Thermobifida fusca: Tfu_0633
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Entry
Tfu_0633 CDS
T00265
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
tfu
Thermobifida fusca
Pathway
tfu00470
D-Amino acid metabolism
tfu00550
Peptidoglycan biosynthesis
tfu01100
Metabolic pathways
tfu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
tfu00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
Tfu_0633
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Tfu_0633
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Tfu_0633
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tfu01011
]
Tfu_0633
Enzymes [BR:
tfu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
Tfu_0633
Peptidoglycan biosynthesis and degradation proteins [BR:
tfu01011
]
Precursor biosynthesis
Amino acid ligase
Tfu_0633
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
ATP-grasp_4
CPSase_L_D2
GARS_A
Motif
Other DBs
NCBI-ProteinID:
AAZ54671
UniProt:
Q47S96
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All DBs
Position
735585..736700
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AA seq
371 aa
AA seq
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MGEQRKIRVAVIFGGRSSEHEISCVTAGSVMSAIDTDRYDILPIGITRDGDWRLVTADPS
ELAIVDGKLPAVPDSGARLALALDTPGAFLEVAPDSLPRLVGQVDVVLPLLHGPFGEDGT
IQGLLELAGVRYVGAGVFASAASMDKVFMKALLTAQGLKTGPYLAVSDRAWTRHRKRVLD
NIAALGGVVFVKPARAGSSIGISRVPDATDTAAVTEAIEAARAHDPKVIVEAGIQGREIE
CGVLESLDGGEPDVSLPAEIHVAEGYDFYDFEAKYLSNSGLSIPADLPDEVTQRVRKLAA
EAFDALGCEGLARVDFFYGDDGEIYINEINTMPGFTPASAFPQMWAASGLDYPALVDRLI
RTALVRRTGLR
NT seq
1116 nt
NT seq
+upstream
nt +downstream
nt
atgggtgagcagcgaaagatccgggttgccgtcatcttcggcggacgcagttccgaacac
gagatctcctgcgtgaccgcgggaagcgtgatgtccgccatcgataccgaccgctacgac
atcctgcccatcggaatcacgcgggacggtgactggaggctggtcaccgcggatcccagc
gagttggcaatcgttgacggcaagcttccggccgtgcccgacagcggcgcgcgactggcc
ctggccctcgacacgcccggcgctttcctggaggtcgccccggacagcctgccgcggctc
gtcggccaggtcgacgtggtgctgccgctgctgcacggccccttcggggaggacggcacc
atccaagggctgctggaactcgccggagtccgctacgtgggtgccggagtgttcgccagc
gccgcttccatggacaaggtcttcatgaaggcgctgctcaccgcgcagggcctgaagacc
ggcccgtatcttgcggtcagtgaccgggcgtggacccgccaccgcaaacgcgtgctggac
aacatcgccgcgctcggcggggtggtgttcgtcaagcctgcccgcgccgggtccagcatc
ggcatcagccgggtgcccgacgccaccgacaccgccgcggtcaccgaagccatcgaggcc
gcacgcgcccacgacccgaaggtcatcgtggaagccgggatccagggccgggagatcgaa
tgcggcgtgttggagagcctggacggcggggagcctgacgtgtcgctgcccgcggaaatc
cacgtggccgaggggtacgacttctacgacttcgaggccaagtacctctccaacagcggt
ctgagcatccccgcggacctgcctgacgaggtgacccagcgggtgcggaaactcgccgcg
gaagcgttcgacgcgctgggctgcgaaggactggcccgcgtggacttcttctacggcgac
gacggggagatctacatcaacgagatcaacaccatgccgggcttcacgccggcttcggcg
ttcccgcagatgtgggcggcgagcggtctggactacccggcgctggtggaccggctgatc
cgcaccgcgctcgtgcgtcgcaccggcctgcgttag
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