccacccgcgtctgctgccgcagctgcagcgccgggcg
tcgatggtcgaggacggcacgatcgactggggcatgggcgagaccctcgcgatcggctcc
ctcctgctggagggcgtcccggtccgcctggcgggccaggactcgcagcgcggtacgttc
ggccagcgccacgcggtcatcatcgaccgcagcacgggcgaggagtacacgccgctgcag
tacctctccgaggaccaggcgcggctcaacgtctacaactccctgctctccgagtacgcg
gcgatgggcttcgagtacggctactcgctggcccgccccgaggcgctcgtgatgtgggag
gcgcagttcggcgacttcgtcaacggcgcgcagacggtcgtggacgagttcatctcgtcg
gccgagcagaagtgggcccagacctccggtgtcgtcctgctcctgccgcacggctacgag
gggcagggcccggaccactcctcggcccgcccggagcgcttcctccagatgtgcgcccag
aacaacatgacggtcgccatgccgacgtcgccgtcgaactacttccacctcctgcggtgg
caggtgcacaacccgcaccacaagccgctggtggtcttcacgccgaagtcgatgctgcgc
ctgaaggcggcggcggcgaaggcggaggagttcacgaccgggcagttccagccggtcatc
ggtgactcctcggtcgacgcggccgcggtcaggaaggtcgtcttctgcgccggcaaggtc
tactacgacctggaggccgagcgtcagaagcgcggcgccacggacacggcgatcatccgc
atcgagcgcctgtacccgctgccgggtgccgagctccaggcggagatcaagaagtacccg
aacgccgagaagtacctgtgggcccaggaggagccggcgaaccagggtgcctggccgttc
atcgcgctcaacctgatcgaccacctggacctcgcggtcggcgcggacgttccgcacggt
gagcggctgcggcgcatctcgcgcccgcacggctcgtccccggcggtgggttccgcgaag
cgccaccaggccgagcaggagcaactggtgcgtgaggtgttcgaggcgtaa
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