Thermobispora bispora: Tbis_2809
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Entry
Tbis_2809 CDS
T01236
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
tbi
Thermobispora bispora
Pathway
tbi00290
Valine, leucine and isoleucine biosynthesis
tbi00620
Pyruvate metabolism
tbi01100
Metabolic pathways
tbi01110
Biosynthesis of secondary metabolites
tbi01210
2-Oxocarboxylic acid metabolism
tbi01230
Biosynthesis of amino acids
Module
tbi_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
tbi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Tbis_2809
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Tbis_2809
Enzymes [BR:
tbi01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Tbis_2809
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
URO-D
Motif
Other DBs
NCBI-ProteinID:
ADG89508
UniProt:
D6Y692
LinkDB
All DBs
Position
complement(3285497..3287077)
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AA seq
526 aa
AA seq
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MADDRFHVYDTTLRDGAQQEGLNLTVADKLAIARYLDRLGVGFIEGGWPGANPKDTEFFR
RARTELDLKHAQLAAFGSTRRPGMKAADDPLVAALRESEAPVVTLVAKSHDRHVELALRT
TLEENLEMIRDTVSHLRAEGRRVFLDAEHFFDGYRSNPAYALEVIRTAAEAGADVVALCD
TNGGMLPDELADVVHEAVTATGARIGIHCHDDSGCAVANTLAAVKAGATHVQGCANGYGE
RSGNANLFTVVANLQLKRGYDLVPPESLRELTHIAHAISEITNVTPNSHQPYVGVSAFAH
KAGLHASAIKVDPMLYQHIDPALVGNDMRMLVSDMAGRASVELKGRALGYELTREQSTAL
VERVKELEAQGYTFEAADASFELLLRDTVGELRPRYFTVESWRVIVERRPDGEVVSEATV
KLNAKGERIIATGEGNGPVNALDKAVRVALERLYPELAAVELIDYKVRILEGSHGTGAVT
RVLITSSDTDGEWSTVGVDENIIEASWQALEQAVTYGLLRAGRTAP
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atggctgacgacaggttccacgtgtatgacacgacgctgcgcgacggcgctcagcaagaa
gggctcaatctgaccgtcgccgacaagctcgccatcgcccgctacctggaccggctcggc
gtcggcttcatcgagggcggctggccgggcgccaaccccaaggacaccgagttcttccgg
cgtgcccgcaccgagctcgacctgaagcacgcgcagctcgccgcgttcggctcgacccgc
cggccggggatgaaggccgcggacgacccgctggtggccgcgctgcgcgagtccgaggcg
ccggtggtgacgctggtcgcgaagagccacgaccggcacgtggagctcgccctccgcacc
acgctcgaggagaacctcgagatgatccgggacaccgtctcccacctgcgcgccgagggc
cggcgggtcttcctcgacgccgagcacttcttcgacggctaccggtccaatcccgcgtac
gccctggaggtgatccgcaccgcggccgaggcgggcgccgacgtggtcgccctctgcgac
accaacggcggcatgctccccgacgagctcgccgatgtggtgcacgaggccgtcaccgcc
accggcgcccggatcggcatccactgccacgacgacagcgggtgcgcggtggcgaacacc
ctcgccgcggtcaaggccggggccacccacgtgcagggctgcgccaacgggtacggcgag
cgctccggcaacgccaacctcttcacggtcgtggccaacctgcagctcaagcgcggctac
gacctcgtgccgccggagtcgctccgcgagctcacccacatcgcccacgcgatcagtgag
atcaccaacgtcacccccaactcccaccagccgtacgtcggggtgtccgccttcgcgcac
aaggccggcctgcacgcgtcggcgatcaaggtggacccgatgctctaccagcacatcgac
cccgccctggtcggcaacgacatgcggatgctcgtctcggacatggccggccgggcctcg
gtcgagctgaagggccgcgccctcggctacgagctcacccgcgagcagtccactgcgctc
gtggaacgtgtgaaggagctggaggcccaggggtacaccttcgaggccgcggacgcgtcg
ttcgagctgctgctccgggacaccgtcggtgagctgcggccccgctacttcacggtcgag
tcgtggcgggtgatcgtggagcgccgcccggacggcgaggtggtgagcgaggccaccgtg
aagctgaacgccaagggcgagcggatcatcgcgaccggcgagggcaacggcccggtgaac
gcgctcgacaaggcggtccgggtcgcgctcgagcggctctaccccgagctcgccgcggtc
gagctgatcgactacaaggtccggatcctcgagggcagccacggcacgggcgcggtgacc
cgcgtgctgatcacgtcgagcgacaccgacggcgagtggtccacggtcggcgtcgacgag
aacatcatcgaggcgtcctggcaggccctcgagcaggcggtcacctacggcctgctccgc
gccgggcgcaccgcaccctga
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