Thermaerobacter sp. PB12/4term: DYI95_010865
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Entry
DYI95_010865 CDS
T06418
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
thep
Thermaerobacter sp. PB12/4term
Pathway
thep00470
D-Amino acid metabolism
thep00550
Peptidoglycan biosynthesis
thep01100
Metabolic pathways
thep01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
thep00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
DYI95_010865
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DYI95_010865
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DYI95_010865
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
thep01011
]
DYI95_010865
Enzymes [BR:
thep01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
DYI95_010865
Peptidoglycan biosynthesis and degradation proteins [BR:
thep01011
]
Precursor biosynthesis
Amino acid ligase
DYI95_010865
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
ATP-grasp
CPSase_L_D2
Motif
Other DBs
NCBI-ProteinID:
QIA27945
UniProt:
A0A8T8DA72
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Position
complement(2606173..2607453)
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AA seq
426 aa
AA seq
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MKEHAAAPQAGGPTPAPRREDGGRATGPAAAGPGAAPGPRRLRVGILFGGRSGEHEVSLM
SARSVFEAMDRRRFEPVPIGITREGLWILPHDAPGLLKAGRGVEPGDGIPLAVVPGPQGA
RLLLLEAGGGAGSSAAGGAGEDGAPVQGRRLEPLDVVFPVLHGTFGEDGTVQGLLELAGI
PYVGAGVMASAVGMDKAVMKELFRARGLPVVPFLVVTAARWRREPAAVLDAIEQSLGYPC
FTKPANLGSSVGITRCPDRATLEAGLAEAFAYDRKVVVERGVDARELEISVLGNDDPVAS
VPGEIRPRDAFYTYQAKYTEGGSDLIVPAQLPPRVVEEMQRLAIAAFQAIDAAGLARVDF
FLERATGRLLVNEINTIPGFTALSMYPKLWEAAGLPYRDQITRLIELALERHGERARLRT
TYGDGA
NT seq
1281 nt
NT seq
+upstream
nt +downstream
nt
atgaaagaacacgcggcggccccccaggccggcgggcccacgccggccccgcgccgcgag
gacggcggaagggccaccggaccggccgcggcgggcccgggggccgcgcccgggccgcgc
cggctgcgggtgggcatcctgttcggcggccggtcgggggagcacgaggtctccctgatg
tcggcccggtccgtcttcgaggccatggatcggcggcggttcgagcccgtgcccatcggg
atcacccgggaaggcctctggatcctgccccacgatgcgccgggcctgctgaaggcaggg
cggggggtcgaacccggcgacggcatccccctggccgtggtgcccggcccgcagggtgcc
cgcctgctgctgctggaggccggcggcggagccggttcgtccgcagccggaggggccggg
gaggacggggcgcccgtgcaggggcgccggctcgagccgctggacgtggtcttccccgtg
ctgcacggcaccttcggtgaagacggcaccgtccaggggcttctggagctggccggcatc
ccctacgtgggggccggcgtcatggcgtcggccgtcggcatggacaaggccgtcatgaag
gagcttttccgggctcggggcctgcccgtggtgcccttcctggtggtgacggccgcccgc
tggcgccgggagccggcggcggtgctggacgccatcgagcagtccctgggctacccctgc
ttcaccaagcccgccaacctggggtccagcgtgggcatcacccgctgtcccgaccgggcc
accctggaggccggcctggccgaggccttcgcctacgaccgcaaggtggtggtcgagcgc
ggcgtcgacgcccgggaactggagatcagcgtgctgggcaacgacgaccccgtggcctcg
gtgccgggcgagatccggccccgggacgcgttctacacctaccaggccaagtacaccgag
ggcggatcggacctgatcgtgccggcccagcttcctccccgggtggtggaggagatgcag
cggctggccatcgcggccttccaggccatcgacgccgccggcctggcccgggtggacttc
ttcctcgagcgggccaccggccggctgctggtcaacgagatcaacaccatccccggcttc
accgccctgagcatgtaccccaagctgtgggaggcggcgggcctgccctatcgcgaccag
atcacccgcctcatcgaactggcgctggagcggcatggtgaacgggcccgcctccggaca
acctatggagacggggcatga
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