Thermus sp. CCB_US3_UF1: TCCBUS3UF1_7140
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Entry
TCCBUS3UF1_7140 CDS
T01866
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
thc
Thermus sp. CCB_US3_UF1
Pathway
thc00470
D-Amino acid metabolism
thc00550
Peptidoglycan biosynthesis
thc01100
Metabolic pathways
thc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thc00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
TCCBUS3UF1_7140
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
TCCBUS3UF1_7140
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
TCCBUS3UF1_7140
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
thc01011
]
TCCBUS3UF1_7140
Enzymes [BR:
thc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
TCCBUS3UF1_7140
Peptidoglycan biosynthesis and degradation proteins [BR:
thc01011
]
Precursor biosynthesis
Amino acid ligase
TCCBUS3UF1_7140
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
ATP-grasp_3
TPP_enzyme_C
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
AEV15762
UniProt:
G8NAZ3
LinkDB
All DBs
Position
697428..698396
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AA seq
322 aa
AA seq
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MALPRVLLIAGGRSPEHEVSLLSARGVLEHMPFPTELAVIAKDGGWLLGERALGALGAGQ
ALQGEHPFPPDLDWNRYDVVFPLLHGRWGEDGTLQGFLELLGRPYVGAGVAASALCMDKD
LSKRVLAQAGVPVVPWVALYPGERPFLPFEPPYFVKPANTGSSVGIRRVESHAGLEEALE
EAFRHDGKAVVEKALLGVRELEVGVLGNVFAEASPVGEVRYQAPFYDYETKYTPGRAELL
IPAPLDPGTQETIQEMALKAYRLLGIRGMARVDFFLVEGEVYLNEINTIPGFTPTSMYPK
LFQAAGVSYPELLKRLVELALA
NT seq
969 nt
NT seq
+upstream
nt +downstream
nt
atggcgcttcctagggtgctcctcatcgccgggggacgaagcccggagcacgaggtttcc
ctcctttccgcccggggcgttttggaacacatgccctttcccacggagcttgcggtcatc
gccaaggacgggggctggctcttgggggaaagggcccttggggccctaggggcaggccag
gcccttcagggggaacacccctttcctcccgacctggactggaaccgctacgatgtggtc
tttcccctcctgcacggccgctggggcgaggacgggaccctgcagggctttctggagctc
ctgggccggccctacgtgggggcgggggtggcggccagcgccctttgcatggacaaggac
ctctccaagcgggtcctggcccaggccggggtgcccgtggtgccctgggtggccctatac
cctggggagaggccctttctcccctttgaacctccctacttcgtcaagcccgccaacacc
ggttccagcgtgggcatccggcgcgtggagagccatgccgggctggaggaggccctggag
gaggctttccgccacgacggcaaagcggtggtggagaaggccctccttggggtgcgggag
ctggaggtgggggttttgggcaacgtcttcgccgaggccagccccgtgggggaggtgcgc
taccaggcccccttctacgattacgagaccaagtacacccccgggagggccgagctcctg
atccccgcccccctggacccgggtacccaggagaccatccaggagatggccctgaaggcc
taccgcctcctgggcatccgcgggatggcccgggtggacttcttcctggtggaaggggaa
gtttacctcaacgagatcaacaccattcccggcttcacccccaccagcatgtaccccaag
ctcttccaggctgccggggtttcctaccccgagctcctcaagcggctggtggagttggcc
ctggcctag
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