Streptomyces venezuelae: SVEN_5252
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Entry
SVEN_5252 CDS
T02274
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
sve
Streptomyces venezuelae
Pathway
sve00470
D-Amino acid metabolism
sve00550
Peptidoglycan biosynthesis
sve01100
Metabolic pathways
sve01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sve00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SVEN_5252
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SVEN_5252
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SVEN_5252
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
sve01011
]
SVEN_5252
Enzymes [BR:
sve01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SVEN_5252
Peptidoglycan biosynthesis and degradation proteins [BR:
sve01011
]
Precursor biosynthesis
Amino acid ligase
SVEN_5252
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
ATP-grasp_4
ATPgrasp_ST
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
CCA58538
UniProt:
F2R5D4
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All DBs
Position
5678369..5679508
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AA seq
379 aa
AA seq
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MSENTQSPRKPRVAVVFGGRSSEHAISVVTAGAVLSAIDRDKYDVLPIGITTDGRWALTA
DAPERMAIADRALPNVADLAESETGGVVLSVDPADRQVVLTEPGAVPKALGEVDVVFPML
HGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFVSFGLPVGPYEVIRPREW
EQNPAAARKKIVEFAAEHGWPLFVKPARGGSSMGITKVDDLSGLDEAIEEARRHDPKILV
ESLLRGREIECGVLEFEDGPRASVPAEIPPVTNHDFYDFEAKYIDSASGIVPAPIGDEAT
AEIQRLAVAAYEAVSCEGLVRADFFLTEDGDFVINEINTMPGFTPISMYPRMWQESGVSY
PELVDRLIQAALTRSTGLR
NT seq
1140 nt
NT seq
+upstream
nt +downstream
nt
atgagcgagaacacccagagcccccgcaagccgcgcgtggccgtcgtcttcggcggacgc
agctccgagcacgccatctccgtcgtcacggcgggcgccgtcctgagcgccatcgaccgg
gacaagtacgacgtgctgcccatcggcatcacgacggacgggcgctgggcgctcaccgcc
gacgcccccgagcgcatggccatcgccgaccgcgccctgccgaacgtcgccgacctggcc
gagtccgagaccggcggcgtcgtcctctccgtcgaccccgccgaccgccaggtcgtcctc
accgagcccggtgccgtgcccaaggccctcggcgaggtcgacgtggtcttcccgatgctc
cacggcccctacggcgaggacggcaccctccagggcctcctggagctctccggcgtcccc
tacgtcggcgcgggcgtcctcgcctccgccgtcggccaggacaaggagtacatgaagcgg
gtcttcgtctccttcggcctccccgtcggaccgtacgaggtcatccggccccgcgagtgg
gagcagaacccggcggccgcccgcaagaagatcgtcgagttcgccgccgagcacggctgg
ccgctcttcgtgaagccggcccgcggcggctcctccatgggcatcaccaaggtcgacgac
ctctccggcctcgacgaggccatcgaggaggcccggcgccacgaccccaagatcctcgtc
gagtcgctgctgcgcggccgggagatcgagtgcggcgtcctggagttcgaggacggcccg
cgcgccagcgtgccggccgagatcccgccggtcacgaaccacgacttctacgacttcgag
gccaagtacatcgactcggcctccggcatcgtgcccgcgccgatcggcgacgaggccacc
gccgagatccagcgcctggccgtcgccgcctacgaggcggtgtcctgcgagggcctggtg
cgcgccgacttcttcctcaccgaggacggcgacttcgtcatcaacgagatcaacaccatg
ccgggcttcacgccgatctcgatgtatccgcgcatgtggcaggagagcggcgtgagctac
cccgagctcgtcgaccggctcatccaggccgcgctgacccgctccacgggcctgcgctga
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