Thermomonospora curvata: Tcur_4976
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Entry
Tcur_4976 CDS
T01127
Name
(GenBank) D-alanine/D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tcu
Thermomonospora curvata
Pathway
tcu00470
D-Amino acid metabolism
tcu00550
Peptidoglycan biosynthesis
tcu01100
Metabolic pathways
tcu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tcu00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
Tcur_4976
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tcur_4976
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tcur_4976
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tcu01011
]
Tcur_4976
Enzymes [BR:
tcu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
Tcur_4976
Peptidoglycan biosynthesis and degradation proteins [BR:
tcu01011
]
Precursor biosynthesis
Amino acid ligase
Tcur_4976
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp_4
CPSase_L_D2
ATP-grasp_3
ATP-grasp
TTL
ATPgrasp_YheCD
Motif
Other DBs
NCBI-ProteinID:
ACZ00491
UniProt:
D1A961
LinkDB
All DBs
Position
5630635..5631594
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AA seq
319 aa
AA seq
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MADLNVPELGHVIVLAGGLSYEREVSLRSGRRVADALRALDVDAQVHDADATLLQTLQQA
PPDAVFPVLHGSMGEDGAIRDVLELVGVPYVGARPDACRVAWDKPTAKSVVRAAGLATPP
SVTLPKEVFHDLGAAAVLECVVRRLGLPLFVKPARGGSALGASVVREAGDLPAAMVGCFA
YGDAALIERHIEGTEVAVSVIERDGEPVALPAVEIVPAGELYDYTARYDAGDTEFVTPAR
LPEEVARRAAEAAVTAHRALGLRDLSRTDLIVDEAGQVHFLEVNVAPGMTETSLFPRAVA
AAGLNLGRILHDLIVARLR
NT seq
960 nt
NT seq
+upstream
nt +downstream
nt
ttggccgatctgaacgtccccgaactcggccacgtcatcgtcctggcgggcgggctgtcg
tatgagcgggaggtgtcgctgcgctcgggccgccgggtcgccgacgcgctgcgcgccctc
gacgtggacgcccaggtccacgacgccgacgccaccttgctgcagacgctgcagcaggct
cccccggacgccgtcttccccgtgctgcacggcagcatgggcgaggacggcgccatccgg
gacgtgctggagctggtcggcgtcccttacgtcggcgcccgcccggacgcctgccgggtc
gcctgggacaagcccaccgccaagtcggtggtgcgcgccgccgggctggccaccccgccc
tcggtgacgctgcccaaggaggtcttccacgacctcggcgccgccgccgtgctggagtgc
gtggtgcgccggctgggcctgccgctgttcgtcaagcccgcccgcggcggctccgcgctc
ggcgcctcggtcgtccgggaggccggcgacctgcccgccgcgatggtcggctgcttcgcc
tacggggacgccgccctcatcgaacgccacatcgagggcaccgaggtcgcggtgagcgtc
atcgagcgcgacggcgagccggtcgcgctgcccgccgtggagatcgtcccggccggggag
ctgtacgactacaccgcccgctacgacgccggcgacaccgagttcgtcacccccgcccgg
ctgcctgaggaggtcgcccgccgggccgccgaggccgccgtcaccgcccaccgcgccctg
ggcctgcgcgacctgtcccgcaccgacctcatcgtggacgaggccgggcaggtccacttc
ctggaggtcaacgtggcccccggaatgaccgagaccagcctcttcccccgcgccgtggcc
gctgccggcctcaacctcggccgcatcctgcacgacctgatcgtcgcccgcctccgctga
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