KEGG   Trichechus manatus latirostris (Florida manatee): 101345902
Entry
101345902         CDS       T05135                                 
Name
(RefSeq) serine/threonine-protein kinase TBK1 isoform X3
  KO
K05410  TANK-binding kinase 1 [EC:2.7.11.10]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04014  Ras signaling pathway
tmu04137  Mitophagy - animal
tmu04140  Autophagy - animal
tmu04620  Toll-like receptor signaling pathway
tmu04621  NOD-like receptor signaling pathway
tmu04622  RIG-I-like receptor signaling pathway
tmu04623  Cytosolic DNA-sensing pathway
tmu04657  IL-17 signaling pathway
tmu04936  Alcoholic liver disease
tmu05014  Amyotrophic lateral sclerosis
tmu05022  Pathways of neurodegeneration - multiple diseases
tmu05135  Yersinia infection
tmu05160  Hepatitis C
tmu05161  Hepatitis B
tmu05162  Measles
tmu05163  Human cytomegalovirus infection
tmu05164  Influenza A
tmu05165  Human papillomavirus infection
tmu05167  Kaposi sarcoma-associated herpesvirus infection
tmu05168  Herpes simplex virus 1 infection
tmu05169  Epstein-Barr virus infection
tmu05170  Human immunodeficiency virus 1 infection
tmu05171  Coronavirus disease - COVID-19
tmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101345902
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101345902
   04137 Mitophagy - animal
    101345902
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101345902
   04621 NOD-like receptor signaling pathway
    101345902
   04622 RIG-I-like receptor signaling pathway
    101345902
   04623 Cytosolic DNA-sensing pathway
    101345902
   04657 IL-17 signaling pathway
    101345902
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    101345902
   05161 Hepatitis B
    101345902
   05160 Hepatitis C
    101345902
   05171 Coronavirus disease - COVID-19
    101345902
   05164 Influenza A
    101345902
   05162 Measles
    101345902
   05168 Herpes simplex virus 1 infection
    101345902
   05163 Human cytomegalovirus infection
    101345902
   05167 Kaposi sarcoma-associated herpesvirus infection
    101345902
   05169 Epstein-Barr virus infection
    101345902
   05165 Human papillomavirus infection
    101345902
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    101345902
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101345902
   05022 Pathways of neurodegeneration - multiple diseases
    101345902
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101345902
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101345902
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101345902
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tmu04131]
    101345902
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.10  IkappaB kinase
     101345902
Protein kinases [BR:tmu01001]
 Serine/threonine kinases: Other
  IKK family [OT]
   101345902
Membrane trafficking [BR:tmu04131]
 Autophagy
  Xenophagy
   Other xenophagy associated proteins
    101345902
SSDB
Motif
Pfam: TBK1_CCD1 Pkinase TBK1_ULD PK_Tyr_Ser-Thr Pkinase_fungal ABC1 DUF713 CEP63 Kinase-like
Other DBs
NCBI-GeneID: 101345902
NCBI-ProteinID: XP_004381607
UniProt: A0A2Y9DV50
LinkDB
Position
Unknown
AA seq 729 aa
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEESTTRHKVLIMEFCPCGSLYTVLEEPSNAYGLPESEFLIVLRDVV
GGMNHLRENGIIHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTTEENPIFVVSLEPLSTIGLMFEKISLPKVHPRYDLDGDASMAKAVTG
VVCYACRITSTLLLYQELTRKGVRWLIELIKDDYNEAVHKKTEVVITLEFCIRNIEKTVK
IYEKLMQINLEATELGEISDIHTKLLRLSSSQGTIETNLQDIGSKLSPGGLLADTWAHQE
GTHPRDRNVERLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FADECVKKYDAFLNKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPVYPSSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCI
NT seq 2190 nt   +upstreamnt  +downstreamnt
atgcagagcacttctaatcatctgtggcttttatctgatatcttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgatttatttgctatcaaagtattt
aataatataagcttcctccgaccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgttaaattatttgctattgaagaagagtcaaccacaaga
cataaagtacttattatggaattttgtccatgtgggagtctatatactgttttagaagag
ccatctaatgcctatgggctgccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagagaacggcataatccaccgtgatatcaagccaggaaat
atcatgcgtgttataggggaagatggacagtctgtgtataaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgaaagagcagtgttaagaaaagatcaccaaaagaaatacggagca
acagttgatctttggagcattggggtaacattttaccatgcagctactggatcactgcca
tttagaccatttgaagggcctcgtagaaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcggaaaatggaccaattgactggagt
ggagacatgcctgtctcttgtagtctttctaggggtctgcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaaatgttggggttttgatcagttttttgca
gaaactagtgatatacttcaccgaatgataattcatgttttttcactacaacaaatgaca
gctcataagatttatattcacagctataatactgctactgtatttcatgaactggtatat
aaacaaaccaaaattatttcttcaaatcaagaacttatctatgaaggacgacgcttagtt
ctagagcctggaagactggcacaacatttccctaaaacaacggaggaaaatcctatcttt
gtagtaagcctggaacctctgagcaccataggattaatgtttgaaaaaatttctcttcct
aaagtgcatccacgttatgatttagatggggatgctagcatggctaaggcagttacagga
gttgtgtgttatgcctgtagaatcaccagtactctactgctttaccaggaattaacgcga
aagggagtacgatggttgattgaattaattaaagatgactataatgaagctgttcacaaa
aagacagaagttgtgatcacattggaattctgcatcagaaacattgaaaaaactgtaaaa
atatatgaaaagttgatgcagatcaacttagaagcaacagagttaggtgaaatttcagat
atacacaccaaattgttgagactttccagttctcagggaacaatagaaaccaatcttcag
gatatcggaagcaaattgtctccaggtggattgctggcagatacatgggcacatcaagag
ggcactcatcccagagatagaaatgtagaaaggctacaagtcctgttaaattgcatcaca
gagatttactatcagttcaaaaaagacaaagcagaacgtaggctagcttataatgaagaa
caaattcacaaatttgataagcaaaaactgtattaccatgcaacaaaagctatgacccac
tttgcagatgagtgtgttaaaaagtatgatgcatttttgaataagtcagaagaatggatg
agaaagatgcttcatctaaggaaacagttgttatctctaactaatcagtgttttgatatt
gaagaagaagtatcaaagtatcaagactacactaatgagttacaagaaactttgcctcag
aaaatgtttgcagcctccagtggaatcaaacataccatgaccccagtctatccaagttct
aacacattagtggaaatgactcttggtatgaagaaattaaaggaagagatggaaggtgtg
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctctttgaccatggat
ggtggccttcgcaatgttgactgtatttag

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